# STOCKHOLM 1.0 #=GF ID 3.90.1150.10/FF/000114 #=GF DE Serine hydroxymethyltransferase #=GF AC 3.90.1150.10/FF/000114 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 90.898 #=GS Q8ZYF9/13-31_285-387 AC Q8ZYF9 #=GS Q8ZYF9/13-31_285-387 OS Pyrobaculum aerophilum str. IM2 #=GS Q8ZYF9/13-31_285-387 DE Serine hydroxymethyltransferase #=GS Q8ZYF9/13-31_285-387 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; Pyrobaculum aerophilum; #=GS O59347/9-31_288-408 AC O59347 #=GS O59347/9-31_288-408 OS Pyrococcus horikoshii OT3 #=GS O59347/9-31_288-408 DE Serine hydroxymethyltransferase #=GS O59347/9-31_288-408 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus horikoshii; #=GS Q5JF06/12-33_290-410 AC Q5JF06 #=GS Q5JF06/12-33_290-410 OS Thermococcus kodakarensis KOD1 #=GS Q5JF06/12-33_290-410 DE Serine hydroxymethyltransferase #=GS Q5JF06/12-33_290-410 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus kodakarensis; #=GS A9A3Y9/12-34_296-418 AC A9A3Y9 #=GS A9A3Y9/12-34_296-418 OS Nitrosopumilus maritimus SCM1 #=GS A9A3Y9/12-34_296-418 DE Serine hydroxymethyltransferase #=GS A9A3Y9/12-34_296-418 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Nitrosopumilus maritimus; #=GS B1L5K9/10-31_295-416 AC B1L5K9 #=GS B1L5K9/10-31_295-416 OS Candidatus Korarchaeum cryptofilum OPF8 #=GS B1L5K9/10-31_295-416 DE Serine hydroxymethyltransferase #=GS B1L5K9/10-31_295-416 DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; #=GS A0CF19/16-40_301-407 AC A0CF19 #=GS A0CF19/16-40_301-407 OS Paramecium tetraurelia #=GS A0CF19/16-40_301-407 DE Uncharacterized protein #=GS A0CF19/16-40_301-407 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS A9UQD9/33-54_314-415 AC A9UQD9 #=GS A9UQD9/33-54_314-415 OS Monosiga brevicollis #=GS A9UQD9/33-54_314-415 DE Uncharacterized protein #=GS A9UQD9/33-54_314-415 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS S2EVH9/12-34_296-417 AC S2EVH9 #=GS S2EVH9/12-34_296-417 OS Candidatus Nitrosarchaeum limnium BG20 #=GS S2EVH9/12-34_296-417 DE Serine hydroxymethyltransferase #=GS S2EVH9/12-34_296-417 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosarchaeum; Candidatus Nitrosarchaeum limnium; #=GS A0A2Z2HT19/12-34_296-416 AC A0A2Z2HT19 #=GS A0A2Z2HT19/12-34_296-416 OS Candidatus Nitrosomarinus catalina #=GS A0A2Z2HT19/12-34_296-416 DE Serine hydroxymethyltransferase #=GS A0A2Z2HT19/12-34_296-416 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Candidatus Nitrosomarinus; Candidatus Nitrosomarinus catalina; #=GS I3D4W5/12-34_296-418 AC I3D4W5 #=GS I3D4W5/12-34_296-418 OS Candidatus Nitrosopumilus salaria BD31 #=GS I3D4W5/12-34_296-418 DE Serine hydroxymethyltransferase #=GS I3D4W5/12-34_296-418 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Candidatus Nitrosopumilus salaria; #=GS A0A0D5BYZ4/12-34_296-418 AC A0A0D5BYZ4 #=GS