# STOCKHOLM 1.0
#=GF ID 3.40.50.12780/FF/000058
#=GF DE Acetyl-coenzyme A synthetase
#=GF AC 3.40.50.12780/FF/000058
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 65.635
#=GS A4YDT1/11-444      AC A4YDT1
#=GS A4YDT1/11-444      OS Metallosphaera sedula DSM 5348
#=GS A4YDT1/11-444      DE 4-hydroxybutyrate--CoA ligase 1
#=GS A4YDT1/11-444      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Metallosphaera; Metallosphaera sedula; 
#=GS A4YDT1/11-444      DR GO; GO:0003987; GO:0047760; GO:0050218; 
#=GS A4YDT1/11-444      DR EC; 6.2.1.1; 6.2.1.17; 6.2.1.2; 6.2.1.40; 
#=GS Q89N84/8-440       AC Q89N84
#=GS Q89N84/8-440       OS Bradyrhizobium diazoefficiens USDA 110
#=GS Q89N84/8-440       DE Blr3958 protein
#=GS Q89N84/8-440       DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; 
#=GS Q9Z5A7/14-442      AC Q9Z5A7
#=GS Q9Z5A7/14-442      OS Streptomyces coelicolor A3(2)
#=GS Q9Z5A7/14-442      DE Putative acetyl-coenzyme A synthetase
#=GS Q9Z5A7/14-442      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group; Streptomyces coelicolor; 
#=GS I0G9N9/8-440       AC I0G9N9
#=GS I0G9N9/8-440       OS Bradyrhizobium sp. S23321
#=GS I0G9N9/8-440       DE Putative acetyl-coenzyme A synthetase
#=GS I0G9N9/8-440       DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium sp. S23321; 
#=GS G7DJS3/9-439       AC G7DJS3
#=GS G7DJS3/9-439       OS Bradyrhizobium japonicum USDA 6
#=GS G7DJS3/9-439       DE Acetyl-coenzyme A synthetase
#=GS G7DJS3/9-439       DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium japonicum; 
#=GS A0A429NKZ1/14-441  AC A0A429NKZ1
#=GS A0A429NKZ1/14-441  OS Streptomyces sp. WAC08401
#=GS A0A429NKZ1/14-441  DE AMP-dependent synthetase
#=GS A0A429NKZ1/14-441  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. WAC08401; 
#=GS A0A3Q8VRR2/13-442  AC A0A3Q8VRR2
#=GS A0A3Q8VRR2/13-442  OS Streptomyces sp. KPB2
#=GS A0A3Q8VRR2/13-442  DE AMP-dependent synthetase
#=GS A0A3Q8VRR2/13-442  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. KPB2; 
#=GS A0A0K2B123/14-441  AC A0A0K2B123
#=GS A0A0K2B123/14-441  OS Streptomyces ambofaciens ATCC 23877
#=GS A0A0K2B123/14-441  DE Acetyl-coenzyme A synthetase
#=GS A0A0K2B123/14-441  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces ambofaciens; 
#=GS A0A088E5G6/11-444  AC A0A088E5G6
#=GS A0A088E5G6/11-444  OS Metallosphaera sedula
#=GS A0A088E5G6/11-444  DE AMP-dependent synthetase and ligase
#=GS A0A088E5G6/11-444  DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Metallosphaera; Metallosphaera sedula; 
