# STOCKHOLM 1.0
#=GF ID 3.90.770.10/FF/000004
#=GF DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GF AC 3.90.770.10/FF/000004
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 61.583
#=GS Q9Y0F3/100-148_265-416      AC Q9Y0F3
#=GS Q9Y0F3/100-148_265-416      OS Leishmania major
#=GS Q9Y0F3/100-148_265-416      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS Q9Y0F3/100-148_265-416      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q9Y0F3/100-148_265-416      DR GO; GO:0004420; GO:0005739; GO:0010142; 
#=GS Q19207/167-216_335-486      AC Q19207
#=GS Q19207/167-216_335-486      OS Caenorhabditis elegans
#=GS Q19207/167-216_335-486      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS Q19207/167-216_335-486      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A3P3ZD29/100-148_265-416  AC A0A3P3ZD29
#=GS A0A3P3ZD29/100-148_265-416  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3ZD29/100-148_265-416  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A3P3ZD29/100-148_265-416  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS H3F5U5/182-231_350-493      AC H3F5U5
#=GS H3F5U5/182-231_350-493      OS Pristionchus pacificus
#=GS H3F5U5/182-231_350-493      DE Uncharacterized protein
#=GS H3F5U5/182-231_350-493      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS A0A3S7X3U0/100-148_265-416  AC A0A3S7X3U0
#=GS A0A3S7X3U0/100-148_265-416  OS Leishmania donovani
#=GS A0A3S7X3U0/100-148_265-416  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A3S7X3U0/100-148_265-416  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A088SFF2/100-148_265-416  AC A0A088SFF2
#=GS A0A088SFF2/100-148_265-416  OS Leishmania panamensis
#=GS A0A088SFF2/100-148_265-416  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A088SFF2/100-148_265-416  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9B193/100-148_265-416      AC E9B193
#=GS E9B193/100-148_265-416      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9B193/100-148_265-416      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS E9B193/100-148_265-416      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4I602/100-148_265-416      AC A4I602
#=GS A4I602/100-148_265-416      OS Leishmania infantum
#=GS A4I602/100-148_265-416      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A4I602/100-148_265-416      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A1E1J4G7/100-148_265-416  AC A0A1E1J4G7
#=GS A0A1E1J4G7/100-148_265-416  OS Leishmania guyanensis
#=GS A0A1E1J4G7/100-148_265-416  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A1E1J4G7/100-148_265-416  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS A8XLV8/170-219_338-489      AC A8XLV8
#=GS A8XLV8/170-219_338-489      OS Caenorhabditis briggsae
#=GS A8XLV8/170-219_338-489      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A8XLV8/170-219_338-489      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS A0A2G5ULT3/177-226_345-496  AC A0A2G5ULT3
#=GS A0A2G5ULT3/177-226_345-496  OS Caenorhabditis nigoni
#=GS A0A2G5ULT3/177-226_345-496  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A2G5ULT3/177-226_345-496  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A2A6B4K8/182-231_350-503  AC A0A2A6B4K8
#=GS A0A2A6B4K8/182-231_350-503  OS Pristionchus pacificus
#=GS A0A2A6B4K8/182-231_350-503  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A2A6B4K8/182-231_350-503  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS A4HIQ3/100-148_265-416      AC A4HIQ3
#=GS A4HIQ3/100-148_265-416      OS Leishmania braziliensis
#=GS A4HIQ3/100-148_265-416      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A4HIQ3/100-148_265-416      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS E9BM66/100-148_265-416      AC E9BM66
#=GS E9BM66/100-148_265-416      OS Leishmania donovani BPK282A1
#=GS E9BM66/100-148_265-416      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS E9BM66/100-148_265-416      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GF SQ 14
Q9Y0F3/100-148_265-416              PVGLAGPLLLDG-KEVALPMATTEGALVASAHRGARAINLSGGCRTAVLKKSVVAEAVIKRDVVESVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTVDKAGE-DLVISLMMPSIEVGAVGGGTGLSSQRAMLELMGCAGSNKED--PGAHSRQIARVVAGAVICGELSLLSGLA
