# STOCKHOLM 1.0 #=GF ID 3.20.20.190/FF/000046 #=GF DE Phosphoinositide phospholipase C #=GF AC 3.20.20.190/FF/000046 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 90.265 #=GS Q02158/318-469_501-664 AC Q02158 #=GS Q02158/318-469_501-664 OS Dictyostelium discoideum #=GS Q02158/318-469_501-664 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS Q02158/318-469_501-664 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q02158/318-469_501-664 DR GO; GO:0004435; GO:0016020; GO:0030587; GO:0032959; GO:0045184; GO:0050764; GO:0050922; #=GS Q02158/318-469_501-664 DR EC; 3.1.4.11; #=GS Q8IA75/362-681 AC Q8IA75 #=GS Q8IA75/362-681 OS Caenorhabditis elegans #=GS Q8IA75/362-681 DE Phosphoinositide phospholipase C #=GS Q8IA75/362-681 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q8IA76/355-674 AC Q8IA76 #=GS Q8IA76/355-674 OS Caenorhabditis elegans #=GS Q8IA76/355-674 DE Phosphoinositide phospholipase C #=GS Q8IA76/355-674 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS E9G040/299-611 AC E9G040 #=GS E9G040/299-611 OS Daphnia pulex #=GS E9G040/299-611 DE Phosphoinositide phospholipase C #=GS E9G040/299-611 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS C3Z9I4/302-604 AC C3Z9I4 #=GS C3Z9I4/302-604 OS Branchiostoma floridae #=GS C3Z9I4/302-604 DE Phosphoinositide phospholipase C #=GS C3Z9I4/302-604 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS A0A3Q7XY95/431-747 AC A0A3Q7XY95 #=GS A0A3Q7XY95/431-747 OS Ursus arctos horribilis #=GS A0A3Q7XY95/431-747 DE Phosphoinositide phospholipase C #=GS A0A3Q7XY95/431-747 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus arctos; Ursus arctos horribilis; #=GS F0Z941/318-469_530-685 AC F0Z941 #=GS F0Z941/318-469_530-685 OS Dictyostelium purpureum #=GS F0Z941/318-469_530-685 DE Phosphoinositide phospholipase C #=GS F0Z941/318-469_530-685 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS H3ELI4/288-599 AC H3ELI4 #=GS H3ELI4/288-599 OS Pristionchus pacificus #=GS H3ELI4/288-599 DE Phosphoinositide phospholipase C #=GS H3ELI4/288-599 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS E2RSF7/330-647 AC E2RSF7 #=GS E2RSF7/330-647 OS Canis lupus familiaris #=GS E2RSF7/330-647 DE Phosphoinositide phospholipase C #=GS E2RSF7/330-647 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis; Canis lupus; Canis lupus familiaris; #=GS A8XMK5/354-673 AC A8XMK5 #=GS A8XMK5/354-673 OS Caenorhabditis briggsae #=GS A8XMK5/354-673 DE Phosphoinositide phospholipase C #=GS