#=GS A0A088E5G6/11-444  DR EC; 6.2.1.1; 6.2.1.17; 6.2.1.2; 6.2.1.40; 
#=GS A0A2A6N280/8-440   AC A0A2A6N280
#=GS A0A2A6N280/8-440   OS Bradyrhizobium diazoefficiens
#=GS A0A2A6N280/8-440   DE AMP-dependent synthetase
#=GS A0A2A6N280/8-440   DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; 
#=GS A0A0E4G0U0/48-460  AC A0A0E4G0U0
#=GS A0A0E4G0U0/48-460  OS Bradyrhizobium diazoefficiens
#=GS A0A0E4G0U0/48-460  DE Putative acetyl-coenzyme A synthetase
#=GS A0A0E4G0U0/48-460  DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; 
#=GF SQ 11
A4YDT1/11-444              --FIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFE--DIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLI-DGKRETWNSLEDESSNAEP----EDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLD-DEGKEITKP-YEVGHITVKL-NPRPIGLFLGYSDE-KKNMESFREGYYYTGDKAYFDEEGYFYFVGR---
Q89N84/8-440               RAFL----LQHRTDYEAAVKGFRWPDPTPFNWALDWFDAELAANAESKDRPALWIVDAAQDRQTKLSFAALSRRSNQVANFLRAQGLRRGDHLLLLLGNVVPLWETMLAAIKLGVVVIPATTLLTADELRDRLDRGKAKAVVAAQDQVAKFAS-LGAENVVRIVV-GAASDGWLAYDEAAEAPDSFVPDGPTHADDPMLLYFTSGTTAKPKLVLHSQRSYPVGHLSTMYWIGLKPGDVHLNISSPGWAKHAWSCFFAPWNAGATVFVVNQP-RFDAKALLATIGRCGVTTLCAPPTVWRLFIQENLASFKVA-LREVCGAGEPLNPEVIDQVQAAWGLTIRDGYGQTETTALAGNSPGQNIKVGSMGRPLPGYRVQVSD-ADG----NP-AKEGEVTLVLGANRPAGLMQGYQGD-DGKLSGAEGALYRSGDVVFEDEDGYLTFVGRS--
Q9Z5A7/14-442              --FL----LEHREDYTAAYEGFRWPRPANFNWALDWFD----VVAEGNGRTALHIVE-EDGREVRVSFAEMSARSNRVANRLREWGVGPEDRILVMLGNQAELWETALAAMKLRAVVIPATTLLGPADLRDRVDRGRVGHVIARAEDTGKFDD-VPGHYTRVAVGGATPAAGWRAYEDVYGASDTFTPDGPTAADDPLMLYFTSGTTARPKLVEHTHVSYPVGHLATMYWIGLKPGDVHLNISSPGWAKHAWSNLFAPWNAEATVFLYNYT-RFDATRLMAEMDRAGVTTFCAPPTVWRMLIQADLTRLATP-PREVVAAGEPLNPEVIEQVRRLWGRTIRDGFGQTETAVQVSNSPGQVLKTGSMGRPSPGYRVELLDPVTG----APGAAEGEIALDL-SDHPVGLMTGYHGDPDRTAEAMAGGYYRTGDIGARDEDGYLTYVGRA--
I0G9N9/8-440               RAFL----LQHRTDYETAVKDFRWPDPVPFNWALDWFDAELAANAESKDRPALWIVDAAQDKQTKLSFAALSRRSNQVADFLRAQGLKRGDHLLLLLGNVVPLWETMLAAMKLGVVVIPATTLLTADELRDRLDRGKAKAVVAAQDQVAKFAS-LGTENVVRIVV-GAGSDGWLGYDEAAKASESFTPDGPTNADDPMLLYFTSGTTAKPKLVLHSQRSYPVGHLSTMYWIGLKPGDVHLNISSPGWAKHAWSCFFAPWNAGATVFVLNQP-RFDAKALLATIGRCGVTTLCAPPTVWRLFIQENLASFKVA-LREVCGAGEPLNPEVIDQVKAAWGLTIRDGYGQTETTALAGNSPGQKIKVGSMGRPLPGYRVQVSD-ADG----HP-AKEGEVTLVLGANRPAGLMQGYQTD-DGKLSGAEGALYRSGDVVFEDEDGYLTFVGRS--
