# STOCKHOLM 1.0
#=GF ID 3.30.70.660/FF/000015
#=GF DE tRNA pseudouridine synthase
#=GF AC 3.30.70.660/FF/000015
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 84.193
#=GS P53167/107-120_173-368      AC P53167
#=GS P53167/107-120_173-368      OS Saccharomyces cerevisiae S288C
#=GS P53167/107-120_173-368      DE tRNA pseudouridine(27/28) synthase
#=GS P53167/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P53167/107-120_173-368      DR GO; GO:0005739; GO:0009982; GO:0031119; GO:1990481; 
#=GS P53167/107-120_173-368      DR EC; 5.4.99.44; 
#=GS O94295/153-166_256-448      AC O94295
#=GS O94295/153-166_256-448      OS Schizosaccharomyces pombe 972h-
#=GS O94295/153-166_256-448      DE tRNA pseudouridine synthase 2
#=GS O94295/153-166_256-448      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS O94295/153-166_256-448      DR GO; GO:0005634; GO:0009982; GO:0031119; 
#=GS E3L261/159-172_225-448      AC E3L261
#=GS E3L261/159-172_225-448      OS Puccinia graminis f. sp. tritici CRL 75-36-700-3
#=GS E3L261/159-172_225-448      DE Uncharacterized protein
#=GS E3L261/159-172_225-448      DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia graminis; 
#=GS A2FDS7/153-351              AC A2FDS7
#=GS A2FDS7/153-351              OS Trichomonas vaginalis
#=GS A2FDS7/153-351              DE tRNA pseudouridine synthase
#=GS A2FDS7/153-351              DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; 
#=GS H0GG93/107-120_173-368      AC H0GG93
#=GS H0GG93/107-120_173-368      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GG93/107-120_173-368      DE tRNA pseudouridine synthase
#=GS H0GG93/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS A0A0L8VQI2/107-120_173-368  AC A0A0L8VQI2
#=GS A0A0L8VQI2/107-120_173-368  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VQI2/107-120_173-368  DE tRNA pseudouridine synthase
#=GS A0A0L8VQI2/107-120_173-368  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS N1P5H6/107-120_173-368      AC N1P5H6
#=GS N1P5H6/107-120_173-368      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1P5H6/107-120_173-368      DE tRNA pseudouridine synthase
#=GS N1P5H6/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1P5H6/107-120_173-368      DR EC; 5.4.99.44; 
#=GS G2WE33/107-120_173-368      AC G2WE33
#=GS G2WE33/107-120_173-368      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2WE33/107-120_173-368      DE tRNA pseudouridine synthase
#=GS G2WE33/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C7GW47/107-120_173-368      AC C7GW47
#=GS C7GW47/107-120_173-368      OS Saccharomyces cerevisiae JAY291
#=GS C7GW47/107-120_173-368      DE tRNA pseudouridine synthase
#=GS C7GW47/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A6ZUB3/107-120_173-368      AC A6ZUB3
#=GS A6ZUB3/107-120_173-368      OS Saccharomyces cerevisiae YJM789
#=GS A6ZUB3/107-120_173-368      DE tRNA pseudouridine synthase
#=GS A6ZUB3/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LHD2/107-120_173-368      AC B3LHD2
#=GS B3LHD2/107-120_173-368      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LHD2/107-120_173-368      DE tRNA pseudouridine synthase
#=GS B3LHD2/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C8Z8I3/107-120_173-368      AC C8Z8I3
#=GS C8Z8I3/107-120_173-368      OS Saccharomyces cerevisiae EC1118
#=GS C8Z8I3/107-120_173-368      DE tRNA pseudouridine synthase
#=GS C8Z8I3/107-120_173-368      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A2DE30/144-339              AC A2DE30
#=GS A2DE30/144-339              OS Trichomonas vaginalis
#=GS A2DE30/144-339              DE tRNA pseudouridine synthase
#=GS A2DE30/144-339              DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; 
#=GS A2E6F9/148-341              AC A2E6F9
#=GS A2E6F9/148-341              OS Trichomonas vaginalis