A0A0D5BYZ4/12-34_296-418 OS Candidatus Nitrosopumilus adriaticus #=GS A0A0D5BYZ4/12-34_296-418 DE Serine hydroxymethyltransferase #=GS A0A0D5BYZ4/12-34_296-418 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Candidatus Nitrosopumilus adriaticus; #=GS A0A218P264/12-33_290-410 AC A0A218P264 #=GS A0A218P264/12-33_290-410 OS Thermococcus celer Vu 13 = JCM 8558 #=GS A0A218P264/12-33_290-410 DE Serine hydroxymethyltransferase #=GS A0A218P264/12-33_290-410 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus celer; #=GS Q9V1B2/9-31_288-408 AC Q9V1B2 #=GS Q9V1B2/9-31_288-408 OS Pyrococcus abyssi GE5 #=GS Q9V1B2/9-31_288-408 DE Serine hydroxymethyltransferase #=GS Q9V1B2/9-31_288-408 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus abyssi; #=GS C5A6G2/10-31_288-408 AC C5A6G2 #=GS C5A6G2/10-31_288-408 OS Thermococcus gammatolerans EJ3 #=GS C5A6G2/10-31_288-408 DE Serine hydroxymethyltransferase #=GS C5A6G2/10-31_288-408 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus gammatolerans; #=GS I6V3U2/9-31_288-408 AC I6V3U2 #=GS I6V3U2/9-31_288-408 OS Pyrococcus furiosus COM1 #=GS I6V3U2/9-31_288-408 DE Serine hydroxymethyltransferase #=GS I6V3U2/9-31_288-408 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus furiosus; #=GS Q8U039/9-31_288-408 AC Q8U039 #=GS Q8U039/9-31_288-408 OS Pyrococcus furiosus DSM 3638 #=GS Q8U039/9-31_288-408 DE Serine hydroxymethyltransferase #=GS Q8U039/9-31_288-408 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus furiosus; #=GS F3KLZ3/12-34_296-417 AC F3KLZ3 #=GS F3KLZ3/12-34_296-417 OS Candidatus Nitrosarchaeum limnium SFB1 #=GS F3KLZ3/12-34_296-417 DE Serine hydroxymethyltransferase #=GS F3KLZ3/12-34_296-417 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosarchaeum; Candidatus Nitrosarchaeum limnium; #=GF SQ 17 Q8ZYF9/13-31_285-387 -------ILQHNTWRRKETINLIASERIVENAKALAEALAEEGVTPVGERLGYTKTHQVAVDVSKF-------GGGDKVARLLEEANIIVNKNALPWD----KSVLKPSGIRMGVQEMTRFGMGKGEMKEIAKFIARVLK----------------- O59347/9-31_288-408 --KVLHFIEEHEKW-RSHTINLIASE-IVKNAKALAEALAEEGFKVIGEDQGYTKSHQVIVDVSDLH-----PAGGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMMEDEMKEIAHFMKRVLIDKEDPKKVRKDVYYF-- Q5JF06/12-33_290-410 ---VLGFIEDHENW-RKHTINLIASE-IVKNAKALAEALAEEGFKVIGEDKGYTESHQVIVDVSDLH-----PAAGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMMEDEMKEIARFIRRVLIDKEDPAKVRRDVYGF-- A9A3Y9/12-34_296-418 --KIFAKLKEHHKW-FENSIPLIASE-VIKNAKSFAEALSDAGFKVLGESRGFTQSHQIAVNVLDY-------SDGGKVEADLEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKKNEMQEIASFIKQVVIEKKDPKKLLSKVKSFRK B1L5K9/10-31_295-416 ---VKSSILEHHKW-FDSSLPMIASE-VVRNAKALAQALHDEGFSVVAEHLGFTQSHQVLLDVDAL-------GGGHRCEKLLEEANIIVNRNLLPWDIKRGRSFKDPGGLRLGVSELTRLGMGEEEMKEIAKLYRKVLLDREDPKKVAGEVSELR- A0CF19/16-40_301-407 DIEIYQLIEKEKNL-QQNSINLIPSEDVVDNNKHFAAEFQRLGFDLIA---GGTENHLILVDLRKFN------VDAVKMEYILSQINIQCNKQLVPFD-----TVPQPRALRVGSIPLSVRQASKEHFTRVAQIIKESV-------ELVQTVTV--- A9UQD9/33-54_314-415 ---VEQAVRDETRR-QRDELVLIPSELVVHNSKVFADALVSQGFSL---EYGGTENHMVLIDLKKYRVADGCPLDGETASRLLENVGIIVNKNTLPGD----ENASDSSGLRVATPWLTQRGVTDAQIHELATIM---------------------- S2EVH9/12-34_296-417 --KIFSKLKEHHKW-FENSIPLIASE-VIKNAKVFAESLNDLGFKVLGESRGFTESHQIAVNVLDY-------SDGGKVEADLEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKQNEMKEIASYMKEVVIEKKDPKKILSKVKAFR- A0A2Z2HT19/12-34_296-416 --KIFAKLKEHHKW-FENSIPLIASE-VIKNAKIFAEALNDAGFKVLGESRGYTQSHQIAVNVLDY-------SDGGKVEAELEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKENEMKEIATFIKQIIIEKKDPKKVLPKVKSW-- I3D4W5/12-34_296-418 --KIFRKLKEHHKW-FENSIPLIASE-VIKNAKAFAEALSNAGFKVLGESRGFTESHQIAVNVLDY-------SDGGKVEANLEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKKNEMEEIASFIKQVVIEKKDPKKILSKVKSFRK A0A0D5BYZ4/12-34_296-418 --KIFGKLKEHHKW-FENSIPLIASE-VIKNAKSLADALSNAGFKVLGESKGFTKSHQIAVNVLDY-------SDGGKVEADLEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKKNEMEEIASLIKNIVIEKKDPKKILSKVKSFRK A0A218P264/12-33_290-410 ---VLNFIEEHENW-RSHTINLIASE-IVKNAKALAEALAEEGFKVIGEDKGYTESHQVIVDVSDLH-----PAAGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMLEDDMKEIAKFIRRVLIDKEDPKKVERDVFYF-- Q9V1B2/9-31_288-408 --KVLHFIEEHEKW-RSHTINLIASE-IVKNAKALAEALAEEGFKVIGEDQGYTKSHQVIVDVSDLH-----PAGGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMMEDEMKEIAHFMKRVLLDKEDPKKVRKDVYYF-- C5A6G2/10-31_288-408 ---VLNFIEDHEHW-RAHTINLIASE-VVKNAKALAEALAEEGFKVIGEDKGYTESHQVIVDVSDLH-----PAAGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMFEDDMKEIAHFIRRVLIDKEDPKKVRRDVYGF-- I6V3U2/9-31_288-408 --KVLNFIEEHEKW-RSHTINLIASE-IVKNAKALAEALAEEGFKVIGEDQGYTKSHQVIVDVSDLH-----PAGGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMMEDEMREIAHFIKRVLIDKEDPKKVRKDVYYF-- Q8U039/9-31_288-408 --KVLNFIEEHEKW-RSHTINLIASE-IVKNAKALAEALAEEGFKVIGEDQGYTKSHQVIVDVSDLH-----PAGGGWAAPLLEEAGIILNKNLLPWDPL--EKVNEPSGLRIGVQEMTRVGMMEDEMREIAHFIKRVLIDKEDPKKVRKDVYYF-- F3KLZ3/12-34_296-417 --KIFSKLKEHHKW-FENSIPLIASE-VIKNAKVFAESLNDLGFKVLGESRGFTESHQIAVNVLDY-------SDGGKVEADLEKANIIVNRQLIPGDIKAGRNYFHPGGIRLGVSEITRLGMKQNEMKEIASYMKEVVIEKKDPKKILSKVKAFR- #=GC scorecons 0026332646645603445748979907759694696684549856455339595696747673551000001457545434975659759756694922014443475769576465764763546757793565455434344454223622300 #=GC scorecons_70 _______*__*__*_____*_*****_**_***_*****___**_*_____*_*_****_***____________*______**_*_**_**_*_*_*_________*_***_**___**_**___**_***__*______________________ #=GC scorecons_80 ___________________*_**_**_**_*_*__*__*___**_______*_*__*___*_*____________*______**___**_*____*_*_________*_*_*_*____*__*_______***_________________________ #=GC scorecons_90 _____________________**_**____*_*__*______*________*_*__*_________________________*____*__*____*_*_____________*___________________*_________________________ //