# STOCKHOLM 1.0
#=GF ID 3.40.50.720/FF/000554
#=GF DE Homoserine dehydrogenase
#=GF AC 3.40.50.720/FF/000554
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 96.823
#=GS Q58997/3-165_312-328      AC Q58997
#=GS Q58997/3-165_312-328      OS Methanocaldococcus jannaschii DSM 2661
#=GS Q58997/3-165_312-328      DE Homoserine dehydrogenase
#=GS Q58997/3-165_312-328      DR ORG; Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; Methanocaldococcus jannaschii; 
#=GS Q58997/3-165_312-328      DR EC; 1.1.1.3; 
#=GS Q5JIS3/6-166_311-327      AC Q5JIS3
#=GS Q5JIS3/6-166_311-327      OS Thermococcus kodakarensis KOD1
#=GS Q5JIS3/6-166_311-327      DE Homoserine dehydrogenase
#=GS Q5JIS3/6-166_311-327      DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus kodakarensis; 
#=GS B1L7E1/4-165_309-325      AC B1L7E1
#=GS B1L7E1/4-165_309-325      OS Candidatus Korarchaeum cryptofilum OPF8
#=GS B1L7E1/4-165_309-325      DE Homoserine dehydrogenase
#=GS B1L7E1/4-165_309-325      DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; 
#=GS A9A4A3/3-166_311-327      AC A9A4A3
#=GS A9A4A3/3-166_311-327      OS Nitrosopumilus maritimus SCM1
#=GS A9A4A3/3-166_311-327      DE Homoserine dehydrogenase
#=GS A9A4A3/3-166_311-327      DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Nitrosopumilus maritimus; 
#=GS Q8TMT0/8-152_311-325      AC Q8TMT0
#=GS Q8TMT0/8-152_311-325      OS Methanosarcina acetivorans C2A
#=GS Q8TMT0/8-152_311-325      DE Homoserine dehydrogenase
#=GS Q8TMT0/8-152_311-325      DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina acetivorans; 
#=GS Q7LXP8/5-145_291-307      AC Q7LXP8
#=GS Q7LXP8/5-145_291-307      OS Saccharolobus solfataricus P2
#=GS Q7LXP8/5-145_291-307      DE Homoserine dehydrogenase (ThrA/hom)
#=GS Q7LXP8/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS Q8ZUB0/4-137_284-298      AC Q8ZUB0
#=GS Q8ZUB0/4-137_284-298      OS Pyrobaculum aerophilum str. IM2
#=GS Q8ZUB0/4-137_284-298      DE Homoserine dehydrogenase
#=GS Q8ZUB0/4-137_284-298      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; Pyrobaculum aerophilum; 
#=GS A0A087S1Z6/3-166_311-327  AC A0A087S1Z6
#=GS A0A087S1Z6/3-166_311-327  OS Marine Group I thaumarchaeote SCGC AAA799-P11
#=GS A0A087S1Z6/3-166_311-327  DE Homoserine dehydrogenase protein
#=GS A0A087S1Z6/3-166_311-327  DR ORG; Archaea; Thaumarchaeota; Marine Group I thaumarchaeote SCGC AAA799-P11; 
#=GS S2E4L0/3-166_311-327      AC S2E4L0
#=GS S2E4L0/3-166_311-327      OS Candidatus Nitrosarchaeum limnium BG20
#=GS S2E4L0/3-166_311-327      DE Homoserine dehydrogenase
#=GS S2E4L0/3-166_311-327      DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosarchaeum; Candidatus Nitrosarchaeum limnium; 
#=GS C3MW08/5-145_291-307      AC C3MW08
#=GS C3MW08/5-145_291-307      OS Sulfolobus islandicus M.14.25
#=GS C3MW08/5-145_291-307      DE Homoserine dehydrogenase
#=GS C3MW08/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; 
#=GS A0A0E3KX87/7-152_311-317  AC A0A0E3KX87
#=GS A0A0E3KX87/7-152_311-317  OS Methanosarcina sp. WH1
#=GS A0A0E3KX87/7-152_311-317  DE Homoserine dehydrogenase
#=GS A0A0E3KX87/7-152_311-317  DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WH1; 
#=GS A0A0E3NKK9/7-152_311-317  AC A0A0E3NKK9
#=GS A0A0E3NKK9/7-152_311-317  OS Methanosarcina sp. WWM596
