# STOCKHOLM 1.0 #=GF ID 3.60.40.10/FF/000069 #=GF DE Pyruvate dehydrogenase #=GF AC 3.60.40.10/FF/000069 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 89.233 #=GS Q9W3Q1/29-371_405-464 AC Q9W3Q1 #=GS Q9W3Q1/29-371_405-464 OS Drosophila melanogaster #=GS Q9W3Q1/29-371_405-464 DE GM14286p #=GS Q9W3Q1/29-371_405-464 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9W3Q1/29-371_405-464 DR GO; GO:0004721; GO:0004741; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0006090; GO:0006470; #=GS Q9N4M0/12-355_388-450 AC Q9N4M0 #=GS Q9N4M0/12-355_388-450 OS Caenorhabditis elegans #=GS Q9N4M0/12-355_388-450 DE Pyruvate Dehydrogenase Phosphatase homolog #=GS Q9N4M0/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS W4ZCR4/73-507 AC W4ZCR4 #=GS W4ZCR4/73-507 OS Strongylocentrotus purpuratus #=GS W4ZCR4/73-507 DE Uncharacterized protein #=GS W4ZCR4/73-507 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS A7S1G8/1-390 AC A7S1G8 #=GS A7S1G8/1-390 OS Nematostella vectensis #=GS A7S1G8/1-390 DE Predicted protein #=GS A7S1G8/1-390 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS A7RHC1/1-394 AC A7RHC1 #=GS A7RHC1/1-394 OS Nematostella vectensis #=GS A7RHC1/1-394 DE Predicted protein #=GS A7RHC1/1-394 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS T1G9K4/55-417_448-499 AC T1G9K4 #=GS T1G9K4/55-417_448-499 OS Helobdella robusta #=GS T1G9K4/55-417_448-499 DE Uncharacterized protein #=GS T1G9K4/55-417_448-499 DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; #=GS A0A139WKL9/10-439 AC A0A139WKL9 #=GS A0A139WKL9/10-439 OS Tribolium castaneum #=GS A0A139WKL9/10-439 DE [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial-like Protein #=GS A0A139WKL9/10-439 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7PNG1/6-347_379-434 AC Q7PNG1 #=GS Q7PNG1/6-347_379-434 OS Anopheles gambiae #=GS Q7PNG1/6-347_379-434 DE AGAP008349-PA #=GS Q7PNG1/6-347_379-434 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS A0A1S4GY06/35-378_410-465 AC A0A1S4GY06 #=GS A0A1S4GY06/35-378_410-465 OS Anopheles gambiae #=GS A0A1S4GY06/35-378_410-465 DE Pyruvate dehyrogenase phosphatase catalytic subunit 1 #=GS A0A1S4GY06/35-378_410-465 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS H3DVH0/16-404 AC H3DVH0 #=GS H3DVH0/16-404 OS Pristionchus pacificus #=GS H3DVH0/16-404 DE Uncharacterized protein #=GS H3DVH0/16-404 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A8WJL9/12-355_388-450 AC A8WJL9 #=GS A8WJL9/12-355_388-450 OS Caenorhabditis briggsae #=GS A8WJL9/12-355_388-450 DE Protein CBG23932 #=GS A8WJL9/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS G0PBU3/12-355_388-450 AC G0PBU3 #=GS G0PBU3/12-355_388-450 OS Caenorhabditis brenneri #=GS G0PBU3/12-355_388-450 DE Uncharacterized protein #=GS