The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Porphobilinogen deaminase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Porphobilinogen deaminase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hydroxymethylbilane synthase activity GO:0004418
Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+).
14 Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS)
(4 more)
Uroporphyrinogen-III synthase activity GO:0004852
Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.
14 Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA)
(4 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Porphyrin-containing compound biosynthetic process GO:0006779
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
14 Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS) Q8I5V3 (/ISS)
(4 more)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
14 Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA)
(4 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
14 Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA) Q8I5V3 (/IDA)
(4 more)
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