# STOCKHOLM 1.0 #=GF ID 3.60.21.10/FF/000077 #=GF DE Sphingomyelin phosphodiesterase #=GF AC 3.60.21.10/FF/000077 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 84.803 #=GS Q54C16/183-492 AC Q54C16 #=GS Q54C16/183-492 OS Dictyostelium discoideum #=GS Q54C16/183-492 DE Sphingomyelin phosphodiesterase B #=GS Q54C16/183-492 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54C16/183-492 DR GO; GO:0004767; GO:0006685; GO:0046513; #=GS A0A139WJJ3/248-494 AC A0A139WJJ3 #=GS A0A139WJJ3/248-494 OS Tribolium castaneum #=GS A0A139WJJ3/248-494 DE Sphingomyelin phosphodiesterase-like Protein #=GS A0A139WJJ3/248-494 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS D6WVW3/219-517 AC D6WVW3 #=GS D6WVW3/219-517 OS Tribolium castaneum #=GS D6WVW3/219-517 DE Sphingomyelin phosphodiesterase #=GS D6WVW3/219-517 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS A0A139WDF2/219-517 AC A0A139WDF2 #=GS A0A139WDF2/219-517 OS Tribolium castaneum #=GS A0A139WDF2/219-517 DE Sphingomyelin phosphodiesterase #=GS A0A139WDF2/219-517 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7PZJ1/228-522 AC Q7PZJ1 #=GS Q7PZJ1/228-522 OS Anopheles gambiae #=GS Q7PZJ1/228-522 DE AGAP011940-PA #=GS Q7PZJ1/228-522 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS A8XCM9/154-281_313-463 AC A8XCM9 #=GS A8XCM9/154-281_313-463 OS Caenorhabditis briggsae #=GS A8XCM9/154-281_313-463 DE Sphingomyelin phosphodiesterase #=GS A8XCM9/154-281_313-463 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS F1A0M2/169-485 AC F1A0M2 #=GS F1A0M2/169-485 OS Dictyostelium purpureum #=GS F1A0M2/169-485 DE Sphingomyelin phosphodiesterase #=GS F1A0M2/169-485 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS H3ENB2/159-471 AC H3ENB2 #=GS H3ENB2/159-471 OS Pristionchus pacificus #=GS H3ENB2/159-471 DE Sphingomyelin phosphodiesterase #=GS H3ENB2/159-471 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A0A2G5V0C2/154-281_313-461 AC A0A2G5V0C2 #=GS A0A2G5V0C2/154-281_313-461 OS Caenorhabditis nigoni #=GS A0A2G5V0C2/154-281_313-461 DE Sphingomyelin phosphodiesterase #=GS A0A2G5V0C2/154-281_313-461 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A2K6VB97/253-547 AC A0A2K6VB97 #=GS A0A2K6VB97/253-547 OS Anopheles darlingi #=GS A0A2K6VB97/253-547 DE Sphingomyelin phosphodiesterase #=GS A0A2K6VB97/253-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Nyssorhynchus; darlingi group; Anopheles darlingi; #=GS A0A084WIG8/254-547 AC A0A084WIG8 #=GS A0A084WIG8/254-547 OS Anopheles sinensis #=GS A0A084WIG8/254-547 DE Uncharacterized protein #=GS A0A084WIG8/254-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS A0A182M166/253-547 AC A0A182M166 #=GS A0A182M166/253-547 OS Anopheles culicifacies #=GS A0A182M166/253-547 DE Sphingomyelin phosphodiesterase #=GS A0A182M166/253-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles culicifacies; #=GS A0A182VGX6/249-543 AC A0A182VGX6 #=GS A0A182VGX6/249-543 OS Anopheles merus #=GS A0A182VGX6/249-543 DE Sphingomyelin phosphodiesterase #=GS A0A182VGX6/249-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles merus; #=GS A0A182XJQ6/249-543 AC A0A182XJQ6 #=GS A0A182XJQ6/249-543 OS Anopheles quadriannulatus #=GS A0A182XJQ6/249-543 DE Uncharacterized protein #=GS A0A182XJQ6/249-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles quadriannulatus; #=GS A0A182U186/249-543 AC A0A182U186 #=GS A0A182U186/249-543 OS Anopheles melas #=GS A0A182U186/249-543 DE Uncharacterized protein #=GS A0A182U186/249-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles melas; #=GS A0A182Y9I9/253-547 AC A0A182Y9I9 #=GS A0A182Y9I9/253-547 OS Anopheles stephensi #=GS A0A182Y9I9/253-547 DE Uncharacterized protein #=GS A0A182Y9I9/253-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles stephensi; #=GS H3E4S9/216-503 AC H3E4S9 #=GS H3E4S9/216-503 OS