# STOCKHOLM 1.0 #=GF ID 3.30.870.10/FF/000039 #=GF DE Probable tyrosyl-DNA phosphodiesterase #=GF AC 3.30.870.10/FF/000039 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 80.611 #=GS Q9VQM4/339-579 AC Q9VQM4 #=GS Q9VQM4/339-579 OS Drosophila melanogaster #=GS Q9VQM4/339-579 DE Probable tyrosyl-DNA phosphodiesterase #=GS Q9VQM4/339-579 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VQM4/339-579 DR GO; GO:0005634; GO:0006281; GO:0007417; GO:0017005; GO:0045197; #=GS E9FSK3/349-580 AC E9FSK3 #=GS E9FSK3/349-580 OS Daphnia pulex #=GS E9FSK3/349-580 DE Uncharacterized protein #=GS E9FSK3/349-580 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS D7GXI0/303-543 AC D7GXI0 #=GS D7GXI0/303-543 OS Tribolium castaneum #=GS D7GXI0/303-543 DE Putative tyrosyl-DNA phosphodiesterase-like Protein #=GS D7GXI0/303-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q5TSF5/346-583 AC Q5TSF5 #=GS Q5TSF5/346-583 OS Anopheles gambiae #=GS Q5TSF5/346-583 DE AGAP010577-PA #=GS Q5TSF5/346-583 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS H3GC32/227-496 AC H3GC32 #=GS H3GC32/227-496 OS Phytophthora ramorum #=GS H3GC32/227-496 DE Uncharacterized protein #=GS H3GC32/227-496 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS B7PRG3/362-618 AC B7PRG3 #=GS B7PRG3/362-618 OS Ixodes scapularis #=GS B7PRG3/362-618 DE Tyrosyl-DNA phosphodiesterase, putative #=GS B7PRG3/362-618 DR ORG; Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes; Ixodes scapularis; #=GS A0A084WI56/390-626 AC A0A084WI56 #=GS A0A084WI56/390-626 OS Anopheles sinensis #=GS A0A084WI56/390-626 DE AGAP010577-PA-like protein #=GS A0A084WI56/390-626 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS A0A1Y9GLD9/397-634 AC A0A1Y9GLD9 #=GS A0A1Y9GLD9/397-634 OS Anopheles arabiensis #=GS A0A1Y9GLD9/397-634 DE Uncharacterized protein #=GS A0A1Y9GLD9/397-634 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles arabiensis; #=GS A0A182S510/392-628 AC A0A182S510 #=GS A0A182S510/392-628 OS Anopheles funestus #=GS A0A182S510/392-628 DE Uncharacterized protein #=GS A0A182S510/392-628 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; funestus group; funestus subgroup; Anopheles funestus; #=GS A0A182ITF6/404-640 AC A0A182ITF6 #=GS A0A182ITF6/404-640 OS Anopheles atroparvus #=GS A0A182ITF6/404-640 DE Uncharacterized protein #=GS A0A182ITF6/404-640 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Angusticorn; Anopheles; maculipennis group; Anopheles atroparvus; #=GS B4Q941/339-579 AC B4Q941 #=GS B4Q941/339-579 OS Drosophila simulans #=GS B4Q941/339-579 DE GD23212 #=GS B4Q941/339-579 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B3N203/335-575 AC B3N203 #=GS B3N203/335-575 OS Drosophila ananassae #=GS B3N203/335-575 DE Uncharacterized protein #=GS