# STOCKHOLM 1.0
#=GF ID 3.30.565.10/FF/000092
#=GF DE DNA topoisomerase 2
#=GF AC 3.30.565.10/FF/000092
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 87.952
#=GS P12531/10-253         AC P12531
#=GS P12531/10-253         OS Trypanosoma brucei brucei
#=GS P12531/10-253         DE DNA topoisomerase 2
#=GS P12531/10-253         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS P12531/10-253         DR GO; GO:0003918; GO:0005634; GO:0005739; GO:0006265; GO:0020023; 
#=GS P12531/10-253         DR EC; 5.6.2.3; 
#=GS Q4QF53/10-254         AC Q4QF53
#=GS Q4QF53/10-254         OS Leishmania major
#=GS Q4QF53/10-254         DE DNA topoisomerase 2
#=GS Q4QF53/10-254         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4QF53/10-254         DR GO; GO:0020023; 
#=GS E2RU90/10-258         AC E2RU90
#=GS E2RU90/10-258         OS Giardia lamblia ATCC 50803
#=GS E2RU90/10-258         DE DNA topoisomerase 2
#=GS E2RU90/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS E9I455/1-200          AC E9I455
#=GS E9I455/1-200          OS Daphnia pulex
#=GS E9I455/1-200          DE Uncharacterized protein
#=GS E9I455/1-200          DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; 
#=GS H3EX83/163-396        AC H3EX83
#=GS H3EX83/163-396        OS Pristionchus pacificus
#=GS H3EX83/163-396        DE Uncharacterized protein
#=GS H3EX83/163-396        DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS O61078/10-254         AC O61078
#=GS O61078/10-254         OS Leishmania chagasi
#=GS O61078/10-254         DE DNA topoisomerase 2
#=GS O61078/10-254         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania chagasi; 
#=GS O61078/10-254         DR EC; 5.6.2.3; 
#=GS F9W9A3/10-253         AC F9W9A3
#=GS F9W9A3/10-253         OS Trypanosoma congolense IL3000
#=GS F9W9A3/10-253         DE DNA topoisomerase 2
#=GS F9W9A3/10-253         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Nannomonas; Trypanosoma congolense; 
#=GS A0A1E1IS39/10-254     AC A0A1E1IS39
#=GS A0A1E1IS39/10-254     OS Leishmania guyanensis
#=GS A0A1E1IS39/10-254     DE DNA topoisomerase 2
#=GS A0A1E1IS39/10-254     DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS A0A1G4I7P1/10-253     AC A0A1G4I7P1
#=GS A0A1G4I7P1/10-253     OS Trypanosoma equiperdum
#=GS A0A1G4I7P1/10-253     DE DNA topoisomerase 2
#=GS A0A1G4I7P1/10-253     DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS A0A3P3Z213/10-254     AC A0A3P3Z213
#=GS A0A3P3Z213/10-254     OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3Z213/10-254     DE DNA topoisomerase 2
#=GS A0A3P3Z213/10-254     DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS E9AQC1/10-255         AC E9AQC1
#=GS E9AQC1/10-255         OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AQC1/10-255         DE DNA topoisomerase 2
#=GS E9AQC1/10-255         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4HWL4/10-254         AC A4HWL4
#=GS A4HWL4/10-254         OS Leishmania infantum
#=GS A4HWL4/10-254         DE DNA topoisomerase 2
#=GS A4HWL4/10-254         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A088RLN4/10-254     AC A0A088RLN4
#=GS A0A088RLN4/10-254     OS Leishmania panamensis
#=GS A0A088RLN4/10-254     DE DNA topoisomerase 2
#=GS A0A088RLN4/10-254     DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9BCH0/10-254         AC E9BCH0
