# STOCKHOLM 1.0
#=GF ID 3.40.1360.10/FF/000018
#=GF DE Type II DNA topoisomerase VI subunit A
#=GF AC 3.40.1360.10/FF/000018
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 88.037
#=GS E2RTV8/124-342     AC E2RTV8
#=GS E2RTV8/124-342     OS Giardia lamblia ATCC 50803
#=GS E2RTV8/124-342     DE Spo11 Type II DNA topoisomerase VI subunit A
#=GS E2RTV8/124-342     DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS A0A1U8QLS1/93-327  AC A0A1U8QLS1
#=GS A0A1U8QLS1/93-327  OS Aspergillus nidulans FGSC A4
#=GS A0A1U8QLS1/93-327  DE Uncharacterized protein
#=GS A0A1U8QLS1/93-327  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus nidulans; 
#=GS Q5ATX1/93-327      AC Q5ATX1
#=GS Q5ATX1/93-327      OS Aspergillus nidulans FGSC A4
#=GS Q5ATX1/93-327      DE Spo11 homologue spoA (Eurofung)
#=GS Q5ATX1/93-327      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus nidulans; 
#=GS B3S267/1-157       AC B3S267
#=GS B3S267/1-157       OS Trichoplax adhaerens
#=GS B3S267/1-157       DE Uncharacterized protein
#=GS B3S267/1-157       DR ORG; Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax; Trichoplax adhaerens; 
#=GS B7QAT2/46-264      AC B7QAT2
#=GS B7QAT2/46-264      OS Ixodes scapularis
#=GS B7QAT2/46-264      DE Topoisomerase 6 subunit A, putative
#=GS B7QAT2/46-264      DR ORG; Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes; Ixodes scapularis; 
#=GS A7E8A1/59-281      AC A7E8A1
#=GS A7E8A1/59-281      OS Sclerotinia sclerotiorum 1980 UF-70
#=GS A7E8A1/59-281      DE Uncharacterized protein
#=GS A7E8A1/59-281      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; Helotiales; Sclerotiniaceae; Sclerotinia; Sclerotinia sclerotiorum; 
#=GS Q0TYH8/84-298      AC Q0TYH8
#=GS Q0TYH8/84-298      OS Parastagonospora nodorum SN15
#=GS Q0TYH8/84-298      DE Uncharacterized protein
#=GS Q0TYH8/84-298      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae; Parastagonospora; Parastagonospora nodorum; 
#=GS Q86C20/124-342     AC Q86C20
#=GS Q86C20/124-342     OS Giardia intestinalis
#=GS Q86C20/124-342     DE Spo11
#=GS Q86C20/124-342     DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS V6TCN3/127-345     AC V6TCN3
#=GS V6TCN3/127-345     OS Giardia intestinalis
#=GS V6TCN3/127-345     DE Type II DNA topoisomerase VI subunit A
#=GS V6TCN3/127-345     DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GF SQ 9
E2RTV8/124-342             AKGLLLGNCTMVTQVGTVTASSLVAV-PISPH-FFYLQQIH-TDAQFVLVIEKDTVFEHLIDSYEAIKDRLGQSFMVI--------TGKGYPDAATRALVSFLD---------SCRIPIFGLADGDAHGMNILCTYAYGSASATRKSVV---PNHYIAPSLVPIGVFNSHIQRSS-----------KAIKGSRHCDPADLKLYDILITR--LTALG--RLEWANEVQNLAALGMQYELETIL--GQEGGLVSYVVETVV---------
A0A1U8QLS1/93-327          AKGLVAGYYRVTTVRDEVIDARESTEDCLIPR-VQDIADLDISDVKWILIIEKEAVFRRLVRNNFHNHTIVGKG-ILI--------TGKGYPDLATRSFVRRIFQSTFPRSTLTQAPPFYILADGDPDGIAIMSTYKYGSMAHTREN------ERLNLPCLQWLGLRISEIIGGL------ES---DADETLMSLTRRDRRKIGTMLKRSPIWAVDGPEAEWRVELQRMLILNVKAEIEILY--DRAGGLEGWIDRHMKTQ------G
Q5ATX1/93-327              AKGLVAGYYRVTTVRDEVIDARESTEDCLIPR-VQDIADLDISDVKWILIIEKEAVFRRLVRNNFHNHTIVGKG-ILI--------TGKGYPDLATRSFVRRIFQSTFPRSTLTQAPPFYILADGDPDGIAIMSTYKYGSMAHTREN------ERLNLPCLQWLGLRISEIIGGL------ES---DADETLMSLTRRDRRKIGTMLKRSPIWAVDGPEAEWRVELQRMLILNVKAEIEILY--DRAGGLEGWIDRHMKTQ------G
