# STOCKHOLM 1.0 #=GF ID 3.40.50.150/FF/000333 #=GF DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GF AC 3.40.50.150/FF/000333 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 81.715 #=GS Q55AX2/1240-1455 AC Q55AX2 #=GS Q55AX2/1240-1455 OS Dictyostelium discoideum #=GS Q55AX2/1240-1455 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q55AX2/1240-1455 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q55AX2/1240-1455 DR GO; GO:0005634; GO:0006974; GO:0031151; GO:0031156; GO:0034729; #=GS Q55AX2/1240-1455 DR EC; 2.1.1.43; #=GS Q4GZF2/94-275 AC Q4GZF2 #=GS Q4GZF2/94-275 OS Trypanosoma brucei brucei TREU927 #=GS Q4GZF2/94-275 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q4GZF2/94-275 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q4GZF2/94-275 DR GO; GO:0005634; GO:0018024; GO:0020033; GO:0031981; GO:0051726; #=GS Q4QD41/98-279 AC Q4QD41 #=GS Q4QD41/98-279 OS Leishmania major #=GS Q4QD41/98-279 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q4QD41/98-279 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4QD41/98-279 DR GO; GO:0018024; GO:0020033; GO:0031981; GO:0051726; #=GS Q581Z0/111-295 AC Q581Z0 #=GS Q581Z0/111-295 OS Trypanosoma brucei brucei TREU927 #=GS Q581Z0/111-295 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q581Z0/111-295 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q581Z0/111-295 DR GO; GO:0005634; GO:0005694; #=GS F0ZEK7/893-1104 AC F0ZEK7 #=GS F0ZEK7/893-1104 OS Dictyostelium purpureum #=GS F0ZEK7/893-1104 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS F0ZEK7/893-1104 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS A0A1G4I924/111-295 AC A0A1G4I924 #=GS A0A1G4I924/111-295 OS Trypanosoma equiperdum #=GS A0A1G4I924/111-295 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS A0A1G4I924/111-295 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS A0A3S5H5V6/115-299 AC A0A3S5H5V6 #=GS A0A3S5H5V6/115-299 OS Leishmania donovani #=GS A0A3S5H5V6/115-299 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS A0A3S5H5V6/115-299 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9AL12/115-299 AC E9AL12 #=GS E9AL12/115-299 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AL12/115-299 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS E9AL12/115-299 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS C9ZHT8/94-275 AC C9ZHT8 #=GS C9ZHT8/94-275 OS Trypanosoma brucei gambiense DAL972 #=GS C9ZHT8/94-275 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS C9ZHT8/94-275 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; #=GS A4HT24/115-299 AC A4HT24 #=GS A4HT24/115-299 OS Leishmania infantum #=GS A4HT24/115-299 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS A4HT24/115-299 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS Q4QIU2/115-299 AC Q4QIU2 #=GS Q4QIU2/115-299 OS Leishmania major #=GS Q4QIU2/115-299 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q4QIU2/115-299 