# STOCKHOLM 1.0 #=GF ID 3.60.21.10/FF/000073 #=GF DE Serine/threonine-protein phosphatase with EF-hands #=GF AC 3.60.21.10/FF/000073 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 60.289 #=GS O14830/412-554 AC O14830 #=GS O14830/412-554 OS Homo sapiens #=GS O14830/412-554 DE Serine/threonine-protein phosphatase with EF-hands 2 #=GS O14830/412-554 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS O14830/412-554 DR GO; GO:0004722; GO:0006470; GO:0010801; GO:0030544; GO:0031435; GO:0043405; GO:0043409; GO:0043506; GO:0051879; #=GS O14830/412-554 DR EC; 3.1.3.16; #=GS O35385/424-575 AC O35385 #=GS O35385/424-575 OS Mus musculus #=GS O35385/424-575 DE Serine/threonine-protein phosphatase with EF-hands 2 #=GS O35385/424-575 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS O35385/424-575 DR GO; GO:0004722; GO:0010801; GO:0030544; GO:0031435; GO:0043409; GO:0051879; #=GS O35385/424-575 DR EC; 3.1.3.16; #=GS W5M8R5/375-545 AC W5M8R5 #=GS W5M8R5/375-545 OS Lepisosteus oculatus #=GS W5M8R5/375-545 DE Serine/threonine-protein phosphatase with EF-hands #=GS W5M8R5/375-545 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus; Lepisosteus oculatus; #=GS F6ZI83/392-542 AC F6ZI83 #=GS F6ZI83/392-542 OS Monodelphis domestica #=GS F6ZI83/392-542 DE Serine/threonine-protein phosphatase with EF-hands #=GS F6ZI83/392-542 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Didelphimorphia; Didelphidae; Didelphinae; Monodelphis; Monodelphis domestica; #=GS F1RYU8/401-550 AC F1RYU8 #=GS F1RYU8/401-550 OS Sus scrofa #=GS F1RYU8/401-550 DE Serine/threonine-protein phosphatase with EF-hands #=GS F1RYU8/401-550 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS E1B9Y5/409-571 AC E1B9Y5 #=GS E1B9Y5/409-571 OS Bos taurus #=GS E1B9Y5/409-571 DE Serine/threonine-protein phosphatase with EF-hands #=GS E1B9Y5/409-571 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS F6YKU1/512-668 AC F6YKU1 #=GS F6YKU1/512-668 OS Equus caballus #=GS F6YKU1/512-668 DE Serine/threonine-protein phosphatase #=GS F6YKU1/512-668 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Perissodactyla; Equidae; Equus; Equus; Equus caballus; #=GS M3W5Y3/405-553 AC M3W5Y3 #=GS M3W5Y3/405-553 OS Felis catus #=GS M3W5Y3/405-553 DE Serine/threonine-protein phosphatase with EF-hands #=GS M3W5Y3/405-553 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus; #=GS A0A2K5QW81/413-554 AC A0A2K5QW81 #=GS A0A2K5QW81/413-554 OS Cebus capucinus imitator #=GS A0A2K5QW81/413-554 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A2K5QW81/413-554 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Cebinae; Cebus; Cebus capucinus; Cebus capucinus imitator; #=GS W5Q335/408-571 AC W5Q335 #=GS W5Q335/408-571 OS Ovis aries #=GS W5Q335/408-571 DE Serine/threonine-protein phosphatase with EF-hands #=GS W5Q335/408-571 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries; #=GS A0A2K5MYS4/411-554 AC A0A2K5MYS4 #=GS A0A2K5MYS4/411-554 OS Cercocebus atys #=GS A0A2K5MYS4/411-554 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A2K5MYS4/411-554 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Cercocebus; Cercocebus atys; #=GS A0A2K5E1Q5/411-553 AC A0A2K5E1Q5 #=GS A0A2K5E1Q5/411-553 OS Aotus nancymaae #=GS A0A2K5E1Q5/411-553 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A2K5E1Q5/411-553 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Aotidae; Aotus; Aotus nancymaae; #=GS D3ZN69/420-572 AC D3ZN69 #=GS D3ZN69/420-572 OS Rattus norvegicus #=GS D3ZN69/420-572 DE Serine/threonine-protein phosphatase with EF-hands #=GS D3ZN69/420-572 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS A0A452FXQ8/398-561 AC A0A452FXQ8 #=GS A0A452FXQ8/398-561 OS Capra hircus #=GS A0A452FXQ8/398-561 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A452FXQ8/398-561 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS F7I4P5/413-554 AC F7I4P5 #=GS F7I4P5/413-554 OS Callithrix jacchus #=GS F7I4P5/413-554 DE Serine/threonine-protein phosphatase with EF-hands #=GS F7I4P5/413-554 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2K5JGV0/392-535 AC A0A2K5JGV0 #=GS A0A2K5JGV0/392-535 OS Colobus angolensis palliatus #=GS A0A2K5JGV0/392-535 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A2K5JGV0/392-535 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; #=GS H2QPP9/414-554 AC H2QPP9 #=GS H2QPP9/414-554 OS Pan troglodytes #=GS H2QPP9/414-554 DE Serine/threonine-protein phosphatase with EF-hands #=GS H2QPP9/414-554 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2K5ZRR9/395-538 AC A0A2K5ZRR9 #=GS A0A2K5ZRR9/395-538 OS Mandrillus leucophaeus #=GS A0A2K5ZRR9/395-538 DE Serine/threonine-protein phosphatase with EF-hands #=GS A0A2K5ZRR9/395-538 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Mandrillus; Mandrillus leucophaeus; #=GS G7P561/410-557 AC G7P561 #=GS