# STOCKHOLM 1.0
#=GF ID 3.40.50.1220/FF/000044
#=GF DE NAD-dependent histone deacetylase SIR2
#=GF AC 3.40.50.1220/FF/000044
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 43.914
#=GS 4iaoB02/167-200_253-293_381-492 AC P06700
#=GS 4iaoB02/167-200_253-293_381-492 OS Saccharomyces cerevisiae S288C
#=GS 4iaoB02/167-200_253-293_381-492 DE NAD-dependent histone deacetylase SIR2
#=GS 4iaoB02/167-200_253-293_381-492 DR CATH; 4iao; B:237-270; B:323-363; B:451-555; 
#=GS 4iaoB02/167-200_253-293_381-492 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4iaoB02/167-200_253-293_381-492 DR GO; GO:0000183; GO:0000784; GO:0001300; GO:0001302; GO:0005515; GO:0005677; GO:0005720; GO:0005724; GO:0005730; GO:0006303; GO:0006325; GO:0006333; GO:0006348; GO:0007062; GO:0008156; GO:0017136; GO:0030466; GO:0030869; GO:0032041; GO:0034398; GO:0045910; GO:0046969; GO:0046970; GO:0097695; GO:1904524; 
#=GS Q5AQ47/364-410_513-612      AC Q5AQ47
#=GS Q5AQ47/364-410_513-612      OS Candida albicans SC5314
#=GS Q5AQ47/364-410_513-612      DE NAD-dependent protein deacetylase HST1
#=GS Q5AQ47/364-410_513-612      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida albicans; 
#=GS Q5AQ47/364-410_513-612      DR GO; GO:0036166; 
#=GS 4iaoA02/167-200_253-293_381-492 AC P06700
#=GS 4iaoA02/167-200_253-293_381-492 OS Saccharomyces cerevisiae S288C
#=GS 4iaoA02/167-200_253-293_381-492 DE NAD-dependent histone deacetylase SIR2
#=GS 4iaoA02/167-200_253-293_381-492 DR CATH; 4iao; A:237-270; A:323-363; A:451-555; 
#=GS 4iaoA02/167-200_253-293_381-492 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4iaoA02/167-200_253-293_381-492 DR GO; GO:0000183; GO:0000784; GO:0001300; GO:0001302; GO:0005515; GO:0005677; GO:0005720; GO:0005724; GO:0005730; GO:0006303; GO:0006325; GO:0006333; GO:0006348; GO:0007062; GO:0008156; GO:0017136; GO:0030466; GO:0030869; GO:0032041; GO:0034398; GO:0045910; GO:0046969; GO:0046970; GO:0097695; GO:1904524; 
#=GS 2hjhB01/1-62_115-155_243-354 AC P06700
#=GS 2hjhB01/1-62_115-155_243-354 OS Saccharomyces cerevisiae S288C
#=GS 2hjhB01/1-62_115-155_243-354 DE NAD-dependent histone deacetylase SIR2
#=GS 2hjhB01/1-62_115-155_243-354 DR CATH; 2hjh; B:211-270; B:323-363; B:451-555; 
#=GS 2hjhB01/1-62_115-155_243-354 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 2hjhB01/1-62_115-155_243-354 DR GO; GO:0000183; GO:0000784; GO:0001300; GO:0001302; GO:0005515; GO:0005677; GO:0005720; GO:0005724; GO:0005730; GO:0006303; GO:0006325; GO:0006333; GO:0006348; GO:0007062; GO:0008156; GO:0017136; GO:0030466; GO:0030869; GO:0032041; GO:0034398; GO:0045910; GO:0046969; GO:0046970; GO:0097695; GO:1904524; 
#=GS 2hjhA01/1-62_115-155_243-354 AC P06700
#=GS 2hjhA01/1-62_115-155_243-354 OS Saccharomyces cerevisiae S288C
#=GS 2hjhA01/1-62_115-155_243-354 DE NAD-dependent histone deacetylase SIR2
#=GS 2hjhA01/1-62_115-155_243-354 DR CATH; 2hjh; A:210-270; A:323-363; A:451-556; 
#=GS 2hjhA01/1-62_115-155_243-354 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 2hjhA01/1-62_115-155_243-354 DR GO; GO:0000183; GO:0000784; GO:0001300; GO:0001302; GO:0005515; GO:0005677; GO:0005720; GO:0005724; GO:0005730; GO:0006303; GO:0006325; GO:0006333; GO:0006348; GO:0007062; GO:0008156; GO:0017136; GO:0030466; GO:0030869; GO:0032041; GO:0034398; GO:0045910; GO:0046969; GO:0046970; GO:0097695; GO:1904524; 
#=GS P06700/319-365_457-562      AC P06700
#=GS P06700/319-365_457-562      OS Saccharomyces cerevisiae S288C
#=GS P06700/319-365_457-562      DE NAD-dependent histone deacetylase SIR2
#=GS P06700/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P06700/319-365_457-562      DR GO; GO:0000183; GO:0000784; GO:0001300; GO:0001302; GO:0005515; GO:0005677; GO:0005720; GO:0005724; GO:0005730; GO:0006303; GO:0006325; GO:0006333; GO:0006348; GO:0007062; GO:0008156; GO:0017136; GO:0030466; GO:0030869; GO:0032041; GO:0034398; GO:0045910; GO:0046969; GO:0046970; GO:0097695; GO:1904524; 
#=GS J5S1E1/320-365_462-567      AC J5S1E1
#=GS J5S1E1/320-365_462-567      OS Saccharomyces kudriavzevii IFO 1802
#=GS J5S1E1/320-365_462-567      DE SIR2-like protein
#=GS J5S1E1/320-365_462-567      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces kudriavzevii; 
#=GS A0A0L8VWP1/319-365_457-562  AC A0A0L8VWP1
#=GS A0A0L8VWP1/319-365_457-562  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VWP1/319-365_457-562  DE SIR2p NAD+ dependent histone deacetylase of the Sirtuin family
#=GS A0A0L8VWP1/319-365_457-562  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS J8Q3Y8/319-365_462-567      AC J8Q3Y8
#=GS J8Q3Y8/319-365_462-567      OS Saccharomyces arboricola H-6
#=GS J8Q3Y8/319-365_462-567      DE Sir2p
#=GS J8Q3Y8/319-365_462-567      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces arboricola; 
#=GS H0GDU1/319-365_457-562      AC H0GDU1
#=GS H0GDU1/319-365_457-562      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GDU1/319-365_457-562      DE Sir2p
#=GS H0GDU1/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS A6ZXT3/320-365_457-562      AC A6ZXT3
