# STOCKHOLM 1.0 #=GF ID 3.30.230.10/FF/000101 #=GF DE Phosphomevalonate kinase #=GF AC 3.30.230.10/FF/000101 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 84.936 #=GS P24521/5-270 AC P24521 #=GS P24521/5-270 OS Saccharomyces cerevisiae S288C #=GS P24521/5-270 DE Phosphomevalonate kinase #=GS P24521/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS P24521/5-270 DR GO; GO:0004631; GO:0005634; GO:0005737; GO:0006696; GO:0010142; GO:0019287; GO:0031388; #=GS P24521/5-270 DR EC; 2.7.4.2; #=GS Q38F36/1-74_112-294 AC Q38F36 #=GS Q38F36/1-74_112-294 OS Trypanosoma brucei brucei TREU927 #=GS Q38F36/1-74_112-294 DE Phosphomevalonate kinase protein, putative #=GS Q38F36/1-74_112-294 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38F36/1-74_112-294 DR GO; GO:0005524; #=GS Q54CW0/1-163_194-314 AC Q54CW0 #=GS Q54CW0/1-163_194-314 OS Dictyostelium discoideum #=GS Q54CW0/1-163_194-314 DE Uncharacterized protein #=GS Q54CW0/1-163_194-314 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS F0Z9J1/2-163_194-318 AC F0Z9J1 #=GS F0Z9J1/2-163_194-318 OS Dictyostelium purpureum #=GS F0Z9J1/2-163_194-318 DE Uncharacterized protein #=GS F0Z9J1/2-163_194-318 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS Q6C6U3/1-247 AC Q6C6U3 #=GS Q6C6U3/1-247 OS Yarrowia lipolytica CLIB122 #=GS Q6C6U3/1-247 DE Phosphomevalonate kinase #=GS Q6C6U3/1-247 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS Q756B3/2-268 AC Q756B3 #=GS Q756B3/2-268 OS Eremothecium gossypii ATCC 10895 #=GS Q756B3/2-268 DE Phosphomevalonate kinase #=GS Q756B3/2-268 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium; Eremothecium gossypii; #=GS H0GLC6/5-270 AC H0GLC6 #=GS H0GLC6/5-270 OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 #=GS H0GLC6/5-270 DE Phosphomevalonate kinase #=GS H0GLC6/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; #=GS A0A0L8VJB8/5-270 AC A0A0L8VJB8 #=GS A0A0L8VJB8/5-270 OS Saccharomyces sp. 'boulardii' #=GS A0A0L8VJB8/5-270 DE Phosphomevalonate kinase #=GS A0A0L8VJB8/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; #=GS A0A371CC19/1-247 AC A0A371CC19 #=GS A0A371CC19/1-247 OS Yarrowia lipolytica #=GS A0A371CC19/1-247 DE Phosphomevalonate kinase #=GS A0A371CC19/1-247 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS A0A1D8NHC5/8-257 AC A0A1D8NHC5 #=GS A0A1D8NHC5/8-257 OS Yarrowia lipolytica #=GS A0A1D8NHC5/8-257 DE Phosphomevalonate kinase #=GS A0A1D8NHC5/8-257 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS B3LMA8/5-270 AC B3LMA8 #=GS B3LMA8/5-270 OS Saccharomyces cerevisiae RM11-1a #=GS B3LMA8/5-270 DE Phosphomevalonate kinase #=GS B3LMA8/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS N1NXL3/5-270 AC N1NXL3 #=GS N1NXL3/5-270 OS Saccharomyces cerevisiae CEN.PK113-7D #=GS N1NXL3/5-270 DE Phosphomevalonate kinase #=GS N1NXL3/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS A6ZMT2/5-270 AC A6ZMT2 #=GS