# STOCKHOLM 1.0
#=GF ID 3.30.1360.170/FF/000004
#=GF DE Flavin-dependent thymidylate synthase
#=GF AC 3.30.1360.170/FF/000004
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 82.494
#=GS Q5JI17/1-202      AC Q5JI17
#=GS Q5JI17/1-202      OS Thermococcus kodakarensis KOD1
#=GS Q5JI17/1-202      DE Flavin-dependent thymidylate synthase
#=GS Q5JI17/1-202      DR ORG; Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus; Thermococcus kodakarensis; 
#=GS Q5JI17/1-202      DR EC; 2.1.1.148; 
#=GS Q980H6/4-201      AC Q980H6
#=GS Q980H6/4-201      OS Saccharolobus solfataricus P2
#=GS Q980H6/4-201      DE Flavin-dependent thymidylate synthase
#=GS Q980H6/4-201      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS Q980H6/4-201      DR EC; 2.1.1.148; 
#=GS Q748A9/1-201      AC Q748A9
#=GS Q748A9/1-201      OS Geobacter sulfurreducens PCA
#=GS Q748A9/1-201      DE Flavin-dependent thymidylate synthase
#=GS Q748A9/1-201      DR ORG; Bacteria; Proteobacteria; delta/epsilon subdivisions; Deltaproteobacteria; Desulfuromonadales; Geobacteraceae; Geobacter; Geobacter sulfurreducens; 
#=GS Q748A9/1-201      DR EC; 2.1.1.148; 
#=GS B8E000/1-199      AC B8E000
#=GS B8E000/1-199      OS Dictyoglomus turgidum DSM 6724
#=GS B8E000/1-199      DE Flavin-dependent thymidylate synthase
#=GS B8E000/1-199      DR ORG; Bacteria; Dictyoglomi; Dictyoglomia; Dictyoglomales; Dictyoglomaceae; Dictyoglomus; Dictyoglomus turgidum; 
#=GS A5I7M6/1-217      AC A5I7M6
#=GS A5I7M6/1-217      OS Clostridium botulinum A str. Hall
#=GS A5I7M6/1-217      DE Flavin-dependent thymidylate synthase
#=GS A5I7M6/1-217      DR ORG; Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium botulinum; 
#=GS B5YKN7/3-213      AC B5YKN7
#=GS B5YKN7/3-213      OS Thermodesulfovibrio yellowstonii DSM 11347
#=GS B5YKN7/3-213      DE Flavin-dependent thymidylate synthase
#=GS B5YKN7/3-213      DR ORG; Bacteria; Nitrospirae; Nitrospira; Nitrospirales; Nitrospiraceae; Thermodesulfovibrio; Thermodesulfovibrio yellowstonii; 
#=GS D0KS14/4-201      AC D0KS14
#=GS D0KS14/4-201      OS Saccharolobus solfataricus 98/2
#=GS D0KS14/4-201      DE Flavin-dependent thymidylate synthase
#=GS D0KS14/4-201      DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS D0KS14/4-201      DR EC; 2.1.1.148; 
#=GS A0A0E3KBE2/4-201  AC A0A0E3KBE2
#=GS A0A0E3KBE2/4-201  OS Saccharolobus solfataricus
#=GS A0A0E3KBE2/4-201  DE Flavin-dependent thymidylate synthase
#=GS A0A0E3KBE2/4-201  DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; 
#=GS A0A0E3KBE2/4-201  DR EC; 2.1.1.148; 
#=GS A0A175LSJ7/1-215  AC A0A175LSJ7
#=GS A0A175LSJ7/1-215  OS Clostridium botulinum B2 433
#=GS A0A175LSJ7/1-215  DE Flavin-dependent thymidylate synthase
#=GS A0A175LSJ7/1-215  DR ORG; Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium botulinum; 
#=GS A0A0E1QKU6/1-215  AC A0A0E1QKU6
#=GS A0A0E1QKU6/1-215  OS Clostridium botulinum
#=GS A0A0E1QKU6/1-215  DE Flavin-dependent thymidylate synthase
#=GS A0A0E1QKU6/1-215  DR ORG; Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium botulinum; 
#=GF SQ 10
Q5JI17/1-202              MDNGIRVKLVNYTKKPLETVTWAALISYWDEWETETFGRMSDKDVEMHLPRVLGYGHESILEHATLTFAIEGCSRVCSHQLVRHRLASYTQQSQRYIVLNPEDVEETFVIPSGIKEDPELLAEWKELMKKSIELY----KKSVERGQHQE------------DARFILPQAVRTKIVVTMNLRELKHFLGLRACERAQWEIREVAWKMLEEIAKNDEL------