#=GS A6ZXT3/320-365_457-562      OS Saccharomyces cerevisiae YJM789
#=GS A6ZXT3/320-365_457-562      DE Nuclear NAD-dependent deacetylase
#=GS A6ZXT3/320-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C8Z4M8/319-365_457-562      AC C8Z4M8
#=GS C8Z4M8/319-365_457-562      OS Saccharomyces cerevisiae EC1118
#=GS C8Z4M8/319-365_457-562      DE Sir2p
#=GS C8Z4M8/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS G2WCB9/320-365_457-562      AC G2WCB9
#=GS G2WCB9/320-365_457-562      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2WCB9/320-365_457-562      DE K7_Sir2p
#=GS G2WCB9/320-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LGU0/319-365_457-562      AC B3LGU0
#=GS B3LGU0/319-365_457-562      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LGU0/319-365_457-562      DE NAD-dependent histone deacetylase SIR2
#=GS B3LGU0/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1P5V5/319-365_457-562      AC N1P5V5
#=GS N1P5V5/319-365_457-562      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1P5V5/319-365_457-562      DE Sir2p
#=GS N1P5V5/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B5VFM5/319-365_457-562      AC B5VFM5
#=GS B5VFM5/319-365_457-562      OS Saccharomyces cerevisiae AWRI1631
#=GS B5VFM5/319-365_457-562      DE YDL042Cp-like protein
#=GS B5VFM5/319-365_457-562      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GF SQ 16
4iaoB02/167-200_253-293_381-492     ----------------------------RLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKSQEKDKGVYVVTSDEHPKTL
Q5AQ47/364-410_513-612              ----------------------------------------------------------NHIYSPLHSFIKLLQDKNKLLRNYTQNIDNLESYAGIHKENLIQCH----GINQDINKVDLVLVIGTSLKVAPVADIVGKIPEHIPQILLNKDPINHCQFDVSLLGYCDDVASYIANELGESWDLPHPDYNKIRGEK---NGENLSVQLLDS-----TL
4iaoA02/167-200_253-293_381-492     ----------------------------RLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKSQEKDKGVYVVTSDEHPKTL
2hjhB01/1-62_115-155_243-354        EDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGSPLHSFIKXLQXKGKLLRNYTQNIDNLESYAGISTDKLVQCNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNXVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAXVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
2hjhA01/1-62_115-155_243-354        EDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGSPLHSFIKXLQXKGKLLRNYTQNIDNLESYAGISTDKLVQCNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNXVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAXVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
P06700/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
J5S1E1/320-365_462-567              -----------------------------------------------------------NIYSPLHSFIKMLQAKGKLLRNYTQNIDNLESYAGISADKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPAHVPQVLINYDPVKHAEFDLSLLGYCDDVAAMVAQKCG--WTIPHKKWNDLKNKKFECREKDKGVYVVASDEHPGTL
A0A0L8VWP1/319-365_457-562          ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
J8Q3Y8/319-365_462-567              ----------------------------------------------------------ENLYSPLHSFIKMLQTKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILKCDLLICIGTSLKVAPVSEIVNMVPAHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCD--WAIPHKKWNELKNKKFECQEKDRGVYVITSDEHPRTL
H0GDU1/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
A6ZXT3/320-365_457-562              -----------------------------------------------------------NIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
C8Z4M8/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
G2WCB9/320-365_457-562              -----------------------------------------------------------NIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
B3LGU0/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
N1P5V5/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
B5VFM5/319-365_457-562              ----------------------------------------------------------EKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCH----GIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQKCG--WTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL
#=GC scorecons                      0000000000000000000000000000111111111111111111111111111111346499999999499297999999999999999999976879899611116977996779977799999999997899738969899897979987977997999999997973897768009679977797787766556777679777696666599
#=GC scorecons_70                   ____________________________________________________________*_********_**_*****************************______****************************_*********************************_******__****************__****************_**
#=GC scorecons_80                   ______________________________________________________________********_**_**********************_******______*****___****_***************_**_******************************_****_*__*_***_***_****_____***_*****_*_____**
#=GC scorecons_90                   ______________________________________________________________********_**_*_*******************____*_**______*__**___**___**********__**___*_*_**_*_*_**__*__**_********_*___*___*__*__**___*_______________*____*_____**
//