A6ZMT2/5-270 OS Saccharomyces cerevisiae YJM789 #=GS A6ZMT2/5-270 DE Phosphomevalonate kinase #=GS A6ZMT2/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS G2WKS7/5-270 AC G2WKS7 #=GS G2WKS7/5-270 OS Saccharomyces cerevisiae Kyokai no. 7 #=GS G2WKS7/5-270 DE Phosphomevalonate kinase #=GS G2WKS7/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C8ZF84/5-270 AC C8ZF84 #=GS C8ZF84/5-270 OS Saccharomyces cerevisiae EC1118 #=GS C8ZF84/5-270 DE Phosphomevalonate kinase #=GS C8ZF84/5-270 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GF SQ 15 P24521/5-270 ----RAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKSG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLAQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVDEEDWNITIKSNHLPSGLTLWMGD--- Q38F36/1-74_112-294 ---MVVASCPGKVLILGGYLIVEEPNVGISVGTTARFVTRVA---SWKKCSDGKCR-----------------VHIVSSQFNKEFTFECAAEEDS-----------------------------------------------------DSTLELLADNDFYSQRNYLESQGKPVTAANLRLIPRYTPLLGEVSKTGLGSSAAMTTSVVACLLQLYVFDSKKNNATESVERAPELPLRLEDVTEFIHRISQVAHCVAQGKVGSGFDVYTATFGTCVYRRFSARVLEKLVKGNEPPKRVTIPLLRECVETDEVWVQRIPFRLPTGLQLLLGDVHK Q54CW0/1-163_194-314 -MERVVCSAPGKVLVTGGYLVLDKKYDGIVFTIDSRFYTTIEGSLKPESSSSSPSNNKETLTSSFETLEYLTDINVISPQFHSSQTYHIYYNKSNENKSYQLKPFG-NENYRENKYVENTIIYSLITLSEYKNQTTES-FNKLISSYQLISITIVGDNGFYSQIPQ---------------------------KTGLGSSAALVSSLTASLLSFFGAIDLENQK----------------DKTVLHNLAQVAHCIAQGKIGSGFDISSAVFGSQVYRRFSPELINDILKLYDSKLYPNSKELLKCISETEWDNKHLDMGLPRGLHLLLAD--- F0Z9J1/2-163_194-318 ENKKIICSSPGKVLVTGGYLVLDKKYDGIVFTIDSRFFTTVEG---IEKTTSKSTHEKDILTKSYENLEFVTDINVISPQFHSSQKYHLYYNKQNQNKLYELVPFD-NENYRENKYVENTILYSLLTMSAIENENDQSQFNNKASKYQLINITIVGDNGFYSQIPQ---------------------------KTGLGSSAALVSSLTAALLSFFNIVELENKSDSN---------KLLADKTLLHNLAQISHCIAQGKIGSGFDISSAVFGSQVYRRFSPEIIQSILKLYDSKLYPNPKELLEIIKSNDWDNKHLDMGLPIGLKLL------ Q6C6U3/1-247 ---MTTYSAPGKALLCGGYLVIDPAYSAYVVGLSARIYATVS---ASEASTTS--------------------VHVVSPQFDKGEWTYNY---TN----GQLTAIG--HNPFAHAAVNTVLHYVPP-------RN------------LHINISIKSDNAYHSQIDSTQ----------RGQFAYHKKAIHEVPKTGLGSSAALTTVLVAALLKSYGIDPLHNT-------------------HLVHNLSQVAHCSAQKKIGSGFDVASAVCGSLVYRRFPAESVNMVIAAEGTSEY--GALLRTTVNQ-KWKVTLEPSFLPPGISLLMGDVQG Q756B3/2-268 -DKVRAFSAPGKALLVGGYLVLDPNYKSYVVALSSRMHAVVK---QTEGSAEAPLR-----------------VKLTSSQFNNDQWEYTVDFESN----YELVETKGRRHPFIEKTLANVLNYFQPPRGQLA----------------EISIEVFSDAGYHSQLDSIEHRNE------FRSFRFHKKSITDVPKTGLGSSAGLVTVLTAALISVF-LPEMDVR--------------LNKHLELIHNLSQVAHCQAQGKVGSGFDVASAVFGSIIYQRFPPALINDLPSI-GAPEY--ADCLRNVIDKADWHSRHDRVSLPKGLRIAMGDVR- H0GLC6/5-270 ----RAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVDEEDWNITIKSNHLPSGLTLWMGD--- A0A0L8VJB8/5-270 ----RAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVDEEDWNITIKSNHLPSGLTLWMGD--- A0A371CC19/1-247 ---MTTYSAPGKALLCGGYLVIDPAYSAYVVGLSARIYATVS---ASEASTTS--------------------VHVVSPQFDKGEWTYNY---TN----GQLTAIG--HNPFAHAAVNTVLHYVPP-------RN------------LHINISIKSDNAYHSQIDSTQ----------RGQFAYHKKAIHEVPKTGLGSSAALTTVLVAALLKSYGIDPLHNT-------------------HLVHNLSQVAHCSAQKKIGSGFDVASAVCGSLVYRRFPAESVNMVIAAEGTSEY--GALLRTTVNQ-KWKVTLEPSFLPPGISLLMGDVQG A0A1D8NHC5/8-257 KHEMTTYSAPGKALLCGGYLVIDPAYSAYVVGLSARIYATVS---ASEASTTS--------------------VHVVSPQFDKGEWTYNY---TN----GQLTAIG--HNPFAHAAVNTVLHYVPP-------RN------------LHINISIKSDNAYHSQIDSTQ----------RGQFAYHKKAIHEVPKTGLGSSAALTTVLVAALLKSYGIDPLHNT-------------------HLVHNLSQVAHCSAQKKIGSGFDVASAVCGSLVYRRFPAESVNMVIAAEGTSEY--GALLRTTVNQ-KWKVTLEPSFLPPGISLLMGDVQG B3LMA8/5-270 ----RAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVDEEDWNITIKSNHLPSGLTLWMGD--- N1NXL3/5-270 ----RAFSAPGKALLAGGYLVLDPKYEAFVVGLSARMHAVAHPYGSLQESDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVNEEDWNITIKSNHLPSGLTLWMGD--- A6ZMT2/5-270 ----RAFSAPGKALLAGGYLVLDPKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDEYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVNEEDWNITIKSNHLPSGLTLWMGD--- G2WKS7/5-270 ----RAFSAPGKALLAGGYLVLDPKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVNEEDWNITIKSNHLPSGLTLWMGD--- C8ZF84/5-270 ----RAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFE-------------------VRVKSKQFKDGEWLYHISPKTG----FIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRN-------------LFVIDIFSDDAYHSQEDSVTEHRG------NRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFF-VSDLENN--------------VDKYREVIHNLSQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDI-GSATY--GSKLAHLVDEEDWNITIKSNHLPSGLTLWMGD--- #=GC scorecons 000135496999696399998684474557666569556453111335464432000000000000000000075749499445543634223450000334434512364434435355427324222221244000000000000045474736955779935532111100000023232342324255499999999686757666955471534657400000000000000222224569776987993996979999975595597349899664464364440654370044394437442573453343399397384567100 #=GC scorecons_70 _______********_*******__*___**___**__*__________*_______________________*_*_*_**_________________________________________*____________________________*_*__*__****______________________________********_*_*_*_***___*____*_*_______________________*********_***********__*__**__******__*___________*_____*___*____*________**_**_*___*___ #=GC scorecons_80 _______*_***_*__*****_*__*___*_____*_____________________________________*_*_*_**______________________________________________________________________*_*__*__****______________________________********_*___*___*___*______*_______________________***_*****_**_********__*__**__****________________*_____*___*_____________**_*__*_______ #=GC scorecons_90 _______*_***_*__*****_*____________*_________________________________________*_**___________________________________________________________________________*____**______________________________********_________*__________________________________*___**_**_**_*_*****___*__*___****______________________*_________________**_*__*_______ //