# STOCKHOLM 1.0
#=GF ID 3.40.50.720/FF/000644
#=GF DE NAD dependent epimerase/dehydratase family, putative
#=GF AC 3.40.50.720/FF/000644
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 84.591
#=GS O94563/1-334        AC O94563
#=GS O94563/1-334        OS Schizosaccharomyces pombe 972h-
#=GS O94563/1-334        DE Putative uncharacterized oxidoreductase C1773.04
#=GS O94563/1-334        DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS O94563/1-334        DR GO; GO:0043892; GO:0061727; GO:0140041; 
#=GS Q581S7/121-479      AC Q581S7
#=GS Q581S7/121-479      OS Trypanosoma brucei brucei TREU927
#=GS Q581S7/121-479      DE Uncharacterized protein
#=GS Q581S7/121-479      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q581S7/121-479      DR GO; GO:0005739; GO:0005741; GO:0010608; 
#=GS Q4Q2M5/106-466      AC Q4Q2M5
#=GS Q4Q2M5/106-466      OS Leishmania major
#=GS Q4Q2M5/106-466      DE Uncharacterized protein
#=GS Q4Q2M5/106-466      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4Q2M5/106-466      DR GO; GO:0005739; GO:0005741; 
#=GS A0A0D1BUI1/3-286    AC A0A0D1BUI1
#=GS A0A0D1BUI1/3-286    OS Ustilago maydis 521
#=GS A0A0D1BUI1/3-286    DE Chromosome 23, whole genome shotgun sequence
#=GS A0A0D1BUI1/3-286    DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago; Ustilago maydis; 
#=GS A0A3P3Z526/106-466  AC A0A3P3Z526
#=GS A0A3P3Z526/106-466  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3Z526/106-466  DE NADH(P)-binding/NAD_dependent_epimerase/dehydrata se_family/3-beta_hydroxysteroid_dehydrogenase/isomerase_fam ily
#=GS A0A3P3Z526/106-466  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS A0A1G4I6Y8/121-479  AC A0A1G4I6Y8
#=GS A0A1G4I6Y8/121-479  OS Trypanosoma equiperdum
#=GS A0A1G4I6Y8/121-479  DE NAD dependent epimerase/dehydratase family, putative
#=GS A0A1G4I6Y8/121-479  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS A0A088RPM8/107-466  AC A0A088RPM8
#=GS A0A088RPM8/107-466  OS Leishmania panamensis
#=GS A0A088RPM8/107-466  DE Uncharacterized protein
#=GS A0A088RPM8/107-466  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9B5A8/106-465      AC E9B5A8
#=GS E9B5A8/106-465      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9B5A8/106-465      DE Uncharacterized protein
#=GS E9B5A8/106-465      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4IAN1/107-466      AC A4IAN1
#=GS A4IAN1/107-466      OS Leishmania infantum
#=GS A4IAN1/107-466      DE NmrA-like_family/NADH(P)-binding/NAD_dependent_ep imerase/dehydratase_family/3-beta_hydroxysteroid_dehydrogen ase/isomerase_family_-_putative
#=GS A4IAN1/107-466      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A3S7X885/107-466  AC A0A3S7X885
#=GS A0A3S7X885/107-466  OS Leishmania donovani
#=GS A0A3S7X885/107-466  DE NmrA-like family/NADH(P)-binding/NAD dependent epimerase/dehydratase family/3-beta hydroxysteroid dehydrogenase/isomerase family, putative
#=GS A0A3S7X885/107-466  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A1E1IUN7/106-466  AC A0A1E1IUN7
#=GS A0A1E1IUN7/106-466  OS Leishmania guyanensis
#=GS A0A1E1IUN7/106-466  DE Uncharacterized protein
#=GS A0A1E1IUN7/106-466  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS A4HB38/106-466      AC A4HB38
#=GS A4HB38/106-466      OS Leishmania braziliensis
#=GS A4HB38/106-466      DE Contig, possible fusion of chromosomes 20 and 34
#=GS A4HB38/106-466      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS E9BR95/107-466      AC E9BR95
#=GS E9BR95/107-466      OS Leishmania donovani BPK282A1