G0PBU3/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; #=GS A0A1I7T0Z8/12-355_388-450 AC A0A1I7T0Z8 #=GS A0A1I7T0Z8/12-355_388-450 OS Caenorhabditis tropicalis #=GS A0A1I7T0Z8/12-355_388-450 DE Uncharacterized protein #=GS A0A1I7T0Z8/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis tropicalis; #=GS A0A2G5SBL7/12-355_388-450 AC A0A2G5SBL7 #=GS A0A2G5SBL7/12-355_388-450 OS Caenorhabditis nigoni #=GS A0A2G5SBL7/12-355_388-450 DE Uncharacterized protein #=GS A0A2G5SBL7/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A261AU81/12-355_388-450 AC A0A261AU81 #=GS A0A261AU81/12-355_388-450 OS Caenorhabditis latens #=GS A0A261AU81/12-355_388-450 DE Uncharacterized protein #=GS A0A261AU81/12-355_388-450 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; #=GS E3MGK7/12-355_388-451 AC E3MGK7 #=GS E3MGK7/12-355_388-451 OS Caenorhabditis remanei #=GS E3MGK7/12-355_388-451 DE CRE-PDP-1 protein #=GS E3MGK7/12-355_388-451 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; #=GS A0A084W5U1/39-388_420-475 AC A0A084W5U1 #=GS A0A084W5U1/39-388_420-475 OS Anopheles sinensis #=GS A0A084W5U1/39-388_420-475 DE AGAP008349-PA-like protein #=GS A0A084W5U1/39-388_420-475 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS W5JEK2/37-380_412-467 AC W5JEK2 #=GS W5JEK2/37-380_412-467 OS Anopheles darlingi #=GS W5JEK2/37-380_412-467 DE Pyruvate dehydrogenase #=GS W5JEK2/37-380_412-467 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Nyssorhynchus; darlingi group; Anopheles darlingi; #=GS A0A182Y3A0/35-395_428-483 AC A0A182Y3A0 #=GS A0A182Y3A0/35-395_428-483 OS Anopheles stephensi #=GS A0A182Y3A0/35-395_428-483 DE Uncharacterized protein #=GS A0A182Y3A0/35-395_428-483 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles stephensi; #=GS A8XF12/12-130_180-403_436-498 AC A8XF12 #=GS A8XF12/12-130_180-403_436-498 OS Caenorhabditis briggsae #=GS A8XF12/12-130_180-403_436-498 DE Protein CBG12191 #=GS A8XF12/12-130_180-403_436-498 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS B4IHN9/29-371_405-464 AC B4IHN9 #=GS B4IHN9/29-371_405-464 OS Drosophila sechellia #=GS B4IHN9/29-371_405-464 DE GM17460 #=GS B4IHN9/29-371_405-464 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS A0A1W4V6G4/29-371_405-465 AC A0A1W4V6G4 #=GS A0A1W4V6G4/29-371_405-465 OS Drosophila ficusphila #=GS A0A1W4V6G4/29-371_405-465 DE pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial #=GS A0A1W4V6G4/29-371_405-465 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3NTS5/29-371_405-464 AC B3NTS5 #=GS B3NTS5/29-371_405-464 OS Drosophila erecta #=GS B3NTS5/29-371_405-464 DE Uncharacterized protein #=GS B3NTS5/29-371_405-464 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4Q0T1/29-371_405-464 AC B4Q0T1 #=GS B4Q0T1/29-371_405-464 OS Drosophila