# STOCKHOLM 1.0 #=GF ID 3.30.590.50/FF/000006 #=GF DE Glutamate--cysteine ligase #=GF AC 3.30.590.50/FF/000006 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 79.462 #=GS P32477/428-523 AC P32477 #=GS P32477/428-523 OS Saccharomyces cerevisiae S288C #=GS P32477/428-523 DE Glutamate--cysteine ligase #=GS P32477/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS P32477/428-523 DR GO; GO:0004357; GO:0005622; GO:0006750; GO:0042542; GO:0046686; #=GS P32477/428-523 DR EC; 6.3.2.2; #=GS Q6FLG3/426-521 AC Q6FLG3 #=GS Q6FLG3/426-521 OS [Candida] glabrata CBS 138 #=GS Q6FLG3/426-521 DE Uncharacterized protein #=GS Q6FLG3/426-521 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces; [Candida] glabrata; #=GS Q6FLG3/426-521 DR GO; GO:0006750; GO:0071585; #=GS A8BN69/340-447 AC A8BN69 #=GS A8BN69/340-447 OS Giardia lamblia ATCC 50803 #=GS A8BN69/340-447 DE Glutamate-cysteine ligase #=GS A8BN69/340-447 DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; #=GS H2M1L3/355-439 AC H2M1L3 #=GS H2M1L3/355-439 OS Oryzias latipes #=GS H2M1L3/355-439 DE Uncharacterized protein #=GS H2M1L3/355-439 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS Q754I8/416-508 AC Q754I8 #=GS Q754I8/416-508 OS Eremothecium gossypii ATCC 10895 #=GS Q754I8/416-508 DE AFR086Cp #=GS Q754I8/416-508 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium; Eremothecium gossypii; #=GS R9XI17/416-508 AC R9XI17 #=GS R9XI17/416-508 OS Saccharomycetaceae sp. 'Ashbya aceri' #=GS R9XI17/416-508 DE AaceriAFR086Cp #=GS R9XI17/416-508 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomycetaceae sp. 'Ashbya aceri'; #=GS A0A0L8VMQ0/428-523 AC A0A0L8VMQ0 #=GS A0A0L8VMQ0/428-523 OS Saccharomyces sp. 'boulardii' #=GS A0A0L8VMQ0/428-523 DE GSH1p Gamma glutamylcysteine synthetase #=GS A0A0L8VMQ0/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; #=GS A0A0L8VMQ0/428-523 DR EC; 6.3.2.2; #=GS H0GI98/428-523 AC H0GI98 #=GS H0GI98/428-523 OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 #=GS H0GI98/428-523 DE Gsh1p #=GS H0GI98/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; #=GS A0A0L8RGD6/424-523 AC A0A0L8RGD6 #=GS A0A0L8RGD6/424-523 OS Saccharomyces eubayanus #=GS A0A0L8RGD6/424-523 DE GSH1-like protein #=GS A0A0L8RGD6/424-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces eubayanus; #=GS A0A1S3SYJ9/293-378 AC A0A1S3SYJ9 #=GS A0A1S3SYJ9/293-378 OS Salmo salar #=GS A0A1S3SYJ9/293-378 DE glutamate--cysteine ligase catalytic subunit-like isoform X3 #=GS A0A1S3SYJ9/293-378 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Salmoniformes; Salmonidae; Salmoninae; Salmo; Salmo salar; #=GS A0A3Q2DDA3/353-439 AC A0A3Q2DDA3 #=GS A0A3Q2DDA3/353-439 OS Cyprinodon variegatus #=GS A0A3Q2DDA3/353-439 DE Uncharacterized protein #=GS A0A3Q2DDA3/353-439 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Cyprinodontidae; Cyprinodontinae; Cyprinodontini; Cyprinodon; Cyprinodon variegatus; #=GS A0A146YXR2/485-571 AC A0A146YXR2 #=GS A0A146YXR2/485-571 OS Fundulus heteroclitus #=GS A0A146YXR2/485-571 DE Glutamate--cysteine ligase catalytic subunit #=GS A0A146YXR2/485-571 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Fundulidae; Fundulus; Fundulus heteroclitus; #=GS A0A3B5LX68/389-477 AC A0A3B5LX68 #=GS