#=GS E9BR95/107-466      DE Uncharacterized protein
#=GS E9BR95/107-466      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GF SQ 13
O94563/1-334                -------MSELVLITGITGFVASHSAEALLSQGYRVRGTYRFQ---EKLDGLLKNRPEWEKKVEFVQVPDCRAPNAYVEAAKGVDYVIHAATEVHSNLEPPRKDPHELLHIAIQGCENALIAAAQEPKVKRFVYISSEAALKGPVNYFGDGHVFTEKDWNPKTLREAEESDDELL-NYTVCKKLGERAMHAFVARNTPRFQAIALNPPLILGPVFHLQSVDNLNFSTWFFWQLIKGRYEVAPESKFF--------NYVDVRDLAEAQVKALTAKTDKD-RFV-ISGGAFKNDDIVNVALKYFPQFKDKIAKPNGETSPCNYEV--DASLSIK-------------------ELGLTYRPAEETFKDATESLYKLAG--------------
Q581S7/121-479              ERAKSLRSKTVVLIVGGVGYVSSHVVNKALEAGYSVRITGSGALTPQQQAALSSVGRDHEQRLSIFE-ADMTNTNSLRDALRGCKYVIHCGCPVSS---TD-KDTVEFHLSAVQALFNA-IRQAGKSTVKRVVIHGAASSVFHVTDPEPPSGAFDESCWN-----SVATNDTDPI-PY--ARIYFEK--EAWRLKQMLGVELVVILPSITIGPSRTEEVSDAM-----------KRIQHLATASSYFPYAPNLHWNFVDVRDVAEAHVRALECQEVKDQRVI-VSGGCFSFAEIGKLIRNEYPHLTPPTRTANTLMTLIIGAT--HSQVSIRFLWRTLGVRKCLDTRKATTELGMKFTPMQETLRASIEQMISAGELPPADGSVNARSV-
Q4Q2M5/106-466              -KARAAKMKIHVLVIGESGYLASHVVAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADVTNSNSLRDAIRGCRYIIHCGCSSAS---PQAKDLVVLYTKAIRALFDG-IRLSGKSTVKRVVLTGAASSIVHITECDPPSGLFDESNWN-----SVATPEDDPL-PF--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRALEVAEARDQRII-ISNECVSLPELCRMMKQLCPQLTPPTHTAWTFVTLGIATVVLWNSVNLRFLWRSLGVRKRLDNRRAKEQLGVSFTPMQQTLRDCLDQMSRSAKA-TADAEAAAAAQH
A0A0D1BUI1/3-286            ----GTSRNVRVLVTGANGFVGSHIVSLLLSRGYVVNATVRRQTASEKLIATFAC-----DRLHVFVIPDLTSEQALDEAIRGCKYVVHVASTVPS---KEQASGIDI-DSAISSIESV-MNSAVAHASEKVVLTSSMS-----THLDVKAPILNESTWY-----TPDRSSTKLMVQYMSSKTLVER--RAWELSSTLKLPLTTVAPVYIGGPTIIHEQDPKSS----------VSNQDLLRCIEDESRSRIP--GWIDVRTVAHLHLHAIEDHSLNGRRILACTHNRGVVPMDCSLMNSLLAK---------------------DSAALIDF---------------------------DRTKRDLLEQ--------------------
A0A3P3Z526/106-466          -KARAAKMKIHVLVIGESGYLASHVIAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADITNSNTLRDAIRGCRYIVHCGCSSAS---PQAKDLVTFYTKAIRALFDG-IRLSGKSTVKRVVLTGSASSIVHITECDPPSGLFDENNWN-----SVATPEDDPL-PY--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRAMEVAEVRDQRII-ISNECVSLPELCRTMKQLCPQLTPPTHTAWTVVTLGIATLVLWNSVNLRFLWRSLGVRKRLNNRRAKEQLGITFTPMQQTLRDCLEQMTRSAKV-TADAEAAAAAQR
A0A1G4I6Y8/121-479          ERAKSLRSKTVVLIVGGVGYVSSHVVNKALEAGYSVRITGSGALTPQQQAALSSVGRDHEQRLSIFE-ADMTNTNSLRDALRGCKYVIHCGCPVSS---TD-KDTVEFHLSAVQALFNA-IRQAGKSTVKRVVIHGAASSVFHVTDPEPPSGAFDESCWN-----SVATNDTDPI-PY--ARIYFEK--EAWRLKQMLGVELVVILPSITIGPSRTEEVSDAM-----------KRIQHLATASSYFPYAPNLHWNFVDVRDVAEAHVRALECQEVKDQRVI-VSGGCFSFAEIGKLIRNEYPHLTPPTRTANTLMTLIIGAT--HSQVSIRFLWRTLGVRKCLDTRKATTELGMKFTPMQETLRASIEQMISAGELPPADGSVNARSV-
A0A088RPM8/107-466          --ARAAKMKIHVLVIGESGYLASHVIAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADITNSNTLRDAIRGCRYIVHCGCSSAS---PQAKDLVTFYTKAIRALFDG-IRLSGKSTVKRVVLTGSASSIVHITECDPPSGLFDENNWN-----NVATPEDDPL-PY--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRAMEVAEVRDQRII-ISNECVSLPELCRTMKQLCPQLTPPTHTAWTVVTLGIATLVLWNSVNLRFLWRSLGVRKRLNNRRAKEQLGITFTPMQQTLRDCLEQMTRSAKV-TADAEAAAAAQR
E9B5A8/106-465              -KARAAKMKIHVLVIGESGYLASHVVAKLLDAGYSVRMTVPDVARQQKQIDLYGASRDVAQRLTILQ-ADVTNSNSLRDAIRGCRYIIHCGCSSAS---PQAKDLVALYTKAIRALFDG-IRLSGKSTVKRVVLTGAASSIVHITECDPPSGLFDESNWN-----SVATPEDDPL-PF--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRALEVVEVRDQRII-ISNECVSLPELCRMMKQLCPHLTPPTHTAWTFVTLGIATVVLWNSVNLRFLWRSLGVRKRLNNRRAKELLGVSFTPMQQTLRDCLDQMTRSAKA-TADAEAAAAAQ-
