# STOCKHOLM 1.0
#=GF ID 3.20.20.190/FF/000047
#=GF DE Phosphoinositide phospholipase C
#=GF AC 3.20.20.190/FF/000047
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 67.267
#=GS G5EBH0/337-587      AC G5EBH0
#=GS G5EBH0/337-587      OS Caenorhabditis elegans
#=GS G5EBH0/337-587      DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8
#=GS G5EBH0/337-587      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS G5EBH0/337-587      DR GO; GO:0005886; GO:0006935; GO:0007212; GO:0014057; GO:0035418; GO:0040012; GO:0040017; GO:0043051; GO:0043052; GO:0046662; GO:0048680; 
#=GS G5EBH0/337-587      DR EC; 3.1.4.11; 
#=GS A4IGD0/315-557      AC A4IGD0
#=GS A4IGD0/315-557      OS Danio rerio
#=GS A4IGD0/315-557      DE Phosphoinositide phospholipase C
#=GS A4IGD0/315-557      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; 
#=GS A4IGD0/315-557      DR GO; GO:0043116; GO:0048703; GO:0060536; GO:0090281; 
#=GS A0A0K3AXJ0/309-559  AC A0A0K3AXJ0
#=GS A0A0K3AXJ0/309-559  OS Caenorhabditis elegans
#=GS A0A0K3AXJ0/309-559  DE Phosphoinositide phospholipase C
#=GS A0A0K3AXJ0/309-559  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A0K3AS71/337-587  AC A0A0K3AS71
#=GS A0A0K3AS71/337-587  OS Caenorhabditis elegans
#=GS A0A0K3AS71/337-587  DE Phosphoinositide phospholipase C
#=GS A0A0K3AS71/337-587  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A0K3AS80/309-559  AC A0A0K3AS80
#=GS A0A0K3AS80/309-559  OS Caenorhabditis elegans
#=GS A0A0K3AS80/309-559  DE Phosphoinositide phospholipase C
#=GS A0A0K3AS80/309-559  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A0K3AXH8/337-587  AC A0A0K3AXH8
#=GS A0A0K3AXH8/337-587  OS Caenorhabditis elegans
#=GS A0A0K3AXH8/337-587  DE Phosphoinositide phospholipase C
#=GS A0A0K3AXH8/337-587  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A0K3AUM3/309-560  AC A0A0K3AUM3
#=GS A0A0K3AUM3/309-560  OS Caenorhabditis elegans
#=GS A0A0K3AUM3/309-560  DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
#=GS A0A0K3AUM3/309-560  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A0K3ARR7/309-560  AC A0A0K3ARR7
#=GS A0A0K3ARR7/309-560  OS Caenorhabditis elegans
#=GS A0A0K3ARR7/309-560  DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
#=GS A0A0K3ARR7/309-560  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS T1FQR0/361-627      AC T1FQR0
#=GS T1FQR0/361-627      OS Helobdella robusta
#=GS T1FQR0/361-627      DE Phosphoinositide phospholipase C
#=GS T1FQR0/361-627      DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; 
#=GS G0PFQ8/337-591      AC G0PFQ8
#=GS G0PFQ8/337-591      OS Caenorhabditis brenneri
#=GS G0PFQ8/337-591      DE Phosphoinositide phospholipase C
#=GS G0PFQ8/337-591      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; 
#=GS A0A2G5TDR9/337-590  AC A0A2G5TDR9
#=GS A0A2G5TDR9/337-590  OS Caenorhabditis nigoni
#=GS A0A2G5TDR9/337-590  DE Phosphoinositide phospholipase C
#=GS A0A2G5TDR9/337-590  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A261BKU6/334-588  AC A0A261BKU6
#=GS A0A261BKU6/334-588  OS Caenorhabditis latens
#=GS A0A261BKU6/334-588  DE Phosphoinositide phospholipase C
#=GS A0A261BKU6/334-588  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; 
#=GS E3LKR0/337-591      AC E3LKR0
#=GS E3LKR0/337-591      OS Caenorhabditis remanei
#=GS E3LKR0/337-591      DE Phosphoinositide phospholipase C
#=GS E3LKR0/337-591      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; 
#=GS A8X232/337-597      AC A8X232
#=GS A8X232/337-597      OS Caenorhabditis briggsae
#=GS A8X232/337-597      DE Phosphoinositide phospholipase C
#=GS A8X232/337-597      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS A0A2G5TDC2/337-590  AC A0A2G5TDC2
#=GS A0A2G5TDC2/337-590  OS Caenorhabditis nigoni
#=GS A0A2G5TDC2/337-590  DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
#=GS A0A2G5TDC2/337-590  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A2G5TD79/337-598  AC A0A2G5TD79
#=GS A0A2G5TD79/337-598  OS Caenorhabditis nigoni
#=GS A0A2G5TD79/337-598  DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
#=GS A0A2G5TD79/337-598  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A261BJ96/334-588  AC A0A261BJ96
#=GS A0A261BJ96/334-588  OS Caenorhabditis latens
#=GS A0A261BJ96/334-588  DE Phosphoinositide phospholipase C
#=GS A0A261BJ96/334-588  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; 
#=GS A0A261BJ49/334-588  AC A0A261BJ49
#=GS A0A261BJ49/334-588  OS Caenorhabditis latens
#=GS A0A261BJ49/334-588  DE Phosphoinositide phospholipase C
#=GS A0A261BJ49/334-588  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; 
