# STOCKHOLM 1.0
#=GF ID 3.40.50.670/FF/000011
#=GF DE DNA topoisomerase 2
#=GF AC 3.40.50.670/FF/000011
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 29.417
#=GS P12531/420-551_596-679      AC P12531
#=GS P12531/420-551_596-679      OS Trypanosoma brucei brucei
#=GS P12531/420-551_596-679      DE DNA topoisomerase 2
#=GS P12531/420-551_596-679      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS P12531/420-551_596-679      DR GO; GO:0003918; GO:0005634; GO:0005739; GO:0006265; GO:0020023; 
#=GS P12531/420-551_596-679      DR EC; 5.6.2.3; 
#=GS Q4QF53/428-553_600-683      AC Q4QF53
#=GS Q4QF53/428-553_600-683      OS Leishmania major
#=GS Q4QF53/428-553_600-683      DE DNA topoisomerase 2
#=GS Q4QF53/428-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4QF53/428-553_600-683      DR GO; GO:0020023; 
#=GS O61078/422-553_600-683      AC O61078
#=GS O61078/422-553_600-683      OS Leishmania chagasi
#=GS O61078/422-553_600-683      DE DNA topoisomerase 2
#=GS O61078/422-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania chagasi; 
#=GS O61078/422-553_600-683      DR EC; 5.6.2.3; 
#=GS F9W9A3/420-551_596-679      AC F9W9A3
#=GS F9W9A3/420-551_596-679      OS Trypanosoma congolense IL3000
#=GS F9W9A3/420-551_596-679      DE DNA topoisomerase 2
#=GS F9W9A3/420-551_596-679      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Nannomonas; Trypanosoma congolense; 
#=GS A0A1X0NUH3/428-551_596-679  AC A0A1X0NUH3
#=GS A0A1X0NUH3/428-551_596-679  OS Trypanosoma theileri
#=GS A0A1X0NUH3/428-551_596-679  DE DNA topoisomerase 2
#=GS A0A1X0NUH3/428-551_596-679  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanosoma theileri; 
#=GS A0A1G4I7P1/420-551_596-679  AC A0A1G4I7P1
#=GS A0A1G4I7P1/420-551_596-679  OS Trypanosoma equiperdum
#=GS A0A1G4I7P1/420-551_596-679  DE DNA topoisomerase 2
#=GS A0A1G4I7P1/420-551_596-679  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS A0A3P3Z213/428-553_600-683  AC A0A3P3Z213
#=GS A0A3P3Z213/428-553_600-683  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3Z213/428-553_600-683  DE DNA topoisomerase 2
#=GS A0A3P3Z213/428-553_600-683  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS A0A1E1IS39/428-553_600-683  AC A0A1E1IS39
#=GS A0A1E1IS39/428-553_600-683  OS Leishmania guyanensis
#=GS A0A1E1IS39/428-553_600-683  DE DNA topoisomerase 2
#=GS A0A1E1IS39/428-553_600-683  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS E9AQC1/422-553_600-683      AC E9AQC1
#=GS E9AQC1/422-553_600-683      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AQC1/422-553_600-683      DE DNA topoisomerase 2
#=GS E9AQC1/422-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4HWL4/428-553_600-683      AC A4HWL4
#=GS A4HWL4/428-553_600-683      OS Leishmania infantum
#=GS A4HWL4/428-553_600-683      DE DNA topoisomerase 2
#=GS A4HWL4/428-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A088RLN4/428-553_600-683  AC A0A088RLN4
#=GS A0A088RLN4/428-553_600-683  OS Leishmania panamensis
#=GS A0A088RLN4/428-553_600-683  DE DNA topoisomerase 2
#=GS A0A088RLN4/428-553_600-683  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9BCH0/428-553_600-683      AC E9BCH0
#=GS E9BCH0/428-553_600-683      OS Leishmania donovani BPK282A1
#=GS E9BCH0/428-553_600-683      DE DNA topoisomerase 2
#=GS E9BCH0/428-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS Q38EZ6/420-551_596-679      AC Q38EZ6
#=GS Q38EZ6/420-551_596-679      OS Trypanosoma brucei brucei TREU927
#=GS Q38EZ6/420-551_596-679      DE DNA topoisomerase 2
#=GS Q38EZ6/420-551_596-679      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS A4H891/428-553_600-683      AC A4H891
#=GS A4H891/428-553_600-683      OS Leishmania braziliensis
#=GS A4H891/428-553_600-683      DE DNA topoisomerase 2
#=GS A4H891/428-553_600-683      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GF SQ 14
P12531/420-551_596-679              DATSTRRDPKHTRTLIVTEGDSAKALAQNSLSSDQKRYTGVFPLRGKLLNVRNKNLKRLRNCKELQELFCALGLELDKDYTDADELRYQRILIMTDQDADGSHIKGLVINAFESLWPSLLVRNPGFISIFSTTTAEGKEYFKDMEKHTMRLLVDRSDHKLLDNVFDSQEVEWRKDWMTKANAFTGEVDIDRSKKMLTVTDFVHKEMVHFALVGNAR
Q4QF53/428-553_600-683              ------PDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLSLGLELGKEYRSPAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTTTAEGKEYFADMEKNVMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEVDIDRSKKTLTIPEFVHKEMVHFALVGNAR
