# STOCKHOLM 1.0 #=GF ID 3.20.20.190/FF/000061 #=GF DE Phosphoinositide phospholipase C #=GF AC 3.20.20.190/FF/000061 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 75.760 #=GS Q385H1/242-413_446-575 AC Q385H1 #=GS Q385H1/242-413_446-575 OS Trypanosoma brucei brucei TREU927 #=GS Q385H1/242-413_446-575 DE Phosphoinositide phospholipase C #=GS Q385H1/242-413_446-575 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q385H1/242-413_446-575 DR GO; GO:0004629; GO:0005509; GO:0005737; GO:0006629; GO:0016020; GO:0031982; GO:0035556; GO:0050429; #=GS A9VBY6/403-573_615-753 AC A9VBY6 #=GS A9VBY6/403-573_615-753 OS Monosiga brevicollis #=GS A9VBY6/403-573_615-753 DE Phosphoinositide phospholipase C #=GS A9VBY6/403-573_615-753 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A4I5X4/295-603 AC A4I5X4 #=GS A4I5X4/295-603 OS Leishmania infantum #=GS A4I5X4/295-603 DE Phosphoinositide phospholipase C #=GS A4I5X4/295-603 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A0A1G4HYN3/242-413_446-575 AC A0A1G4HYN3 #=GS A0A1G4HYN3/242-413_446-575 OS Trypanosoma equiperdum #=GS A0A1G4HYN3/242-413_446-575 DE Phosphoinositide phospholipase C #=GS A0A1G4HYN3/242-413_446-575 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS Q4Q6Z7/295-603 AC Q4Q6Z7 #=GS Q4Q6Z7/295-603 OS Leishmania major #=GS Q4Q6Z7/295-603 DE Phosphoinositide phospholipase C #=GS Q4Q6Z7/295-603 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9B168/297-603 AC E9B168 #=GS E9B168/297-603 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9B168/297-603 DE Phosphoinositide phospholipase C #=GS E9B168/297-603 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A3Q8IF05/295-603 AC A0A3Q8IF05 #=GS A0A3Q8IF05/295-603 OS Leishmania donovani #=GS A0A3Q8IF05/295-603 DE Phosphoinositide phospholipase C #=GS A0A3Q8IF05/295-603 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9BM40/295-603 AC E9BM40 #=GS E9BM40/295-603 OS Leishmania donovani BPK282A1 #=GS E9BM40/295-603 DE Phosphoinositide phospholipase C #=GS E9BM40/295-603 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9AEI1/291-598 AC E9AEI1 #=GS E9AEI1/291-598 OS Leishmania major #=GS E9AEI1/291-598 DE Phosphoinositide phospholipase C #=GS E9AEI1/291-598 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS A4IAQ5/291-596 AC A4IAQ5 #=GS A4IAQ5/291-596 OS Leishmania infantum #=GS A4IAQ5/291-596 DE Phosphoinositide phospholipase C #=GS A4IAQ5/291-596 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9BRN6/291-596 AC E9BRN6 #=GS E9BRN6/291-596 OS Leishmania donovani BPK282A1 #=GS E9BRN6/291-596 DE Phosphoinositide phospholipase C #=GS E9BRN6/291-596 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GF SQ 11 Q385H1/242-413_446-575 