# STOCKHOLM 1.0
#=GF ID 3.30.230.10/FF/000079
#=GF DE DNA topoisomerase 2
#=GF AC 3.30.230.10/FF/000079
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 48.835
#=GS 1qzrB02/284-418     AC P06786
#=GS 1qzrB02/284-418     OS Saccharomyces cerevisiae S288C
#=GS 1qzrB02/284-418     DE DNA topoisomerase 2
#=GS 1qzrB02/284-418     DR CATH; 1qzr; B:279-405; 
#=GS 1qzrB02/284-418     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1qzrB02/284-418     DR GO; GO:0000019; GO:0000795; GO:0003918; GO:0005515; GO:0005634; GO:0005739; GO:0006265; GO:0006271; GO:0006333; GO:0007131; GO:0031055; GO:0042802; GO:0044774; GO:0097046; GO:0097047; 
#=GS 1qzrB02/284-418     DR EC; 5.6.2.3; 
#=GS 1qzrA02/284-411     AC P06786
#=GS 1qzrA02/284-411     OS Saccharomyces cerevisiae S288C
#=GS 1qzrA02/284-411     DE DNA topoisomerase 2
#=GS 1qzrA02/284-411     DR CATH; 1qzr; A:279-406; 
#=GS 1qzrA02/284-411     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1qzrA02/284-411     DR GO; GO:0000019; GO:0000795; GO:0003918; GO:0005515; GO:0005634; GO:0005739; GO:0006265; GO:0006271; GO:0006333; GO:0007131; GO:0031055; GO:0042802; GO:0044774; GO:0097046; GO:0097047; 
#=GS 1qzrA02/284-411     DR EC; 5.6.2.3; 
#=GS 1pvgB02/284-418     AC P06786
#=GS 1pvgB02/284-418     OS Saccharomyces cerevisiae S288C
#=GS 1pvgB02/284-418     DE DNA topoisomerase 2
#=GS 1pvgB02/284-418     DR CATH; 1pvg; B:279-405; 
#=GS 1pvgB02/284-418     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1pvgB02/284-418     DR GO; GO:0000019; GO:0000795; GO:0003918; GO:0005515; GO:0005634; GO:0005739; GO:0006265; GO:0006271; GO:0006333; GO:0007131; GO:0031055; GO:0042802; GO:0044774; GO:0097046; GO:0097047; 
#=GS 1pvgB02/284-418     DR EC; 5.6.2.3; 
#=GS 1pvgA02/284-418     AC P06786
#=GS 1pvgA02/284-418     OS Saccharomyces cerevisiae S288C
#=GS 1pvgA02/284-418     DE DNA topoisomerase 2
#=GS 1pvgA02/284-418     DR CATH; 1pvg; A:279-406; 
#=GS 1pvgA02/284-418     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1pvgA02/284-418     DR GO; GO:0000019; GO:0000795; GO:0003918; GO:0005515; GO:0005634; GO:0005739; GO:0006265; GO:0006271; GO:0006333; GO:0007131; GO:0031055; GO:0042802; GO:0044774; GO:0097046; GO:0097047; 
#=GS 1pvgA02/284-418     DR EC; 5.6.2.3; 
#=GS P06786/279-406      AC P06786
#=GS P06786/279-406      OS Saccharomyces cerevisiae S288C
#=GS P06786/279-406      DE DNA topoisomerase 2
#=GS P06786/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P06786/279-406      DR GO; GO:0000019; GO:0000795; GO:0003918; GO:0005515; GO:0005634; GO:0005739; GO:0006265; GO:0006271; GO:0006333; GO:0007131; GO:0031055; GO:0042802; GO:0044774; GO:0097046; GO:0097047; 
#=GS P06786/279-406      DR EC; 5.6.2.3; 
#=GS Q6C7Z9/367-496      AC Q6C7Z9
#=GS Q6C7Z9/367-496      OS Yarrowia lipolytica CLIB122
#=GS Q6C7Z9/367-496      DE DNA topoisomerase 2
#=GS Q6C7Z9/367-496      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; 
#=GS Q755V8/285-411      AC Q755V8
#=GS Q755V8/285-411      OS Eremothecium gossypii ATCC 10895
#=GS Q755V8/285-411      DE DNA topoisomerase 2
#=GS Q755V8/285-411      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium; Eremothecium gossypii; 
#=GS R9XL70/285-411      AC R9XL70
#=GS R9XL70/285-411      OS Saccharomycetaceae sp. 'Ashbya aceri'
#=GS R9XL70/285-411      DE DNA topoisomerase 2
#=GS R9XL70/285-411      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomycetaceae sp. 'Ashbya aceri'; 