Pristionchus pacificus #=GS H3E4S9/216-503 DE Sphingomyelin phosphodiesterase #=GS H3E4S9/216-503 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS W5JWZ2/772-1066 AC W5JWZ2 #=GS W5JWZ2/772-1066 OS Anopheles darlingi #=GS W5JWZ2/772-1066 DE Uncharacterized protein #=GS W5JWZ2/772-1066 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Nyssorhynchus; darlingi group; Anopheles darlingi; #=GF SQ 18 Q54C16/183-492 -TMKILHISDIHVDPVYESGMNADCGEPLCC-RAPNG--PGVGEKAAGEWGHY-LCDINMKMVESMFEFIDQEFGEDIDIVFWTGDNPPHDIWEQTYDSQINASQLVTNLVKKYFGSTAKVFPAIGNHESLPVNSFPLP------PGSSWIFNALSYDWSDWVNVDEQVANLQYGGYYTLPVQSGLRVISLNMNWC------NNGNLYLAEN-STDPANMLQWIVDTLQASEDIGEKVYLVGHIPPGIPDCIDSWSEQLLQIVNRYEDTILASFYGHTHRDEFSVYYTQSDENDPSSPMRASNVIYTTPSVTTYQHQNPSFRIFTVDS------------------------------ A0A139WJJ3/248-494 --------------------------------------------APAGKWGSYQKCDAPKVLIDNMLKSIAEEH-PDIDYVIWTGDLPPHDIWNQTKQSNLDIISETVEQMFEHFPN-TPIFPALGNHESIPAGSFAPPWVQDPDRSIAWLYTKVADHWRKWLPASAG-NTVLHGGFYSVLIRPGFRIISLNMNYC------HTLSWWLIVN-STDPAKELKWLVYELQEAENNGEKVHLIGHIPPGSSDCMKVWSRNFNKIIERYENTIQAQFYGHTHADEFEVLYDV-EES-----SRPINVAYL--------------------------------------------------- D6WVW3/219-517 -TFKVLHLSDTHYDPYYHEGSNADCSEPLCC-RLTNGL-ASTKEQAAGKWGDYRKCDTPKITVDNMLQHIQETH-PDIDYILWTGDLPPHDIWNQTREENLKIIKETVKQMSDMFPG-APIFPALGNHESAPVNSFPPPFIDNPDNSISWLYDELDVQWRKWLPSSVS-TTVRRGAFYSVLVRPGFRLISLNTNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFNNEKVHVIGHIPPGHSDCLKVWSRNYYAIVNRYEATITAQFFGHTHFDEFEVFYDH-KDL-----TRANNVAYVGPSVSPYYDLN---------------------------------------- A0A139WDF2/219-517 -TFKVLHLSDTHYDPYYHEGSNADCSEPLCC-RLTNGL-ASTKEQAAGKWGDYRKCDTPKITVDNMLQHIQETH-PDIDYILWTGDLPPHDIWNQTREENLKIIKETVKQMSDMFPG-APIFPALGNHESAPVNSFPPPFIDNPDNSISWLYDELDVQWRKWLPSSVS-TTVRRGAFYSVLVRPGFRLISLNTNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFNNEKVHVIGHIPPGHSDCLKVWSRNYYAIVNRYEATITAQFFGHTHFDEFEVFYDH-KDL-----TRANNVAYVGPSVSPYYDLN---------------------------------------- Q7PZJ1/228-522 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPKRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVTQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- A8XCM9/154-281_313-463 QNLNVLQLTDLHVDFEYKYPSEANCDDPVCC-RQS----VAEPKKASGYWGSVGKCDIPFWTVENMLSHINKTH--MIDMVLMTGDYINHVDWEYSIEEHLSVLRKLHRLVQNSFPT-TPIYWALGNHEGVPVNSF---------------------------------ESLLKRGSYATQIMDGLKLVSLNTGFC------EVTNFFLYLN-QSDPDSSMSWFVKELYESELKGEQVYVLAHIPPGDSECLEGWAFNYYRVIQRFESTIAAQFFGHDHLDYFTVFYED-MHNVS---SKPIGVGYAAPSVTTFEYQNPAYRVYEVDPYNK--------------------------- F1A0M2/169-485 -TMKILHLSDIHVDPIYEQGMNADCGEPLCC-RAVNG--PGKGSNAAGKWGHY-SCDVNLLMVGSMFEFIENEFGNEIDMVFWTGDNPPHDIWEQTFDGQLNSSLLVTNLVKKYFGS-SKIFPAIGNHESLPVNSFPLP------PGSSWLFNALASDWSDWINTDEQVKTLQWGGYYTLPVQNGIRVVSLNMNWC------NNGNLWMVENGTTDAAGMLQWVIETLQASEDIGEKVYLVGHIPPGIADCVDIWSEQFFQIVNRYEDTIIASFYGHTHRDEFEIYYTQ-DENNPNQ-TRPSSVVYVTPSVTTYQHQNPSFRIYTVDAQTGYVM--------------ESS------- H3ENB2/159-471 -VLKVLQITDIHIDFHYESGSEAECADPVCC-RGKNSRNWANPSVSAGFWGTIGKCDIPYRTMENMLKHISDTQ--HIDYIMVGGDIIDHYDWKYSWEETLEVLQNVSSLFKTHFPT-TPIYWALGNHEGVPVNSFAPHSVN---------------------------EQFWPVHLYD-------QLTEMNKPWIKEDGD-NSSRFFLYLN-QSDPDGTMTWFVDQLTKAELSGENVHILAHIPPGYYDCLEGWSRNYYRVIQRFSSIITGQFFGHVHYDYFTLFYED-MNDVS---SEPIGVAYVSPSASTFDYLNPGYRVYTLDAENTFKIIDHDNYYADLSFADENTEPEWKLL A0A2G5V0C2/154-281_313-461 QNLNVLQLTDLHVDFEYQYPSEANCDDPVCC-RQS----VAEPKKASGYWGSVGKCDTPFWTVENMLSHINKTH--MIDMVLMTGDYINHVDWEYSIEEHLSVLRKLHRLVQNSFPT-TPIYWALGNHEGVPVNSF---------------------------------ESLLKRGSYATQIMDGLKLISLNTGFC------EVTNFFLYLN-QSDPDSSMSWFVKELYDSELKGEQVYVLAHIPPGDSECLEGWAFNYYRVIQRFESTITAQFFGHDHLDYFTVFYED-MNNVT---SKPIGVGYAAPSVTTFEYQNPAYRVYEVDPY----------------------------- A0A2K6VB97/253-547 