A4IAN1/107-466              --ARAAKMKIHVLVVGESGYLASHVVAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADVTNSNSLRDAIRGCRYIIHCGCSSAS---PQAKDLVALYTKAIRALFDG-IRLSGKSTVKRVVLTGAASSIVHITECDPPSGLFDESNWN-----SVATPEDDPL-PF--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRALEVAEVRDQRII-ISNECVSLPELCRMMKQLCPQLTPPTHTAWTFVTLGIATVVLWNSVNLRFLWRSLGVRKRLDNRRAKEQLGVSFTPMQQTLRDCLDQMSRSAKA-NADAEAAAAAQR
A0A3S7X885/107-466          --ARAAKMKIHVLVVGESGYLASHVVAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADVTNSNSLRDAIRGCRYIIHCGCSSAS---PQAKDLVALYTKAIRALFDG-IRLSGKSTVKRVVLTGAASSIVHITECDPPSGLFDESNWN-----SVATPEDDPL-PF--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRALEVAEVRDQRII-ISNECVSLPELCRMMKQLCPQLTPPTHTAWTFVTLGIATVVLWNSVNLRFLWRSLGVRKRLDNRRAKEQLGVSFTPMQQTLRDCLDQMSRSAKA-NADAEAAAAAQR
A0A1E1IUN7/106-466          -KARAAKMKIHVLVIGESGYLASHVIAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADITNSNTLRDAIRGCRYIVHCGCSSAS---PQAKDLVTFYTKAIRALFDG-IRLSGKSTVKRVVLTGSASSIVHITECDPPSGLFDENNWN-----SVATPEDDPL-PY--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRAMEVAEVRDQRII-ISNECVSLPELCRTMKQLCPQLTPPTHTAWTVVTLGIATLVLWNSVNLRFLWRSLGVRKRLNNRRAKEQLGITFTPMQQTLRDCLEQMSRSAKV-TADAEAATAAQR
A4HB38/106-466              -KARAAKMKIHVLVIGESGYLASHVIAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADITNSNTLRDAIRGCRYIVHCGCSSAS---PQAKDLVTFYTKAIRALFDG-IRLSGKSTVKRVVLTGSASSIVHITECDPPSGLFDENNWN-----SVATPEDDPL-PY--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRAMEVAEVRDQRII-ISNECVSLPELCRTMKQLCPQLTPPTHTAWTVVTLGIATLVLWNSVNLRFLWRSLGVRKRLNNRRAKEQLGITFTPMQQTLRDCLEQMTRSAKV-TADAEAAAAAQR
E9BR95/107-466              --ARAAKMKIHVLVVGESGYLASHVVAKLLDAGYSVRMTVPDAARQQKQIDLYGASRDVAQRLTILQ-ADVTNSNSLRDAIRGCRYIIHCGCSSAS---PQAKDLVALYTKAIRALFDG-IRLSGKSTVKRVVLTGAASSIVHITECDPPSGLFDESNWN-----SVATPEDDPL-PF--AKLVFER--EAWRLRQMMGVELVVLLPSISIGPSLTDETSEAM-----------VTIEGLANSSKYFPFCPNLSWNFVDVRDVADAHVRALEVAEVRDQRII-ISNECVSLPELCRMMKQLCPQLTPPTHTAWTFVTLGIATVVLWNSVNLRFLWRSLGVRKRLDNRRAKEQLGVSFTPMQQTLRDCLDQMSRSAKA-NADAEAAAAAQR
#=GC scorecons              013233345439975934976599564469559949649443533367544644434523577465506946546564795796597795654549000542663545334974554540753645556777955664744243743554544759549600000555545565605700573449700596465555555665649554599545474555500000000000444447644655543344423667999679567769663354574966057455444554444544447644444344242344242331135554656333233333232232322355335454559576357642334310233222232221
#=GC scorecons_70           ___________***_*__***_**____**__**_**_*_______**___*_________**______*_*__*_*_**_***_****______*______**_______**_______*_______*****_____*_____*________*_*__**______________*__*___*___**___**_*_______*____*____**____*_____________________**__*___________*_*******_*****_*_____*_*_*__*_________________*___________________________*_______________________________*_**__**____________________
#=GC scorecons_80           ___________**__*__**__**_____*__**_*__*________*_____________**______*_________*_**__*__*______*_______________**_______*_________*_*_____*______________*_*__*__________________*___*___**___*_______________*____**____*_____________________*_________________****_**__**_*_________*__________________________________________________________________________________*_*___*_____________________
#=GC scorecons_90           ___________**__*__*___**_____*__**_*__*______________________________*_________*__*__*__*______*_______________*____________________*______________________*__*__________________________*____*_______________*____**_____________________________________________***__*_____*_________*__________________________________________________________________________________*___________________________
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