# STOCKHOLM 1.0
#=GF ID 3.30.572.10/FF/000009
#=GF DE Thymidylate synthase
#=GF AC 3.30.572.10/FF/000009
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 61.124
#=GS 1tisA00/1-286     AC P00471
#=GS 1tisA00/1-286     OS Escherichia virus T4
#=GS 1tisA00/1-286     DE Thymidylate synthase
#=GS 1tisA00/1-286     DR CATH; 1tis; A:1-286; 
#=GS 1tisA00/1-286     DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus T4; 
#=GS 1tisA00/1-286     DR GO; GO:0004799; 
#=GS 1tisA00/1-286     DR EC; 2.1.1.45; 
#=GS P47469/1-287      AC P47469
#=GS P47469/1-287      OS Mycoplasma genitalium G37
#=GS P47469/1-287      DE Thymidylate synthase
#=GS P47469/1-287      DR ORG; Bacteria; Tenericutes; Mollicutes; Mycoplasmatales; Mycoplasmataceae; Mycoplasma; Mycoplasma genitalium; 
#=GS P47469/1-287      DR EC; 2.1.1.45; 
#=GS Q6QGJ5/1-278      AC Q6QGJ5
#=GS Q6QGJ5/1-278      OS Escherichia virus T5
#=GS Q6QGJ5/1-278      DE Probable thymidylate synthase
#=GS Q6QGJ5/1-278      DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Escherichia virus T5; 
#=GS Q6QGJ5/1-278      DR GO; GO:0004799; 
#=GS Q6QGJ5/1-278      DR EC; 2.1.1.45; 
#=GS A0A221J860/1-278  AC A0A221J860
#=GS A0A221J860/1-278  OS Escherichia phage OSYSP
#=GS A0A221J860/1-278  DE Putative thymidylate synthase
#=GS A0A221J860/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Escherichia phage OSYSP; 
#=GS A0A221J860/1-278  DR EC; 2.1.1.45; 
#=GS A0A023MHZ7/1-278  AC A0A023MHZ7
#=GS A0A023MHZ7/1-278  OS Escherichia phage vB_EcoS_FFH1
#=GS A0A023MHZ7/1-278  DE Putative thymidylate synthase
#=GS A0A023MHZ7/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Escherichia virus FFH1; 
#=GS A0A023MHZ7/1-278  DR EC; 2.1.1.45; 
#=GS A0A193H210/1-278  AC A0A193H210
#=GS A0A193H210/1-278  OS Shigella phage SHSML-45
#=GS A0A193H210/1-278  DE Thymidylate synthase
#=GS A0A193H210/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Shigella phage SHSML-45; 
#=GS A0A0A7RSU7/1-278  AC A0A0A7RSU7
#=GS A0A0A7RSU7/1-278  OS Enterobacteria phage DT571/2
#=GS A0A0A7RSU7/1-278  DE Thymidylate synthase
#=GS A0A0A7RSU7/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Enterobacteria phage DT571/2; 
#=GS A0A0A7RSK2/1-278  AC A0A0A7RSK2
#=GS A0A0A7RSK2/1-278  OS Escherichia virus DT57C
#=GS A0A0A7RSK2/1-278  DE Thymidylate synthase
#=GS A0A0A7RSK2/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Escherichia virus DT57C; 
#=GS A0A0M7RFI0/1-278  AC A0A0M7RFI0
#=GS A0A0M7RFI0/1-278  OS Escherichia phage slur09
#=GS A0A0M7RFI0/1-278  DE Thymidylate synthase 2
#=GS A0A0M7RFI0/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Escherichia virus slur09; 
#=GS A0A2K8GQ34/1-278  AC A0A2K8GQ34
#=GS A0A2K8GQ34/1-278  OS Shigella phage SSP1
#=GS A0A2K8GQ34/1-278  DE Thymidylate synthase
#=GS A0A2K8GQ34/1-278  DR ORG; Viruses; Caudovirales; Siphoviridae; Tequintavirus; Shigella phage SSP1; 
#=GS Q6X186/1-286      AC Q6X186
#=GS Q6X186/1-286      OS Enterobacteria phage T2H
#=GS Q6X186/1-286      DE Td
#=GS Q6X186/1-286      DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Enterobacteria phage T2H; 
#=GS Q7Y4M9/1-286      AC Q7Y4M9
#=GS Q7Y4M9/1-286      OS Enterobacteria phage T2
#=GS Q7Y4M9/1-286      DE dTMP thymidylate synthase
#=GS Q7Y4M9/1-286      DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Enterobacteria phage T2; 
#=GS A0A2Z5WKY6/1-286  AC A0A2Z5WKY6
#=GS A0A2Z5WKY6/1-286  OS Escherichia phage T2
#=GS A0A2Z5WKY6/1-286  DE Thymidylate synthetase
#=GS A0A2Z5WKY6/1-286  DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia phage T2; 
#=GS A0A162EDQ1/1-286  AC A0A162EDQ1
#=GS A0A162EDQ1/1-286  OS Escherichia phage PEC04
#=GS A0A162EDQ1/1-286  DE Putative thymidylate synthase
#=GS A0A162EDQ1/1-286  DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY01; 
#=GS P00471/1-286      AC P00471
#=GS P00471/1-286      OS Escherichia virus T4
#=GS P00471/1-286      DE Thymidylate synthase
#=GS P00471/1-286      DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus T4; 
#=GS P00471/1-286      DR GO; GO:0004799; 
#=GS P00471/1-286      DR EC; 2.1.1.45; 
#=GS A0A0A0PSM3/1-286  AC A0A0A0PSM3
#=GS A0A0A0PSM3/1-286  OS Escherichia phage HY01
#=GS A0A0A0PSM3/1-286  DE Putative thymidylate synthase
#=GS A0A0A0PSM3/1-286  DR ORG; Viruses; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY01; 
#=GF SQ 16
1tisA00/1-286             MKQYQDLIKDIFENGYETDDRTGTGTIALFGSKLRWDLTKGFPAVTTKKLAWKACIAELIWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKL-RPKDF---VLNNYVSHPPIKGKMAV
P47469/1-287              MKQYLDLASYVLANGKKRKNRTDTDTLSVFGYQMKFDLTNSFPLLTTKKVNWKAIVHELLWFIKGDTNIKYL-------VDNGVNIWNEWPYENFKKSPSFQNETLQEFILKVKTDNEFAKQFADLGPVYGKQWRNFNGVDQLKKVIQEIKENPNSRRLIVSSWNPSELEKMALAPCHSLFQFYVEE-DKLSLQLYQRSGDIFLGVPFNIASYALLVYLVAHETKLKPGYFIHTLGDAHIYENHIEQIKLQLTRTTLDPPQVVLKS--------DKSIF---------AYSFDDIELVGYNYHPFIYGRVAV