A0A3B5LX68/389-477 OS Xiphophorus couchianus #=GS A0A3B5LX68/389-477 DE Glutamate-cysteine ligase, catalytic subunit #=GS A0A3B5LX68/389-477 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Poeciliidae; Poeciliinae; Xiphophorus; Xiphophorus couchianus; #=GS C7GR13/428-523 AC C7GR13 #=GS C7GR13/428-523 OS Saccharomyces cerevisiae JAY291 #=GS C7GR13/428-523 DE Gsh1p #=GS C7GR13/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C7GR13/428-523 DR EC; 6.3.2.2; #=GS C8ZB62/428-523 AC C8ZB62 #=GS C8ZB62/428-523 OS Saccharomyces cerevisiae EC1118 #=GS C8ZB62/428-523 DE Gsh1p #=GS C8ZB62/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C8ZB62/428-523 DR EC; 6.3.2.2; #=GS N1P8E6/428-523 AC N1P8E6 #=GS N1P8E6/428-523 OS Saccharomyces cerevisiae CEN.PK113-7D #=GS N1P8E6/428-523 DE Gsh1p #=GS N1P8E6/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS N1P8E6/428-523 DR EC; 6.3.2.2; #=GS B3LQ12/428-523 AC B3LQ12 #=GS B3LQ12/428-523 OS Saccharomyces cerevisiae RM11-1a #=GS B3LQ12/428-523 DE Gamma-glutamylcysteine synthetase #=GS B3LQ12/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS B3LQ12/428-523 DR EC; 6.3.2.2; #=GS V6T8P3/340-447 AC V6T8P3 #=GS V6T8P3/340-447 OS Giardia intestinalis #=GS V6T8P3/340-447 DE Glutamate--cysteine ligase #=GS V6T8P3/340-447 DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; #=GS G2WGR7/428-523 AC G2WGR7 #=GS G2WGR7/428-523 OS Saccharomyces cerevisiae Kyokai no. 7 #=GS G2WGR7/428-523 DE K7_Gsh1p #=GS G2WGR7/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS A6ZPM3/428-523 AC A6ZPM3 #=GS A6ZPM3/428-523 OS Saccharomyces cerevisiae YJM789 #=GS A6ZPM3/428-523 DE Gamma-glutamylcysteine synthetase #=GS A6ZPM3/428-523 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS A0A0W0E5S4/426-521 AC A0A0W0E5S4 #=GS A0A0W0E5S4/426-521 OS [Candida] glabrata #=GS A0A0W0E5S4/426-521 DE Glutamate--cysteine ligase #=GS A0A0W0E5S4/426-521 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces; [Candida] glabrata; #=GS A0A3B3HSU7/393-477 AC A0A3B3HSU7 #=GS A0A3B3HSU7/393-477 OS Oryzias latipes #=GS A0A3B3HSU7/393-477 DE Uncharacterized protein #=GS A0A3B3HSU7/393-477 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS A0A3P9JX21/393-477 AC A0A3P9JX21 #=GS A0A3P9JX21/393-477 OS Oryzias latipes #=GS A0A3P9JX21/393-477 DE Glutamate-cysteine ligase, catalytic subunit #=GS A0A3P9JX21/393-477 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS A0A146MJG1/300-387 AC A0A146MJG1 #=GS A0A146MJG1/300-387 OS Fundulus heteroclitus #=GS A0A146MJG1/300-387 DE Glutamate--cysteine ligase catalytic subunit #=GS A0A146MJG1/300-387 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Fundulidae; Fundulus; Fundulus heteroclitus; #=GS A0A146YYW0/390-477 AC A0A146YYW0 #=GS A0A146YYW0/390-477 OS Fundulus heteroclitus #=GS A0A146YYW0/390-477 DE Glutamate--cysteine ligase catalytic subunit #=GS A0A146YYW0/390-477 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Fundulidae; Fundulus; Fundulus heteroclitus; #=GS A0A146NH77/432-519 AC A0A146NH77 #=GS A0A146NH77/432-519 OS Fundulus heteroclitus #=GS A0A146NH77/432-519 DE Glutamate--cysteine ligase catalytic subunit #=GS A0A146NH77/432-519 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Cyprinodontiformes; Cyprinodontoidei; Fundulidae; Fundulus; Fundulus