Q980H6/4-201              ------VKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKP--IDEYYKPIIPPSAKKRS--KELVEKAYKEAYDNY----YTLLESGVPEE------------DARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTG
Q748A9/1-201              ----MKIALLQHTPDPEAAVALAARLCYASVGIDELREKLSASDVTAFLDKIMSLGHQSVLEHASFTFGIEGISRAASHQLVRHRIASYSQQSQRYVTF--RGDGFPRVVPGSVSATEKRRQVFESAMQACADAY----RALVDDGVPAE------------DARFVLPNAAETKIIVTMNARELIHFFGLRCCERAQWEIRALAVEMLRLVKGVAPTIFRDA-
B8E000/1-199              ----MKVKLISYTPEPEKVCALAMRLCHYQGSIEELEEKLTPEEIVRLLNKAKKLQHMSIFEHASFTFYIEGVSRVTTHQLVRHRIASYSQQSQRYVKI--KD---EYVIPETIKKEEQRLNVYRDLIERAFDAY----EELVKLGVPKE------------DARYLLPQAIESKIIVTMNARELMHFFTLRTCNSAQWEIRELAWKMLELVRNVAPTIFSDAG
A5I7M6/1-217              M--IMKVKLLEYTPNAEKLIASAAKLCYSSSGIENLQNNLDKEKVDKFLNMLMSYGHESPIEHVSFTFGIEGVSRSLTHQLVRHRIGSYSQQSQRYVRL----DQFEYVIPPSVEKDEEAKNIYIKTMKNCQKSYDDIASILKEKYINNGLRDIDAEKKAIEDARYVFPNACTSKIIVTMNARSLMNFFRHRCCNRAQWEIRELAEIMLFEVKDVAPTLFKYC-
B5YKN7/3-213              -EASLKVSILTHTPEPENVVALSARLCYSPVGIEELKEKLSDNDKDNLINLLINSGHLSPFEHASFTFAVEGISRACSHQLVRHRIASYSQQSQRYVSE---EKGFDYIIPDTIKKDSEIQSLFIEAMKKSHEYYCKILHALEKQGLKGEL--------ARQDARFVLPNAAETKIVITMNARELLHFFKVRCCNRAQWEIRELATEMLKLVKKIAPRLFKNA-
D0KS14/4-201              ------VKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKP--IDEYYKPIIPPSAKKRS--KELVEKAYKEAYDNY----YTLLESGVPEE------------DARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTG
A0A0E3KBE2/4-201          ------VKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKP--IDEYYKPIIPPSAKKRS--KELVEKAYKEAYDNY----YTLLESGVPEE------------DARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTG
A0A175LSJ7/1-215          ----MKVKLLEYTPNAEKLIASAAKLCYSSSGIENLQNNLDKEKVDKFLNMLMSYGHESPIEHVSFTFGIEGVSRSLTHQLVRHRIGSYSQQSQRYVRL----DQFEYVIPPSVEKDEEAKNIYIKTMKNCQKSYDDIASILKEKYINNGLRDIDAEKKAIEDARYVFPNACTSKIIVTMNARSLMNFFRHRCCNRAQWEIRELAEIMLFEVKDVAPTLFKYC-
A0A0E1QKU6/1-215          ----MKVKLLEYTPNAEKLIASAAKLCYSSSGIENLQNNLDKEKVDKFLNMLMSYGHESPIEHVSFTFGIEGVSRSLTHQLVRHRIGSYSQQSQRYVRL----DQFEYVIPPSVEKDEEAKNIYIKTMKNCQKSYDDIASILKEKYINNGLRDIDAEKKAIEDARYVFPNACTSKIIVTMNARSLMNFFRHRCCNRAQWEIRELAEIMLFEVKDVAPTLFKYC-
#=GC scorecons            00003386754794546555737756655336354434464445553364345347729459945699489659943699999997699695979754300133244478945556443144443544744353900103373635543610000000010099977696644669789997969369735939579999995693499348646474565331
#=GC scorecons_70         ______***__**___*___*_**_*_____________*________*______**_*__**__***_***_**___***********_*_****____________***____*____________*_____*______*_*_____*____________*********___*********_*__**__*_*_*******__*__**__**_*_*__*____
#=GC scorecons_80         ______*_*__**_______*_**_______________________________**_*__**___**_**__**___********_**_*_*_**_____________**_______________________*______*____________________****__*______*_******_*__**__*_*_*******__*__**__*____*_______
#=GC scorecons_90         ______*_____*_____________________________________________*__**___**_**__**___*******__**_*_*_*______________**_______________________*___________________________***___*______*_****_*_*__*___*_*__******__*__**__*____________
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