# STOCKHOLM 1.0
#=GF ID 3.30.230.10/FF/000110
#=GF DE DNA topoisomerase 2
#=GF AC 3.30.230.10/FF/000110
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 43.636
#=GS P12531/269-382      AC P12531
#=GS P12531/269-382      OS Trypanosoma brucei brucei
#=GS P12531/269-382      DE DNA topoisomerase 2
#=GS P12531/269-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS P12531/269-382      DR GO; GO:0003918; GO:0005634; GO:0005739; GO:0006265; GO:0020023; 
#=GS P12531/269-382      DR EC; 5.6.2.3; 
#=GS Q4QF53/266-382      AC Q4QF53
#=GS Q4QF53/266-382      OS Leishmania major
#=GS Q4QF53/266-382      DE DNA topoisomerase 2
#=GS Q4QF53/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4QF53/266-382      DR GO; GO:0020023; 
#=GS O61078/266-382      AC O61078
#=GS O61078/266-382      OS Leishmania chagasi
#=GS O61078/266-382      DE DNA topoisomerase 2
#=GS O61078/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania chagasi; 
#=GS O61078/266-382      DR EC; 5.6.2.3; 
#=GS F9W9A3/267-383      AC F9W9A3
#=GS F9W9A3/267-383      OS Trypanosoma congolense IL3000
#=GS F9W9A3/267-383      DE DNA topoisomerase 2
#=GS F9W9A3/267-383      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Nannomonas; Trypanosoma congolense; 
#=GS A0A088RLN4/266-385  AC A0A088RLN4
#=GS A0A088RLN4/266-385  OS Leishmania panamensis
#=GS A0A088RLN4/266-385  DE DNA topoisomerase 2
#=GS A0A088RLN4/266-385  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS A0A1G4I7P1/269-382  AC A0A1G4I7P1
#=GS A0A1G4I7P1/269-382  OS Trypanosoma equiperdum
#=GS A0A1G4I7P1/269-382  DE DNA topoisomerase 2
#=GS A0A1G4I7P1/269-382  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS A4H891/266-382      AC A4H891
#=GS A4H891/266-382      OS Leishmania braziliensis
#=GS A4H891/266-382      DE DNA topoisomerase 2
#=GS A4H891/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS E9AQC1/266-382      AC E9AQC1
#=GS E9AQC1/266-382      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AQC1/266-382      DE DNA topoisomerase 2
#=GS E9AQC1/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4HWL4/266-382      AC A4HWL4
#=GS A4HWL4/266-382      OS Leishmania infantum
#=GS A4HWL4/266-382      DE DNA topoisomerase 2
#=GS A4HWL4/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A1E1IS39/266-385  AC A0A1E1IS39
#=GS A0A1E1IS39/266-385  OS Leishmania guyanensis
#=GS A0A1E1IS39/266-385  DE DNA topoisomerase 2
#=GS A0A1E1IS39/266-385  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS E9BCH0/266-382      AC E9BCH0
#=GS E9BCH0/266-382      OS Leishmania donovani BPK282A1
#=GS E9BCH0/266-382      DE DNA topoisomerase 2
#=GS E9BCH0/266-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A3P3Z213/266-382  AC A0A3P3Z213
#=GS A0A3P3Z213/266-382  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3Z213/266-382  DE DNA topoisomerase 2
#=GS A0A3P3Z213/266-382  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS Q38EZ6/269-382      AC Q38EZ6
#=GS Q38EZ6/269-382      OS Trypanosoma brucei brucei TREU927
#=GS Q38EZ6/269-382      DE DNA topoisomerase 2
#=GS Q38EZ6/269-382      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GF SQ 13
P12531/269-382              -----KSGCVAFIPSVVPGVRRMFGVVNGVVTYNGGTHCNAAQDILTGCLDGVERELKKENKVMDTNRVLRHFTILVFLVQVQPKFDSQNKARLVSTPTMPRVPRQDVMKYLLRMPFLE-
Q4QF53/266-382              FVYTSPNGSVAYVPQLTQSPKRIVSVVNGVVTYNGGTHCNAAMDILDACLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLVQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLERMPF---
O61078/266-382              FVYTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAMDILDSCLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLIQTQPKFDSQSKARLVSTVTMPRMPKNTLEKYLERMPF---
F9W9A3/267-383              ---ESRSGCVAFIPSVTPGVRRMFGVVNGVVTYNGGTHCNAAQEILVGCLDGVEKELKKENKVMDSNRVLRHFTILVFLVQVQPKFDSQNKARLISAPTMPRVPRQDVMKYLLRMPFLES
A0A088RLN4/266-385          FVHTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAIDILDSCLDSLSRNFKKEGKVVDTNRVQRHFTVLVFLIQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLEKMPFLEA
A0A1G4I7P1/269-382          -----KSGCVAFIPSVVPGVRRMFGVVNGVVTYNGGTHCNAAQDILTGCLDGVERELKKENKVMDTNRVLRHFTILVFLVQVQPKFDSQNKARLVSTPTMPRVPRQDVMKYLLRMPFLE-
A4H891/266-382              FVHTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAIDILDSCLDSLSRNFKKEGKVVDTNRVQRHFTVLVFLIQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLETMPF---
E9AQC1/266-382              FVYTSSNGSVAYVPQLTQSPKRIVSVVNGVVTYNGGTHCNAAMDILDSCLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLVQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLERMPF---
A4HWL4/266-382              FVYTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAMDILDSCLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLIQTQPKFDSQSKARLVSTVTMPRVPKNTLEKYLERMPF---
A0A1E1IS39/266-385          FVHTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAIDILDSCLDSLSRNFKKEGKVVDTNRVQRHFTVLVFLIQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLEKMPFLEA
E9BCH0/266-382              FVYTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAMDILDSCLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLIQTQPKFDSQSKARLVSTVTMPRVPKNTLEKYLERMPF---
A0A3P3Z213/266-382          FVHTSPNGSVAYVPQLTQSPKRIVGVVNGVVTYNGGTHCNAAIDILDSCLDSLSRNFKKEGKVVDTNRVQRHFTVLVFLIQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLETMPF---
Q38EZ6/269-382              -----KSGCVAFIPSVVPGVRRMFGVVNGVVTYNGGTHCNAAQDILTGCLDGVERELKKENKVMDTNRVLRHFTILVFLVQVQPKFDSQNKARLVSTPTMPRVPRQDVMKYLLRMPFLE-
#=GC scorecons              222234696997795665657965799999999999999999489945999665766996599697999599997999979599999996999989759999897556499946999220
#=GC scorecons_70           _______*_*****_*____***_******************_***__***_*_*_****_********_***********_*******_*******_*******__*_***_****___
#=GC scorecons_80           _______*_***_*_______*__******************_***__***______**__**_*****_****_****_*_*******_*******_******_____***__***___
#=GC scorecons_90           _______*_**__*_______*___*****************_***__***______**__**_*_***_****_****_*_*******_******__******_____***__***___
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