The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cobalt-precorrin-4 Transmethylase; Domain 1
".
FunFam 4: Putative diphthine synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
17 |
Q75JG8 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
Q8IJV5 (/ISS)
(7 more) |
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
10 | O58456 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) |
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
9 | P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) |
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
3 | Q9H2P9 (/EXP) Q9H2P9 (/EXP) Q9H2P9 (/EXP) |
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
3 | Q9H2P9 (/NAS) Q9H2P9 (/NAS) Q9H2P9 (/NAS) |
|
Diphthine synthase activity GO:0004164
Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
|
2 | O74898 (/ISO) Q9CWQ0 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
10 | O58456 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) P32469 (/IDA) |
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
9 | P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) P32469 (/IMP) |
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
3 | Q9H2P9 (/NAS) Q9H2P9 (/NAS) Q9H2P9 (/NAS) |
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
3 | Q9H2P9 (/TAS) Q9H2P9 (/TAS) Q9H2P9 (/TAS) |
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
2 | Q75JG8 (/ISS) Q8IN02 (/ISS) |
|
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine GO:0017183
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
|
1 | O74898 (/ISO) |
|
S-adenosylmethionine catabolic process GO:0050843
The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
|
1 | O58456 (/IDA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) P32469 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
4 | Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
4 | Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) Q583F0 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q9H2P9 (/TAS) Q9H2P9 (/TAS) Q9H2P9 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O74898 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4Q6A1 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8IN02 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74898 (/HDA) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
1 | Q4Q6A1 (/ISO) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
1 | Q4Q6A1 (/ISO) |