SSVYHDMTRPICEYFINSSHNTYLTGDQLLSKSSTDMYKRVLLDGCRCVELDCWDGRKGQPVVYHGYTRTSKLWFRDCISTIKKYAFVN-----------SIYPVILSLEVHTSLRQQDRMAEILCETLGDMLFCSPWGAGEQTSFTFSPEALKGKILLKSKRATTPTDGV-QVDDDDD------------------EDEEAVSKVSE-KLSRLISIESIGYKGVEDLSYLEMRQPYHCSSFTEGKAGKIASSNQEE--FVAINNRCLSRIYPTGTRIGSSNFHPQTFWNCGCQLVALNWQNYKSYQLRLNRGFFS-DNGNCGYLLKPTAVDIARA------- A9VBY6/403-573_615-753 SEVYQDMTRPLSQYFIASSHNTYLMEDQLYGSSDVEAYIRALRMGCRCVEIDCWDGEDGEPVVYHGHTLTSKVLLKDVINACAEHGFVT-----------TDFPLILSIENHLSIPQQDKLAEYIKAAFGERLAVVP----FSTEPMPSPASLKGKVIVKGKVNPASASGDGAVSDEDEASEA-----------FEDSKLVSPAFSNIVSLSGVKFKGV-----AQLQQSFTEQKAMQMSSFGEKRAMRLVENEHDTNVFVRRNARQLARTYPAGLRVSSSNYNPQPMWNAGCQIVALNYQTH-TLPMHLNQGRFA-DNGGCGYVLKPEFLRSTETKFNPNDV A4I5X4/295-603 -GVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSQIEMYRRALLAGCRCVELDCWDGKDNDPVIYHGHTRTSKIRFVDVIDTIRRHAFTA-----------SPFPVILSLEVHTSDEQSMVMADHLRTILGDMLMTAK----DIPNMMYTPESLKGKVLVKWKLPHN------DVDDAKEGLAGSDNDSGAARSPSQKAEASSQGALSH-LLRSCVTVGA-----FKTSDWGRDAEPYYIQSYVETVVKELALSHRDE--FIGQTSRMMVRVYPKGTRIGSSNYNPTTAWSVGAQLVALNYQTW-DDDMRLNDGMFS-LNKGCGYVLKPDYLRNPSGKAKAT-- A0A1G4HYN3/242-413_446-575 SSVYHDMTRPICEYFINSSHNTYLTGDQLLSKSSTDMYKRVLLDGCRCVELDCWDGRKGQPVVYHGYTRTSKLWFRDCISTIKKYAFVN-----------SIYPVILSLEVHTSLRQQDRMAEILCETLGDMLFCSPWGAGEQTSFTFSPEALKGKILLKSKRATTPTDGV-QVDDDDD------------------EDEEAVSKVSE-KLSRLISIESIGYKGVEDLSYLEMRQPYHCSSFTEGKAGKIASSNQEE--FVAINNRCLSRIYPTGTRIGSSNFHPQTFWNCGCQLVALNWQNYKSYQLRLNRGFFS-DNGNCGYLLKPTAVDIARA------- Q4Q6Z7/295-603 -GVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSRIEMYRRALLAGCRCVELDCWDGKDNDPVIYHGHTRTSKIRFADVIETIRRHAFTA-----------SPFPVILSLEVHTSDEQSMVMAGHLRTILGDMLMTAK----DIPNMMYTPESLKGKVLVKWKLPHN------DVDDAKEGMTSSDNDNGVARSPSQKAEASAQGALSH-LLRCCVTVGA-----FKTSDWGRDAEPYYIQSYVETVVKELALGHRDE--FIGQTSRMLVRVYPKGTRIGSSNYNPTTAWSVGAQLVALNYQTW-DDDMRLNDGMFS-LNKGCGYVLKPDYLRNPSGKAKAT-- E9B168/297-603 ---VDEMTHPLKDYFINSSHNTYLSGDQFQSSSQIEMYKRALLAGCRCVELDCWDGKDNDPVIYHGHTRTSKIRFADVIDTIRRHAFTT-----------SPFPVILSLEVHTSDEQSMIMADHLRTILGDMLMTAK----DIPDMVYTPESLREKVLVKWKLPYN------DVEDAKEGMADSVNDNDVARSQSQKAEMSAQGGLSH-LLRSCVTVGA-----FKTSDWGRDAEPYYIQSYVETVVKELALSHRAE--FIGQTSRMMVRVYPKGTRIGSSNYNPTTAWSVGAQLVALNYQTW-DDDMRLNDGMFS-LNKGCGYVLKPDYLRNPSGKAKAT-- A0A3Q8IF05/295-603 -GVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSQIEMYRRALLAGCRCVELDCWDGKDNDPVIYHGHTRTSKIRFVDVIDTIRRHAFTA-----------SPFPVILSLEVHTSDEQSMVMADHLRTILGDMLMTAK----DIPNMMYTPESLKGKVLVKWKLPHN------DVDDAKEGLAGSDNDSGAARSPSQKAEASSQGALSH-LLRSCVTVGA-----FKTSDWGRDAEPYYIQSYVETVVKELALSHRDE--FIGQTSRMMVRVYPKGTRIGSSNYNPTTAWSVGAQLVALNYQTW-DDDMRLNDGMFS-LNKGCGYVLKPDYLRNPSGKAKAT-- E9BM40/295-603 -GVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSQIEMYRRALLAGCRCVELDCWDGKDNDPVIYHGHTRTSKIRFVDVIDTIRRHAFTA-----------SPFPVILSLEVHTSDEQSMVMADHLRTILGDMLMTAK----DIPNMMYTPESLKGKVLVKWKLPHN------DVDDAKEGLAGSDNDSGAARSPSQKAEASSQGALSH-LLRSCVTVGA-----FKTSDWGRDAEPYYIQSYVETVVKELALSHRDE--FIGQTSRMMVRVYPKGTRIGSSNYNPTTAWSVGAQLVALNYQTW-DDDMRLNDGMFS-LNKGCGYVLKPDYLRNPSGKAKAT-- E9AEI1/291-598 -RLTDSMDHPLPHYFINSSHNTYLTGNQLNSESSCNMYRDVLLAGCRCVEIDCWDGPAGVPVVYHGHTMTTKIAFDDVVRTINDYAFQNPSNNQEAAWNPRELPVIVSLEVHTSPEQTNRMAEIIRSVFKERLFLSR-----LDASSYTPAKLKGKILVKWKMNAA------GVEDLKDTAGS-----------GIRADRRAPLLTTL-SLSACASIGT-----VRSTSWGAEEQPFHVQSYVEGEVARLEACSPVD--FARQNTHMLSRIYPSGTRIDSSNYDPMLMWRLGCQLVALNWQTR-DHNFRVNEGFFTHQNGGCGYVLKPMYLRDVDAGCSA--- A4IAQ5/291-596 -RLTDSMDHLLPHYFINSSHNTYLTGNQLNSESSCNMYRDVLLAGCRCVEIDCWDGPAGVPVVYHGRTMTTKIAFDDVVRTINDYAFQNPSDNHEAAWNPREFPVIVSLEVHTSPEQTNRMAEIIRSVFKERLFLSR-----LDASSYTPAKLKGKILVKWKMNAA------GVEDLKDTAGS-----------GIRADRRAPLLTTL-KLSACASIGT-----VRSTSWGAEEQPFNVQSYVEGEVARLEACSPVD--FARQNTRMLSRIYPAGTRIDSSNYDPMLMWRLGCQMVALNWQTR-DHNFRVNEGFFTHQNGGCGYVLKPMHLRDVGGGC----- E9BRN6/291-596 -RLTDSMDHLLPHYFINSSHNTYLTGNQLNSESSCNMYRDVLLAGCRCVEIDCWDGPAGVPVVYHGRTMTTKIAFDDVVRTINDYAFQNPSDNHEAAWNPREFPVIVSLEVHTSPEQTNRMAEIIRSVFKERLFLSR-----LDASSYTPAKLKGKILVKWKMNAA------GVEDLKDTAGS-----------GIRADRRAPLLTTL-KLSACASIGT-----VRSTSWGAEEQPFNVQSYVEGEVARLEACSPVD--FARQNTRMLSRIYPAGTRIDSSNYDPMLMWRLGCQMVALNWQTR-DHNFRVNEGFFTHQNGGCGYVLKPMHLRDVGGGC----- #=GC scorecons 0353559666734999799999995769637494457956697599999969999944539979996949696373967377447794500000000000537979697979793594447964654566759435400002344346695498897779494435000000496936732221011000111022356336433453039534455640000045334544445764459759436357535444600954564847496994979859997594549449596999959640534576949495039569997999347644453212100 #=GC scorecons_70 ______*_***__***********_****_*_*___**___**_************____******_*_****_*_*_*_**__***_______________************__*___***_*___*_*_*_______________**__********_*___________*_*__*______________________*________*______*_________________*____**_*__*__*_________*_____*_*_*_**_****_****_*___*__*_******_**______***_*_*___*_********__**___________ #=GC scorecons_80 ______*______***********_*_*__*_*___**___*__******_*****____**_***_*_*_*__*_*_*_**___**________________***_*******__*___**__________*________________*__****_*_*_*___________*_*__________________________________*________________________*____**_*_______________*_____*___*_**_****_****_*___*__*_*_****_*_______*_*_*_*___*__***_***_______________ #=GC scorecons_90 ______*______***_*******___*____*____*___*__******_*****____**_***_*_*_*____*_________*________________*_*_*_*_*_*__*____*__________*________________*__****___*_*___________*_*__________________________________*_____________________________*__*_______________*_________*_**_*_**_***__*___*__*_*_****_*_________*_*_*___*__***_***_______________ //