yakuba #=GS B4Q0T1/29-371_405-464 DE Uncharacterized protein #=GS B4Q0T1/29-371_405-464 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GF SQ 24 Q9W3Q1/29-371_405-464 PQLPQLSPYD---VNLVLRENEFVYNF---PVDGVIRSYETNQLGSNWPCEDSRTEASFLHR-NGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGADS--QSFLKCHNDN------------------VDFVSMIKPMYEASFLKYVNQ-LLETP-QR----DVSSE----LVNAFLQLDEEISQEALTSN--------DVRTMNVALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVL----PMFGVQAMAPN-YYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKI----------------------------------QNAATHLIRHALGGTDYGI--EHSKISYYLT-LPRDAVRLYRDDITITVIYFNSEHIAKLHSD- Q9N4M0/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCLSS-RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEVVDYPSDQRLEWLFSSSDGHLPN----AFKGRE------------TQHIAEYHKQFKKNANA----------YTGTVREA----LKLAFETCDKDLAENALPSAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LFTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEDDE W4ZCR4/73-507 RMNPVLTPEQ---TSEALQQNEVSVHFDEESSPQAVQRYDSNQLFSNKPGEDRRAIAECMFT-NGVLFGVFDGHGGTACAQAISERLFNYIVAETLPFQTLPKALARLQSGEMNDLVKWHRHP-----------------NEYKLQATADLYKESLIKYVQANLSVDV-LDD--DDTADV----LKTAFDRLDNDFSTEAMRATTEPL----GIEPVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSK-GYGAWESIPLTVDHNVQNLDEVNRIKGGHPSHESTTVIKNGRLLGELMPLRAFGNIRFKWTAEMQRTLM-----RTFIGYLPPKS-FHTPPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKASSSYGV-QEGAALKDVMKDLKERMD--ILKSLD-TNSATHLIRYSLCGVGNDF--DLNKLAEVLS-LPDAIARQHRDDMTVTVIYFDS---------- A7S1G8/1-390 -----------------------------------VLYYDSNILPSNEPTEDRNAECEMLSS-NGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTQFEKEIVEDLLISRFSDKSGPK---TSVANDS-----SSDNDLSKKQDVFHTGPKYMVQA-LQARL-ENGCRLSMDEA----LSFAFTHLDDDIVTEAIPVK---V----LDDSFLAGASGACTIAAYIEGDQLLVANAGDCRAVLGSVN-GDGSWVATPLSADQTANSREEFQRVWSQHPGEEA-TVIKNGRLLGQLQPLRAFGDIQYKWDRVTHNHILT----QVYGGPIVPPHVYKSPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSD---------------------------VLE-HNAASHLIRHAIGGN------DHHFVAQMLL-VPDQYRRMWRDDITVTVVFFNSEEVKISS--- A7RHC1/1-394 ----MISDGE---VNAMISRLEKSGKI----DTGIIDRYETNQLASNQPMEDRKFVVRLLHQDGGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRHVLLAHPD------LMPKLTDY-------------------------------------------LTITK-----NEDHFRS----IREAYIRLDQDIRNEAVKESKSKLPEGSSCHAFDAANAGACALVAYIQGTELFLANAGDCRAVLGVQG-EDGCWSAMQLSSDHTAGNPEEVQRILNQHPPEESTTVIRFERLLGRLAPLRAFGDARFKWDKKTQNKVYSKSSLNPMSE---VEH-FYTPPYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDTSKGVLPQDITFNE------------QELPCDLNNAASCLVREALGGD------DHVAVSTTLS-IPYPDVRMYRDDISVIVVFFNWERMESV---- T1G9K4/55-417_448-499 