# STOCKHOLM 1.0 #=GF ID 3.20.20.190/FF/000052 #=GF DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GF AC 3.20.20.190/FF/000052 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 71.262 #=GS G5EBH0/691-885 AC G5EBH0 #=GS G5EBH0/691-885 OS Caenorhabditis elegans #=GS G5EBH0/691-885 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 #=GS G5EBH0/691-885 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS G5EBH0/691-885 DR GO; GO:0005886; GO:0006935; GO:0007212; GO:0014057; GO:0035418; GO:0040012; GO:0040017; GO:0043051; GO:0043052; GO:0046662; GO:0048680; #=GS G5EBH0/691-885 DR EC; 3.1.4.11; #=GS A0A0K3AUN1/557-751 AC A0A0K3AUN1 #=GS A0A0K3AUN1/557-751 OS Caenorhabditis elegans #=GS A0A0K3AUN1/557-751 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3AUN1/557-751 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AS85/557-751 AC A0A0K3AS85 #=GS A0A0K3AS85/557-751 OS Caenorhabditis elegans #=GS A0A0K3AS85/557-751 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3AS85/557-751 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AV83/585-779 AC A0A0K3AV83 #=GS A0A0K3AV83/585-779 OS Caenorhabditis elegans #=GS A0A0K3AV83/585-779 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3AV83/585-779 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AXI3/585-779 AC A0A0K3AXI3 #=GS A0A0K3AXI3/585-779 OS Caenorhabditis elegans #=GS A0A0K3AXI3/585-779 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3AXI3/585-779 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AUM3/663-857 AC A0A0K3AUM3 #=GS A0A0K3AUM3/663-857 OS Caenorhabditis elegans #=GS A0A0K3AUM3/663-857 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3AUM3/663-857 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3ARR7/663-857 AC A0A0K3ARR7 #=GS A0A0K3ARR7/663-857 OS Caenorhabditis elegans #=GS A0A0K3ARR7/663-857 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0K3ARR7/663-857 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS E9HXQ7/638-822 AC E9HXQ7 #=GS E9HXQ7/638-822 OS Daphnia pulex #=GS E9HXQ7/638-822 DE Phosphoinositide phospholipase C #=GS E9HXQ7/638-822 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS E7F5Y6/5-63_124-275 AC E7F5Y6 #=GS E7F5Y6/5-63_124-275 OS Danio rerio #=GS E7F5Y6/5-63_124-275 DE Phosphoinositide phospholipase C #=GS E7F5Y6/5-63_124-275 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS G0PFQ8/693-887 AC G0PFQ8 #=GS G0PFQ8/693-887 OS Caenorhabditis brenneri #=GS G0PFQ8/693-887 DE Phosphoinositide phospholipase C #=GS G0PFQ8/693-887 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; #=GS A0A261BKU6/692-883 AC A0A261BKU6 #=GS A0A261BKU6/692-883 OS Caenorhabditis latens #=GS A0A261BKU6/692-883 DE Phosphoinositide phospholipase C #=GS A0A261BKU6/692-883 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; #=GS E3LKR0/696-887 AC E3LKR0 #=GS E3LKR0/696-887 OS Caenorhabditis remanei #=GS E3LKR0/696-887 DE Phosphoinositide phospholipase C #=GS E3LKR0/696-887 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; #=GS A0A2G5TDC2/688-887 AC A0A2G5TDC2 #=GS A0A2G5TDC2/688-887 OS Caenorhabditis nigoni #=GS A0A2G5TDC2/688-887 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A2G5TDC2/688-887 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A2H2I319/248-447 AC A0A2H2I319 #=GS A0A2H2I319/248-447 OS Caenorhabditis japonica #=GS A0A2H2I319/248-447 DE Phosphoinositide phospholipase C #=GS A0A2H2I319/248-447 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis japonica; #=GS A0A2G5TD79/699-898 AC A0A2G5TD79 #=GS A0A2G5TD79/699-898 OS Caenorhabditis nigoni #=GS A0A2G5TD79/699-898 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A2G5TD79/699-898 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GF SQ 15 G5EBH0/691-885 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3AUN1/557-751 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3AS85/557-751 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3AV83/585-779 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3AXI3/585-779 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3AUM3/663-857 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A0K3ARR7/663-857 ------------------------------PSKHILGGEMP-AKENDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE E9HXQ7/638-822 --------------------------------------KLASETEKIELGVES-RENALNWANAISGCEMEPPFDEQENNDTI--QFSEVENKYSIAKGLSDIIVYCQATHFNQERILSKGRNPCEMSSFCEPEKL-MTQQEYQFFLWYHQVMLSRIYPAGKRIDSSNYNPVPFWNVGSQLVALNYQTPDRSMQLNEARFLQNGKCGYVLKPSYLREYSSDYKPSSV E7F5Y6/5-63_124-275 FVCFRVKQQEKMANYCRTIFGDALLIDLLDKYPLKPGQPIPSPS-------EL-MGKILIKN--------KKSSAEQDEEKMKNSDEGTAGQEVTAYEEMSALVNYVQPNKFISFENAAKKNRCFVISSFVETKGESLIAKNAVDWVEYNKRQLSRIYPKGTRVDSSNYSPQPFWSAGCQFVALNYQTMDFPMQLNMALFEFNGRTGYLLKHDVMRRSDKKFDPFCD G0PFQ8/693-887 -------------------------------SKPNPGGEMP-AKETDEAHPELAKQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEVNNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQPSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A261BKU6/692-883 ---------------------------------PNQGGEIP-VKETDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQPSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE E3LKR0/696-887 ---------------------------------PNQGGEIP-VKETDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQPSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A2G5TDC2/688-887 -----------TSS--------------AGVSKPNQGGEMP-VKETDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQPSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A2H2I319/248-447 ----------STSS----------------QKAGTPAGELPSAKETDEAHPEL-KQNFIAKNLKGFGFSKKQPILTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE A0A2G5TD79/699-898 -----------TSS--------------AGVSKPNQGGEMP-VKETDEAHPEL-KQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQPSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSE #=GC scorecons 00000000000000000000000000000012222243456134523533396055646456333353336564456766545335443564445654379577694664694455564456346479994954653455755446749675649999969597999974954996696959599799694499995549559955997996657964654769665 #=GC scorecons_70 ________________________________________*__________*____*_*__*________*_*___****__________*____*___**_**_*_**_**_____*___*__*_****_*__*_____*____**_***___*******_*******_*__*******_*_*****_*__****___*__**__*******_***_*__***_*_ #=GC scorecons_80 ___________________________________________________*_________________________*_____________________**__*_*_____*______________****_*________________*_____*****_*_*******_*__**__*_*_*_*****_*__****___*__**__**_**___**_____*_*___ #=GC scorecons_90 ___________________________________________________*________________________________________________*____*_____*_______________***_*________________*_____*****_*_*_****__*__**__*_*_*_**_**_*__****___*__**__**_**____*_______*___ //