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTSPNGAAGKWGDYRKCDTPQRTVEHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLQETVKQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFANEKVHVIGHIPPGHSDCLKVWSRNYYKIISRYESTITAQFFGHTHFDEFEVFYDP-HDL-----GRATSIAYIGPSVTPYN------------------------------------------- A0A084WIG8/254-547 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPQRTVDHMLNHIADAH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVKQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSISWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPY-------------------------------------------- A0A182M166/253-547 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPQRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVKQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- A0A182VGX6/249-543 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPKRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVTQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- A0A182XJQ6/249-543 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPKRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVTQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- A0A182U186/249-543 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPKRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVTQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- A0A182Y9I9/253-547 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTTPNGAAGKWGDYRKCDTPQRTVDHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLKETVKQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFAGEKVHVIGHIPPGHSDCLKVWSRNYYKIVSRFESTITAQFFGHTHFDEFEVFYDP-HDL-----SRATSIAYIGPSVTPYN------------------------------------------- H3E4S9/216-503 -TLRVLQLTDIHVDFEYAEGSEAACQASVCCHRDKNASANLNITTPAGHWGSISKCDIPYRTLESMLRHINETE--ELDYIMVSGDLINHFDWEYSWEGHVGILRNLSSLFKSHFPS-TPIFWGVGNHEGVPVNSFPPHTID---------------------------QDFSPSQSYE-------ELTAMNEPWLKEKEERESSRFFLYLN-QSDPDGTMSWFVQELYQAELAGDFVHVLAHIPPGYSDCLEGWSRNYYRVVQRFSSVIRAQFFGHVHWDYFTVFYED-MHNVE---SEPVSVGYISPSATTFDYLNPAYRIYTVDRNDD--------------------------- W5JWZ2/772-1066 --FKVLHLSDTHFDPYYAEGSNADCNEPLCC-RLTNGR-PTSPNGAAGKWGDYRKCDTPQRTVEHMLNHIADTH-SDIDFIIWTGDLPPHDVWNQTKEENLKVLQETVKQMTEKFPG-IPIFPALGNHESAPVNSFPPPYVQQVDSSIAWLYDELDVQWRRWLPASVS-HTVRRGAFYSVLVRPGYRIISLNMNYC------NNKNWWLLLN-STDPATELQWFIYELQSAEFANEKVHVIGHIPPGHSDCLKVWSRNYYKIISRYESTITAQFFGHTHFDEFEVFYDP-HDL-----GRATSIAYIGPSVTPYN------------------------------------------- #=GC scorecons 0145675657474743733555757356577073353103334336794994536995734666597469456502589475479945594495563755746544544553439740568748799996598899444132112222233322322232232222220455345449433433636567794556000000653645846905698544659674695469447859766699999467975497577657749765795879799593949577953035410000566457595477665631121111111110000000000000000000000000000000 #=GC scorecons_70 ____**_*_*_*_*__*_____*_*__*_**_*____________***_**___***_*__***_**_**_______**_*__***___*__*__*_*__*_____________**___***_*******_*****_________________________________________*________*_****___*_________*__*__*__***___*_***_**__**__**_***_******_****__**_***_**_***_**_******_*_*_*_***____________*___*_*__**___*____________________________________________ #=GC scorecons_80 _____*___*_*_*__*_____*_*____**_*_____________**_**____**________**__*_______**_____**___*__*____*__*_____________*_____**_*_****__*****_________________________________________*____________**________________*__*___**_____*____*___*__**_**___*****__**___**_**__*__**___*_*_****_*_*_*_***________________*_*__**________________________________________________ #=GC scorecons_90 _______________________________________________*_**____**________*___*_______**_____**___*__*_____________________*_____*____****__**_**_________________________________________*_____________*________________*__*___**_____*____*___*___*_*____*****___*___*_________*____*___*_**_*_*_*___*__________________*____________________________________________________ //