B3N203/335-575 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS B4GSG0/270-510 AC B4GSG0 #=GS B4GSG0/270-510 OS Drosophila persimilis #=GS B4GSG0/270-510 DE GL26495 #=GS B4GSG0/270-510 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; #=GS A0A3B0KF10/336-576 AC A0A3B0KF10 #=GS A0A3B0KF10/336-576 OS Drosophila guanche #=GS A0A3B0KF10/336-576 DE Blast:Probable tyrosyl-DNA phosphodiesterase #=GS A0A3B0KF10/336-576 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS A0A1W4V7I2/339-579 AC A0A1W4V7I2 #=GS A0A1W4V7I2/339-579 OS Drosophila ficusphila #=GS A0A1W4V7I2/339-579 DE probable tyrosyl-DNA phosphodiesterase #=GS A0A1W4V7I2/339-579 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS Q29L30/335-575 AC Q29L30 #=GS Q29L30/335-575 OS Drosophila pseudoobscura pseudoobscura #=GS Q29L30/335-575 DE Uncharacterized protein #=GS Q29L30/335-575 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS B3NAR4/339-579 AC B3NAR4 #=GS B3NAR4/339-579 OS Drosophila erecta #=GS B3NAR4/339-579 DE Uncharacterized protein #=GS B3NAR4/339-579 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4NXE5/339-580 AC B4NXE5 #=GS B4NXE5/339-580 OS Drosophila yakuba #=GS B4NXE5/339-580 DE Uncharacterized protein #=GS B4NXE5/339-580 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GF SQ 18 Q9VQM4/339-579 VFFLGSVPGGH---REGSVRGHPWGHARLASLLAKHAAP---IDDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLKKDS-TPVGKLRQMPPFKMIYPSYGNVAGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSD-RFRSRAMPHIKSYTRFNLEDQ---SVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQ-------------- E9FSK3/349-580 VCFIPSSPGSHAIQSEANEKVPKWGHLHLSWLLQQHASS---EADD-S---------IIMQCSSIGSLGPSPSSWLAGELGVSMGASS---GVTKLGQKNVQVVYPCFQDVKSSIHGLLGGGCLPYSHQGHNKQTWFTGFLHKWRSDS-RLRTTAMPHIKSYARVSSDMS---RASFFVLTSANVSKAAWGMRINK---DTKLMIQSFEAGVLFLPKFLFGEM------TFKLGKQ---------------------LRLPYDLPLTKYGA-GDEPWFIDNLR-------------- D7GXI0/303-543 VFLVTSVPGKH----YPGTQGSHVHH--VGDLLSRHCSL---PAKTGPDSEGPLSWGIIAQASSIGSMGKSPAEWLRSTLLRSLSGHK-QTQLVSNSNATLSIIFPSVDNVMNGYFGAESGGCLPYSKQTNEKQRWLQSYLHQWKADK-LGRSRAMPHIKTYCRVSPCLS---KLAWFFITSANLSKSAWGGNLQK---DKGAYVRSYEAGVMFLPKFFDEE-------YFEIETT-LSGKNK------------KLFPFMYDLPLTEYKS-SDYPWC------------------N Q5TSF5/346-583 VFLVASVPGGH----TNTAKGPLWGHPRLGYLLSQHAAP---IDDSCP---------LVAQSSSIGSLGPSPESWVLGEIMASFRKDS-APVG-IRRLPGFRMIYPSFSNVRQSHDGMMGGGCLPYVRSTHVKQEWLKDYLQQWCSRA-RHRNKAMPHIKTYCRWS--HR---GLYWFLLTSANLSKAAWGVYNKTGRFEKPLRINSYEAGVLFLPKLLLDEN------FFPMEAN----KKH------------PQFPMPYDVPTIPYAP-EDTPFFMDYLTQ------------H H3GC32/227-496 VALIPSVPGVH-----KGKDMERYGHLRVRKLLKTFNVP---QTDN-P---------LICQFSSLGSL---DEKWLFGEFAESFLPGKKNISASSMPVQALHIIWPSVEDVRNSLEGWNSGRSIPCPLK--NMKPFLHKYLRKWTPPSVLHRQNAMPHIKSYARFDPSDEAAGALDWAIVTSSNLSKAAWGTLQKK---KTQFMVRSYELGVMFLPPLLAHQNGGTSPHLVTIGSKAAAGHSGVEDFESSEKQPKELLPLPYGFPLTTYNPKQDEPWVWDLVRD-SPDIFGNAYMPH