A8XMK5/354-673 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS A0A1I7UJY8/339-660 AC A0A1I7UJY8 #=GS A0A1I7UJY8/339-660 OS Caenorhabditis tropicalis #=GS A0A1I7UJY8/339-660 DE Phosphoinositide phospholipase C #=GS A0A1I7UJY8/339-660 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis tropicalis; #=GS A0A2G5UPB0/366-685 AC A0A2G5UPB0 #=GS A0A2G5UPB0/366-685 OS Caenorhabditis nigoni #=GS A0A2G5UPB0/366-685 DE Phosphoinositide phospholipase C #=GS A0A2G5UPB0/366-685 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS E3MSL1/356-675 AC E3MSL1 #=GS E3MSL1/356-675 OS Caenorhabditis remanei #=GS E3MSL1/356-675 DE Phosphoinositide phospholipase C #=GS E3MSL1/356-675 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; #=GS A0A0P5ZMD0/422-734 AC A0A0P5ZMD0 #=GS A0A0P5ZMD0/422-734 OS Daphnia magna #=GS A0A0P5ZMD0/422-734 DE Phosphoinositide phospholipase C #=GS A0A0P5ZMD0/422-734 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS A0A2A6BBV6/339-653 AC A0A2A6BBV6 #=GS A0A2A6BBV6/339-653 OS Pristionchus pacificus #=GS A0A2A6BBV6/339-653 DE Phosphoinositide phospholipase C #=GS A0A2A6BBV6/339-653 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A0A2G5UNX7/354-673 AC A0A2G5UNX7 #=GS A0A2G5UNX7/354-673 OS Caenorhabditis nigoni #=GS A0A2G5UNX7/354-673 DE Phosphoinositide phospholipase C #=GS A0A2G5UNX7/354-673 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A1I7UJY7/339-674 AC A0A1I7UJY7 #=GS A0A1I7UJY7/339-674 OS Caenorhabditis tropicalis #=GS A0A1I7UJY7/339-674 DE Phosphoinositide phospholipase C #=GS A0A1I7UJY7/339-674 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis tropicalis; #=GS A0A0P5WUG8/422-734 AC A0A0P5WUG8 #=GS A0A0P5WUG8/422-734 OS Daphnia magna #=GS A0A0P5WUG8/422-734 DE Phosphoinositide phospholipase C #=GS A0A0P5WUG8/422-734 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GF SQ 18 Q02158/318-469_501-664 STVYQDTSKPLSYYFINSSHNTYLSGHQLKGLSTSEMYTNTLRQGCKCVELDVWDGND----GDPIIFHGNTLTSQIKFSHVCETIKARGFETSPYPVILSLEVHCSVPQQIMMANHMKEIFGEMLPTPL-----PEGTKELPTLDSLKYKILLKGHTSHTEYDE----VDDRSASSSSSSFSLSFGSSGKKKKIT--KIKIAPEFEELI------YLVSHGFKSGNTTKE--------------IPS-YKI-HSLVEEKVKQLVQSEPREVVEASQNHLLRVYPRGTR-FDSSNFDPMPGWSIGCQLAALNQQTSSEPMWINDGMFSDNGGCGYVLKPPCLLPGECETYDPTS Q8IA75/362-681 -VVTMDMKQPFSRYFISSSRKSYLVEDQL-GPSSSDGFSSALKRNCRFLEFDIWDPNEADGDTEPMVQNGQTATSKITISSALRIIREFAFERSRYPLLLKVSVHCSTDWQKVAAMLIVTHLGTRLYLPKNDPTNWDDEKNCPTPWDFQNRILIVGKKLDNP-DTDSGEVSEEDDSLASTT----------RRKSK--RIQLCKELSDLVPVFFNVKTLNDLLSTAPGSTT--------------MSSRKNL-ASVTESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD Q8IA76/355-674 -VVTMDMKQPFSRYFISSSRKSYLVEDQL-GPSSSDGFSSALKRNCRFLEFDIWDPNEADGDTEPMVQNGQTATSKITISSALRIIREFAFERSRYPLLLKVSVHCSTDWQKVAAMLIVTHLGTRLYLPKNDPTNWDDEKNCPTPWDFQNRILIVGKKLDNP-DTDSGEVSEEDDSLASTT----------RRKSK--RIQLCKELSDLVPVFFNVKTLNDLLSTAPGSTT--------------MSSRKNL-ASVTESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD E9G040/299-611 MHVHQDMSLPMCHYFISSSHNTYLLEDQLRGPSSVEGYARALQSGCRCIKIDVWD-----GPETPIVYHGNTLTTKIAFSDVVSVIAQFAFEASKYPLFVHLENHCSILQQKTAARIITELFGSALLRAC------DKPLTSTSPEDLVGKIIIFGKKFGSDQMEDGGEVTDEDEGAETNRTRA--GRV--GQASR--RLRICRELSDLI-----ALNRGSSIK-LPSSRD--------------KSKKKKCGYSLSESAASRLHASSPAMWTEMVQRSLLRVFPNGSR-VDSSNFSPLEFWNAGVPMVALNFQTPGLMMDLYDGKFRQNGGCGYVLKPAMMRQPG---FSVPS C3Z9I4/302-604 -KIHQDMTHPLSHYYVFSSHDSYLLPGVE-YVPSLNAYARLLQRGCRYVELVCWDGEH--GDDEPLVCHHPSETTRLRFRSVVEIIAQYAFQASDYPLIIGIDNHCCEEQQIKIVNYIAATFGDMLVRSIV----EEGGVQLPSPYDLKKK--------SSSSLSSTNDMQNALSTVKVKREKG--------------RPPLCKELADLI-----VLCKSDKIEDLPTSAS--------------ESCAQYV-CSFSQSGAIRLAVSFPEEFVNYNKKYMSEVHPDSNKDEDAINYNPQDYWNCGCQIVTVNYHMPGLMTDLNDGRFLENGSCGYVLKPSIMRDEI-AYFSANT A0A3Q7XY95/431-747 --VFQDMDQPLPHYFISSSHNTYLTDSQIGGLSSTEAYVRAFAQGCRCVELDCWEGPG----GEPIIYHGHTLTSKILFRDVVQTVRDHAFTLSPYPVILSLENHCGLEQQAVMARHLRTILGDALVTEALG---AQTPEELPSPEQLKGRVLVKGKKLPAARSEDGRILSDQEEEEEEEEEEA--EAA--EQRRR--AKQISPELSALV-----VYCCATRLRTLHPNPV--------------PPQPCQV-SSLNERKAKKLIREAGNSFVRHNARQLTRVYPLGLR-MNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYILKPACLRQPD-TTFDPEC F0Z941/318-469_530-685 NGVYQDTTRPLTHYFINSSHNTYLSGHQLKGLSTSEMYTYQLRQGCKCVELDVWDGND----GDPIIFHGNTLTSQIKFSHVLQTIKSRGFETSPYPVILSLEVHCSIPQQIIMAQHMKDIFGEMLAMPL-----PEGSKEFPSLESMKFKILLKGHISKTD--------EEPDIKSSSSSFSL--GSS--KKKPT--KEKVAPELSSLI------YLVSHSFKSASNTKE--------------LPC-YLM-HSLSEEKVKALVQTDSKEMIMASHEHFFRAYPKGTR-FDSSNFDPSPGWSIGNQMIALNQQTSSEPMWINDGMFTDNGGCGYVLKPPCLLPEGCEGFDPSS H3ELI4/288-599 -VVWQDMKQPMTRYFIAASHRPFLVEEQQ-GAASVDGIIAALKRSSRWIELEIWNPEE--GEEEPRIQRGPTTNNKIGLRCALETIKEYAFERSRYPVFLRLLVHCKKEWQRVTAALLKEKLAKRLYVPADDPTDWSTNK--PTPFDLQMKIIVVSKRLPSTWKTGDGDVSEEDEIPPSA-----------RRIHK--RLDLAAELSALSAPFLVPKACSDLMSTAPNSHY--------------MSPSSHI-PHISESVALRLMHTYPAEFAQTTRDYSVVISPNLSR-LDSSNLNPQEFWNHGCQIVEMNYQTPGLMMDLQEGKFSENGGCGYVLKPEILNDAL---F---- E2RSF7/330-647 -SVFQDMDQPLSHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPG----GEPIIYHGHTLTSKILFRDVVQAVHDHAFTLSPYPVILSLENHCGLEQQAVMARHLRTILGDTLVTQALD---AQNPEELPSPEQLKGRVLVKGKKLPAARSEDGRILSDQEEEEEEEEEEP--EAT--EQRRR--AKQISPELSALA-----VYCCATRLRTLRPTPV--------------PPQPCQV-SSLNERKAKKLIREAGNSFVRHNARQLTRVYPLGLR-MNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYILKPACLRQPD-TTFDPEC A8XMK5/354-673 -VVTMDMKQPFSRYFISSSRKTFLVEDQL-GPSSSDGFSSALKRNCRFLEFDIWDPNENNGELEPMVQNGQTAHSKITISSALRTIREFAFERSRYPLLLKISVHCSTDWQKVAAKLIVTHLGTRLYLPSNDPTDWDDEKNCPTPWDFQNRILIIGKKLEDP-EAESGDVSEEDDSLASTT----------RKKSK--RITLCKEISDLVPVFFNVKTLNDLLSTAPGSTT--------------MSCRKNL-ASVNESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD A0A1I7UJY8/339-660 -VVTMDMKQPFSRYFISSSRRTYLVEDQL-GPTSADGFASALKRNCRFIEFDIWDPNENNGELEPMIQNGQTAHSKIPISNALRVIREYAFERSRYPLLLKVAVHCSTDWQKVAAKLIVTHLGTRLYLPANDPTDWDDEKNCPTPWDFQNRILIIGKKLDDP-EAESGEVSEEDDSLASTT----------RRKSRNFRITLCKELSDLVPVFFNVKTLNDLLSTAPGSTT--------------MSSRKNL-ASVTESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQIVGLNYQTPGLMMDLQEGKFSDNGACGYVLKPQVMKDDM---FVPSD A0A2G5UPB0/366-685 -VVTMDMKQPFSRYFISSSRKTFLVEDQL-GPSSSDGFSSALKRNCRFLEFDIWDPNENNGELEPMVQNGQTAHSKITISSALRTIREFAFERSRYPLLLKISVHCSTDWQKVAAKLIVTHLGTRLYLPSNDPTDWDDEKNCPTPWDFQNRILIIGKKLEDP-EAESGDVSEEDDSLASAT----------RKKSK--RITLCKEISDLVPVFFNVKTLNDLLSTAPGSTT--------------MSCRKNL-ASVSESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD E3MSL1/356-675 -VVTMDMKQPFSRYFISSSRKSYLVEDQL-GPSSADGFSSALKRNCRFLEFDIWDPNENNGELEPMIQNGQTAHSKIPISNALRIIREFAFERSRFPLLLKISIHCSTDWQKVAAKLIVTHLGTRLYLPTSDPTDWDDEKNCPTPWDFQNRILIIGKKLEDP-EAENGDVSEEDDSLASTT----------RRKSR--RITLCKELSDLVPVFFNVKTLNDLLSTAPGSTT--------------MSCRKNM-ASVNESTCLRLMHTYATDFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD A0A0P5ZMD0/422-734 LHVHQDMTAPMCHYFISSSHNTYLLEDQLRGPSSVEGYARALQSGCRCIKIDVWD-----GPEMPIVYHGNTLTSKIAFSDVISVIAQFAFEASKYPLFIHLENHCSISQQKIAARLITELFGQALLKAA------DKPLTLTSPEELIGKIIIFGKKFGSDQLEDGGEVTDEDEGAETNRTRA--GRV--GQASR--RLRICRELSDLI-----ALNRGSSIK-LPSSRD--------------KKVLQQCGYSLSESAASRLHASSPGMWTEMVQRSLLRVFPNGSR-VDSSNFSPLEFWNAGVPMVALNFQTPGLMMDLYDGKFRQNGGCGYVLKPAMMRQPG---FSIPS A0A2A6BBV6/339-653 -VVWQDMKQPMTRYFIAASHRPFLVEEQQ-GAASVDGIIAALKRSSRWIELEIWNPEE--GEEEPRIQRGPTTNNKIGLRCALETIKEYAFERSRYPVFLRLLVHCKKEWQRVTAALLKEKLAKRLYVPADDPTDWSTNK--PTPFDLQMKIIVVSKRLPSTWKTGDGDVSEEDEIPPSA-----------RRIHK--RLDLAAELSALSAPFLVPKACSDLMSTAPNSHY--------------MSPSSHI-PHISESVALRLMHTYPAEFAQTTRDYSVVISPNLSR-LDSSNLNPQEFWNHGCQIVEMNYQTPGLMMDLQEGKFSENGGCGYVLKPEILNDAL---FTPG- A0A2G5UNX7/354-673 -VVTMDMKQPFSRYFISSSRKTFLVEDQL-GPSSSDGFSSALKRNCRFLEFDIWDPNENNGELEPMVQNGQTAHSKITISSALRTIREFAFERSRYPLLLKISVHCSTDWQKVAAKLIVTHLGTRLYLPSNDPTDWDDEKNCPTPWDFQNRILIIGKKLEDP-EAESGDVSEEDDSLASAT----------RKKSK--RITLCKEISDLVPVFFNVKTLNDLLSTAPGSTT--------------MSCRKNL-ASVSESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGYVLKPQVMKDDM---FVPSD A0A1I7UJY7/339-674 -VVTMDMKQPFSRYFISSSRRTYLVEDQL-GPTSADGFASALKRNCRFIEFDIWDPNENNGELEPMIQNGQTAHSKIPISNALRVIREYAFERSRYPLLLKVAVHCSTDWQKVAAKLIVTHLGTRLYLPANDPTDWDDEKNCPTPWDFQNRILIIGKKLDDP-EAESGEVSEEDDSLASTT----------RRKSRNFRITLCKELSDLVPVFFNVKTLNDLLSTAPGSTTSRCPYNKTRLLSISVSSRKNL-ASVTESTCLRLMHTYATEFGQATRNYCVRVFPNPSR-VDSSNLNPQEFWNNGVQIVGLNYQTPGLMMDLQEGKFSDNGACGYVLKPQVMKDDM---FVPSD A0A0P5WUG8/422-734 LHVHQDMTAPMCHYFISSSHNTYLLEDQLRGPSSVEGYARALQSGCRCIKIDVWD-----GPEMPIVYHGNTLTSKIAFSDVISVIAQFAFEASKYPLFIHLENHCSISQQKIAARLITELFGQALLKAA------DKPLTLTSPEELIGKIIIFGKKFGSDQLEDGGEVTDEDEGAETNRTRA--GRG--GQASR--RLRICRELSDLI-----ALNRGSSIK-LPSSRD--------------KKVLQQCGYSLSESAASRLHASSPGMWTEMVQRSLLRVFPNGSR-VDSSNFSPLEFWNAGVPMVALNFQTPGLMMDLYDGKFRQNGGCGYVLKPAMMRQPG---FSIPS #=GC scorecons 038359745955698857965679455750756746564467555785675759733300423595745748456783554654584557964948965646459953449455844634367449335412111254343376735643765536654343123434365656543454301100100004444400643654977595111114333443544554633000000000000003532344037558544369445354554444545446759545804786955956597394767479588775586745969449959998999446454300083533 #=GC scorecons_70 __*__**__*___***_***__**___*__*_**_*_*__**___**__*_*_**_________*_*__*_*__***________*___***_*_***_*____**____*___*__*___**__*________________*_*_____**___**______________*__________________________*_____***_*___________________*_________________________*__*____**_________________**_*___*__****__*_*_**_*_*_*_**_****__***__*_*__**_*******__*_______*____ #=GC scorecons_80 __*__**__*___***_**___**___*__*__*_______*___**__*___*__________*____*_*___**________*___**__*_**_______**____*___*_______*__*________________*_*___________________________________________________________***_*_____________________________________________*__*_____*__________________*_*___*__**_*__*___**_*___*_**_****__*_*__*_*__**_*******__________*____ #=GC scorecons_90 __*__*___*___***__*____*_____________________________*__________*______*____*________*____*__*_**_______**____*___*__________*______________________________________________________________________________*___*________________________________________________*_____*____________________*___*___*_*__*___*__*______*_**____*____*_*__**_*******__________*____ //