The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Pyridoxal kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 25 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyridoxal kinase activity GO:0008478
Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
8 P39988 (/ISA) P39988 (/ISA) P39988 (/ISA) P39988 (/ISA) P39988 (/ISA) P39988 (/ISA) P39988 (/ISA) P39988 (/ISA)
Pyridoxal kinase activity GO:0008478
Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
6 O00764 (/IDA) O00764 (/IDA) O35331 (/IDA) Q55EK9 (/IDA) Q8W1X2 (/IDA) Q8W1X2 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 O00764 (/IDA) O00764 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 O00764 (/IDA) O00764 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 O00764 (/IDA) O00764 (/IDA)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2 O00764 (/IDA) O00764 (/IDA)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
2 O00764 (/IDA) O00764 (/IDA)
Sodium ion binding GO:0031402
Interacting selectively and non-covalently with sodium ions (Na+).
2 O00764 (/IDA) O00764 (/IDA)
Lithium ion binding GO:0031403
Interacting selectively and non-covalently with lithium ions (Li+).
2 O00764 (/IDA) O00764 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 O00764 (/IDA) O00764 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q8K183 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q8K183 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 O35331 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 Q8K183 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q8K183 (/ISO)
Pyridoxal kinase activity GO:0008478
Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
1 Q55EK9 (/IGI)
Pyridoxal kinase activity GO:0008478
Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
1 Q8K183 (/ISO)
Pyridoxal kinase activity GO:0008478
Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
1 Q7KUC2 (/ISS)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
1 Q8K183 (/ISO)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
1 Q8K183 (/ISO)
Sodium ion binding GO:0031402
Interacting selectively and non-covalently with sodium ions (Na+).
1 Q8K183 (/ISO)
Lithium ion binding GO:0031403
Interacting selectively and non-covalently with lithium ions (Li+).
1 Q8K183 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q8K183 (/ISO)
Pyridoxal binding GO:0070280
Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.
1 O35331 (/IDA)
Pyridoxal binding GO:0070280
Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.
1 Q8K183 (/ISO)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular bud site selection GO:0000282
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
8 P39988 (/HMP) P39988 (/HMP) P39988 (/HMP) P39988 (/HMP) P39988 (/HMP) P39988 (/HMP) P39988 (/HMP) P39988 (/HMP)
Pyridoxal phosphate biosynthetic process GO:0042823
The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
8 P39988 (/IGI) P39988 (/IGI) P39988 (/IGI) P39988 (/IGI) P39988 (/IGI) P39988 (/IGI) P39988 (/IGI) P39988 (/IGI)
Pyridoxal phosphate biosynthetic process GO:0042823
The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
8 P39988 (/IMP) P39988 (/IMP) P39988 (/IMP) P39988 (/IMP) P39988 (/IMP) P39988 (/IMP) P39988 (/IMP) P39988 (/IMP)
Vitamin B6 metabolic process GO:0042816
The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
3 O00764 (/IC) O00764 (/IC) Q55EK9 (/IC)
Pyridoxal phosphate biosynthetic process GO:0042823
The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
3 O00764 (/IDA) O00764 (/IDA) O35331 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
2 O00764 (/IDA) O00764 (/IDA)
Pyridoxine biosynthetic process GO:0008615
The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
2 Q8W1X2 (/TAS) Q8W1X2 (/TAS)
Pyridoxal 5'-phosphate salvage GO:0009443
Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.
2 Q8W1X2 (/IDA) Q8W1X2 (/IDA)
Trichoblast differentiation GO:0010054
The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.
2 Q8W1X2 (/IMP) Q8W1X2 (/IMP)
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q8W1X2 (/IMP) Q8W1X2 (/IMP)
Vitamin B6 metabolic process GO:0042816
The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
2 O00764 (/TAS) O00764 (/TAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
2 O00764 (/TAS) O00764 (/TAS)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q8K183 (/ISO)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 O35331 (/IEP)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
1 O35331 (/IEP)
Response to amine GO:0014075
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
1 O35331 (/IEP)
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
1 O35331 (/IEP)
Asexual reproduction GO:0019954
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
1 Q55EK9 (/IMP)
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 Q55EK9 (/IMP)
Response to food GO:0032094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
1 O35331 (/IEP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 O35331 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 O35331 (/IEP)
Pyridoxal phosphate biosynthetic process GO:0042823
The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
1 Q8K183 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 O35331 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q8K183 (/ISO)
Cellular response to monosaccharide stimulus GO:0071326
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
1 Q7KUC2 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 F2Z2Y4 (/IDA) O00764 (/IDA) O00764 (/IDA) V9HWC3 (/IDA) V9HWC3 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 O00764 (/TAS) O00764 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O00764 (/HDA) O00764 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O00764 (/HDA) O00764 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q8W1X2 (/IDA) Q8W1X2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O00764 (/TAS) O00764 (/TAS)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
2 O00764 (/TAS) O00764 (/TAS)
Specific granule lumen GO:0035580
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2 O00764 (/TAS) O00764 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O00764 (/HDA) O00764 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8K183 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q7KUC2 (/ISS)
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