B7PRG3/362-618 VFLVGSVPGRH-----TGARKSSFGHLKLRKLLSLHGPPKELVSSYWP---------AIAQFSSIGSLGTGPDNWLRAEFLTSLAAVKGGPPLTPSSTVPVKLVFPSVDDVRCSLEGYPAGASIPYSISTANKQRWLDAYFFRWRSGR-FGRTHASPHVKSYARLSPSGK---QTAWLLVTSANLSKAAWGAFEKS---GSQLMIRSYELGVLFFPGQFGDAR------TFTVGGDSMAGKGC------------LPLFVPFDVPLTPYGQ-DDVPWTWDSQHREAPDRFGNMWCPP A0A084WI56/390-626 VCLVASVPGGH----VNTPKGPLWGHPRLGHLLAQHAAP---IDDTCP---------LVAQSSSIGSLGPSPESWVLAEIMASFRKDS-APVG-IRRQPGFRMIYPSYSNVRQSHDGLLGGGCLPYVRNTHVKQEWLKDYLHQWCSRT-RHRNKAMPHIKTYCRWS--HR---GLYWFLLTSANLSKSAWGVYNKTGRFEKPLRINSYEIGVLFLPKLMLDEN------FFPMDGN----KKH------------PAFPMPYDVPIVPYAP-EDTPFLMDYLTQ------------- A0A1Y9GLD9/397-634 VFLVASVPGGH----TNTAKGPLWGHPRLGYLLSQHAAP---IDDSCP---------LVAQSSSIGSLGPSPESWVLGEIMASFRKDS-APVG-IRRLPGFRMIYPSFSNVRQSHDGMMGGGCLPYVRSTHVKQEWLKDYLQQWCSRA-RHRNKAMPHIKTYCRWS--HR---GLYWFLLTSANLSKAAWGVYNKTGRFEKPLRINSYEAGVLFLPKLLLDEN------FFPMEAN----KKH------------PQFPMPYDVPTIPYAP-EDTPFFMDYLTQ------------H A0A182S510/392-628 VFLIASVPGGH----TNTPKGPLWGHPRLGHVLSQHAAP---IDDACP---------LVAQSSSIGSLGPSPESWVLGEIMASFRKDS-APVG-IRRLPGFRMIYPSYSNVRQSHDGLLGGGCLPYVRNTHVKQEWLKGYLHQWCSRT-RHRNKAMPHIKTYCRWS--HR---GLYWFLLTSANLSKSAWGVYNKTGRFEKPLRINSYEVGVLFLPKMLLDEN------FFPMESN----KKH------------PPFPMPYDIPIIPYAP-EDTPFFMDYLQQ------------- A0A182ITF6/404-640 VCLVASVPGGH----VNTPKGPLWGHPRLGHLLARHAAP---VDDSCP---------LVAQSSSIGSLGPTPESWVLAEIMASFRKDS-APVG-IRRLPGFRMIYPSYSNVRQSHDGLLGGGCLPYVRATNVKQEWLKDYLHQWCSRT-RHRNKAMPHIKTYCRWS--HR---GLYWFLLTSANLSKAAWGVYNKTGRFEKPLRINSYEIGVLFLPKLLLDEN------FFPMEAN----KKH------------PPFPMPYDVPIVPYAP-EDTPFLMDYLTQ------------- B4Q941/339-579 VFFLGSVPGGH---REGSVRGHPWGHARLASLLAKHAAP---IDDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLKKDS-TPVGKLRQMPPFKMIYPSYGNVSGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSD-RYRSRAMPHIKSYTRFNLEDQ---SVYWFVLTSANLSKAAWGCFNKSSNIQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQ-------------- B3N203/335-575 VFFLGSVPGGH---RESTVRGHPWGHARLGALLAKHATP---INDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLKKDS-TPLGKLRQMPTFKMIYPSFGNVSGSHDGMLGGGCLPYGKNTNDKQPWLKDHLHQWKSND-RYRSRAMPHIKTYTRYNLEDQ---SVYWFVLTSANLSKAAWGCFNKNSNVQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQ-------------- B4GSG0/270-510 VFFVGSVPGGH---REGSVRGHPWGHARLGSLLAKHATP---IDDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLRKDS-SPGGKLRQMPPFKMIYPSFNNVSGSHDGMIGGGCLPYGKNTNDKQPWLKAHLQQWKSSD-RHRSRAMPHIKTYSRYNLTDQ---SIYWFVLTSANLSKAAWGSFNKNTNLQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----REGV-----------PAFPLPYDVPLTPYLP-DDKPFLMDYLQ-------------- A0A3B0KF10/336-576 