Q6QGJ5/1-278              MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDK--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRPLPTLVMPEFVDLYDLLENNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A221J860/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDK--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRPLPTLVMPEFVDLYDLLENNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A023MHZ7/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDK--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRPLPTLVMPEFVDLYDLLENNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A193H210/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDN--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHIEQVEEQMKRKPRPLPTLVMPEFVDLYDLLDNNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A0A7RSU7/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLRDGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDN--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRSLPTLVMPEFVDLYDLLENNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A0A7RSK2/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLRDGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDN--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRSLPTLVMPEFVDLYDLLENNTA---------AWSF---HLEGYDPHPALKAKMS-
A0A0M7RFI0/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDR--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYSDHIEQVEEQMKRKPRPLPTLVMPEFVDLYDLLENNTA---------AWSF---QLEGYDPHPALKAKMS-
A0A2K8GQ34/1-278          MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTP-NYEDQAISMGYDR--------------------GNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYSDHIEQVEEQMKRKPRPLPTLVMPEFVDLYDLLENNTA---------AWSF---QLEGYDPHPALKAKMS-
Q6X186/1-286              MKQYQDLIKDIFENGYETDDRTGTGTIALFGTKLRWDLSKGFPAVTTKKLAWKACIAELLWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIVEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYAALVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKL-RPKDF---VLNNYVSHPPIKGKMAV
Q7Y4M9/1-286              MKQYQDLIKDIFENGYETDDRTGTGTIALFGTKLRWDLSKGFPAVTTKKLAWKACIAELLWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIVEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYAALVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKL-RPKDF---VLNNYVSHPPIKGKMAV
A0A2Z5WKY6/1-286          MKQYQDLIKDIFENGYETDDRTGTGTIALFGTKLRWDLSKGFPAVTTKKLAWKACIAELLWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIVEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYAALVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKL-RPKDF---VLNNYVSHPPIKGKMAV
A0A162EDQ1/1-286          MKQYQDLIKDIFENGYETDDRTGTGTIALFGTKLRWDLTKGFPAVTTKKLAWKACIAELIWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYAALVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPMDLCELQLK-FPDEFDEWDTESQVFWLSQFAKPHNF---VLNNYVSHPPIKGKMAV
P00471/1-286              MKQYQDLIKDIFENGYETDDRTGTGTIALFGSKLRWDLTKGFPAVTTKKLAWKACIAELIWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKL-RPKDF---VLNNYVSHPPIKGKMAV
A0A0A0PSM3/1-286          MKQYQDLIKDIFENGYETDDRTGTGTIALFGTKLRWDLTKGFPAVTTKKLAWKACIAELIWFLSGSTNVNDLRLIQHDSLIQGKTVWDE-NYENQAKDLGYHS--------------------GELGPIYGKQWRDFGGVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRN-GYLDLQWYQRSVDVFLGLPFNIASYAALVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPMDLCELQLK-FPDEFDEWDTESQVFWLSQFAKPHNF---VLNNYVSHPPIKGKMAV
#=GC scorecons            969955654775449445579979796669654575994579977999777996475997997797996579644444444453779550799677455785400000000000000000000759997999999697949974769656954965995699799579954999799943795594717797967499979499979999999959587697555949557977796799946969946746595744754775435443543555444101101101635900039559459956768762
#=GC scorecons_70         ****__*__**___*____********__*____*_**__*************__*_***********__***___________***___******___**______________________*_**************_***_***__**__*__**_******_***__*******__**__*_*_*******_*****_************_*_*****___*_*__***********_**_**__*___*_*__*__**____________________________*____*__*__**_**_**__
#=GC scorecons_80         *_**_____*____*____*******___*______**__********_****____**_********__**____________*_*___***__*___**______________________*_***_******_***_***_*_*___*__*__**__*****_***__*******__**__*_*_*_***_*_*****_************_*_**_**___*_*__****_*_****__*_**______*_*__*__*_____________________________*____*__*__**____**__
#=GC scorecons_90         *_**__________*_____**_*_*___*______**___**__***___**____**_**__*_**___*______________*____**_______*________________________***_******_*_*_**____*___*__*__**__**_**__**__***_***___*__*_____*_*___***_*_***_********_*_*__*____*_*___*___*__***__*_**______*_____________________________________*____*__*__**____*___
//