#=GS J8PZX9/279-406      AC J8PZX9
#=GS J8PZX9/279-406      OS Saccharomyces arboricola H-6
#=GS J8PZX9/279-406      DE DNA topoisomerase 2
#=GS J8PZX9/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces arboricola; 
#=GS J6EDE8/348-475      AC J6EDE8
#=GS J6EDE8/348-475      OS Saccharomyces kudriavzevii IFO 1802
#=GS J6EDE8/348-475      DE DNA topoisomerase 2
#=GS J6EDE8/348-475      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces kudriavzevii; 
#=GS A0A0L8VIX7/279-406  AC A0A0L8VIX7
#=GS A0A0L8VIX7/279-406  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VIX7/279-406  DE DNA topoisomerase 2
#=GS A0A0L8VIX7/279-406  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS E9P8G9/279-406      AC E9P8G9
#=GS E9P8G9/279-406      OS Saccharomyces cerevisiae
#=GS E9P8G9/279-406      DE DNA topoisomerase 2
#=GS E9P8G9/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E9P8H2/279-406      AC E9P8H2
#=GS E9P8H2/279-406      OS Saccharomyces cerevisiae
#=GS E9P8H2/279-406      DE DNA topoisomerase 2
#=GS E9P8H2/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS Q7LMA0/279-406      AC Q7LMA0
#=GS Q7LMA0/279-406      OS Saccharomyces cerevisiae
#=GS Q7LMA0/279-406      DE DNA topoisomerase 2
#=GS Q7LMA0/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS G2WM16/279-406      AC G2WM16
#=GS G2WM16/279-406      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2WM16/279-406      DE DNA topoisomerase 2
#=GS G2WM16/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E9P8H4/279-406      AC E9P8H4
#=GS E9P8H4/279-406      OS Saccharomyces cerevisiae
#=GS E9P8H4/279-406      DE DNA topoisomerase 2
#=GS E9P8H4/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C8ZGE3/279-406      AC C8ZGE3
#=GS C8ZGE3/279-406      OS Saccharomyces cerevisiae EC1118
#=GS C8ZGE3/279-406      DE DNA topoisomerase 2
#=GS C8ZGE3/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E9P8H0/279-406      AC E9P8H0
#=GS E9P8H0/279-406      OS Saccharomyces cerevisiae
#=GS E9P8H0/279-406      DE DNA topoisomerase 2
#=GS E9P8H0/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1NXH6/279-406      AC N1NXH6
#=GS N1NXH6/279-406      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1NXH6/279-406      DE DNA topoisomerase 2
#=GS N1NXH6/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A6ZRZ2/279-406      AC A6ZRZ2
#=GS A6ZRZ2/279-406      OS Saccharomyces cerevisiae YJM789
#=GS A6ZRZ2/279-406      DE DNA topoisomerase 2
#=GS A6ZRZ2/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LNU7/279-406      AC B3LNU7
#=GS B3LNU7/279-406      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LNU7/279-406      DE DNA topoisomerase 2
#=GS B3LNU7/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E9P8H7/279-406      AC E9P8H7
#=GS E9P8H7/279-406      OS Saccharomyces cerevisiae
#=GS E9P8H7/279-406      DE DNA topoisomerase 2
#=GS E9P8H7/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E9P8H8/279-406      AC E9P8H8
#=GS E9P8H8/279-406      OS Saccharomyces cerevisiae
#=GS E9P8H8/279-406      DE DNA topoisomerase 2
#=GS E9P8H8/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C7GUN8/279-406      AC C7GUN8
#=GS C7GUN8/279-406      OS Saccharomyces cerevisiae JAY291
#=GS C7GUN8/279-406      DE DNA topoisomerase 2
#=GS C7GUN8/279-406      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A0A1D8NG10/367-496  AC A0A1D8NG10
#=GS A0A1D8NG10/367-496  OS Yarrowia lipolytica
#=GS A0A1D8NG10/367-496  DE DNA topoisomerase 2
