# STOCKHOLM 1.0 #=GF ID 3.40.50.150/FF/000251 #=GF DE Putative RNA methylase #=GF AC 3.40.50.150/FF/000251 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 98.170 #=GS Q58120/177-350 AC Q58120 #=GS Q58120/177-350 OS Methanocaldococcus jannaschii DSM 2661 #=GS Q58120/177-350 DE tRNA (guanine(10)-N2)-dimethyltransferase #=GS Q58120/177-350 DR ORG; Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; Methanocaldococcus jannaschii; #=GS Q58120/177-350 DR EC; 2.1.1.213; #=GS O58076/154-329 AC O58076 #=GS O58076/154-329 OS Pyrococcus horikoshii OT3 #=GS O58076/154-329 DE Uncharacterized protein #=GS O58076/154-329 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus horikoshii; #=GS O58076/154-329 DR GO; GO:0000049; GO:0004809; GO:0030488; #=GS Q8TU64/172-352 AC Q8TU64 #=GS Q8TU64/172-352 OS Methanosarcina acetivorans C2A #=GS Q8TU64/172-352 DE N2-methylguanosine tRNA methyltransferase #=GS Q8TU64/172-352 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina acetivorans; #=GS Q8ZWT1/70-224 AC Q8ZWT1 #=GS Q8ZWT1/70-224 OS Pyrobaculum aerophilum str. IM2 #=GS Q8ZWT1/70-224 DE Uncharacterized protein #=GS Q8ZWT1/70-224 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; Pyrobaculum aerophilum; #=GS A9A3X1/150-315 AC A9A3X1 #=GS A9A3X1/150-315 OS Nitrosopumilus maritimus SCM1 #=GS A9A3X1/150-315 DE Putative RNA methylase #=GS A9A3X1/150-315 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Nitrosopumilus maritimus; #=GS T1FSK6/254-408 AC T1FSK6 #=GS T1FSK6/254-408 OS Helobdella robusta #=GS T1FSK6/254-408 DE Uncharacterized protein #=GS T1FSK6/254-408 DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; #=GS B1L6X4/131-305 AC B1L6X4 #=GS B1L6X4/131-305 OS Candidatus Korarchaeum cryptofilum OPF8 #=GS B1L6X4/131-305 DE Putative RNA methylase #=GS B1L6X4/131-305 DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; #=GS Q97Z87/141-314 AC Q97Z87 #=GS Q97Z87/141-314 OS Saccharolobus solfataricus P2 #=GS Q97Z87/141-314 DE Uncharacterized protein #=GS Q97Z87/141-314 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS Q5JID5/153-331 AC Q5JID5 #=GS Q5JID5/153-331 OS Thermococcus kodakarensis KOD1 #=GS Q5JID5/153-331 DE N2, N2-dimethylguanosine tRNA methyltransferase #=GS Q5JID5/153-331 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus kodakarensis; #=GS A9V3Y6/276-431 AC A9V3Y6 #=GS A9V3Y6/276-431 OS Monosiga brevicollis #=GS A9V3Y6/276-431 DE Predicted protein #=GS A9V3Y6/276-431 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A0A087RLK1/150-315 AC A0A087RLK1 #=GS A0A087RLK1/150-315 OS Marine Group I thaumarchaeote SCGC AAA799-D11 #=GS A0A087RLK1/150-315 DE tRNA-dimethyltransferase protein #=GS A0A087RLK1/150-315 DR ORG; Archaea; Thaumarchaeota; Marine Group I thaumarchaeote SCGC AAA799-D11; #=GS Q9HN57/1-161 AC Q9HN57 #=GS Q9HN57/1-161 OS Halobacterium salinarum NRC-1 #=GS Q9HN57/1-161 DE Uncharacterized protein #=GS Q9HN57/1-161 DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; #=GS C3MYF9/139-312 AC C3MYF9 #=GS C3MYF9/139-312 OS Sulfolobus islandicus M.14.25 #=GS C3MYF9/139-312 DE Putative RNA methylase #=GS C3MYF9/139-312 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS Q9UY84/153-329 AC Q9UY84 #=GS Q9UY84/153-329 OS Pyrococcus abyssi GE5 #=GS Q9UY84/153-329 DE tRNA (guanine(10)-N2)-dimethyltransferase #=GS Q9UY84/153-329 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus abyssi; #=GS Q9UY84/153-329 DR GO; GO:0000049; GO:0004809; GO:0030488; #=GS Q9UY84/153-329 DR EC; 2.1.1.213; #=GS Q8U3Q6/154-329 AC Q8U3Q6 #=GS Q8U3Q6/154-329 OS Pyrococcus furiosus DSM 3638 #=GS Q8U3Q6/154-329 DE Uncharacterized protein #=GS Q8U3Q6/154-329 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus furiosus; #=GS Q8U3Q6/154-329 DR GO; GO:0000049; GO:0004809; GO:0030488; #=GS A0A0E3L3V2/172-347 AC A0A0E3L3V2 #=GS A0A0E3L3V2/172-347 OS Methanosarcina sp. WH1 #=GS A0A0E3L3V2/172-347 DE tRNA-(G10-N2) methyltransferase #=GS A0A0E3L3V2/172-347 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WH1; #=GS A0A0E3NFT6/172-347 AC A0A0E3NFT6 #=GS A0A0E3NFT6/172-347 OS Methanosarcina sp. WWM596 #=GS A0A0E3NFT6/172-347 DE tRNA-(G10-N2) methyltransferase #=GS A0A0E3NFT6/172-347 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WWM596; #=GS A0A2Z2MDW5/153-333 AC A0A2Z2MDW5 #=GS A0A2Z2MDW5/153-333 OS Thermococcus profundus #=GS A0A2Z2MDW5/153-333 DE tRNA (Guanine-N2)-dimethyltransferase #=GS A0A2Z2MDW5/153-333 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus profundus; #=GS A0A170SL54/153-328 AC A0A170SL54 #=GS A0A170SL54/153-328 OS Thermococcus chitonophagus #=GS A0A170SL54/153-328 DE tRNA-(G10-N2) methyltransferase tRNA-(G10-N2) dimethyltransferase #=GS A0A170SL54/153-328 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus chitonophagus; #=GS A9V244/439-623 AC A9V244 #=GS A9V244/439-623 OS Monosiga brevicollis #=GS A9V244/439-623 DE Predicted protein #=GS A9V244/439-623 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A0A0E3MEV0/141-314 AC A0A0E3MEV0 #=GS A0A0E3MEV0/141-314 OS Saccharolobus solfataricus #=GS A0A0E3MEV0/141-314 DE RNA methyltransferase #=GS A0A0E3MEV0/141-314 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS D0KU04/141-314 AC D0KU04 #=GS D0KU04/141-314 OS Saccharolobus solfataricus 98/2 #=GS D0KU04/141-314 DE Putative RNA methylase #=GS D0KU04/141-314 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS C3N553/139-312 AC C3N553 #=GS C3N553/139-312 OS Sulfolobus islandicus M.16.27 #=GS C3N553/139-312 DE Putative RNA methylase #=GS C3N553/139-312 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C4KGQ6/139-312 AC C4KGQ6 #=GS C4KGQ6/139-312 OS Sulfolobus islandicus M.16.4 #=GS C4KGQ6/139-312 DE Putative RNA methylase #=GS C4KGQ6/139-312 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS I6UX97/154-329 AC I6UX97 #=GS I6UX97/154-329 OS Pyrococcus furiosus COM1 #=GS I6UX97/154-329 DE Uncharacterized protein #=GS I6UX97/154-329 DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus; Pyrococcus furiosus; #=GF SQ 25 Q58120/177-350 RPHLRKYFHPGCMLPKLARAMVNLARVKEGDIVLDPFCGTGGFLIEAGLI--GAKLIGCDIDWRMASGTLINLEEYNLL--DKVIKVKRLDAKYVKEFLNELNIEKVDAIVTDPPYGISTAKK-----GEIEKILETLPEVIKDNGYFVFAYPKKIEL--------DMELEGLYKVYIHKGLIRHIHVYKK------- O58076/154-329 