#=GS A0A0E3NKK9/7-152_311-317  DE Homoserine dehydrogenase
#=GS A0A0E3NKK9/7-152_311-317  DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WWM596; 
#=GS A0A0E3S273/8-152_311-326  AC A0A0E3S273
#=GS A0A0E3S273/8-152_311-326  OS Methanosarcina lacustris Z-7289
#=GS A0A0E3S273/8-152_311-326  DE Homoserine dehydrogenase
#=GS A0A0E3S273/8-152_311-326  DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina lacustris; 
#=GS A0A429G5G5/4-165_309-325  AC A0A429G5G5
#=GS A0A429G5G5/4-165_309-325  OS Candidatus Korarchaeum cryptofilum
#=GS A0A429G5G5/4-165_309-325  DE Homoserine dehydrogenase
#=GS A0A429G5G5/4-165_309-325  DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; 
#=GS Q9UX47/5-145_291-307      AC Q9UX47
#=GS Q9UX47/5-145_291-307      OS Saccharolobus solfataricus
#=GS Q9UX47/5-145_291-307      DE Homoserine dehydrogenase
#=GS Q9UX47/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS D0KT64/5-145_291-307      AC D0KT64
#=GS D0KT64/5-145_291-307      OS Saccharolobus solfataricus 98/2
#=GS D0KT64/5-145_291-307      DE Homoserine dehydrogenase
#=GS D0KT64/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS C4KHL4/5-145_291-307      AC C4KHL4
#=GS C4KHL4/5-145_291-307      OS Sulfolobus islandicus M.16.4
#=GS C4KHL4/5-145_291-307      DE Homoserine dehydrogenase
#=GS C4KHL4/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; 
#=GS C3N651/5-145_291-307      AC C3N651
#=GS C3N651/5-145_291-307      OS Sulfolobus islandicus M.16.27
#=GS C3N651/5-145_291-307      DE Homoserine dehydrogenase
#=GS C3N651/5-145_291-307      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; 
#=GF SQ 18
Q58997/3-165_312-328              IIIVGFGAIGKGIAKVLYDKKDYLKKNYE-EFKVVAITDSSGAAIDEDGLDLLKAIEV-KEKTGKIKNYPEKGR--EMSSIDVIKEVDADVVVEVTPSNLETGDPAKTHILESFKNKKHVVTANKGPLALCYKELIEEAKKHGVIFRHEASVGGAMPIINLAKETLARGAGPIETASAILSDLI
Q5JIS3/6-166_311-327              VSLIGFGNVGRATAGVLLEKSRLFEERYGVRISVVSISDTSGTVWLPEGIDLREALLV-KENFGRLSAWTNDYEVYELTPEEIVGEVDSEIVVDVT-----NDKEAWTWHLRALKEGKGIVTSNKPPLAYHYREILNEAEKRELPYLFEATVMAGTPIVGLLRENLLAGAGLKETASGVISDVI
B1L7E1/4-165_309-325              -ILMGLGVVGRSFLRMLIEKSPELRLKYGLNPTLVAVADSTSAVQDERGLDPKEILDM-KVKKGSLSGHA-CEV--GMRGVELIRGVEAEVLIDVTPSNFKTGEPSLSYIKAALNTGKHVITASKGPFALEMPALIEMFQESGLRLLFSGTVGGGVPFVRFVRKCLIKGAGGDETAMALIRDLV
A9A4A3/3-166_311-327              IILCGFGVVGQSLVKLFESRAEDLYAKYGLKPRVVGVFDSKGSAMDSSGLELNKLIEV-KKKFGTVKNYADTKN--TMSGIDMLKNVEADVLIETTASNYKDAEPGMTHIITAMKKGMHVISVNKGPLALAFPSLMELATYNRVMFKFSGTVGGGTPILDYAKNSLSRGAGGMETASSILRDLL
Q8TMT0/8-152_311-325              --ILGFGAIGQGVAEVLLMKKEYLK-SIGLEVLVVAVVDSKGATVDPAGVDLADCLAR-KRTKGTVAIE-------KLTGVEVIRSVSHELVIETTPTNIVTGGAGLQNMLAAFETGKDVVTSNKGPLTLKYRELTKAAKAAGSNFRFEATVGGSM------------GAGPIETASAILSDF-
Q7LXP8/5-145_291-307              --LIGYGNVGKAFRRLLHEKKDNYPILQGVEIA---------------GIITRQGLMV-----GDKENFS-PDK--QLTVLEAIDYINPDVIVDMSVPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAEKTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPINAAYGALSDLV
Q8ZUB0/4-137_284-298              --LFGFGGVGRTYAELLYQKT---------SLRLCAVFDSGGGVAKKECFSWGEVKELLKTARGSVSKSG-LGK--AVSPDEALDY--CQVIVDVSPPNYETGEPSLSLYKKAAAKGLAVVTANKAPLALAFREV------AYKRLFYKATVMAGT------------GAGRKETAYVLLNDT-
A0A087S1Z6/3-166_311-327          IILCGFGVVGQSLVKLFESRAEDLYAKYGLKPRVVGVFDSKGSAVNPSGLELNKLIEV-KKKFGTVKNYADTKN--TMSGIEMLKNVEADVLIETTASNYKDAEPGMTHIITAMKKGMHVISVNKGPLALAFPSLMELATYNQVMFKFSGTVGGGTPILDYAKNSLSRGAGGMETASSILRDLL