O61078/422-553_600-683              DATSSQPDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKGLQDLFLSLGLELGKEYRSPAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTTTAEGKEYFADMEKNIMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEVDIDRSKKTLTIPEFVHKEMVHFALVGNAR
F9W9A3/420-551_596-679              DATSTRRDPKNIRTLIVTEGDSAKALAQNSLSSDQKRYTGVFPLRGKLLNVRNKNLKRLRNCKELQELFCALGLELDKDYKDADELRYQRILVMTDQDADGSHIKGLVINAFESLWPSLLVRNPGFISIFSTTTVEGKEYFKDMEKHTMRLLVDRNDHKLLDNVFDSQEVEWRKDWMTKANAFTGEVDIDRSKKTLTVPDFVHKEMVHFALVGNAR
A0A1X0NUH3/428-551_596-679          --------PRCTRTLIVTEGDSAKALAQNSLSSEQKRYTGVFPLRGKLLNVRNKNLKRLKNCKELQELFCALGIELGKVYKDADELRYQRLLIMTDQDADGSHIKGLVINAFEALWPTLLMRTPGFISVFSTTTAEGKEYFKDMEKHTMRLVVDRSDHKLLDNVFDSQEVEWRKDWMTKANAFTGEVDIDRSKKNLTLPEFVHKEMVHFALAGNAR
A0A1G4I7P1/420-551_596-679          DATSTRRDPKHTRTLIVTEGDSAKALAQNSLSSDQKRYTGVFPLRGKLLNVRNKNLKRLRNCKELQELFCALGLELDKDYTDADELRYQRILIMTDQDADGSHIKGLVINAFESLWPSLLVRNPGFISIFSTTTAEGKEYFKDMEKHTMRLLVDRSDHKLLDNVFDSQEVEWRKDWMTKANAFTGEVDIDRSKKMLTVTDFVHKEMVHFALVGNAR
A0A3P3Z213/428-553_600-683          ------PDGRNIRTLIITEGDSAKALALNSLSSDQKKYCGVFPLRGKLLNVRNKNLKRLKMCKELQDLFLALGLELGKEYRTPDELRYQRLLVMTDQDADGSHIKGLVINAFESLWPTLLQNNPGYISLFSTTTAEGKEYFADMEKNIMRLTVDAKDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKSLTIPEFVHKEMVHFALVGNAR
A0A1E1IS39/428-553_600-683          ------PDGRNIRTLIITEGDSAKALALNSLSSDQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLALGLELGKEYRTPDELRYQRLLVMTDQDADGSHIKGLVINAFESLWPTLLQNNPGYISLFSTTTAEGKEYFADMDKNIMRLTVDAKDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKSLTIPEFVHKEMVHFALVGNAR
E9AQC1/422-553_600-683              DATSSRSDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLSLGLELGKEYRTLAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTTTAEGKEYFADMEKNIMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKMLTIPEFVHKEMVHFALVGNAR
A4HWL4/428-553_600-683              ------PDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLSLGLELGKEYRSPAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTTTAEGKEYFADMEKNIMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKTLTIPEFVHKEMVHFALVGNAR
A0A088RLN4/428-553_600-683          ------PDGRNIRTLIITEGDSAKALALNSLSSDQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLALGLELGKEYRTPDELRYQRLLVMTDQDADGSHIKGLVINAFESLWPTLLQNNPGYISLFSTTTAEGKEYFADMDKNIMRLTVDAKDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKSLTIPEFVHKEMVHFALVGNAR
E9BCH0/428-553_600-683              ------PDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLSLGLELGKEYRSPAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTTTAEGKEYFADMEKNIMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKTLTIPEFVHKEMVHFALVGNAR
Q38EZ6/420-551_596-679              DATSTRRDPKHTRTLIVTEGDSAKALAQNSLSSDQKRYTGVFPLRGKLLNVRNKNLKRLRNCKELQELFCALGLELDKDYTDADELRYQRILIMTDQDADGSHIKGLVINAFESLWPSLLVRNPGFISIFSTTTAEGKEYFKDMEKHTMRLLVDRSDHKLLDNVFDSQEVEWRKDWMTKANAFTGEVDIDRSKKMLTVTDFVHKEMVHFALVGNAR
A4H891/428-553_600-683              ------PDGRNIRTLIITEGDSAKALALNSLSSDQKKYCGVFPLRGKLLNVRNKNLKRLKMCKELQDLFLALGLELGKEYRTPDELRYQRLLVMTDQDADGSHIKGLVINAFESLWPTLLQNNPGYISLFSTTTAEGKEYFADMEKNIMRLTVDAKDHQLLDSVFDAAEVEWRKEWMTKANAFQGEIDIDRSKKSLTIPEFVHKEMVHFALVGNAR
#=GC scorecons                      111111475756999979999999999599999799795999999999999999999997599899799469989969695455999999697999999999999999999997999499457997996999998999999599896596959954996999699965999999799999999599799999994996679999999999979999
#=GC scorecons_70                   _______*_*__***************_**********_*********************_********_********_*____*********************************_**__******_************_****__***_**__******_***__***************_**********_*********************
#=GC scorecons_80                   _______*_*__****_**********_*****_**_*_*********************_*****_**__*****_*_*____******_*_************************_**__******_************_****__*_*_**__**_***_***__******_********_**_*******_**__*****************
#=GC scorecons_90                   ____________****_**********_*****_**_*_********************__*****_**__**_**_*_*____******_*_********************_***_**___**_**_*****_******_****__*_*_**__**_***_***__******_********_**_*******_**___***********_****
//