# STOCKHOLM 1.0
#=GF ID 3.40.430.10/FF/000011
#=GF DE Rib7p
#=GF AC 3.40.430.10/FF/000011
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 92.331
#=GS 4ha9B00/1-249     AC P33312
#=GS 4ha9B00/1-249     OS Saccharomyces cerevisiae S288C
#=GS 4ha9B00/1-249     DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS 4ha9B00/1-249     DR CATH; 4ha9; B:8-243; 
#=GS 4ha9B00/1-249     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4ha9B00/1-249     DR GO; GO:0008703; GO:0009231; 
#=GS 4ha9B00/1-249     DR EC; 1.1.1.302; 
#=GS Q9P7L3/2-251      AC Q9P7L3
#=GS Q9P7L3/2-251      OS Schizosaccharomyces pombe 972h-
#=GS Q9P7L3/2-251      DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS Q9P7L3/2-251      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS Q9P7L3/2-251      DR GO; GO:0005634; GO:0005829; GO:0008703; GO:0009231; 
#=GS Q9P7L3/2-251      DR EC; 1.1.1.302; 
#=GS Q58085/6-224      AC Q58085
#=GS Q58085/6-224      OS Methanocaldococcus jannaschii DSM 2661
#=GS Q58085/6-224      DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS Q58085/6-224      DR ORG; Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; Methanocaldococcus jannaschii; 
#=GS Q58085/6-224      DR GO; GO:0009231; GO:0016616; GO:0046983; GO:0050661; GO:0051287; 
#=GS Q58085/6-224      DR EC; 1.1.1.302; 
#=GS O66747/1-219      AC O66747
#=GS O66747/1-219      OS Aquifex aeolicus VF5
#=GS O66747/1-219      DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS O66747/1-219      DR ORG; Bacteria; Aquificae; Aquificae; Aquificales; Aquificaceae; Aquifex; Aquifex aeolicus; 
#=GS O66747/1-219      DR GO; GO:0009231; GO:0016616; GO:0046983; GO:0050661; 
#=GS O66747/1-219      DR EC; 1.1.1.302; 
#=GS 4ha9A00/1-249     AC P33312
#=GS 4ha9A00/1-249     OS Saccharomyces cerevisiae S288C
#=GS 4ha9A00/1-249     DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS 4ha9A00/1-249     DR CATH; 4ha9; A:8-242; 
#=GS 4ha9A00/1-249     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4ha9A00/1-249     DR GO; GO:0008703; GO:0009231; 
#=GS 4ha9A00/1-249     DR EC; 1.1.1.302; 
#=GS 4ha7B00/1-249     AC P33312
#=GS 4ha7B00/1-249     OS Saccharomyces cerevisiae S288C
#=GS 4ha7B00/1-249     DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS 4ha7B00/1-249     DR CATH; 4ha7; B:8-243; 
#=GS 4ha7B00/1-249     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4ha7B00/1-249     DR GO; GO:0008703; GO:0009231; 
#=GS 4ha7B00/1-249     DR EC; 1.1.1.302; 
#=GS 4ha7A00/1-249     AC P33312
#=GS 4ha7A00/1-249     OS Saccharomyces cerevisiae S288C
#=GS 4ha7A00/1-249     DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS 4ha7A00/1-249     DR CATH; 4ha7; A:8-242; 
#=GS 4ha7A00/1-249     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 4ha7A00/1-249     DR GO; GO:0008703; GO:0009231; 
#=GS 4ha7A00/1-249     DR EC; 1.1.1.302; 
#=GS P33312/1-244      AC P33312
#=GS P33312/1-244      OS Saccharomyces cerevisiae S288C
#=GS P33312/1-244      DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS P33312/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P33312/1-244      DR GO; GO:0008703; GO:0009231; 
#=GS P33312/1-244      DR EC; 1.1.1.302; 
#=GS Q6FU96/1-244      AC Q6FU96
#=GS Q6FU96/1-244      OS [Candida] glabrata CBS 138
#=GS Q6FU96/1-244      DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS Q6FU96/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces; [Candida] glabrata; 