VFFVGSVPGGH---REGSVRGHPWGHARLGSLLAKHAAP---IEDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLRKDS-SPGGKLRQMPPFKMIYPSFNNVSGSHDGMIGGGCLPYGKNTNDKQPWLKGHLQQWKATD-RHRSRAMPHIKSYTRYNLTDQ---SVYWFVLTSANLSKAAWGSFNKNSNLQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYLP-DDKPFLMDYLQ-------------- A0A1W4V7I2/339-579 VFFLGSVPGGH---RESAVRGHPWGHARLGALLSKHATP---IDDRIP---------VVCQSSSIGSLGPNVQSWIQQDFVNCLKKDS-TPVGKLRQMPAFKMIYPSFGNVSGSHDGMLGGGCLPYGKNTNDKQPWLKEYLQQWKSSD-RYRSRAMPHIKSYTRYNLEDQ---SVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEVGVLFLPRFLTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQ-------------- Q29L30/335-575 VFFVGSVPGGH---REGSVRGHPWGHARLGSLLAKHATP---IDDRIP---------VVCQSSSIGSLGANVQAWIQQDFVNSLRKDS-SPGGKLRQMPPFKMIYPSFNNVSGSHDGMIGGGCLPYGKNTNDKQPWLKAHLQQWKSSD-RHRSRAMPHIKTYTRYNLTDQ---SVYWFVLTSANLSKAAWGSFNKNTNLQPCLRIANYEAGVLFLPRFVTGED------TFPLGNN----REGV-----------PAFPLPYDVPLTPYLP-DDKPFLMDYLQ-------------- B3NAR4/339-579 VFFLGSVPGGH---RESSVRGHPWGHARLGSLLSKHAAP---IDDRIP---------VVCQSSSIGSLGVSVQAWIQQDFVNSLKKDS-TPVGKLRQMPPFKMIYPSFGNVSGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSD-RYRSRAMPHIKSYTRFNLEDQ---SVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEVGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQ-------------- B4NXE5/339-580 VFFLGSVPGGH---RESSVRGHPWGHARLGSLLSKHATP---IDDRIP---------VICQSSSIGSLGANVQAWIQQDFVNSLKKDS-TPAGKLRQMPPFKMIYPSFGNVSGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSD-RYRSRAMPHIKSYTRFNLEEQ---SVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEVGVLFLPRFVTGED------TFPLGNN----RDGV-----------PAFPLPYDVPLTPYAP-DDKPFLMDYLQG------------- #=GC scorecons 956649799590001234355435793675389447647000446328000000000574959989987344449534654486455603534234445455676985469448559446967798444644784785478569463305494597998969493521340004547656997989979993447422244364746895997989555356400000047556450000533100000000000436667876966594605939544745410000000000000 #=GC scorecons_70 *_*__****_*_____________**__*__**__*__*_____*__*__________*_*_*******_____*___*___*___________________*****__**__*__*__*******___*__**_**__**_**_*_____*__******_*_*____________**_************___*_______*_*_***_******_____*________*__________________________**_***_***_*_*__*_*___*_________________ #=GC scorecons_80 *____****_*_____________**__*__**__*___________*____________*_*******_____*_______*____________________*_**___*__*__*___*_****______**_**__**__*_______*__******_*_*____________*___*******_***___*_________*__**_******______________*_____________________________***_*___*____*_*___*_________________ #=GC scorecons_90 *____*_**_*______________*_____**______________*____________*_**_***______*_______*______________________**___*_____*___*___*___________*___*__*_______*__*_****_*_*________________**_****_***________________**_**_***_____________________________________________*__*___*____*_*_____________________ //