KADRRPFSRPIALPPRIARAMVNLTK--ATREVLDPFMGTGGMLIEAGLI--GLKVYGLDIREDMVEGAKINLEYYGI----RDYVVKVGDATKIEEV---FPGKTFEAVATDPPYGNSTTLP-MDRNELYKRSLESIHSVLE--GRLAIAFPADFDA-RDVAESIGFKVLGRFYQRVHSSLSRYFYVMEV------- Q8TU64/172-352 --QNKPFFHPGVLMPRVARALTNLSEIKTGELFLDPFCGTAGILVEAGLV--GARVIGIDAQEKLVLGAHMNLEAYEL-----DYLLMEGDACRIP-----LKDSTINAVVTDPPYGRSAAILAGSLEELYSGALEEIHRVLKPGGIAVVVSDKAS---FEYGEKAGLKVLEIYVQRVHRSLTRIITIFRKDMEQNYS Q8ZWT1/70-224 IAR-----SVKTLDYITARTMVNLARVVRGSWVWEPFVGTGAVAYEVERV--GGYVVGGDVDLKALDLARKNTSG----------DLVVADALYPP-----L-AKKFDAIVGDPPYGRLSKTE-REVRALLREFIETALSLVKSGGFIVFASPIYV----------DFPYLKSCTMYLHGGLYRVIYIV--------- A9A3X1/150-315 KRPKKAISQPHELDWKLTRAMINLVGLKKGETVCDPFCGTGTTLLEAESM--GIHGIGLDFDEKMVEITKKNLKENGY-----KSRVIHSDFQEIKNM-----ADEFDGIVTDFPYGKNTKTS-----EKPEEIIKKFVTIVPKRKKMAIMYKKELGD------KLKLKGLKKYQIYRHKSLTRTILIK--------- T1FSK6/254-408 --------KHIGLRSTIASIIASLCSLKVGMVVADVMCGYGTILVEAAMLCPGLILVGFDIDGEACNKMRDNIKESQRFKNCCSIDVHQCDVRYIP-----LKNGSVDRVVCDLPFGLKHDRT-----CSVEDILISVHKILKVGGRCVLLCGANMSN--------------KFSKVVHD-------IFQCVL--D-- B1L6X4/131-305 --SARPYAHPASMRPTLARAMVNLARTRGGDLVLDPFLGVGGIALEILSV--GARLIGVDINEKLVIQAKNNLMTYGFL---EGYELRVGDALSLE-----L-GVRVDRIVTDPPYGRMSSSP-YAPRELASKFISKVPDYLRRGGWISISLPKEFLD-RRDFEDAGIDIVNFFDLREHRSLVRRIWVGK-------- Q97Z87/141-314 -HEKKPFSQSGTMNPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--NYECIGSDLDKAMLQKTKINLNYFNY-----YCSLLFSSATNLP-------FRQITSIATDPPYGRSTKNKGAELTQLYEEFFSSASETLTKGGFLVFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ Q5JID5/153-331 KAHHRPFFRPISLHPRVSRALVNLTK--ATREILDPFMGAGGILIEAGLL--GLRVYGVDIRPEMVEGAETNLKHYGV----RDYTLKLGDATRLEDL---FPDKKFEAVATDPPYGTAATLAGRKRDELYRKALRSIYNVLEDGGRLAIAFPTDFNG-KAEAEAVGFRTLGRYYQRVHKSLERYFYVFEK------- A9V3Y6/276-431 VEE--------GLRAGVGVTMALLARLEPGDIVVDPMAGRGSLLAEAARMFPDAHYLGMDMTNNQLRRMAQNFHVSRS---GASFDVLTASVTANP----CLRPGSVDAILCDLPYGRMYGSQ-EANRELYPRALATMASLLRKGGRAVFITAKDQQILLEESASTGFHA--------------------------YW A0A087RLK1/150-315 KRPKKAVSQPHELDWKLTRAMINLIGLKKGDTVCDPFCGTGTTLLEAESM--GIHGIGLDFDEKMVEITKKNLKENGY-----KSKVFHSDFQEIKNI-----SNKFDGVVTDFPYGKNTKTS-----ENSEEIIKRFVTIMPKRKKMAIMYKKEFGD------NLKLKGLKKYQIYRHKSLTRTILIK--------- Q9HN57/1-161 ------------MDPLLARAACNLARVTPGDRVLDPMCGTGGVLIEAGLL--GAHPIGTDAQAKMAAGARRNLTHYVD-----DATTGRADATALP-----LPSDSIDAAVLDAPYGRQSKIATHDLADLVGGALDELARVTA--GRCVLVADRDW---RAEATAAGWTVDARFQRRVHRSLVRHVLVLA-------- C3MYF9/139-312 -HEKKPFSQSGTMSPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--KYDCIGSDLDKTMLQKTKTNLNYFNY-----DCNLLFSSATNLP-------FHHITSIATDPPYGRSTKNKGAELMQLYEEFFSSASETLTKGGFLAFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ Q9UY84/153-329 KADRRPFSRPIALPPRIARAMVNLTR--ATREILDPFMGTGGMLIEAGLM--GLKVYGIDIREDMVEGAKINLEYYGV----KDYVVKVGDATKIKEA---FPGKTFEAIATDPPYGTSTTLP-MDRDELYKRALESMYSVLE--GRLAIAFPSDFDA-LDVAETIGFKVIGRFYQRVHSSLSRYFYIMEAR------ Q8U3Q6/154-329 KADRRPFSRPIALPPRIARAMVNLTR--ATRELLDPFMGTGGMLIEAGLM--GLKVYGLDIREDMVEGAKINLEYYGI----KDYVVKVGDATRIKEA---FPGKTFEAIATDPPYGSSTTLS-MERDMLYKKALESMYEVLE--GYLSIAFPEDFDA-IDVAESIGFKVIDRFYQRVHSSLARYFYVMKV------- A0A0E3L3V2/172-347 --QNKPFFHPGVLMPRVARAITNLSGIKPGELFLDPFCGTAGILVEAGLM--GARVIGIDAQEKLVLGAHMNLEAYEL-----DYILMEGDACRIP-----LKDSTIDAVVTDPPYGRSAAILAGSLEELYSSALEEIHRVLKPGGIAVVVSDKTA---FEYGEKAGLKVLEIYVQRVHRSLTRIITIFQKDM----- A0A0E3NFT6/172-347 --QNKPFFHPGVLMPRVARAITNLSGIKPGELFLDPFCGTAGILVEAGLM--GARVIGIDAQEKLVLGAHMNLEAYEL-----DYILMEGDACRIP-----LKDSTIDAVVTDPPYGRSAAILAGSLEELYSSALEEIHRVLKPGGIAVVVSDKTA---FEYGEKAGLKVLEIYVQRVHRSLTRIITIFQKDM----- A0A2Z2MDW5/153-333 KAHHRPFFRPISLHPRFSRALVNLTK--AKREILDPFMGAGGILIEAGLL--GLKVYGVDIRPEMVEGAETNLRNYGV----RDYTLELGDATRLEEL---FPNKKFEAVATDPPYGTAATLAGRKRDELYRKALRSIYNVLEDGGRLAIAFPIEFDG-KGEAEAVGFRTVGMYYQRVHKSLERYFYVFEKAR----- A0A170SL54/153-328 KADRRPFSRPIALPPRIARAMVNLTR--ATRELLDPFMGTGGMLIEAGLM--GLKVYGIDIREDMVEGAKINLEHYGV----KDYVVKVGDATRIKEV---FPGKTFEAIATDPPYGTSTTLP-MDRDELYRRALESMYEVLE--GYLSIAFPADFDA-IDVAESIGFKVLDRFYQRVHSSLSRYFYVMKT------- A9V244/439-623 VDRHRTEQGYSSLQTSVAAGLGRIARPWPNEVCLDPMCGAMTIAVETVTEFPDVTFLNSDIDRESLATGKANVNACLPPSAQARILSFYASARHLP-----LGVGAVDRVVCDMPWGKRCSKP-RLMRKLYPLLLVEWARVVRPGGRAYLLTMMRKCMEMHLTTSTNWQQLDRRQCNV-GGIKAYLYTLERT------ A0A0E3MEV0/141-314 -HEKKPFSQSGTMNPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--NYECIGSDLDKAMLQKTKINLNYFNY-----YCSLLFSSATNLP-------FRQITSIATDPPYGRSTKNKGAELTQLYEEFFSSASETLTKGGFLVFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ D0KU04/141-314 -HEKKPFSQSGTMNPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--NYECIGSDLDKAMLQKTKINLNYFNY-----YCSLLFSSATNLP-------FRQITSIATDPPYGRSTKNKGAELTQLYEEFFSSASETLTKGGFLVFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ C3N553/139-312 -HEKKPFSQSGTMSPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--KYDCIGSDLDKTMLQKTKTNLNYFNY-----DCNLLFSSATNLP-------FHHITSIATDPPYGRSTKNKGAELMQLYEEFFSSASETLTKGGFLAFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ C4KGQ6/139-312 -HEKKPFSQSGTMSPETSRLLVNLSR--PKKEVLDPFVGTGSILIEARWL--KYDCIGSDLDKTMLQKTKTNLNYFNY-----DCNLLFSSATNLP-------FHHITSIATDPPYGRSTKNKGAELMQLYEEFFSSASETLTKGGFLAFATDSRFNF-IDKLKENSFIIKGLHYLYSHKSLTRAIYVVQKK------ I6UX97/154-329 KADRRPFSRPIALPPRIARAMVNLTR--ATRELLDPFMGTGGMLIEAGLM--GLKVYGLDIREDMVEGAKINLEYYGI----KDYVVKVGDATRIKEA---FPGKTFEAIATDPPYGSSTTLS-MERDMLYKKALESMYEVLE--GYLSIAFPEDFDA-IDVAESIGFKVIDRFYQRVHSSLARYFYVMKV------- #=GC scorecons 123244334433735345655578451144435688649675575974350053335839443455345539743433000003335334664354000003123355565695989444433122224654446343345642473445534344210221222244333334334474563624463320000000 #=GC scorecons_70 ____________*_____*___**__________***_*_*__*_**__________*_*___________**__________________*_________________*__*_***____________*___________*___*________________________________*__*_*______________ #=GC scorecons_80 _______________________*__________**__*____*_**__________*_*___________*________________________________________*_***____________________________*____________________________________________________ #=GC scorecons_90 _______________________*__________**__*______*___________*_*___________*________________________________________*_*_*_________________________________________________________________________________ //