#=GS E9BCH0/10-254         OS Leishmania donovani BPK282A1
#=GS E9BCH0/10-254         DE DNA topoisomerase 2
#=GS E9BCH0/10-254         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A2A6CIK8/1430-1673  AC A0A2A6CIK8
#=GS A0A2A6CIK8/1430-1673  OS Pristionchus pacificus
#=GS A0A2A6CIK8/1430-1673  DE Top-2
#=GS A0A2A6CIK8/1430-1673  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS A4H891/10-254         AC A4H891
#=GS A4H891/10-254         OS Leishmania braziliensis
#=GS A4H891/10-254         DE DNA topoisomerase 2
#=GS A4H891/10-254         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS Q38EZ6/10-253         AC Q38EZ6
#=GS Q38EZ6/10-253         OS Trypanosoma brucei brucei TREU927
#=GS Q38EZ6/10-253         DE DNA topoisomerase 2
#=GS Q38EZ6/10-253         DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS E1F6D4/10-258         AC E1F6D4
#=GS E1F6D4/10-258         OS Giardia lamblia P15
#=GS E1F6D4/10-258         DE DNA topoisomerase 2
#=GS E1F6D4/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS Q86BT9/10-258         AC Q86BT9
#=GS Q86BT9/10-258         OS Giardia intestinalis
#=GS Q86BT9/10-258         DE DNA topoisomerase 2
#=GS Q86BT9/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS V6U3Y3/10-258         AC V6U3Y3
#=GS V6U3Y3/10-258         OS Giardia intestinalis
#=GS V6U3Y3/10-258         DE DNA topoisomerase 2
#=GS V6U3Y3/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS C6LX36/10-258         AC C6LX36
#=GS C6LX36/10-258         OS Giardia intestinalis ATCC 50581
#=GS C6LX36/10-258         DE DNA topoisomerase 2
#=GS C6LX36/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS A0A132NVY7/10-258     AC A0A132NVY7
#=GS A0A132NVY7/10-258     OS Giardia intestinalis assemblage B
#=GS A0A132NVY7/10-258     DE DNA topoisomerase 2
#=GS A0A132NVY7/10-258     DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GS V6TEW0/10-258         AC V6TEW0
#=GS V6TEW0/10-258         OS Giardia intestinalis
#=GS V6TEW0/10-258         DE DNA topoisomerase 2
#=GS V6TEW0/10-258         DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; 
#=GF SQ 23
P12531/10-253                 LTPIEHVLTRPEMYIGSLDTTATPMFIYDEQKGHMVWETVKLNHGLLKIVDEILLNASDNI---SNR--SARMTYIRVTIT-DTGEITIENDGAGIPIVRSREHKLYIPEMVFGHLLTSSNYDDDNQNAVAGRHGYGAKLTNILSLSFSVCC--RTNGREFHMSWQDHMRKATAPRVSNVGTKEKNVTRVKFLPDYERFGMKEKKISNDMKRVLYKRIMDLSAMFPNIQITLNGSSFGFKSFKDYATLYSAM-
Q4QF53/10-254                 LTPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGRMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYINIHIS-DTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVC--RTDGREFHMSWTDHMRMATAPRVNRVDPKEKNVTRVKFMPDYAHFGFPSASISLDMKRVLHKRVMDLAAMFSKIEVRLNNVPFGFRTFTDYAGLYSL--
E2RU90/10-258                 VTGSEHVLLRPDMYVGSVSAAETFLWLYEPGQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAEHKMTYIKCSVDVASGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGQVFEQTWTDNMKNTKPPRIEDVRDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGTELKIANFEQYARMVYRSI
E9I455/1-200                  ----------------------------------MIQREIIYTPGLWKIVDEILINDVRNKDRDPE------MDTIQIDIDPIKNVIKFYYNGKGIPI-------TYIPSMIFDPLLPDFNFYDGEETVTGGLNYYGAKLGNIFSTAFELETASKDLCLRFKQTWTDNMTLAETPVVEPYSG--PNYTKNTFSPDLDKFRM--DSLNKDTIALLSRRAFEVATSTPGVNVYLNDKPLPINNFKEYLDLCLK--