B3S267/1-157               ----MAGDFRFIMKSGHFLCGSFENKIQSIPL-VADIAGIE-STAKFVLIVEKEAIFQRLLDG--NIKDKLNSC-IVI--------TGKGYPDMSTRLMIRFLWD--------ALKLPTFVLTDADPYGLEIFCVYKYGSKEMSFEA------ENLCFPLIKWLGVLPSEFNKYT-------------NDKIP---------------------------------------------------------------ISKTIFH----T
B7QAT2/46-264              SKGLFSGDVRFTDGSGNFVDGSFKPT--LVPTDVGGMRNIQ-SSATFILVIEKDATFQKLLND--GFLKSAGPC-ILI--------TGKGYPDVNTRELLRRLHV--------EVDIPVYALVDADPYGIEILCVYAYGSLAMANET------DSMAVPRIRWLGVHPSDVVTFE-------------LKDCPPLSYGDKSKLRNLLARPYV----DSKPAWKEQMVLLDGLQRKAEIQGLC--SVDPTFLSDVYIPSKIKFSG--WI
A7E8A1/59-281              ----------IAYTLGLKRDAMNVSQ--LVPW-VREIEEIDLSQVKWILVIEKEVVHFNL-----QVATSLTQY-RLPFAHWKKSDTAKGYPDIQSRQFLHYLAEN-------HPLIPIYALVDFDPDGIGIMSTYKYGSVALAHEN------EDLSVPSIRWLGLKSTDMMHGV-----------KEDEGLLKLTKRDRRIAVGMLQRD-VCQDGGVEKEWRRQLQIMLMLNTKAEIQVIGNGDLNTGNMS-INKYIKEKMHALSFA
Q0TYH8/84-298              AKGLVAGRFGIIRENGHRIDGMKDREGILVPK-IGENDTMDLASIHWVLVIEKEA---------------------------------KGYPDVASRLFLRRVADQ-------APKIPMFALVDLDPDGMAIMSTYKYGSYRLAHEDTTRKETSGLSLPSIQWIGVRRHHICRTPVDEGGTDASVMPELQGLMKLTARDRTKAACMLEWD-LCAEGGPEEDWRHELQAMLMLNTKAEMQILD--ELPGGLVSWLNCVLG---------
Q86C20/124-342             AKGLLLGNCTMVTQVGTVTASSLVAV-PISPH-FFYLQQIH-TDAQFVLVIEKDTVFEHLIDSYEAIKDRLGQSFMVI--------TGKGYPDAATRALVSFLD---------SCRIPIFGLADGDAHGMNILCTYAYGSASATRKSVV---PNHYIAPSLVPIGVFNSHIQRSS-----------KAIKGSRHCDPADLKLYDILITR--LTALG--RLEWANEVQNLAALGMQYELETIL--GQEGGLVSYVVETVV---------
V6TCN3/127-345             AKGLLLGNCTMVTQVGTVTASSLVAV-PISPH-FFYLQQIH-TDAQFVLVIEKDTVFEHLIDSYEAIKDRLGQSFMVI--------TGKGYPDAATRALVSFLD---------SCRIPIFGLADGDAHGMNILCTYAYGSASATRKSVV---PNHYIAPSLVPIGVFSSHIQRSS-----------KAIKGSRHCDPADLKLYDILITR--LTALG--RLEWANEVQNLAALGMQYELETIL--GQEGGLVSYVVETVV---------
#=GC scorecons             3444336233443337333444233301549305234336415454569789975452363221023232443303450000000065999994569355546210000000032359474959396496495569599924354640000005353494634696336552433000000000002234433233236332222442510413132132463244424326324364434100322454342422344110000001
#=GC scorecons_70          ______*________*______________*________*_______*******_____*__________________________*_*****__**_____*______________*_*_*_*_**_*__*__**_***_____*____________*____***________________________________*______________________*_________*____*_______________________________
#=GC scorecons_80          ______________________________*_________________*_***___________________________________*****___*____________________*_*_*_*_*__*__*___*_***__________________*_____*_______________________________________________________________________________________________________
#=GC scorecons_90          ______________________________*_________________*__**___________________________________*****___*____________________*___*_*_*__*__*___*_***__________________*_____*_______________________________________________________________________________________________________
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