# STOCKHOLM 1.0 #=GF ID 3.60.21.10/FF/000090 #=GF DE Sphingomyelin phosphodiesterase #=GF AC 3.60.21.10/FF/000090 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 54.599 #=GS P17405/389-474 AC P17405 #=GS P17405/389-474 OS Homo sapiens #=GS P17405/389-474 DE Sphingomyelin phosphodiesterase #=GS P17405/389-474 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS P17405/389-474 DR GO; GO:0004767; GO:0005515; GO:0005615; GO:0005764; GO:0005768; GO:0005886; GO:0006684; GO:0006685; GO:0006687; GO:0007165; GO:0007399; GO:0008270; GO:0023021; GO:0035307; GO:0043202; GO:0043407; GO:0046513; GO:0061750; GO:0070062; #=GS P17405/389-474 DR EC; 3.1.4.12; #=GS E9LUE8/387-472 AC E9LUE8 #=GS E9LUE8/387-472 OS Homo sapiens #=GS E9LUE8/387-472 DE Sphingomyelin phosphodiesterase 1 isoform 6 #=GS E9LUE8/387-472 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS C3Z378/245-333 AC C3Z378 #=GS C3Z378/245-333 OS Branchiostoma floridae #=GS C3Z378/245-333 DE Uncharacterized protein #=GS C3Z378/245-333 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS H2LIK0/351-455 AC H2LIK0 #=GS H2LIK0/351-455 OS Oryzias latipes #=GS H2LIK0/351-455 DE Sphingomyelin phosphodiesterase #=GS H2LIK0/351-455 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS H9GJ07/274-380 AC H9GJ07 #=GS H9GJ07/274-380 OS Anolis carolinensis #=GS H9GJ07/274-380 DE Uncharacterized protein #=GS H9GJ07/274-380 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Lepidosauria; Squamata; Iguania; Dactyloidae; Anolis; Anolis carolinensis; #=GS F6YDD3/325-402 AC F6YDD3 #=GS F6YDD3/325-402 OS Xenopus tropicalis #=GS F6YDD3/325-402 DE Sphingomyelin phosphodiesterase #=GS F6YDD3/325-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS F7FD53/384-467 AC F7FD53 #=GS F7FD53/384-467 OS Monodelphis domestica #=GS F7FD53/384-467 DE Sphingomyelin phosphodiesterase #=GS F7FD53/384-467 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Didelphimorphia; Didelphidae; Didelphinae; Monodelphis; Monodelphis domestica; #=GS A0A091DPL1/376-460 AC A0A091DPL1 #=GS A0A091DPL1/376-460 OS Fukomys damarensis #=GS A0A091DPL1/376-460 DE Sphingomyelin phosphodiesterase #=GS A0A091DPL1/376-460 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys; Fukomys damarensis; #=GS A0A2K5JIB6/385-470 AC A0A2K5JIB6 #=GS A0A2K5JIB6/385-470 OS Colobus angolensis palliatus #=GS A0A2K5JIB6/385-470 DE Uncharacterized protein #=GS A0A2K5JIB6/385-470 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; #=GS G7NE16/325-410 AC G7NE16 #=GS G7NE16/325-410 OS Macaca mulatta #=GS G7NE16/325-410 DE Sphingomyelin phosphodiesterase #=GS G7NE16/325-410 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2R9AIC5/385-470 AC A0A2R9AIC5 #=GS A0A2R9AIC5/385-470 OS Pan paniscus #=GS A0A2R9AIC5/385-470 DE Uncharacterized protein #=GS A0A2R9AIC5/385-470 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS H2Q319/385-470 AC H2Q319 #=GS H2Q319/385-470 OS Pan troglodytes #=GS H2Q319/385-470 DE Sphingomyelin phosphodiesterase 1 #=GS H2Q319/385-470 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A3P9KPA0/351-455 AC A0A3P9KPA0 #=GS A0A3P9KPA0/351-455 OS Oryzias latipes #=GS A0A3P9KPA0/351-455 DE Sphingomyelin phosphodiesterase #=GS A0A3P9KPA0/351-455 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS A0A3P9JJQ5/351-455 AC A0A3P9JJQ5 #=GS A0A3P9JJQ5/351-455 OS Oryzias latipes #=GS A0A3P9JJQ5/351-455 DE Sphingomyelin phosphodiesterase #=GS A0A3P9JJQ5/351-455 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GF SQ 14 P17405/389-474 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- E9LUE8/387-472 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- C3Z378/245-333 ------------NLNWWLLLNTTDPAGQLQWLTQQLQQAEDKGEKVHIIGHIPPGIDCLSAWSWNYYRIIDRYESTVAAQFFGHTHRDHFELFYDMKNRTR-------- H2LIK0/351-455 ---VSLNMNFCARENFWLMVNSTDPANQLQWLVHILQDSEEKGEKVHIIGHIPPG-LCLGSWSWNYYHIINRYESTVTGQFFGHTHLDEFQMFYDEETMTRAVGVAFVA H9GJ07/274-380 LRLVSLNMNFCSEANFWLLINATDPAGQLQWLVGVLQRAEEIGEKVHIIGHIPPA-HCLRCWSWNYYRIINRFESTVAGQFFGHTHVDEFEMFYDEETLSRPVGIAFV- F6YDD3/325-402 --------------------NYTDPAGQLQWLVEVLQEAEEKGEKVHIIGHIPPG-LCLKSWSWNYYRIVNRYESTIAAQFFGHTHLDEFEMFYDEETL---------- F7FD53/384-467 -------------ENFWLLINSTDPAGQLQWLVRELQAAEDQGEKVHIIGHIPPG-HCLKSWSWNYYRIVGRYENTIAGQFFGHTHVDEFELFYDEET----------- A0A091DPL1/376-460 ------------RENFWLLINSTDPAGQLQWLIQELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYQIVSRYENTLAGQFFGHTHVDEFEIFYDEET----------- A0A2K5JIB6/385-470 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- G7NE16/325-410 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- A0A2R9AIC5/385-470 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- H2Q319/385-470 ------------RENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG-HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETL---------- A0A3P9KPA0/351-455 ---VSLNMNFCARENFWLMVNSTDPANQLQWLVHILQDSEEKGEKVHIIGHIPPG-LCLGSWSWNYYHIINRYESTVTGQFFGHTHLDEFQMFYDEETMTRAVGVAFVA A0A3P9JJQ5/351-455 ---VSLNMNFCARENFWLMVNSTDPANQLQWLVHILQDSEEKGEKVHIIGHIPPG-LCLGSWSWNYYHIINRYESTVTGQFFGHTHLDEFQMFYDEETMTRAVGVAFVA #=GC scorecons 0001111111104476775596999969999974499469759799999999997049946999999697498969666999999959796599977741101101110 #=GC scorecons_70 ______________*_**__*_***********__**_***_*************__**_**********_***_*_*_*******_****_******___________ #=GC scorecons_80 ______________*_**__*_****_******__**__*__*************__**__******_*__***_*___*******_***__******___________ #=GC scorecons_90 ____________________*_****_*****___**__*__*_**********___**__******_*__***_*___*******_*_*__***______________ //