GYTPVLSPAQ---VTSMLTSNQATHHY---PVGGPVTRFDSSQLSSNNPIEDRRAVGKLVQT-GGLLFGVFDGHGGAACAQAVSERLFDYIALCLLSPKQLEHYSRLMRTSEPLSLLDLYRFQ-----------------NDYFNEDLVEFYSQSLQKFVVEHLSTTG-LEDENDEIANSIIGYLKTAFRRLDDDISYEAMPVGGK-I----NEDLMSIAMSGSCCCTVHILGKTLHTANIGDCRAVVGSLG-QDGHWVPKVLTVDHNVHNEKEAKRIHDSHPKSEWISLIRNGRLLSQLIPVRAFGDVRFKWPVKDLKNLVSLLGNSPYAQSIIPAH-YYSPPYLIARPEVKSHELTDSDHFVIVASDGLWEMLSNEKAVEIVGDHITGKQAT-------------------------------D-SNGAVHLLRHALG-------YEHRKVSEMLT-FPPQISRSYRDDITIIIVYFDTKFLAKQ---- A0A139WKL9/10-439 --------FQ---VDNILRANEYTHEF----SNGSVKSYDSNQLASNNPIEDTRAEASCLIT-SGLLVGIFDGHGGGACAQVLAKRLFHYITACLVPHDHLTEYVASLASSNPMRLIESYNDK------------------VQLVDDVRELYDKSFKVFLKD-LAEVGHKQG--FEMSKA----LEKAFLRLDDDLSKEALPVDGK-I----NMKTLSVAMSGAVACVGHIDGAHLHIANVGDCCAVLGTLS-DTNSWIAKKLTQEHNYQNKSEVERIIKAHPYNESNTVIRVGRLLSQLAPFRAMGDFCYKWSKEIMYEVVV----KQFGKTAIPPN-YHTPPYLIATPEVTHHRLTPRDKFLVIASDGLWDIVSPLEVVRLVGEHMKGKPTLSSLKLPRKNMTLSEINELLLQRKEGLKTKPKD-SNAATHLIRNALGGTEYGI--DHGELSEMLS-LPDDVVRVFRDDITITVVYFDSEYLRH----- Q7PNG1/6-347_379-434 ---SLSAPRQ---VNCILRTNEHTQEF----FGGSVKSYDSNQLASNSPIEDSRSEASCVHT-SGLLLGIFDGHGGPACSQVISKRLMRYIAASLVPPDDLRQHVLNGAQS--FSFLSCHNDK------------------ARCGYEIKELYEKSFHQFANE-LTNTT-LAG--FQMHQT----LENAFIRLDQDLSREAIEMP--------SLRTMSVAMSGAVALVAHIDGPHLHVASVGDCSAVLGTVT-DTGQWMAKKLTNEHNSDNVGEVRRLLSEHPATERDTVIRGERLLGQLAPLRAMGDFRYKWSREQLEQLVV----PQFGEQVIAPY-YLTPPYLSACPEITHHILTPRDKFLIIASDGLWDTMSAMQTVHLVGEHMYGKAFLQ--------------------------------RNAATHLIRNALGGTEYGV--EHSKLSHMLS-LPQDIVRLFRDDITITVVYFDSEYLRN----- A0A1S4GY06/35-378_410-465 -GPPKLSPYD---VNCILRTNEHTQEF----FGGSVKSYDSNQLASNSPIEDSRSEASCVHT-SGLLLGIFDGHGGPACSQVISKRLMRYIAASLVPPDDLRQHVLNGAQS--FSFLSCHNDK------------------LEFVSEIKELYEKSFHQFANE-LTNTT-LAG--FQMHQT----LENAFIRLDQDLSREAIEMP--------SLRTMSVAMSGAVALVAHIDGPHLHVASVGDCSAVLGTVT-DTGQWMAKKLTNEHNSDNVGEVRRLLSEHPATERDTVIRGERLLGQLAPLRAMGDFRYKWSREQLEQLVV----PQFGEQVIAPY-YLTPPYLSACPEITHHILTPRDKFLIIASDGLWDTMSAMQTVHLVGEHMYGKAFLQ--------------------------------RNAATHLIRNALGGTEYGV--EHSKLSHMLS-LPQDIVRLFRDDITITVVYFDSEYLRN----- H3DVH0/16-404 --GMRTARKA---ADDRLRQFERSFEI----NEGPIKRVDICQLAANQPIEDFYSLGRCVSS-RALLLAVCDGHGGSACSRYISAHLMAYVCAAVLDKHVQTEVPVDKRLEWIFSSSDAHLNQ----ENNLRN-------GAYAIEARLHSFHAKFK---NM----------DTKTVKSS----LQAAFLALDEDIAQAALPDAKGRV----HRARAAIAASGSCASLAHIRSRSLHVANAGDCAAVLGVES-ASGIVSSLQLSRPHCVENADEVARIKAAHPSSESH-VLRGGRLLGELYPLRAFGDVRYKWPLELQKAVL-----GPLGSP-PPPN-LLTPPYLTAMPEVFHHKLTKSDRFLIVASDGLWEWFDADTAVRLVRDHSLGALSLQPYEP-SPDLTLGEVYEQLKARRAGERKRPLD-TNSATHLLRHALGGA------------------------------------------------- A8WJL9/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCISS-RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEIGDYSPDQRLEWLFSSSDGHLPN----AFKSRE------------TRNIAAYHKEFKKNPNT----------YTGTVREA----LKLAFETCDKDLGDNALPNAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVQRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LYTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEEDE G0PBU3/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANV----EDEAIMRVDTCQLAANNPIEDFYSAAKCLSS-RAFLFGVFDGHGGQQCSRHISTNLYPYVCASVLKKHEIADYPPDQRLEWLFSSSDGHLPN----TFKSRE------------TRNISLYHSDFKKNANA----------YTGTVREA----LKLAFETCDRDLGENALPNAKGVI----DRHAAMIAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LFTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNDSFLDGHEDDE A0A1I7T0Z8/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANI----EDDAIMRVDTCQLAANNPIEDFYSAAKCLSS-KAFLFGVFDGHGGQQCSRHISTNLYPYICASVLKKHEFADYPPDQRLEWLFSSSDGHLPN----AFKVRE------------TRNISTYHKDFKKNANA----------YTGTVREA----LKLAFETCDKDLGDNALPNAKGVI----DRHAAMIAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-SNGSVTARQLSRAHCVDNADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-APQH-LFTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEDDE A0A2G5SBL7/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCISS-RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEIGNYPPDQRLEWLFSSSDGHLPN----AFKSRE------------TRNIAAYHKEFKKNPNT----------YTGTVREA----LKLAFETCDKDLGDNALPNAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVQRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LYTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEEDE A0A261AU81/12-355_388-450 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCLSS-RAFLFGVFDGHGGQQCGRHISTNLYPYLCASVLKKHEIGNYPPDQRLEWLFSSSDGHLPN----AFKSRE------------TRNISEYHKEFKKNANA----------YTGTVREA----LKLAFETCDRDLGDNALPNAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LYTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEEDE E3MGK7/12-355_388-451 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCLSS-RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEIGNYPPDQRLEWLFSSSDGHLPN----AFKSRE------------TRNISEYHKEFKKNANA----------YTGTVREA----LKLAFETCDRDLGDNALPNAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LYTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQVVPPGRARNYRDDITVIVIHFNETFLDGHEEDE A0A084W5U1/39-388_420-475 -----LSPYDVRTVNCILRANEHTQEF----FTGSVKSYDSNQLASNSPIEDSRSEGSCVHT-SGLLLGIFDGHGGPACSQVISKRLMRYIAASLVPPDDLRQHILNGAQS--FSFLSCHNDKA--RHCVFR---------LEFVSEIKELYEKSFHQFATE-LTNTT-LAG--FQMHQT----LENAFIRLDQDLSREAIEMP--------SLRTMSVAMSGAVALVAHIDGPHLHVASVGDCSAVLGTVT-DTGQWVAKKLTNEHNSDNVGEVRRLLSEHPATERDTVIRGERLLGQLAPLRAMGDFRYKWSREQLEQLVV----PQFGEQVIAPY-YHTPPYLSACPEITHHILTPRDKFLIIASDGLWDTMSAMQTVHLVGEHMYGKAFLQ--------------------------------RNASTHLIRNALGGTEYGV--EHSKLSHMLS-LPQDIVRLFRDDITITVVYFDSEYLRN----- W5JEK2/37-380_412-467 -GPPKLSPYD---VNNILRANEHTQEF----FGGSVKCYDSNQLASNSPIEDSRSEATCAHT-AGLLLGIFDGHGGPACSQVISKRLMRYIAASLVPPDDLRQHLLNGAQS--FSFLNCHNDK------------------LEFVSEIKELYEKSFLQFANE-LTNTT-LAG--FQMHQT----LENAFVRLDQDLSREAIEMP--------SLRTMSVAMSGAVALVAHIDGPHLHVASVGDCSAVLGTVT-DTGQWVAKKLTNEHNSDNVGEVRRLLSEHPATERDTVIRGERLLGQLAPLRAMGDFRYKWSREQLEQLVV----PQFGEQVIAPY-YLTPPYLSACPEITHHILTPRDKFLIIASDGLWDTMSAMQTVHLVGEHMYGKAFLQ--------------------------------RNAATHLIRNALGGTEYGI--EHSKLSHMLS-LPQDIVRLFRDDITITVVYFDSEYLRN----- A0A182Y3A0/35-395_428-483 -GPPKLSPYD---VNCILRANEHTQEF----FGGSVKSYDSNQLASNSPIEDSRSEASCVYT-SGLLVGIFDGHGGPACSQVISKRLMRYIAASLVPPDDLRQHMLGGAQS--FSFLSCHNDKARTRSHAFRNVLPTDTNGLEFVSEIKELYEKSFNQFANE-LTNTT-LAG--FQMHQT----LENAFIRLDQDLSREAIEMP--------SLRTMSVAMSGAVALVAHIDGPHLHVASVGDCSAVLGTVT-DTGQWVAKKLTNEHNSDNVGEVRRLLSEHPATERDTVIRGERLLGQLAPLRAMGDFRYKWSREQLEQLVV----PQFGEQVIAPY-YLTPPYLSACPEITHHILTPRDKFLIIASDGLWDTMSAMQTVHLVGEHMYGKAFL---------------------------------RNAATHLIRNALGGTEYGV--EHSKLSHMLS-LPQDIVRLFRDDITITVIYFDSEYLRN----- A8XF12/12-130_180-403_436-498 -RHNRSSRWN---ADAHLRAHERSANV----EDDAIMRVDTCQLAANNPIEDFYSAAKCISS-RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEHCPY----QKERLFPSPKNHIP------LKPYE-------KLKLLTRNIAAYHKEFKKNPNT----------YTGTVREA----LKLAFETCDKDLGDNALPNAKGVI----DRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVN-PNGSVTARQLSRAHCVDNADEVQRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVL-----EPLGHP-PPQH-LYTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTITQQ--------------------------------ENCATHIIRHALGGVSGGATKQYERLIDILQ-VPPGRARNYRDDITVIVIHFNETFLDGHEEDE B4IHN9/29-371_405-464 PQLPQLSPYD---VNLVLRENEFVYNF---PVDGVIRSYESNQLGSNWPCEDSRTEASLLHR-NGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMMQGADS--QSFLKCHNDN------------------VDFVSMIKPIYEASFLKYVNQ-LLETP-QR----DVSSE----LVNAFLQLDEEISQEALASN--------DVRTMNVALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDPETQQWQPKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVL----PMFGVQAMAPN-YYTPPYLTARPDVQQHKLGPNDKFLVIASDGLWDFLSPSEVVSLVGEHINSKKI----------------------------------QNAATHLIRHALGGTDYGI--EHSKISYYLT-LPRDVVRLYRDDITITVIYFNSEHIAKLHSD- A0A1W4V6G4/29-371_405-465 PQLPQLSPYD---VNLVLRENEFVYNF---PVDGVIRSYETNQLGSNSPCEDSRTEASFLHR-NGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGCSS--QSFLKCHNDN------------------VDFVSEIKPIYEASFLKYIKQ-LSETP-QR----DVASE----LENAFLQLDEGLSQEALASN--------DVRTMSVALSGAVACVVHLEGLQLHVASTGDCGAVLGTLDPQTQQWHPKKLNTEHNADNMSEVRRILAEHPKQERETVIRNGRLLSQLAPLRAFGDFRYKWSLDIMQQKVL----PMFGEQAMAPN-YYTPPYLTARPDVQHHELGPNDKFLVIASDGLWDFLSPSEVVSLVGEHINSKKI----------------------------------QNAATHLIRHALGATDYGI--EHSKISYYLT-LPKDVVRLYRDDITITVIYFNSEHVAQLHSEA B3NTS5/29-371_405-464 PQLPQLSPYD---VNLVLRENEFVYNF---PVEGVIRSYETNQLGSNSPCEDSRTEASLLHR-NGFICGIFDGHAGASCGQVVSKRLLRYVSAATLPRQVLREQMNQGADS--QSFLKCHNDN------------------VDFVSEIKPIYEASFLKYIKE-LKETP-QR----DVSSE----LVNAFLQLDAGLSQEALASS--------DVRTMSVALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWQPKKLNIEHNTENMSEVQRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSLDIMQQKVL----PMFGEQAMAPH-YYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLSPSEVVSLVGEHINSKKI----------------------------------QNAATHLIRHALGATDYGI--EHSKISYYLT-LPKDVVRLYRDDITITVIYFNSEHIAQLHSE- B4Q0T1/29-371_405-464 