#=GS A0A1D8NG10/367-496  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; 
#=GF SQ 25
1qzrB02/284-418             ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADANEENALK
1qzrA02/284-411             ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
1pvgB02/284-418             ILYERINNRWEVAFAVSDISFQQISFVNSIATTXGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNXFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIX-KTDLATRXFEIADANEENALK
1pvgA02/284-418             ILYERINNRWEVAFAVSDISFQQISFVNSIATTXGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNXFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIX-KTDLATRXFEIADANEENALK
P06786/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
Q6C7Z9/367-496              IVHEIVNDRWEVAFAVSDGTYQNVSFVNSIATTSGGTHVNYIADQLVAKLTATAKKKLKDAQVKPAQLKANMFIFINCLIENPAFTSQTKEQMTTKVSAFGSKCELSDKFIKQVTNNTDIMERVLSIAGR-------
Q755V8/285-411              ILYEKVNDRWELGFAVSDISFQQISFVNSIATTSGGTHVNYLTDQIVKKVSELLSKK--KKTVKPFQIRNNIFIFINCLIENPAFTSQTKEQLTTRVRDFGSKCEVSSDFINKIM-KTELATKIFEIADE-------
R9XL70/285-411              ILYEKVNDRWELGFAVSDISFQQISFVNSIATTSGGTHVNYVTDQIVKKVSELLSKK--KKTVKPFQIRNNIFIFINCLIENPAFTSQTKEQLTTRVRDFGSKCEVSSDFINKIM-KTELATKIFEIADE-------
J8PZX9/279-406              ILYERINERWEVAFAVSDISFQQISFVNSIATTMGGTHVNYVTDQIVRKISDLLKKK-NKKSVKPFQIKNNMFIFINCLVENPAFTSQTKEQLTTRVKDFGSRCEIPNEYINKIM-KTDLAIKMFEIADA-------
J6EDE8/348-475              ILYERLNDRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYVTDQIVKKISEILKKK-KKRSVKPFQIKNNMFIFINCLVENPAFTSQTKEQLTTRVKDFGSRCEIPIEYINKIM-KTELATRMFEIADA-------
A0A0L8VIX7/279-406          ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8G9/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKILEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8H2/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
Q7LMA0/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
G2WM16/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8H4/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
C8ZGE3/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8H0/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
N1NXH6/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
A6ZRZ2/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
B3LNU7/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8H7/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
E9P8H8/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
C7GUN8/279-406              ILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKK-KKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM-KTDLATRMFEIADA-------
A0A1D8NG10/367-496          IVHEIVNDRWEVAFAVSDGTYQNVSFVNSIATTSGGTHVNYIADQLVAKLTATAKKKLKDAQVKPAQLKANMFIFINCLIENPAFTSQTKEQMTTKVSAFGSKCELSDKFIKQVTNNTDIMERVLSIAGR-------
#=GC scorecons              97795696999779999956796799999999949999999779979696665679906665996597869699999998999999999999799795699979966467967740697765747699650000000
#=GC scorecons_70           ****_**_**********_**************_*************_***___***__*__**__*****_*************************__*******___*****__****__*_*_***________
#=GC scorecons_80           *_**__*_**********__**_**********_********_**_*_*_____***_____**__*_*_*_*************************__***_**____**__*___**___*___**_________
#=GC scorecons_90           *__*__*_***__*****___*__*********_*******__**_*_*______**_____**__*_*_*_********************_**_*__***_**_____*______*________**_________
//