G7P561/410-557 OS Macaca fascicularis #=GS G7P561/410-557 DE Serine/threonine-protein phosphatase with EF-hands #=GS G7P561/410-557 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GF SQ 19 O14830/412-554 -----------------------------EKEEPSRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQR--ISRV------------------- O35385/424-575 -------------------------------------DADCVADGGGVLEPTPEEWKQVVDILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHRLTMRQR--ISRVEESALRALRQKLFAHSS-- W5M8R5/375-545 HSISQKVWRSVEEELEKCRRQVGFSELF-DDSKHSLSPSDSDSESFEICESDDMEWKQIVDILWSDPMAHEGCVLNHVRGGGCYFGPDVTEAVLARHNLQLLIRSHECKQEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVRLGPDLTPHIVQYQASRTTRKLTMRQR--VSRI------------------- F6ZI83/392-542 --------------------QVSFPEFK-DKEEPSLCPSKAEPDPCDLQDVSHEEWKQVVDILWSDPMAQEGCKANSVRGGGCYFGPNVTQQMLQRHSLLFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPDLIPHIVQYQTNKATHTLTMQQR--ISRV------------------- F1RYU8/401-550 ----------------------GFPVIK-EKEESSPSASEADLDADEWPEPTQEEWRQVVDILWSDPMPQEGCRANTVRGGGCYFGPNVTEWLLQKYNLQFLIRSHECKPEGYEFCHGRKVLTIFSASNYYAVGSNRGAY-------------FQANKATHTLTMRQR--ISRVEESALR-----FFAHSSDL E1B9Y5/409-571 -------------------------AIK-EKEEPSSSESEVDSDAEEQPQPTPEEWRQVVDILWSDPMAQEGCRANTVRGGGCYFGPNVTERLLQKYHLQFLIRSHECKPEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVKLGPELTPHIMQFQANKATHTLTMRQR--ISRVEESALRALREKLFAHSS-- F6YKU1/512-668 ---------------ERCRQQAGFPVIKEKKEEPLLFSSEADSEAGELLQPTQEEWRQVVDILWSDPMAQEGCKANTVRGGGCYFGPNVTEQLLQKYNLQFLIRSHECKPEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHMLTMRQR--ISRV------------------- M3W5Y3/405-553 ----------------------GLPVSR-GEEEASPCTPEADSGAEEPLEPTQEEWRQVVDILWSDPMAQEGCKANTVRGGGCYFGPNVTERLLQKYNLQFLIRSHECKPEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVKLGPALTPYIVQYQANKVTHMLTMRQR--ISRV------------------- A0A2K5QW81/413-554 ------------------------------KEEPSCSASETDSDTGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTEQLLQKYKLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQR--ISRV------------------- W5Q335/408-571 ------------------------PAIK-EKEEPSSSESEVDSDAEEPPQPTPEEWRQVVDILWSDPMAQEGCRANTVRGGGCYFGPNVTEQLLQKYNLQFLIRSHECKPEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVKLGPDLTPHIMQFQANKATHMLTMRQR--ISRVEESALRALREKLFAHSS-- A0A2K5MYS4/411-554 ----------------------G------QKEEASRSAAEADSEAGELQKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTNTLTMRQR--ISRV------------------- A0A2K5E1Q5/411-553 -----------------------------EKEEPSCSASETDSDTEELQKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTEQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHTLTMRQR--ISRV------------------- D3ZN69/420-572 ------------------------------------PLADCDADAGGMLKPTPEEWKQVVDILWSDPMAQEGCKANTVRGGGCYFGPDVTEQLMEKYKLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHRLTMRQR--ISRVEESALRALRQKLFAHSS-- A0A452FXQ8/398-561 ------------------------PAIK-EKEEPSSSESEVDSDAEEPPQPTPEEWRQVVDILWSDPMAQEGCRANTVRGGGCYFGPNVTEQLLQKYNLQFLIRSHECKPEGYEFCHSRKVLTIFSASNYYEVGSNRGAYVKLGPDLTPHIMQFQANKATHTLTMRQR--ISRVEESALRALREKLFAHSS-- F7I4P5/413-554 ------------------------------KEEPSGSASETDSDTGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTEQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQR--ISRV------------------- A0A2K5JGV0/392-535 ----------------------G------QKEEPSYSASEADSEAGELQKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQTNKVTNTLTMRQR--ISRV------------------- H2QPP9/414-554 -------------------------------EEPFRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNLQFVIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQR--ISRV------------------- A0A2K5ZRR9/395-538 ----------------------G------QKEEASRSASEADSEAGELQKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNLRFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTNTLTMRQR--ISRV------------------- G7P561/410-557 ---------------------TG------QKEEPSRSASEADSEAGELQKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTNTLTMRQRQDFSMME------------------ #=GC scorecons 0000000000000000000000101011024554525467476654743577579979899999999888999679679999999996996577677687789999999799999995999999999999979999999976777477777677987859659998990079871111110000001111100 #=GC scorecons_70 ______________________________________**_*_*__*___**_**************************************_*************************_***************************_************_**_******__****___________________ #=GC scorecons_80 _________________________________________*____*___*__********************_**_**********_**__**_**_*******************_***********************_***_*_***_******_*__******__****___________________ #=GC scorecons_90 ______________________________________________________**_**********_*****__*__*********_**________*__********_*******_*************_********______________*__*_*__******___**____________________ //