#=GS Q6FU96/1-244      DR GO; GO:0009231; GO:0016616; GO:0046983; GO:0050661; 
#=GS Q6FU96/1-244      DR EC; 1.1.1.302; 
#=GS H0GCL5/1-244      AC H0GCL5
#=GS H0GCL5/1-244      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GCL5/1-244      DE Rib7p
#=GS H0GCL5/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS A0A0L8VUW7/1-244  AC A0A0L8VUW7
#=GS A0A0L8VUW7/1-244  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VUW7/1-244  DE RIB7p Diaminohydroxyphoshoribosylaminopyrimidine deaminase
#=GS A0A0L8VUW7/1-244  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS N1PAT9/1-244      AC N1PAT9
#=GS N1PAT9/1-244      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1PAT9/1-244      DE Rib7p
#=GS N1PAT9/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1PAT9/1-244      DR EC; 1.1.1.302; 
#=GS A0A0W0CZK9/1-244  AC A0A0W0CZK9
#=GS A0A0W0CZK9/1-244  OS [Candida] glabrata
#=GS A0A0W0CZK9/1-244  DE 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
#=GS A0A0W0CZK9/1-244  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces; [Candida] glabrata; 
#=GS A0A0W0CZK9/1-244  DR EC; 1.1.1.302; 
#=GS A6ZL95/1-244      AC A6ZL95
#=GS A6ZL95/1-244      OS Saccharomyces cerevisiae YJM789
#=GS A6ZL95/1-244      DE Diaminohydroxyphoshoribosylaminopyrimidine deaminase
#=GS A6ZL95/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS D3UEP7/1-244      AC D3UEP7
#=GS D3UEP7/1-244      OS Saccharomyces cerevisiae EC1118
#=GS D3UEP7/1-244      DE Rib7p
#=GS D3UEP7/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C7GUV1/1-244      AC C7GUV1
#=GS C7GUV1/1-244      OS Saccharomyces cerevisiae JAY291
#=GS C7GUV1/1-244      DE Rib7p
#=GS C7GUV1/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS G2W9F5/1-244      AC G2W9F5
#=GS G2W9F5/1-244      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2W9F5/1-244      DE K7_Rib7p
#=GS G2W9F5/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LN06/1-244      AC B3LN06
#=GS B3LN06/1-244      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LN06/1-244      DE 5-amino-6-(5-phosphoribosylamino)uracil reductase
#=GS B3LN06/1-244      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GF SQ 18
4ha9B00/1-249             GPLGSMSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
Q9P7L3/2-251              ----ESS------------QAYFPP--SANK---KHVLLTWAQSINGRIGYVVESPSLGQLRLSSKESFVMTHLLRTKFDGIMVGSRTAENDNPSLTAKLPDPA-NPDCLLPLNKQPIPIIVDSNLRLDYASLKVIRLARERLGKPPLIIVAPSIWQQVQHDSKLKEAVKLIQSVGGRCIIRNEDSPDSWSDYVALDKLLQN-GVNRIMVEGGAELLAKAFGSTDIDAYV-VTIVPKIFSCSNTTEIKNLNN-------LNLTTNSHWYPCGPDVIFTNYS---
Q58085/6-224              ----------------------------EKK---PYIISNVGMTLDGKLATINNDS-----RISCEEDLIRVHKIRANVDGIMVGIGTVLKDDPRLTVHK----------IKSDRNPVRIVVDSKLRVPLNARVLN-----KDAKTIIATTEDTNEEKEKK---IK----ILEDMGV-EVVKCGRGKVDLKK--LMDILYDK-GIKSILLEGGGT-LNWGMFKEGLVDEVSVYIAPKIFGGKEAPTYVDGEGFKTVDECVKLELKNFY-RLGEGIVLEFKVKK-
O66747/1-219              ----------------------------MER---PYVIIVSEVSVDGKLTLYRGASSKELMSLMDEEAYKYLHEIRAKVDGIMVGCETVRTDNPSLTVRY-----------AKGKNPVRIIPCSTANVPLDANVLN----TKEAPTIIATTERAPKERLEK---IK-------ELGA-EVIVVGDELVDFDK--LLPELYRR-GIKSLMVEGGAS-INWEFVRRRVVDEIRLIHLPVIVGGENVPTLVGGEGFKKLKNLLHLRLRSHF-VRGKQLITEWEV---
4ha9A00/1-249             GPLGSMSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
4ha7B00/1-249             GPLGSMSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