G7DJS3/9-439               -AFL----LKHRTDYETAVKDFRWPDPVPFNWALDWFD-ELAKDADAKDRPALWIVDAAQDKQTKLSFAALSQRSNQVANFLRAQGLKRGDHLLLLLGNVVPLWETMLAAMKLGVVVIPATTLLTADELRDRLDRGKAKAVVAAQDQVAKFAS-LGAENIVRIVV-GAASDGWLAYDEATKAAESFTADGPTNADDPMLLYFTSGTTAKPKLVRHSQRSYPVGHLSTMYWIGLKPGDVHLNISSPGWAKHAWSCFFAPWNAGATVFVVNQP-RFDAKGLLATIGRCGVTTLCAPPTVWRLFIQENLASFKVS-LREVCGAGEPLNPEVIDQVQAAWGLTIRDGYGQTETTALAGNSPGQKIKVGSMGRPLPGYRVQVSD-ADG----HP-AKEGEVALVLGTERPAGLMQGYQGD-DGKLSGAEGALYRSGDVVFADEDGYLTFVGRS--
A0A429NKZ1/14-441          --FL----LEHREDYTAAYEGFRWPRPEHFNWALDWFD----AIADGNGRTALHIVE-EDGSEVRVSFAEMSARSNRVANRLREWGVGPEDRILVMLGNQAELWETALAAMKLRAVVIPATPLLGPADLRDRVDRGRVRHVIVRAEDTGKFAD-VPGDYTRIAVG-GTGEAGWRPYQEVYTASDAFTPDGPTAADDPLMLYFTSGTTARPKLVEHTHVSYPVGHLATMYWIGLKPGDVHLNISSPGWAKHAWSNLFAPWNAEATVFLYNYT-RFDAARLMAEMERAGVTTFCAPPTVWRMLIQADLAQLATP-PREVVAAGEPLNPEVIEQVRRVWGRTIRDGFGQTETAVQVSNSPGQVLKTGSMGRPSPGYRVELLDPVTG----APGATEGEIALDL-SARPVGLMTGYHGDPDRTAEAMAGGYYRTGDIGARDEDGYLTYVGRA--
A0A3Q8VRR2/13-442          -DFL----LEHREDYTAAYEGFRWPRPEHFNWALDWFD----VIAEGNDRPALHIVE-EDGREVRVSFAEMSARSNRVANRLREWGVGPEDRILVMLGNQVELWETALAAMKLRAVVIPATTLLGPADLRDRVDRGRVKHVIVRAEDTGKFDD-VPGDYTRVAVGDGTTGPGWRPYEEVYGAPDAFTPDGPTAADDPLMLYFTSGTTARPKLVEHTHVSYPVGHLATMYWIGLTPGDVHLNISSPGWAKHAWSNLFAPWNAEATVFLYNYT-RFDATRLMSEMDRAGVTTFCAPPTVWRMLIQADLTRLATP-PREVVAAGEPLNPEVIEQVRRLWGRTIRDGFGQTETAVQVSNSPGQVLKTGSMGRPSPGYRVELIDPVTG----APGADEGEIALNL-ADRPVGLMTGYHGDPDRTAEAMAGGYYRTGDIGARDEDGYLTYVGRA--
A0A0K2B123/14-441          --FL----LEHREDYAAAYEGFTWPRPGNFNWALDWFD----VIAEGNRRTALHIVE-EDGSEVRVSFAEMSARSDRVANRLREWGVGPEDRILVMLGNQVELWETALAAMKLRAVVIPATPLLGPADLRDRVDRGRVGHVIVRAADTGKFAD-VPGDYTRVAVG-GTTAPGWSRYEDAYTASDVFIPDGPTTADDPLMLYFTSGTTARPKLVEHTHASYPIGHLATMYWIGLKPGDVHLNISSPGWAKHAWSNLFAPWNAEATVFLHNYT-RFDAGRLMAEMDRAAVTTFCAPPTVWRMLIQSDLSRLATP-PREVVAAGEPLNPEVIEQVRRAWGVTVRDGFGQTETAVQVSNSPGQVLKTGSMGRPSPGYRVELLDPVTG----APGADEGEIALDL-SESPVGLMTGYHGDPDRTAEAMAGGYYRTGDIGARDADGYLTYVGRA--
A0A088E5G6/11-444          --FIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFE--DIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLI-DGKRETWNSLEDESSNAEP----EDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLD-DEGKEITKP-YEVGHITVKL-NPRPIGLFLGYSDE-KKNMESFREGYYYTGDKAYFDEEGYFYFVGR---
A0A2A6N280/8-440           RAFL----LQHRTDYEAAVKGFRWPDPTPFNWALDWFDAELAANAESKDRPALWIVDAAQDRQTKLSFAALSRRSNQVANFLRAQGLRRGDHLLLLLGNVVPLWETMLAAIKLGVVVIPATTLLTADELRDRLDRGKAKAVVAAQDQVAKFAS-LGAENVVRIVV-GAASDGWLAYDEAAEAPDSFVPDGPTHADDPMLLYFTSGTTAKPKLVLHSQRSYPVGHLSTMYWIGLKPGDVHLNISSPGWAKHAWSCFFAPWNAGATVFVVNQP-RFDAKALLATIGRCGVTTLCAPPTVWRLFIQENLASFKVA-LREVCGAGEPLNPEVIDQVQAAWGLTIRDGYGQTETTALAGNSPGQNIKVGSMGRPLPGYRVQVSD-ADG----NP-AKEGEVTLVLGANRPAGLMQGYQGD-DGKLSGAEGALYRSGDVVFEDEDGYLTFVGRS--
