# STOCKHOLM 1.0 #=GF ID 3.40.50.150/FF/000287 #=GF DE Protein-lysine N-methyltransferase EFM4 #=GF AC 3.40.50.150/FF/000287 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 85.308 #=GS P40516/38-243 AC P40516 #=GS P40516/38-243 OS Saccharomyces cerevisiae S288C #=GS P40516/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS P40516/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS P40516/38-243 DR GO; GO:0005737; GO:0016192; GO:0016279; GO:0018026; GO:0018027; #=GS Q9P7Z3/7-214 AC Q9P7Z3 #=GS Q9P7Z3/7-214 OS Schizosaccharomyces pombe 972h- #=GS Q9P7Z3/7-214 DE Protein-lysine N-methyltransferase efm4 #=GS Q9P7Z3/7-214 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; #=GS Q9P7Z3/7-214 DR GO; GO:0005829; GO:0016279; GO:2000765; #=GS A0A0D1CBX8/449-672 AC A0A0D1CBX8 #=GS A0A0D1CBX8/449-672 OS Ustilago maydis 521 #=GS A0A0D1CBX8/449-672 DE Protein-lysine N-methyltransferase EFM4 #=GS A0A0D1CBX8/449-672 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago; Ustilago maydis; #=GS Q0U0M2/389-594 AC Q0U0M2 #=GS Q0U0M2/389-594 OS Parastagonospora nodorum SN15 #=GS Q0U0M2/389-594 DE Protein-lysine N-methyltransferase EFM4 #=GS Q0U0M2/389-594 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae; Parastagonospora; Parastagonospora nodorum; #=GS B9WBK7/10-229 AC B9WBK7 #=GS B9WBK7/10-229 OS Candida dubliniensis CD36 #=GS B9WBK7/10-229 DE Protein-lysine N-methyltransferase EFM4 #=GS B9WBK7/10-229 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida dubliniensis; #=GS Q6C6B1/10-218 AC Q6C6B1 #=GS Q6C6B1/10-218 OS Yarrowia lipolytica CLIB122 #=GS Q6C6B1/10-218 DE Protein-lysine N-methyltransferase EFM4 #=GS Q6C6B1/10-218 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS Q75AI6/9-197 AC Q75AI6 #=GS Q75AI6/9-197 OS Eremothecium gossypii ATCC 10895 #=GS Q75AI6/9-197 DE Protein-lysine N-methyltransferase EFM4 #=GS Q75AI6/9-197 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium; Eremothecium gossypii; #=GS R9XBW2/9-202 AC R9XBW2 #=GS R9XBW2/9-202 OS Saccharomycetaceae sp. 'Ashbya aceri' #=GS R9XBW2/9-202 DE Protein-lysine N-methyltransferase EFM4 #=GS R9XBW2/9-202 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomycetaceae sp. 'Ashbya aceri'; #=GS C4YIM4/8-223 AC C4YIM4 #=GS C4YIM4/8-223 OS Candida albicans WO-1 #=GS C4YIM4/8-223 DE Protein-lysine N-methyltransferase EFM4 #=GS C4YIM4/8-223 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida albicans; #=GS A0A0L8VNV3/30-235 AC A0A0L8VNV3 #=GS A0A0L8VNV3/30-235 OS Saccharomyces sp. 'boulardii' #=GS A0A0L8VNV3/30-235 DE Protein-lysine N-methyltransferase EFM4 #=GS A0A0L8VNV3/30-235 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; #=GS H0GHX3/38-243 AC H0GHX3 #=GS H0GHX3/38-243 OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 #=GS H0GHX3/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS H0GHX3/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; #=GS A0A1D8PHH0/10-229 AC A0A1D8PHH0 #=GS A0A1D8PHH0/10-229 OS Candida albicans SC5314 #=GS A0A1D8PHH0/10-229 DE Protein-lysine N-methyltransferase EFM4 #=GS A0A1D8PHH0/10-229 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida albicans; #=GS A0A1H6PTD4/10-218 AC A0A1H6PTD4 #=GS A0A1H6PTD4/10-218 OS Yarrowia lipolytica #=GS A0A1H6PTD4/10-218 DE Protein-lysine N-methyltransferase EFM4 #=GS A0A1H6PTD4/10-218 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS N1P222/30-235 AC N1P222 #=GS N1P222/30-235 OS Saccharomyces cerevisiae CEN.PK113-7D #=GS N1P222/30-235 DE Protein-lysine N-methyltransferase EFM4 #=GS N1P222/30-235 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS B3LTR7/38-243 AC B3LTR7 #=GS B3LTR7/38-243 OS Saccharomyces cerevisiae RM11-1a #=GS B3LTR7/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS B3LTR7/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS B5VKN7/38-243 AC B5VKN7 #=GS B5VKN7/38-243 OS Saccharomyces cerevisiae AWRI1631 #=GS B5VKN7/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS B5VKN7/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C8ZAI4/38-243 AC C8ZAI4 #=GS C8ZAI4/38-243 OS Saccharomyces cerevisiae EC1118 #=GS C8ZAI4/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS C8ZAI4/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS G2WG84/38-243 AC G2WG84 #=GS G2WG84/38-243 OS Saccharomyces cerevisiae Kyokai no. 7 #=GS G2WG84/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS G2WG84/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS A6ZVK9/38-243 AC A6ZVK9 #=GS A6ZVK9/38-243 OS Saccharomyces cerevisiae YJM789 #=GS A6ZVK9/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS A6ZVK9/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C7GVY8/38-243 AC C7GVY8 #=GS C7GVY8/38-243 OS Saccharomyces cerevisiae JAY291 #=GS C7GVY8/38-243 DE Protein-lysine N-methyltransferase EFM4 #=GS C7GVY8/38-243 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GF SQ 20 P40516/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWKP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV Q9P7Z3/7-214 SKLGTKQYWDNVYEREVSNFTEF-NDEGEVWFGE-EAEERIVQWLEDHISTSF--REVSEAAPFRVLDLGTGNGHLLFRLLEE---EDTL--LPSPCQLVGVDYSEAAIVLAKNIARHRQFS-DKVKFQQLDIIKD--SKFCS-------------KDWDLILDKGTFDAISLSG---ELLDGRPL-NSVYVDRVRGMLSPNGIFLITSCNWTIQELEERFTKNG-FIVHSTVPVPVF----- A0A0D1CBX8/449-672 SKLGTKQHWDDVYAREVTNFNEI-GEEGEVWFGE-DAVMRMIRYLERYYTETVAGTFSCDASAPTVLDLGTGNGHLLFEMIES---SADLEEIISADRLVGIDYSAASIELAKSIGVKRGGDCERVTFTTADLLDS--SSVESLLHLPTSQLGAADQGWDLVCDKGTLDAIALSS---QPINGSLP-IDLYSNAVNTLVKKHGIFLITSCNFTEQELTARFTSRG-FQVQHVLPTP------- Q0U0M2/389-594 --LGQKSYWDKAYTTERDNFASNAADEGTIWFSDAGAEERMLSFLEDLSDEGALNKEKT-----RFLDLGTGNGHLLFALRED---EWEG-------EMVGVDYSGESVRLATEIRGSKGDQYEDIKLEEWDILNQQPGEWLG-------------DGFDVVLDKGTFDAICLSQD--TDAQGRRI-CEGYGERVAPLVKPGGRFLITSCNWTEEELKSWFEGGR-FRFSGKVKYPSFTF--- B9WBK7/10-229 SKLGSQEYWNNFYKKEQENFNENDEDTGECWFDDSDAESKMIQFIIDKLNDEELPEEISSQSVIRFLDLGTGNGHLLFQLSEDINEENEG---DKTFEYIGIDYSPDSVEFAKGVAKRKHSE-LKVNFDQVDLLQV-NCSFLQ-------------NKFDILLDKGTLDAIALNQDPLADFNGKIG-MDVYASQVEKMMVKGSILLITSCNFTKDELIKIITKDTKLEVWDEINYPSFQ---- Q6C6B1/10-218 SKLGTKQYWDEFYNLEKNNYAENPNDSGECWFSDSGAEEKMVDFLVDEEEQGQGESLISLD--CKMCDLGTGNGRLLFSIREG---GFTG-------HLTGLDYSQPAVEFSTKIAEQEEME--NITFEHADFLGD-AAMWST-----------GNRQWDVVLDKGTLDAIALSD---IKYEGKTG-VQTYPHVVQHMVKTRGVVLITSCNFTSDELVKIMTTDTCLKEWKHVKYPSFR---- Q75AI6/9-197 