#=GF SQ 18
G5EBH0/337-587              -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSL---
A4IGD0/315-557              -DIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCRCIELDCWKGRPPEE-EPTITHGFTMTTEIPFK-------DVIEAIAESAFKTSPYPLILSFENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHR--ASNGGSIRRKDGTDEQSSPLNDCPL---SDGDVGQ------------LMSNGGEKLAERMAKDHDNSKSIDRGDGESDEEEEEE-PIPDPKKKKKKKK---------
A0A0K3AXJ0/309-559          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSL---
A0A0K3AS71/337-587          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSL---
A0A0K3AS80/309-559          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSL---
A0A0K3AXH8/337-587          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSL---
A0A0K3AUM3/309-560          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSLD--
A0A0K3ARR7/309-560          -EMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVVLSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAPEEV--DDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSLD--
T1FQR0/361-627              ASINHDMNQPLSHYYISSSHNTYLTGHQLTSRSSVEMYRQVLLSGCRCVELDCWDGRGVDD-EPVITHGFTMCTEVLLK-------DVLEAIMEVAFKTCDYPVLLSFENHC-SPKQQAKMAQHCRTIFGDCLIQEPLPNNPLEPSVPLPSPEALKRKILIKNKKRHSNRSSKKSHSDGLLQQQQQQQQQQQQDLVQKLVEPHLSSERPLLLRHHPPI-QHRQSQPQLPQQS--KLHQLQQQLSHHQFTLQHQQETSPTIPFANQSNSSAELLTPLSPA
G0PFQ8/337-591              -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDVPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVIGEDSVSPR------------SGGSGGTNAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPTVSTTSNNGSNRSARSSLD-T
A0A2G5TDR9/337-590          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLMQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETADVVGEDSVSPR------------SGGSGGTVAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPIVSTTSNNGSNRSARSSLD--
A0A261BKU6/334-588          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPTVSTTSNNGSNRSARSSLE-T
E3LKR0/337-591              -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPTVSTTSNNGSNRSARSSLE-T
A8X232/337-597              -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKCKTPKFQDVLMQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETADVVGEDSVSPR------------SGGSGGTVAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPIVSTTSNNGSNRSARSSLD--
A0A2G5TDC2/337-590          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLMQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETADVVGEDSVSPR------------SGGSGGTVAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPIVSTTSNNGSNRSARSSLD--
A0A2G5TD79/337-598          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLMQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETADVVGEDSVSPRESLFLL-FDLIGSGGSGGTVAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPIVSTTSNNGSNRSARS-----
A0A261BJ96/334-588          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPTVSTTSNNGSNRSARSSLE-T
A0A261BJ49/334-588          -EMYMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFK-------DVLVQIRDTAFARSDFPVILSFENHC-SKSNQLKMAKYCMDIFGDMLLSKPFDDAPLEPGVSLPSPNRLRKKILIKNKRLKTDI--ERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPR------------SGGSGGTGAAEDVAMDDDTSDDDDDPSVQTSLNVMRTVPTVSTTSNNGSNRSARSSLE-T
#=GC scorecons              056449969996997979999999965955759959699999979999799999695645539969999469697757900000009974594759955767976999999609455959995795579994974596554995976599995495599999997465540055554644666654565556674543436654655000000000000445576535674521646565545445447445445639654455555655333434100
#=GC scorecons_70           __*__******_**************_*__*_**_*********************_*____**_****_******_**_______***__*_*_**__*****_*******_*___*_***_**__****_**__**___**_**__****__*__********____________*_____*___*___***______**__*__________________**____*____*_*_*_________*______*_*_________*___________
#=GC scorecons_80           _____**_***_****_********__*____**_*_******_**********_*______**_****__*_*_*_**_______***__*___**____***_******__*___*_***_**__****_**__*____**_*___****__*__*******_________________________________________________________________*___________________________*_____________________
#=GC scorecons_90           _____**_***_**_*_********__*____**_*_******_****_*****_*______**_****__*_*____*_______**___*___**_____*__******__*___*_***__*___***_*___*____**_*___****__*__*******_____________________________________________________________________________________________*_____________________
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