#=GS A2E6F9/148-341              DE tRNA pseudouridine synthase
#=GS A2E6F9/148-341              DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; 
#=GF SQ 14
P53167/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
O94295/153-166_256-448              ESRTYEYLIPSFALLKQ----AEYYCYM-----NYRIKEDRLKVLQQLLKKYEGRHNFHNFTVT-DDSTSPSNYRFIESVTCGTPFVYEN-------------------WEWIPVTIKGNSFMLNQIRKMMAHVLMIIRSCAPTGLIDKAFDPNITMNISKSPGHVLLLKDIKFSSYNDSVTDGL----------------------------EKIQFDCFEEDILSLKIKTIYPDIIKLEQKEKLFFSFLSYIDQHTGHQFDY
E3L261/159-172_225-448              DSRVYEYSLPTWLFFKS---------IQAERRGSYRISQMMIARIKSVLDQFRGTHNFHNLTVG-KAFTERNAVRIMKDFTVSEPFLVGGSDPTNPKDDDDHQPLENPPTEWISITFHGQSFMLHQIRKMIGLLVLVCRTRTPVSIIKQLYGPR-KVSIPKAPGIGLILRKLNFHGYNKKIQHINEQTLQRRNKKRKGARNGGDQEDDQLMIWDSIECDRFEALFERFKLETLFNRI------------FLNQTSQ---ISNEP
A2FDS7/153-351                      SSRRYHYLLPVNTFSSENIDHLNYL-------------------RAKICPIFVGRHQYANYTRHITDELLHTSIKTISEFTFTDPFDVNG-------------------TKYVLFTISGNSFMLNQIRKMIAAVLAVSHHLMTEDDLKDTLTET-RWLLPRLIGTGLFLDQVFFEQNQIIRQHKDKPIP----------------------KKKDIHFSFVSEEIEVWKRNILFNHIDQIVKEKDPFKEWVNNILL----QFPP
H0GG93/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
A0A0L8VQI2/107-120_173-368          DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
N1P5H6/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
G2WE33/107-120_173-368              DSRWYQYLIPEFILSESDPLVQEYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITIERMCRFRERQIYTAIAHEETQRHVFSHFVRQMNR----LATP
C7GW47/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
A6ZUB3/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
B3LHD2/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
C8Z8I3/107-120_173-368              DSRWYQYLIPEFILSESDPLVQDYVGLLSGTLSGYCLPPSKLDAFEAAMQEYVGTHNFHNFTTG-KLWGDPSAQRHIKKVVVSQ----AS-------------------PGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLL--------------------------YCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNR----LATP
A2DE30/144-339                      ESRNYNFLLPTNAFSSNSIEHLNYL-------------------RTSILPLFIGWLNYHNFTSN-KSASNPSSMRKIDVFTFTDPFEVEG-------------------VEFVLFTIHGESFMLNQIRKMIATVISASHNYIGAEEVKRCLSEE-GWSIKMCPGDGLMLDHVDYIKCN-KPSKKN-PIT----------------------FENDLQFTEFQPEIQRWKKEVLFPHIAEIIKKKDLYHKWVIEYLP----KYPW
A2E6F9/148-341                      THRKYNYLLPLHVFSSTDPDHLDYL-------------------RQKICPLFIGQHNFHNYTNG-TPKTYKGAQRFITDFTFGDVFTING-------------------EEYVLFYIRGISFMLNQIRKMISMVTAASFNQVTPEEVSRSLTEE-TCRIQLLPGDGLFLDQIEYEEYMSKLKHPN--------------------------PNNDIEFRAWRPVIEEWKQKVLFPHIAQTIKKTDVFRSWQKNCLL----QFPV
#=GC scorecons                      579294876934466443322346312211111232212223223444443749477779694505324355538374355554120145000000000000000000035573547594999969997966455454544454446543644414337544763795954437446636445340000000000000000000000000022534435333535355735365449442334334623554443400003344
#=GC scorecons_70                   _**_*_****___*_________*___________________________*_*_*******____________*_*___________________________________*___*_*_****_*******______________*___________*___*__**_*____*__*___________________________________________________*___*___*___________________________
#=GC scorecons_80                   _**_*_**_*_________________________________________*_*_*****_*____________*_*___________________________________*___*_*_****_***_*____________________________*___*__**_*____*______________________________________________________________*___________________________
#=GC scorecons_90                   __*_*_*__*___________________________________________*_____*_*____________*___________________________________________*_****_***_*____________________________________*_*___________________________________________________________________*___________________________
//