SKLGTREYWDEFYAVEQRNFEADAQDTGECWFDEDRAAERMVEFLEEHVGEWRIAPDAA------VLDVGCGNGHLLFALADA---GFHG-------RLEGVDYSERSVQLARAIGATHDAD---VGFHAADVFS---AAWQP-------------GVFDVVLDKGTLDAIALSG---MQPAGAASVPAAYAAVVERVLAPGGVLLITSCNFTEDELVRLVEAGSGL---------------- R9XBW2/9-202 SKLGTREYWDEFYAVEQRNFEADAQDTGECWFDEDRAAERMVEFLEEHVGEWRIAPEAA------VLDVGCGNGHLLFALADA---GFRG-------RLEGVDYSERSVQLARAIGATHDAE---VSFHAADVFS---AEWQP-------------GVFDVVLDKGTLDAIALSG---MQPVGAASVPAAYAAVMERILAPGGVFLITSCNFTEDELVHLVEAGSSLRKCGR----------- C4YIM4/8-223 NCYS----WNNFYKKEQDNFNENEEDTGECWFDDSDAESKMIQFIIDKLNEEELPEEISSQSVVRFLDLGTGNGHLLFQLSEDINEEYEG---DKTFEYTGIDYSPDSVKFASGVAKRKYSE-LKVNFEQVDLLQE-SCSFLQ-------------NKFDILLDKGTLDAIALNQESLADFNGKIG-MDVYASQVEKMMVQGSILLITSCNFTKDELIKIITKDTNLEVWDEINYPSFQ---- A0A0L8VNV3/30-235 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV H0GHX3/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV A0A1D8PHH0/10-229 SKLGSKEYWNNFYKKEQDNFNENEEDTGECWFDDSDAESKMIQFIIDKLNEEELPEEISSQSVVRFLDLGTGNGHLLFQLSEDINEEYEG---DKTFEYTGIDYSPDSVKFASGVAKRKYSE-LKVNFEQVDLLQE-SCSFLQ-------------NKFDILLDKGTLDAIALNQESLADFNGKIG-MDVYASQVEKMMVQGSILLITSCNFTKDELIKIITKDTNLEVWDEINYPSFQ---- A0A1H6PTD4/10-218 SKLGTKQYWDEFYNLEKNNYAENPNDSGECWFSDSGAEEKMVDFLVDEEEQGQGESLISLD--CKMCDLGTGNGRLLFSIREG---GFTG-------HLTGLDYSQPAVEFSTKIAEQEEME--NITFEHADFLGD-AAMWST-----------GNRQWDVVLDKGTLDAIALSD---IKYEGKTG-VQTYPHVVQHMVKTRGVVLITSCNFTSDELVKIMTTDTCLKEWKHVKYPSFR---- N1P222/30-235 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV B3LTR7/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV B5VKN7/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV C8ZAI4/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV G2WG84/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWKP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV A6ZVK9/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILKKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV C7GVY8/38-243 SKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENAS------VVDLGTGNGHMLFELHQT---EFQG-------KLVGIDYSEESVKLASNIAEATGVD-NFISFQQADIFS---GDWNP-------------GKYDIVLDKGTLDAISLSG---MKINGKLDVVDVYAGVVEKILEKDGIFLITSCNFTQDELVKIIETDN-LKMWKTIKYPVFQFGGV #=GC scorecons 768856479755943934984453485966995745964786477474444244344460000015597979997699473640006446000000046596999447846744764344360227485559564100435340000000000000445967799997999597400044459543145595448545634476699999979469955555454074344354463531111 #=GC scorecons_70 ****_*_***__*__*__**_____*_**_**_*__**_***_**_*___________*________***********_*_________*________*_*****__**_**__**_________*_*___*___________________________************_**________*_______*___*_______**_********_***_________*________*_______ #=GC scorecons_80 __**___***__*__*__**_____*_*__**_*__*__**__**_*____________________********_**_*____________________*_***__**__*__*____________*___*___________________________*__*********_**________*_______*___*_______*__********__**_________*________________ #=GC scorecons_90 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