PQLPQLSPYD---VNLVLRENEFVYNF---PVDGVIRSYETNQLGSNSPCEDSRTEASLLHR-NGFICGIFDGHAGASCGQVVSKRLLRYVSAATLPRQVLREQMKQGADS--QSFLKCHNDN------------------VDFVSEIKPIYEASFLKYIKQ-LTETP-QR----DVSSE----LVDAFLQLDDGLSQEALASS--------DVRTMSVALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWQPKKLNIEHNAENMSEVRRILGEHPKEEQETVIRNGRLLSQLAPLRAFGDFRYKWSLDVMQQKVL----PMFGEQAMAPN-YYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLSPSEVVSLVGEHINSKKI----------------------------------QNAATHLIRHALGATDYGI--EHSKISYYLT-LPKDVVRLYRDDITITVIYFNSEHIAQLHTE- #=GC scorecons 02233354340005533764473434400002454735575589569495993454645544046575777999793595646756943964755744445344323342412463443733400000010110000000011124333337444634334303112101100114534400008439834594765369643411020000434544684796553567846357779649964998955403464436559534854583497497334994494378685699966949899698578995453443451000044574413555055799995639773584956596987696999973655445947956843643322000000000000000000000000000000004958786796888743253005634543483058343483688877657668544453311110 #=GC scorecons_70 _________________**__*_____________*___*__**_**_*_**____*_______*_*_********__*___**__*__*__*__*__________________*____*_______________________________*___*____________________________*__**___*_**___*__________________**_**_____***____*****_**__****______*______*___*___*__**_**___**__*__****_*****_*_*******_****_________________*__________*****_*_***__*_*___*****_*_*****_*_____*_**_**__*______________________________________*_******_****_______________*___*____*__******_**_*____________ #=GC scorecons_80 _________________*___*_____________*___*__**__*_*_**______________*_*__*****__*____*__*__*_____________________________*_______________________________*________________________________*__**___*_*____*___________________*_**______**____****__**__****_____________*___*___*__**_*____**__*__**_*__***__*_****_**_****____________________________*****___*_*__*_*___*_**__*_****________*_**__*_________________________________________*_***_**_***________________*___*____*__*****__*__*____________ #=GC scorecons_90 __________________________________________**__*_*_**___________________***_*__*_______*__*______________________________________________________________________________________________*__**___*______*___________________*__*_______*_______*__**__****_____________*___*___*__*__*____**__*___*_*__***__*_****_**__***_____________________________****___*______*___*_**__*_****________*__*__*_________________________________________*_*_*__*_***___________________________________________________ //