4ha7A00/1-249             GPLGSMSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
P33312/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
Q6FU96/1-244              -------MLRVRDDLPPFLKNYLPDGHRNGR---PFVTLTYAQSIDAKIAKQRGVRT----TISHIETKEMTHYLRYFHDGILIGSGTVLADDPGLNCKWIGPNNDPD-ESMEEKSPRPIILDPKLKWKYSGSKMEELCNQGMGKPPIVITTKTPKVKEAN---VEYMI---------ME-PDANDRISWKS--ILDTLRRNYDMKSVMIEGGSHVINQLLMCSDLIDSL-IVTIGSIYLGSEGVTVSPPDE-------VKLKDISWW-KGTSDVVMCSRLQN-
H0GCL5/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPDTKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPRT-------VNLKDMSWW-KGITDVVLCARLADD
A0A0L8VUW7/1-244          -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPDTKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-ILTIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
N1PAT9/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
A0A0W0CZK9/1-244          -------MLRVRDDLPPFLKNYLPDGHRNGR---PFVTLTYAQSIDAKIAKQRGVRT----TISHIETKEMTHYLRYFHDGILIGSGTVLADDPGLNCKWIGPNNDPD-ESMEEKSPRPIILDPKLKWKYSGSKMEELCNQGMGKPPIVITTKTPKVKEAN---VEYMI---------ME-PDANDRISWKS--ILDTLRRNYDMKSVMIEGGSHVINQLLMCSDLIDSL-IVTIGSIYLGSEGVTVSPPDE-------VKLKDISWW-KGTSDVVMCSRLQN-
A6ZL95/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPETKTMTHYLRHHHDGILIGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
D3UEP7/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPDTKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
C7GUV1/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPDTKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IITIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
G2W9F5/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRT----TISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-IVTIGSTFLGSSGTEISPPQT-------VNLKDMSWW-KGITDVVLCARLADD
B3LN06/1-244              -----MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSKGPGVRT----IISHPDTKTMTHYLRHHHDGILVGSGTVLADNPGLNCKW-GP--DP-----AANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQH---VDYAI---------CPINDTTKLVDWKK--LFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSL-ILTIGSTFLGSSGTEVSPPQT-------VNLKDMSWW-KGITDVVLCARLADD
#=GC scorecons            00000222222223332333343422224551117685664657676755334645400004674375445694694449996796697559695964640340034000003455946985656464455545643422363676576555445347555000653340000001004453444446656500655493542576767699964367446454666546064555466475455554444400000006595437460444466754355231
#=GC scorecons_70         __________________________________***______*_*_*_____*________**__*_____*_**___******_***__***_*__*_________________*__**_*___*_______*________***_*_________*______*_______________________*_________*_____*_********__**_____________*______*_*__________________*_*___*________**________
#=GC scorecons_80         __________________________________*_*______*_*_________________*__*_____*__*___***_**__**__*_*_*____________________*__**__________________________*__________________________________________________*_______*_*_***____*______________________*____________________*___*_________*________
#=GC scorecons_90         ________________________________________________________________________*__*___***__*__*___*_*_*____________________*__*______________________________________________________________________________*___________***________________________________________________*______________________
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