The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 397: RNA binding protein Nrd1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
6 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) Q9UTE3 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P53617 (/IPI) P53617 (/IPI) P53617 (/IPI) P53617 (/IPI) P53617 (/IPI) Q9UTE3 (/IPI)
Transcription regulatory region RNA binding GO:0001068
Interacting selectively and non-covalently with a RNA region within the transcript that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon.
5 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
5 P53617 (/HDA) P53617 (/HDA) P53617 (/HDA) P53617 (/HDA) P53617 (/HDA)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
5 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9UTE3 (/IPI)
RNA polymerase II C-terminal domain binding GO:0099122
Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
1 Q9UTE3 (/IPI)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
6 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) Q9UTE3 (/IMP)
SnoRNA 3'-end processing GO:0031126
Any process involved in forming the mature 3' end of a snoRNA molecule.
6 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) Q9UTE3 (/IMP)
Termination of RNA polymerase II transcription, exosome-dependent GO:0030847
The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
5 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA)
SnRNA 3'-end processing GO:0034472
Any process involved in forming the mature 3' end of an snRNA molecule.
5 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP)
TRNA 3'-end processing GO:0042780
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
5 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP)
Nuclear mRNA surveillance GO:0071028
The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.
5 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP)
CUT catabolic process GO:0071034
The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).
5 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP)
Antisense RNA transcript catabolic process GO:0071041
The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.
5 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA)
Antisense RNA transcript catabolic process GO:0071041
The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.
5 P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP) P53617 (/IMP)
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
1 Q9UTE3 (/IMP)
Termination of RNA polymerase II transcription, poly(A)-coupled GO:0030846
The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.
1 Q9UTE3 (/IC)
Termination of RNA polymerase II transcription, poly(A)-coupled GO:0030846
The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.
1 Q9UTE3 (/IMP)
Termination of RNA polymerase II transcription, exosome-dependent GO:0030847
The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
1 Q9UTE3 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P53617 (/IC) P53617 (/IC) P53617 (/IC) P53617 (/IC) P53617 (/IC)
Nrd1 complex GO:0035649
A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.
5 P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA) P53617 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UTE3 (/EXP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UTE3 (/HDA)
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