H3EX83/163-396                LTSEEHVLTRPDTYIGSSTITEEEVWLIEDDR--FTRRKASFCPGLIKIVDEILVNAADNKQRDEE------MAEIWVEIDQSTGEISVWNDGRGLPIRPIEEGGSLIPSLVFGCLYTSSNYDDDQERTVGGRNGFGAKLANLYSTRFRVRTAEKESGRMFEQTWYGNMTTHDEPTITNQEGTARDFTEVRFTPDYRRFEMEETGLTPDTLALLRRRLHDLAATVKGVRISLNGERIEQ----------VRN-
O61078/10-254                 LTPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGRMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISIHIS-DTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVC--RTDGRESHMSWTDHMRMATAPRVNRVDPKEKSVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFRTFTDYARLYSL--
F9W9A3/10-253                 LTPIEHVLTRPEMYIGSIDTTPTGMFLYDEEKGHMVWETVKLNHGLLKIVDEILLNASDNI---SNR--SARMTYIRVNIT-DVGEITIENDGAGIPIVRSREHKLYIPEMVFGHLLTSSNYDDDNQNAVAGRHGYGAKLTNILSLNFSVSC--RTNGREFHMSWQDHMKKATAPRVSNVGSKERNITRVKFLPDYERFGMKEKKISSDMKRVLYKRIMDLSAMFPNIQMTLNGTSFGFKSFKEYASLYSTP-
A0A1E1IS39/10-254             LSPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGKMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISISIS-DTGEITVENDGAGLPIVRSREHKIYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVIC--RTAGREFHMSWTDHMRMATAPRVSRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFETFTDYARLYSL--
A0A1G4I7P1/10-253             LTPIEHVLTRPEMYIGSLDTTATPMFIYDEQKGHMVWETVKLNHGLLKIVDEILLNASDNI---SNR--SARMTYIRVTIT-DTGEITIENDGAGIPIVRSREHKLYIPEMVFGHLLTSSNYDDDNQNAVAGRHGYGAKLTNILSLSFSVCC--RTNGREFHMSWQDHMRKATAPRVSNVGTKEKNVTRVKFLPDYERFGMKEKKISNDMKRVLYKRIMDLSAMFPNIQITLNGSSFGFKSFKDYATLYSAM-
A0A3P3Z213/10-254             LSPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGKMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISISIS-DTGEITVENDGAGLPIVRSREHKIYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVIC--RTAGREFHMSWTDHMRMATAPRVSRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFETFTDYARLYSL--
E9AQC1/10-255                 LTPIDHVLLRPEMYVGSIETQPTSMYIFDPEKGKMVWETMRVNQGLLKIVDEILLNAADNI---TNSKGSVRQTYISINIS-DTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVC--RTDGREFHMSWTDHMRMATAPRVNRVDPKEKNVTRVKFMPDYAHFGFPSASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFRSFTDYARLYSLS-
A4HWL4/10-254                 LTPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGRMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISIHIS-DTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVC--RTDGREFHMSWTDHMRMATAPRVNRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFRTFTDYARLYSL--
A0A088RLN4/10-254             LSPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGKMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISISIS-DTGEITVENDGAGLPIVRSREHKIYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVIC--RTAGREFHMSWTDHMRMATAPRVSRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFETFTDYARLYSL--
E9BCH0/10-254                 LTPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGRMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISIHIS-DTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVC--RTDGREFHMSWTDHMRMATAPRVNRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFRTFTDYARLYSL--
A0A2A6CIK8/1430-1673          LTSEEHVLTRPDTYIGSSTITEEEVWLIEDDR--FTRRKASFCPGLIKIVDEILVNAADNKQRDEE------MAEIWVEIDQSTGEISVWNDGRGLPIRPIEEGGSLIPSLVFGCLYTSSNYDDDQERTVGGRNGFGAKLANLYSTRFRVRTAEKESGRMFEQTWYGNMTTHDEPTITNQEGTARDFTEVRFTPDYRRFEMEETGLTPDTLALLRRRLHDLAATVKGVRISLNGERIEMDGLREYAQRCVDS-