S2E4L0/3-166_311-327              IILCGFGVVGQSLVKLFNSRSEDLYAKYGLKPRVIGVFDSKGSAVDKAGLELDKLIEV-KKKFGTVKNYANTKN--NMSGVDMIKNLEADVLIETTASNYKDAEPGMTHIISAMKKRMHVISVNKGPLALAFPSLMELATYNQVIFKFSGTVGGGTPILDYAKNSLRKGAGGMETASSILRDLL
C3MW08/5-145_291-307              --LIGYGNVGKAFRRLLHEKRDSYPILQNVEIA---------------GMLTRQGLMV-----GDKENFS-PDK--QITVLEAIDFINPDVIVDMSAPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAERTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPTNAAYGALTDLV
A0A0E3KX87/7-152_311-317          -SILGFGAIGQGVAEVLLMKKEYLE-SIGLEVLVVAVVDSKGATVNPEGVDLADCLAR-KRTMGTVAIE-------KLTGVEVIKSVDHELVIETTPTNIVTGGAGLQNMLTAFEIGKDVITSNKGPLTLKYTELMEAAKASGSNFRFEATVGGSM------------GAGPIET---------
A0A0E3NKK9/7-152_311-317          -SILGFGAIGQGVAEVLLMKKEYLE-SIGLEVLVVAVVDSKGATVNPEGVDLADCLAR-KRTMGTVAIE-------KLTGVEVIKSVDHELVIETTPTNIVTGGAGLQNMLTAFEIGKDVITSNKGPLTLKYTELMEAAKASGSNFRFEATVGGSM------------GAGPIET---------
A0A0E3S273/8-152_311-326          --ILGFGAIGQGVAEVLLMKKEYLE-SIGLEVLVVAVVDSKGATVNPEGVDLADCLAR-KRTVGTVAIE-------KLTGVEIIRSIAHELVIETTPTNIVTGGVGLQNMFTAFETGKDVVTSNKGPLTLKYRELMEAAKAAGSNFRFEATVGGSM------------GAGPIETASAVLSDLV
A0A429G5G5/4-165_309-325          -ILMGLGVVGRSFLRMLIEKSPELRLKYGLNPTLVAVADSTSAVQDERGLDPKEILDM-KVKKGSLSGHA-CEV--GMRGVELIRGVEAEVLIDVTPSNFKTGEPSLSYIKAALNTGKHVITASKGPFALEMPALIEMFQESGLRLLFSGTVGGGVPFVRFVRKCLIKGAGGDETAMALIRDLV
Q9UX47/5-145_291-307              --LIGYGNVGKAFRRLLHEKKDNYPILQGVEIA---------------GIITRQGLMV-----GDKENFS-PDK--QLTVLEAIDYINPDVIVDMSVPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAEKTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPINAAYGALSDLV
D0KT64/5-145_291-307              --LIGYGNVGKAFRRLLHEKKDNYPILQGVEIA---------------GIITRQGLMV-----GDKENFS-PDK--QLTVLEAIDYINPDVIVDMSVPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAEKTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPINAAYGALSDLV
C4KHL4/5-145_291-307              --LIGYGNVGKAFRRLLHEKRDSYPILQNVEIA---------------GMLTRQGLMV-----GDKENFS-PDK--QITVLEAIDFINPDVIVDMSAPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAERTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPTNAAYGALTDLV
C3N651/5-145_291-307              --LIGYGNVGKAFRRLLHEKRDSYPILQNVEIA---------------GMLTRQGLMV-----GDKENFS-PDK--QITVLEAIDFINPDVIVDMSAPNYKDGEPSVSAYIKALSRKIHVITVNKAPLALKFREIFEVAERTGAKIGFQGTVMSGTPSINLFRIQ-PPGAGPTNAAYGALTDLV
#=GC scorecons                    0164969479544456734744242133545433323143232212218544343634041219444432022200455447474354466577564474456665443444854454587747959778465564636434533537468945654222223111129995466633353653
#=GC scorecons_70                 __*_***_**______*__*____________________________*______*_______*_________________*_*_____**_**_*__*___*_________*______***_**_****_*__*_*__________*__**__*_____________***__***_____*__
#=GC scorecons_80                 ____*_*_**______*__*____________________________*______________*_________________*________________*_____________*______***_**_****_________________*__**________________***_____________
#=GC scorecons_90                 ____*_*__*_____________________________________________________*________________________________________________*______*____*_*__*____________________**________________***_____________
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