# STOCKHOLM 1.0 #=GF ID 3.40.50.140/FF/000008 #=GF DE DNA topoisomerase 1A #=GF AC 3.40.50.140/FF/000008 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 37.049 #=GS Q38C52/9-189 AC Q38C52 #=GS Q38C52/9-189 OS Trypanosoma brucei brucei TREU927 #=GS Q38C52/9-189 DE DNA topoisomerase IA, putative #=GS Q38C52/9-189 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38C52/9-189 DR GO; GO:0003677; GO:0003917; GO:0005737; GO:0006265; GO:0006304; #=GS Q4QCK3/9-188 AC Q4QCK3 #=GS Q4QCK3/9-188 OS Leishmania major #=GS Q4QCK3/9-188 DE DNA topoisomerase 1A #=GS Q4QCK3/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4QCK3/9-188 DR GO; GO:0005737; #=GS A4HBL0/9-188 AC A4HBL0 #=GS A4HBL0/9-188 OS Leishmania braziliensis #=GS A4HBL0/9-188 DE DNA topoisomerase 1A #=GS A4HBL0/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A4HZ99/9-188 AC A4HZ99 #=GS A4HZ99/9-188 OS Leishmania infantum #=GS A4HZ99/9-188 DE DNA topoisomerase 1A #=GS A4HZ99/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A0A088RPT5/9-188 AC A0A088RPT5 #=GS A0A088RPT5/9-188 OS Leishmania panamensis #=GS A0A088RPT5/9-188 DE DNA topoisomerase 1A #=GS A0A088RPT5/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS E9AUX9/9-188 AC E9AUX9 #=GS E9AUX9/9-188 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AUX9/9-188 DE DNA topoisomerase 1A #=GS E9AUX9/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A1E1IVQ2/9-188 AC A0A1E1IVQ2 #=GS A0A1E1IVQ2/9-188 OS Leishmania guyanensis #=GS A0A1E1IVQ2/9-188 DE Putative DNA topoisomerase 1A #=GS A0A1E1IVQ2/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; #=GS E9BF03/9-188 AC E9BF03 #=GS E9BF03/9-188 OS Leishmania donovani BPK282A1 #=GS E9BF03/9-188 DE DNA topoisomerase 1A #=GS E9BF03/9-188 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GF SQ 8 Q38C52/9-189 LEKLVIVESPNKVIKIEGLLSNPKVIPDWSFKQGHLKCVGIGAEKAVAMATTGHFMALKEITWITHPLPPSSAGGKPQEYDGEAFPSSGTLAEYTLEWEPLPGRRIQETLERYIEGKVENVSEIILATDPDREGELIAVHALQTIKRLYPKLKVPFSRAYMHSITEDGIRKAMKER----SLNIC- Q4QCK3/9-188 LEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASG------VTAADFPANGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPQLNAPFTRAYMHSITADGIRRAMEERHEAFDYNLAN A4HBL0/9-188 FEKLVIVESPNKVIKVEGLLSDPKVIPDWSFSNSKLRTISTGPEKAIAMATTGHFMSLKELTWSPQLSRPAPG------VTATDFPAKGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPKLSVPFTRAYMHSITADGIRRAMAERHEAFDYNLAN A4HZ99/9-188 LEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASR------VTSADFPSNGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRSMFPQLNVPFTRAYMHSITAEGIRRAMEERHEAFDYNLAN A0A088RPT5/9-188 FEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRTISTGPEKAIAMATTGHFMSLKELTWSPQLSSPAPG------VTATDFPAKGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPKLSVPFTRAYMHSITADGIRRAMAERHEAFDYNLAN E9AUX9/9-188 LEKLVIVESPNKVIKVEGLLSDPKVIPDWSFSNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQPSSPASG------VTAADFPANGLVVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPQLNVPFTRAYMHSITAEGIRRAMEERREAFDYNLAN A0A1E1IVQ2/9-188 FEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRTISTGPEKAIAMATTGHFMSLKELTWSPQLSSPAPG------VTATDFPAKGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPKLSVPFTRAYMHSITADGIRRAMAERHEAFDYNLAN E9BF03/9-188 LEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASR------VTAADFPSNGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRSMFPQLNVPFTRAYMHSITAEGIRRAMEERHETFDYNLAN #=GC scorecons 699999999999999699999699999999945559646559699969999999995999699556444956400000045545995495855759999569999996965699959569659996999999999999999455966679694799599999999579996994993333559653 #=GC scorecons_70 *********************_*********____**_*__***************_***_**__*___*_*____________**__*_*__*_****__********___***_*_**__***_***************___******_*_***_********_*******_**______*___ #=GC scorecons_80 _**************_*****_*********____*_____*_***_*********_***_**______*______________**__*_*__*_****__******_*___***_*__*__***_***************___*___**_*_***_********_****_**_**______*___ #=GC scorecons_90 _**************_*****_*********____*_____*_***_*********_***_**______*______________**__*______****__******_*___***_*__*__***_***************___*____*_*__**_********__***_**_**______*___ //