# STOCKHOLM 1.0 #=GF ID 2.70.240.20/FF/000001 #=GF DE Heat-labile hemolysin #=GF AC 2.70.240.20/FF/000001 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 22.623 #=GS 1xezA02/111-281_330-586 AC P09545 #=GS 1xezA02/111-281_330-586 OS Vibrio cholerae O1 biovar El Tor str. N16961 #=GS 1xezA02/111-281_330-586 DE Hemolysin #=GS 1xezA02/111-281_330-586 DR CATH; 1xez; A:135-276; A:325-581; #=GS 1xezA02/111-281_330-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS 1xezA02/111-281_330-586 DR GO; GO:0042802; #=GS P09545/165-301_350-586 AC P09545 #=GS P09545/165-301_350-586 OS Vibrio cholerae O1 biovar El Tor str. N16961 #=GS P09545/165-301_350-586 DE Hemolysin #=GS P09545/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS P09545/165-301_350-586 DR GO; GO:0042802; #=GS O06693/168-304_353-589 AC O06693 #=GS O06693/168-304_353-589 OS Vibrio mimicus #=GS O06693/168-304_353-589 DE Heat-labile hemolysin #=GS O06693/168-304_353-589 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio mimicus; #=GS A0A0Q0Q2U0/166-302_351-587 AC A0A0Q0Q2U0 #=GS A0A0Q0Q2U0/166-302_351-587 OS Vibrio metoecus #=GS A0A0Q0Q2U0/166-302_351-587 DE Hemolysin #=GS A0A0Q0Q2U0/166-302_351-587 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio metoecus; #=GS A0A0H6S9Q1/165-301_350-576 AC A0A0H6S9Q1 #=GS A0A0H6S9Q1/165-301_350-576 OS Vibrio cholerae #=GS A0A0H6S9Q1/165-301_350-576 DE Hemolysin #=GS A0A0H6S9Q1/165-301_350-576 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS A0A0K9UXC5/165-301_350-586 AC A0A0K9UXC5 #=GS A0A0K9UXC5/165-301_350-586 OS Vibrio cholerae 2740-80 #=GS A0A0K9UXC5/165-301_350-586 DE Hemolysin #=GS A0A0K9UXC5/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS C3LUN9/165-301_350-586 AC C3LUN9 #=GS C3LUN9/165-301_350-586 OS Vibrio cholerae M66-2 #=GS C3LUN9/165-301_350-586 DE Hemolysin #=GS C3LUN9/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS A0A0U2JMS9/165-301_350-586 AC A0A0U2JMS9 #=GS A0A0U2JMS9/165-301_350-586 OS Vibrio cholerae #=GS A0A0U2JMS9/165-301_350-586 DE HlyA #=GS A0A0U2JMS9/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS A0A0X1L2D5/165-301_350-586 AC A0A0X1L2D5 #=GS A0A0X1L2D5/165-301_350-586 OS Vibrio cholerae MO10 #=GS A0A0X1L2D5/165-301_350-586 DE Hemolysin #=GS A0A0X1L2D5/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS A0A0H6SZL4/165-301_350-586 AC A0A0H6SZL4 #=GS A0A0H6SZL4/165-301_350-586 OS Vibrio cholerae #=GS A0A0H6SZL4/165-301_350-586 DE Hemolysin #=GS A0A0H6SZL4/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS A0A0H3Q3T4/165-301_350-586 AC A0A0H3Q3T4 #=GS A0A0H3Q3T4/165-301_350-586 OS Vibrio cholerae B33 #=GS A0A0H3Q3T4/165-301_350-586 DE Cytolysin and hemolysin HlyA Pore-forming toxin #=GS A0A0H3Q3T4/165-301_350-586 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GS B6EBE2/1-122_171-407 AC B6EBE2 #=GS B6EBE2/1-122_171-407 OS Vibrio mimicus #=GS B6EBE2/1-122_171-407 DE Heat-labile hemolysin #=GS B6EBE2/1-122_171-407 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio mimicus; #=GS A0A0H6ZYY4/2-135_184-413 AC A0A0H6ZYY4 #=GS A0A0H6ZYY4/2-135_184-413 OS Vibrio cholerae #=GS A0A0H6ZYY4/2-135_184-413 DE Hemolysin #=GS A0A0H6ZYY4/2-135_184-413 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; #=GF SQ 13 1xezA02/111-281_330-586 EIDPALLEAPRTAALLGASGFASPAPANSETNTLPHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLTANMCDSQQSAQSFIYDQLGRYVSASNTKLCLDGAALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGLYASSNDAVSLRTITAYTDVF P09545/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- O06693/168-304_353-589 ----------------------------------PHVAFYINVNRSISDEECTFANSWLWKNDKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRFFKAGYTTLDAYFREWSTDAIAQDYRFSFNASNDKAQILKTFPVTNVDYRIERSAKNAQNVSFTWNRQQYATAESLLNRSTDALWVETYPVDVNRISPLSYASFVPKMDVIYKASPKETGSTVFVIDSSVNIRPIYNGAYKHYYVVGSHQSYHGFEDTPRRRVTKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIEADDQGRLMATTCDSQQAAQSFIYDQQGRYVSASNTKLCLDGEALDSLHTCNQNLTQRWEWREGSDRLSNVFNGEVLGHDKQTGELGL-------------------- A0A0Q0Q2U0/166-302_351-587 ----------------------------------PHVAFYINVNRAISDEECTFSNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGADYVTLDAYFREWSTDAIAQDYRFAFNASNSKAQILKTFPVTNVDYRIERNAKNAQNVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASPTETGSTDFVIDSSVNLRPIYNGAYKHYYVFGAHQSYHGFEDTPRRRVTKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIEVGEQGRLTANTCDNQRAAQSFIYDQLGRYVSASNTKLCLDGAGLDSLQACSQNLTQRWEWREGTDELGNVYSGEVLGHDKQTGELGL-------------------- A0A0H6S9Q1/165-301_350-576 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQFYHGFEDTPRRRITKSASFTVDWDHPVFTGGXXXVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGEXX------------------------------- A0A0K9UXC5/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- C3LUN9/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- A0A0U2JMS9/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- A0A0X1L2D5/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQFYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- A0A0H6SZL4/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQFYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- A0A0H3Q3T4/165-301_350-586 ----------------------------------PHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQFYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGL-------------------- B6EBE2/1-122_171-407 -------------------------------------------------EECTFANSWLWKNDKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRFFKAGYTTLDAYFREWSTDAIAQDYRFSFNASNDKAQILKTFPVTNVDYRIERSAKNAQNVSFTWNRQQYATAESLLNRSTDALWVETYPVDVNRISPLSYASFVPKMDVIYKASPKETGSTDFVIDSSVNIRPIYNGAYKHYYVVGSHQSYHGFEDTPRRRVTKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIEADDQGRLMATTCDSQQAAQSFIYDQQGRYVSASNTKLCLDGEALDSLHTCNQNLTQRWEWREGSDELSNVFNGEVLGHDKQTGELGL-------------------- A0A0H6ZYY4/2-135_184-413 -------------------------------------AFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNIDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQFYHGFEDTPRRRITKSASFTVDWDHPVFTGG-RPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDX--------------------------- #=GC scorecons 000000000000000000000000000000000055566665666566699999599999997999999999999999999999999999999999999999999999999999999999999959696979999999999999999999959999969999999999597999999699999699999999999999999999999999699999999999999999999999999996699999797999999899999999999997969959999999999979999999999999999990779999999999999668599994966998986999999996999999999999999689969769899999999996969796997699477776666666600000000000000000000 #=GC scorecons_70 _____________________________________****_***_********_*********************************************************************_***_**********************_****************_**************_******************************************************************************************_******************************_******************_****_*****************_***************_******_******************_******_****____________________________ #=GC scorecons_80 _________________________________________________*****_*********************************************************************_*_*_**********************_*****_**********_********_*****_**************************_****************************__******************************_**_******************************_***************__*_****_*__*****_********_***************_***_**_************_*_***_***_**_****____________________________ #=GC scorecons_90 _________________________________________________*****_*******_*************************************************************_*_*_*_********************_*****_**********_*_******_*****_**************************_****************************__*****_*_********************_*_**_***********_******************___*************____****_*__**_**_********_***************__**_*__*_**********_*_*_*_**__**_________________________________ //