A4H891/10-254                 LSPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGKMVWETMRVNQGLLKIVDEILLNAADNI---NNSKGSVRQTYISISIS-DTGEITVENDGAGLPIVRSREHKIYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVIC--RTAGREFHMSWTDHMRMATAPRVSRVDPKEKNVTRVKFMPDYAHFGFPNASISLDMKRVLHKRIMDLAAMFSKIEVRLNNVPFGFETFTDYARLYSL--
Q38EZ6/10-253                 LTPIEHVLTRPEMYIGSLDTTATPMFIYDEQKGHMVWETVKLNHGLLKIVDEILLNASDNI---SNR--SARMTYIRVTIT-DTGEITIENDGAGIPIVRSREHKLYIPEMVFGHLLTSSNYDDDNQNAVAGRHGYGAKLTNILSLSFSVCC--RTNGREFHMSWQDHMRKATAPRVSNVGTKEKNVTRVKFLPDYERFGMKEKKISNDMKRVLYKRIMDLSAMFPNIQITLNGSSFGFKSFKDYATLYSAM-
E1F6D4/10-258                 VTGSEHVLLRPDMYVGSVSAAETFLWLYEPGQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAGHKMSYIKCNVDVVSGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGQVFEQTWTDNMKNTKPPRIEDVKDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNVGLKLIINGTELKIANFEQYARMVYRSI
Q86BT9/10-258                 VTGSEHVLLRPDMYVGSVSAAETFLWLYEPGQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAEHKMTYIKCSVDVASGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGQVFEQTWTDNMKNTKPPRIEDVRDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGTELKIANFEQYARMVYRSI
V6U3Y3/10-258                 VTGSEHVLLRPDMYVGSVSSAETFLWLYNPDQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAGHKMSYIKCDVDVVSGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGRVFEQTWTDNMKNTQSPRIEDVKDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGEELKIANFEQYARMVYRSI
C6LX36/10-258                 VTGSEHVLLRPDMYVGSVSSAETFLWLYNPDQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAGHKMSYIKCDVDVVSGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGRVFEQTWTDNMKNTQSPRIEDVKDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGEELKIANFEQYARMVYRSI
A0A132NVY7/10-258             VTGSEHVLLRPDMYVGSVSSAETFLWLYNPDQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAGHKMSYIKCDVDVVSGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGRVFEQTWTDNMKNTQSPRIEDVKDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGEELKIANFEQYARMVYRSI
V6TEW0/10-258                 VTGSEHVLLRPDMYVGSVSAAETFLWLYEPGQG-LYYTKANIVPGLCKIFDEIIVNASDNKQRDSDRSAEHKMTYIKCSVDVASGAISVENDGVEGLLHFDEKEKMYLPTLAFGILMTSSNYDDTEQRVTGGRNGYGAKLTNIFSTKFTVLL--QENGQVFEQTWTDNMKNTKPPRIEDVRDKKKNFIRFSFTPDYMKFGM-TSGLDRDHAAYMMRRAVDVAGCNIGLKLIINGTELKIANFEQYARMVYRSI
#=GC scorecons                5643677757766767743443635455544551644454444599499699966975794122453223245569444751458595757894646633445465769466984958879856545456697678999979759759483400654764855695769535449674464464675675494997359661345653944547379558676443564536953454534734764544320
#=GC scorecons_70             _*___***_**_**_**___________________________**_**_****_**_**_______________*___*____*_*_*_***_*__*________***_*_**_*_*****_*_____*_**_*********_**_*_*_______**_*___*_*_*_____***_______**_**__*_***__**_____*__*____*_**__***_________**________*__**_______
#=GC scorecons_80             _____***_**__*_**___________________________**_**_***__**_**_______________*___*____*_*___***_____________*_*___**_*_*****_________**_******_**_*__*_*_______*__*___*_*_*_____*__________*_____*_***__*_________*_______*__*_*__________*________*__*________
#=GC scorecons_90             ____________________________________________**_**_***__*___*_______________*__________*____**_______________*___**_*_*__**_________*___*****_*__*__*_*__________*___*___*_____*________________*_**___*_________*_______*__*____________*____________________
//