Q19207/167-216_335-486              PVGVAGPLTLNGTSEIYVPMATTEGALIASTNRGMNVIRAAGGVETSIFNRSVVAECLIPREVVTKTLRTTPEQLAYLTTTKLHIGSSRAGAVGGSNAHAANIVAAIFIATGQDAAQVVSSSMCSTRMEVTADKNLYVSCTLPCVEVGTVGGGTILAPQRACLESLGCAGPNKEQ--PGQNAERLAEVIAATVLAGELSLMAAL-
A0A3P3ZD29/100-148_265-416          PVGLAGPLLLDG-KEVGLPMATTEGALVASTHRGARAINLSGGCRTAVLKKSVVAEAVIKRCVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTIDKVGE-DLMISLTMPSIEVGAVGGGTGLSSQSAMLELMGCAGANKED--PGANSRQIARVVAGAVICGELSLMAGLA
H3F5U5/182-231_350-493              PVGVAGPLKINNGTPLHVPMATTEGALVASTNRGCTAIMKSGGVSAHVYARSVVADCVLPASVVRSVLKTTPRAMAEAGRAKLDSGSAAAGAIGGANAHAANI----------DAAQVVSSSMCATRLEETEDGSLYASVTLPCMECGTVGGGTVLPAQRACLEMLGVAGPSPSSCAPGTNAATLAEIIASTVLAGELSLMAAL-
A0A3S7X3U0/100-148_265-416          PVGLAGPLLLDG-KEVALPMATTEGALVASAHRGARAINLSGGCRTAVLKKSVVAEAVIKRDVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQIVESATCMTTVDKAGE-DLVISLTMPSIEVGAVGGGTGLSSQRAMLELMGCAGSNKED--PGANSRQIARVVAGAVICGELSLLSGLA
A0A088SFF2/100-148_265-416          PVGLAGPLLLDG-KEVGLPMATTEGALVASTHRGARAINLSGGCRTAVLKKSVVAEAVIKRCVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTIDKVGE-DLMISLTMPSIEVGAVGGGTGLSSQSAMLELMGCAGANKED--PGANSRQIARVVAGAVICGELSLMAGLA
E9B193/100-148_265-416              PVGLAGPLLLDG-EEVALPMATTEGALVASAHRGARAINLSGGCRTAVLKKSVVAEAVIKRDVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTVDKAGD-DLVISLTMPSIEVGAVGGGTGLSSQRAMLELMGCAGSNKED--PGANSRQIARVVAGAVVCGELSLLSGLA
A4I602/100-148_265-416              PVGLAGPLLLDG-KEVALPMATTEGALVASAHRGARAINLSGGCRTAVLKKSVVAEAVIKRDVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQIVESATCMTTVDKAGE-DLVISLTMPSIEVGAVGGGTGLSSQRAMLELMGCAGSNKED--PGANSRQIARVVAGAVICGELSLLSGLA
A0A1E1J4G7/100-148_265-416          PVGLAGPLLLDG-KEVGLPMATTEGALVASTHRGARAINLSGGCRTAVLKKSVVAEAVIKRCVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTIDKVGE-DLMISLTMPSIEVGAVGGGTGLSSQSAMLELMGCAGANKED--PGANSRQIARVVAGAVICGELSLMAGLA
A8XLV8/170-219_338-489              PVGVAGPLSINGSTDIYVPMATTEGALIASTNRGMNVIREAGGVETSVVNRSVVAECLIKRDTVIKTLRTTPEALAYLTTTKLHIGSARAGTIGGSNAHAANIVAAIFIATGQDAAQVVSSAMCSTRMEVTDEKDLYVSCTLPCVEVGTVGGGTILSPQRACLECLECAGPNHER--PGGNAERLAEIIAATVLAGELSLMAAL-
A0A2G5ULT3/177-226_345-496          PVGVAGPLSINGSTDIYVPMATTEGALIASTNRGMNVIREAGGVETSVVNRSVVAECLIKRDTVIKTLRTTPEALAYLTTTKLHIGSARAGTIGGSNAHAANIVAAIFIATGQDAAQVVSSAMCSTRMEVTDEKDLYVSCTLPCVEVGTVGGGTILSPQRACLESLECAGPNHER--PGGNAERLAEIIAATVLAGELSLMAAL-
A0A2A6B4K8/182-231_350-503          PVGVAGPLKINNGTPLHVPMATTEGALVASTNRGCTAIMKSGGVSAHVYARSVVADCVLPASVVRSVLKTTPRAMAEAGRAKLDSGSAAAGAIGGANAHAANIVAAIFIATGQDAAQVVSSSMCATRLEETEDGSLYASVTLPCMECGTVGGGTVLPAQRACLEMLGVAGPSPSSCAPGTNAATLAEIIASTVLAGELSLMAAL-
A4HIQ3/100-148_265-416              PVGLAGPLLLDG-KEVGLPMATTEGALVASTHRGARAINLSGGCRTAVLKKSVVAEAVIKRCVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQVVESATCMTTIDKVGE-DLMISLTMPSIEVGAVGGGTGLSSQSAMLELMGCAGANKED--PGANSRQIARVVAGAVICGELSLMAGLA
E9BM66/100-148_265-416              PVGLAGPLLLDG-KEVALPMATTEGALVASAHRGARAINLSGGCRTAVLKKSVVAEAVIKRDVVEGVLKCTVDSVVSLNVTKNLRGSALAGSIGGFNAHAANIVAALYIATGQDPAQIVESATCMTTVDKAGE-DLVISLTMPSIEVGAVGGGTGLSSQRAMLELMGCAGSNKED--PGANSRQIARVVAGAVICGELSLLSGLA
#=GC scorecons                      9996999936661456369999999997996699446943699547484479999756756469346975955556465479434997499589949999999666456666696997959659495574557159459486966969699999496596959946769956464009948644695779569659999976691
#=GC scorecons_70                   ********_***_____**************_**__**__***__*_*__******_**_*_**__***_*______*__**___***_**_***_**********__******_****_**_*_*__*___*__*__*_***__*_*******_*__***_**_**_**_*_*___**_*___**_***_**__*******_*_
#=GC scorecons_80                   ***_****__________************__**___*___**____*___*****_______*___**_*__________*___***_**_***_*******__________*_****_*__*_*_________*__*_*_*__*_*_*****_*__*_*_**____**_______**_*____*___*__*__******__*_
#=GC scorecons_90                   ***_****__________*********_**__**___*___**____*___****________*___*__*__________*___**__**_***_*******__________*_**_*_*__*_*_________*__*_*_*__*_*_*****_*__*_*_**____**_______**_*____*___*__*__*****___*_
//