heteroclitus; #=GF SQ 26 P32477/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR Q6FLG3/426-521 -----------------QDNSTSTNHFENIQSTNWQTLRFKPPTQEATPDNHNVPGWRVEFRPLDIQLLDFENAAFSNMMYMIVDFVLQNTDKINPYVPMSQVWENMIRAHHR A8BN69/340-447 SVISHFPLVVLRDSLVFHDESFDSDCWDQIHSLFWPTCRWKVPPIDSLKGST---GWRTEVRCMEMQFSIAENLAYSVFVFLLSSAIRDMG--LLFYIPQTFILQDMSSAEKR H2M1L3/355-439 --------------------ENESDHFENLQSTNWQTMRFKPP-----PPNSEI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQER Q754I8/416-508 --------------------DSDMGHFENIQSTNWQTVRFKPPTQDATPGNMSVPGWRVEFRPMEVQLNDFENAAFANFVYLLVECMVEFKDDINAYVPMNLVWENMDIAHQR R9XI17/416-508 --------------------DSDMGHFENIQSTNWQTVRFKPPTQDATPGNMSVPGWRVEFRPMEIQLHDFENAAFANFVYLLVECMVEFKEDINAYVPMSLVWENMDIAHQR A0A0L8VMQ0/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR H0GI98/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR A0A0L8RGD6/424-523 -------------ELLHQDNKSSTNHFENIQSTNWQTLRFKPPTQHATPDKKDAPGWRVEFRPFEVQLLDFENAAYSMFIYLIVDSILTFSDDINAYIHMSKVWENMKTAHHR A0A1S3SYJ9/293-378 -------------------DENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENSAYVVFIVLLTRVILSYK--LDFLIPLSKVDENMKAAQER A0A3Q2DDA3/353-439 ------------------DDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR A0A146YXR2/485-571 ------------------DDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR A0A3B5LX68/389-477 ----------------HLDDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR C7GR13/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR C8ZB62/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR N1P8E6/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR B3LQ12/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR V6T8P3/340-447 SVISHFPLVVLRDSLVFHDESFDSDCWDQIHSLFWPTCRWKVPPIDSLKGST---GWRTEVRCMEMQFSIAENLAYSVFVFLLSSAIRDMG--LLFYIPQTFILQDMSFAEKR G2WGR7/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR A6ZPM3/428-523 -----------------QDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHR A0A0W0E5S4/426-521 -----------------QDNSTSTNHFENIQSTNWQTLRFKPPTQEATPDNHNVPGWRVEFRPLDIQLLDFENAAFSNMMYMIVDFVLQNTDKINPYVPMSQVWENMIRAHHR A0A3B3HSU7/393-477 --------------------ENESDHFENLQSTNWQTMRFKPP-----PPNSEI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQER A0A3P9JX21/393-477 --------------------ENESDHFENLQSTNWQTMRFKPP-----PPNSEI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQER A0A146MJG1/300-387 -----------------LDDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR A0A146YYW0/390-477 -----------------LDDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR A0A146NH77/432-519 -----------------LDDENESDHFENLQSTNWQTMRFKPP-----PPNSDI-GWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYK--LDFLIPLSKVDENMKVAQKR #=GC scorecons 00000000000000000253445667787679769795979792222274544329997979758797466996985666486544764541165457657583779549559 #=GC scorecons_70 _______________________*_************_*****_____*______********_****_*******_***_**___*______*___*__*_*_***__*__* #=GC scorecons_80 _________________________*_**_**__***_*_*_*____________*******__*_**___**_**_____*____*__________*____*_***__*__* #=GC scorecons_90 _______________________________*__*_*_*_*_*____________***_*_*__*_*____**_**_____*________________________*__*__* //