# STOCKHOLM 1.0
#=GF ID 3.40.50.140/FF/000006
#=GF DE DNA topoisomerase I
#=GF AC 3.40.50.140/FF/000006
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 66.319
#=GS Q59046/1-155      AC Q59046
#=GS Q59046/1-155      OS Methanocaldococcus jannaschii DSM 2661
#=GS Q59046/1-155      DE DNA topoisomerase 1
#=GS Q59046/1-155      DR ORG; Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; Methanocaldococcus jannaschii; 
#=GS Q59046/1-155      DR EC; 5.6.2.2; 
#=GS Q97ZJ8/6-156      AC Q97ZJ8
#=GS Q97ZJ8/6-156      OS Saccharolobus solfataricus P2
#=GS Q97ZJ8/6-156      DE DNA topoisomerase I family A (TopA)
#=GS Q97ZJ8/6-156      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS Q5JE24/1-154      AC Q5JE24
#=GS Q5JE24/1-154      OS Thermococcus kodakarensis KOD1
#=GS Q5JE24/1-154      DE DNA topoisomerase 1
#=GS Q5JE24/1-154      DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus kodakarensis; 
#=GS C3MPU5/6-163      AC C3MPU5
#=GS C3MPU5/6-163      OS Sulfolobus islandicus L.S.2.15
#=GS C3MPU5/6-163      DE DNA topoisomerase I
#=GS C3MPU5/6-163      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; 
#=GS A0A2Z2MQR2/1-154  AC A0A2Z2MQR2
#=GS A0A2Z2MQR2/1-154  OS Thermococcus barossii
#=GS A0A2Z2MQR2/1-154  DE DNA topoisomerase 1
#=GS A0A2Z2MQR2/1-154  DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus barossii; 
#=GS A0A2Z2M9W5/1-154  AC A0A2Z2M9W5
#=GS A0A2Z2M9W5/1-154  OS Thermococcus gorgonarius
#=GS A0A2Z2M9W5/1-154  DE DNA topoisomerase 1
#=GS A0A2Z2M9W5/1-154  DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus gorgonarius; 
#=GS H3ZKS6/1-154      AC H3ZKS6
#=GS H3ZKS6/1-154      OS Thermococcus litoralis DSM 5473
#=GS H3ZKS6/1-154      DE Uncharacterized protein
#=GS H3ZKS6/1-154      DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus litoralis; 
#=GS D0KTN2/6-156      AC D0KTN2
#=GS D0KTN2/6-156      OS Saccharolobus solfataricus 98/2
#=GS D0KTN2/6-156      DE DNA topoisomerase I
#=GS D0KTN2/6-156      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS A0A0E3JUC3/6-156  AC A0A0E3JUC3
#=GS A0A0E3JUC3/6-156  OS Saccharolobus solfataricus
#=GS A0A0E3JUC3/6-156  DE DNA topoisomerase I
#=GS A0A0E3JUC3/6-156  DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS D2PJZ0/6-163      AC D2PJZ0
#=GS D2PJZ0/6-163      OS Sulfolobus islandicus L.D.8.5
#=GS D2PJZ0/6-163      DE DNA topoisomerase I
#=GS D2PJZ0/6-163      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; 
#=GF SQ 10
Q59046/1-155              MAEIMTALIICEKPSVAKKIANALG--KAKKKSIDGVPYYELE-RDGKKIIVASAVGHLFTLVEKENKEFGFYPVFDIKWVPASV-DKGKEYVNKYIKALKKLSKDADEFYIATDWDIEGELIGYHALKYCCGRE--KAKRMRFSSLTKKEIVRAFENPDE-------
Q97ZJ8/6-156              V--NNYYLIIAEKSKAAKKIAEALSE-KPILCRKYNVSYWIIKDHNSSKYVIVPAAGHLFGLKGES----G-FPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKNLGDIK--KAKRMKFSALTKSDILSAFRNISA-------
Q5JE24/1-154              ----MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVSYYEFT-RDGKKVIVAPAVGHLFSLAPKT-KTYG-YPVFDIEWVPVYVAEKGKSYAKDYIKALATLAKQADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLKAWYNMEP-------
C3MPU5/6-163              V--NNYYLIIAEKSKAAKKIAEALSE-KPILCRKYNVNYWIIKDHDNNKYVIVPAAGHLFGLQGKS----G-FPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKYLGDTK--KAKRMKFSALTKSDILLAFRNVSTLDYDMIN
A0A2Z2MQR2/1-154          ----MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVPYYEFT-RDGKRIIVAPAVGHLFSLAPKT-KTYG-YPVFDIEWVPVYVAEKGKSYAKDYIKALATLAKRADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLRAWYNLEP-------
A0A2Z2M9W5/1-154          ----MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVSYYEFT-RDGKKIIVAPAVGHLFSLAPKT-KTYG-YPVFDIEWVPVYVAEKGKSYAKDYIKALATLAKKADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDILKAWYNLEP-------
H3ZKS6/1-154              ----MTTLIIAEKPNVARKIAYALAEKKPIRKTIGKVPYYELT-RDGKKIIVAPAVGHLFSLAPKE-KTYG-YPVFDIEWVPVYVAEKGKSYAKDYIKALRELAKRADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLRAWYNLEP-------
D0KTN2/6-156              V--NNYYLIIAEKSKAAKKIAEALSE-KPILCRKYNVSYWIIKDHNSSKYVIVPAAGHLFGLKGES----G-FPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKNLGDIK--KAKRMKFSALTKSDILSAFRNISA-------
A0A0E3JUC3/6-156          V--NNYYLIIAEKSKAAKKIAEALSE-KPILCRKYNVSYWIIKDHNSSKYVIVPAAGHLFGLKGES----G-FPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKNLGDIK--KAKRMKFSALTKSDILSAFRNISA-------
D2PJZ0/6-163              V--NNYYLIIAEKSKAAKKIAEALSE-KPILCRKYNVNYWIIKDHDNNKYVIVPAAGHLFGLQGKS----G-FPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKYLGDTK--KAKRMKFSALTKSDILLAFRNVSTLDYDMIN
#=GC scorecons            200253499979965697999399560975444435959545416654847767969999593464021190799795694954547955495759565644969394695497979699579994569645645119999989979995867395494440000000
#=GC scorecons_70         _______******___*****_**_*_**_______*_*_____**__*_**_**_****_*__*_____*_*****__*_*____**___*_*_*_*_*__*_*_*__*__*****_**_****__**________************_***_*__*__________
#=GC scorecons_80         _______******___*_***_**___**_______*_*_________*____**_****_*________*_*****__*_*_____*___*_*_*______*_*_*__*__*****_**_****___*________************_*_*_*__*__________
#=GC scorecons_90         _______***_**___*_***_**___*________*_*_________*_____*_****_*________*__**_*__*_*_____*___*___*______*_*_*__*__*_*_*_**__***___*________*****_**_***_____*__*__________
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