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9B8Z9/115-299 AC E9B8Z9 #=GS E9B8Z9/115-299 OS Leishmania donovani BPK282A1 #=GS E9B8Z9/115-299 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS E9B8Z9/115-299 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9BEX9/97-279 AC E9BEX9 #=GS E9BEX9/97-279 OS Leishmania donovani BPK282A1 #=GS E9BEX9/97-279 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS E9BEX9/97-279 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A4HYJ5/97-279 AC A4HYJ5 #=GS A4HYJ5/97-279 OS Leishmania infantum #=GS A4HYJ5/97-279 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS A4HYJ5/97-279 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9AUE2/98-279 AC E9AUE2 #=GS E9AUE2/98-279 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AUE2/98-279 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS E9AUE2/98-279 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS Q9BJ44/182-363 AC Q9BJ44 #=GS Q9BJ44/182-363 OS Leishmania major #=GS Q9BJ44/182-363 DE Histone-lysine N-methyltransferase, H3 lysine-79 specific #=GS Q9BJ44/182-363 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GF SQ 16 Q55AX2/1240-1455 LKHYISFSQEVYGEAEPTLLRHWIHLGLIKPTDVFCDIGCGIGNVLFQLAAQVGCRVIGVEIRKDLYDISQSMLEIYKKRSLELGLHPSTQQIKIYNCDVKGSLEFD--FSE---PNVFFMHNTCFGPELEISIMELFKKYSKPGTKVITMKTLCPRFKPSDKKTKPWGIFKYPYESYEMEEGSLSWRSATNCSFYSFTIDDKDSDIVTDQTHLNRVILST Q4GZF2/94-275 -------------SVLPPFVARLLRVANVTADDTFYDLGCGNGSVLFHVALATGASCVGVEINEHNAKVAKEAWTHLRP-VFEKRRGRKL-DVSIVCGDFCKVLKQDNYFSS---SCVVWIANLLMPRFVNHYLSERLRSLPI-GSRVLCMEDLYPHSRSVAAARDPDAFEKFEMVDYRWQEDSVEWSPASG-PFYLYIKR-------------------S Q4QD41/98-279 -------------SILPPFVTRLIRIANVAPGETFYDLGCGNGSVLFQVAALTGARCVGVEINPHNAEVANAAWAFLRP-IFEAQFKREL-SVEIVCADFCTLLRDAVYFPT---PCVIWAANLLLPRPVNHYLSERLRSVPR-GTRIMCFEDMYPHSRSLARLRDPDAFEKFDMLDYEWQPDSVEWCSNTG-RFFLYVKR-------------------T Q581Z0/111-295 -------------SLLPTFVSRMVRLMEITSEDTFYDLGCGNGSILFQVAFLTGARCVGIEISEHNAKVAKKAWEVIRP-ELEGSSGRSMPEVNIITSDMTKILADERLFESERGKTVILLSNLLFPKSLTHYLSERFRRVPS-GTRILCFDDLYPHSRSVAAIRDPEAFRLFAMTDYRWQECSVEWCTRDG-PFFIHRRR-------------------- F0ZEK7/893-1104 LKQYTSFSQEVYGEANPKLIRQWIRLGLVKPSDVFCDIGCGIGNVLFQVASMVGCRVIGFEIRKDLFEISQKMLNTYRQCSKELGLHESTQNIEFYNCDIKGQLDFD--FSK---VNVFFMHNTCFPPDLELYIMELFKKHSSNDTKVLTMKTLCPRFKPSDKIRKPWGIFKYPYESYEMAEGSLSWKSAYKCSFYSFTIDDKDNFTNTDPSKLQI----N A0A1G4I924/111-295 -------------SLLPTFVSRMVRLMEITSEDTFYDLGCGNGSILFQVAFLTGARCVGIEISEHNAKVAKKAWEVIRP-ELEGSSGRSMPEVNIITSDMTKILADERLFESERGKTVILLSNLLFPKSLTHYLSERFRRVPS-GTRILCFDDLYPHSRSVAAIRDPEAFRLFAMTDYRWQECSVEWCTRDG-PFFIHRRR-------------------- A0A3S5H5V6/115-299 -------------SLLTPFVTRLVRLMNITEKDTFYDFGCGNGSVLFQVAFMTGAKCVGVEISEHNADVAREAWQLLRQ-VLEKKYDRPMPRVEIITADLAELLSTPTYFDEEEGQTAILISNLLFPKPLTHFLSERLRSAPV-GTRILCFDDLYPHARSVAPYRDPGAFELFEMKDYLWQEMSVEWCSMEG-RFFIHTRK-------------------- E9AL12/115-299 -------------SLLTPFVTRLVRLMNITKNDTFYDFGCGNGSVLFQVAFMTGAKCVGVEISEHNADVAREAWQLLRQ-VLEKKYDRPMPRMEIITADLAELLSTPTYFDEEEGQTAILISNLLFPKPLTHFLSERLRSTHV-GTRILCFDDLYPHARSVATYRDPGAFELFDMKDYLWQEMSVEWCSMEG-RFFIHTRK-------------------- C9ZHT8/94-275 -------------SVLPPFVARLLRVANVTADDTFYDLGCGNGSVLFHVALATGASCVGVEINEHNAKVAKEAWTHLRP-VFEKRRGRKL-DVSIVCGDFCKVLKQDNYFSS---SCVVWIANLLMPRFVNHYLSERLRSLPI-GSRVLCMEDLYPHSRSVAAARDPDAFEKFEMVDYRWQEDSVEWSPASG-PFYLYIKR-------------------S A4HT24/115-299 -------------SLLTPFVTRLVRLMNITEKDTFYDFGCGNGSVLFQVAFMTGAKCVGVEISEHNADVAREAWQLLRQ-VLEKKYDRPMPRVEIITADLAELLSTPTYFDEEEGQTAILISNLLFPKPLTHFLSERLRSAPV-GTRILCFDDLYPHARSVAPYRDPGAFELFEMRDYLWQEMSVEWCSMEG-RFFIHTRK-------------------- Q4QIU2/115-299 -------------SLLTPFVTRLVRLMNITEKDTFYDFGCGNGSVLFQVAFMTGAKCVGVEISEHNADVAREAWQLLRQ-VLEKKYDRPMPRVEIITADLAELLSTPTYFDEEEGQTAILISNLLFPKPLTHFLSERLRSAPV-GTRILCFDDLYPHARSVASYRDPGAFELFEMKDYFWQEMSVEWCSMEG-RFFIHTRK-------------------- E9B8Z9/115-299 -------------SLLTPFVTRLVRLMNITEKDTFYDFGCGNGSVLFQVAFMTGAKCVGVEISEHNADVAREAWQLLRQ-VLEKKYDRPMPRVEIITADLAELLSTPTYFDEEEGQTAILISNLLFPKPLTHFLSERLRSAPV-GTRILCFDDLYPHARSVAPYRDPGAFELFEMKDYLWQEMSVEWCSMEG-RFFIHTRK-------------------- E9BEX9/97-279 ------------KSILPPFVTRLIRIANVASGETFYDLGCGNGSVLFQVAALTGARCVGVEINPHNAELANAAWVFLRP-IFETQFRREL-SVEIVCADFCTLLRDAVYFPT---PCVIWAANLLLPRPVNHYLSERLRSVPR-GTRIMCFEDMYPHSRSLARLRDPDAFEKFDMVDYEWQPDSVEWCSNTG-RFFLYVKR-------------------T A4HYJ5/97-279 ------------KSILPPFVTRLIRIANVASGETFYDLGCGNGSVLFQVAALTGARCVGVEINPHNAELANAAWVFLRP-IFETQFRREL-SVEIVCADFCTLLRDAVYFPT---PCVIWAANLLLPRPVNHYLSERLRSVPR-GTRIMCFEDMYPHSRSLARLRDPDAFEKFDMVDYEWQPDSVEWCSNTG-RFFLYVKR-------------------T E9AUE2/98-279 -------------SVLPPFVTRLIRIANMASGETFYDLGCGNGSVLFQVAALTGARCVGVEINPHNAELASTAWVFLQP-IFEAQFKRKL-SVEIVCADFCTLLRDAAYFPA---PCVIWAANLLLPRPVNHYLSERLRSVPR-GTRIMCFEDMYPHSRSLARLRDPDAFEKFDMLDYEWQPDSVEWCSNTG-PFFLYVKR-------------------T Q9BJ44/182-363 -------------SILPPFVTRLIRIANVAPGETFYDLGCGNGSVLFQVAALTGARCVGVEINPHNAEVANAAWAFLRP-IFEAQFKREL-SVEIVCADFCTLLRDAVYFPT---PCVIWAANLLLPRPVNHYLSERLRSVPR-GTRIMCFEDMYPHSRSLARLRDPDAFEKFDMLDYEWQPDSVEWCSNTG-RFFLYVKR-------------------T #=GC scorecons 00000000000006456577465676456543769795999696899879446966679699446555664466335750459343364523757444943449334249441013466444965675464567695675363077776665677974764633769366457453693566397695633604974644500000000000000000002 #=GC scorecons_70 _____________*__*_**_*_***__*___*****_***_********__***__*****__*___**__*____*____*____*____*_*___*____*_____*_______*____**__*__*__****_**__*__******__*****_**_*__***_**__*___**__*__****_*__*__**_________________________ #=GC scorecons_80 ___________________*____*_______*_*_*_***_*_******___*___**_**_______________*____*___________*___*____*_____*____________*___*________*__*_____****_____*_*__*_____*_*_____*____*_____*__*_______**_________________________ #=GC scorecons_90 __________________________________*_*_***_*_***__*___*____*_**____________________*_______________*____*_____*____________*____________*___________________*__________*__________*_____*__*_______*__________________________ //