A0A0E4G0U0/48-460          --------------------------SGPFNWALDWFDAELAANAESKDRPALWIVDAAQDRQTKLSFAALSRRSNQVANFLRAQGLKRGDHLLLLLGNVVPLWETMLAAMKLGVVVIPATTLLTADELRDRLDRGKAKAVVAAQDQVAKFAS-LGAENVVRIVV-GAASDGWLAYDEAAEAPDSFVPDGPTHADDPMLLYFTSGTTAKPKLVLHSQRSYPVGHLSTMYWIGLKPGDVHLNISSPGWAKHAWSCFFAPWNAGATVFVVNQP-RFDAKALLATIGRCGVTTLCAPPTVWRLFIQENLASFKVA-LREVCGAGEPLNPEVIDQVQAAWGLTIRDGYGQTETTALAGNSPGQNIKVGSMGRPLPGYRVQVSD-ADG----NP-AKEGEVTLVLGANRPAGLMQGYQGD-DGKLSGAEGALYRSGDVVFEDEDGYLTFVGRSDD
#=GC scorecons             007500004355354345453544545349996595970112346744476993557244646576975569359869663994496546945666665453596649966956496796675964577759566574457744434555654065434534464055344693466743365744244659367965559999999649959396449998966596657966569699969669999699946969556699964395407696456655556389966999996994696369446444069695599999999995555446659899579999966466959554594999979395967564904490000490545967663914379599649945706444554466595699444397799657999300
#=GC scorecons_70          __*__________________________****_*_**_______*___*_**___*_____*_****__**__****___**__**__**___**_______*_*_*****___*******_*___***_*_*__*___**________*___*________*_______**___**___*_*_____*_*_***____********_**_*_*___*****_*_*___****_******************_****__******__*___****___*____*_*************_**__**__*_____*_*__**********_______*_****_********__**_*____*_******_*_*_*_*_*___*_____*____*****_*___**_***_**__*_*_______*__*__**____******_****___
#=GC scorecons_80          __*__________________________***__*_**_______*___*_**___*_______*_**___*__**_*___**__*____*____________*___**__*___*_**__*_*___*_*_*____*___*_______________________________*__________________*__**____*******__**_*_*___*****___*___**____*_***_*__****_***__*_*____***___*___*_*___________***__*****_**__*___*________*_*__**********_________****_******_____*_*____*_******_*_*_*___*___*_____*____*_____*____*_**__**__*____________*__**____*****__****___
#=GC scorecons_90          _____________________________***__*_*______________**_____________*____*__**_*___**__*____*____________*___**__*___*__*____*_______*________________________________________*__________________*___*____*******__**_*_*___*****___*____*____*_***_*__****_***__*_*____***___*_____*____________**__*****_**__*___*________*_*__**********_________****__*****_____*_*____*_****_*_*_*_____*___*_____*____*_____*____*_**__**_______________*__**____*__**___***___
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