# STOCKHOLM 1.0 #=GF ID 2.60.200.40/FF/000024 #=GF DE Sphingosine kinase A #=GF AC 2.60.200.40/FF/000024 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 79.389 #=GS Q86KF9/306-369_413-432_504-622 AC Q86KF9 #=GS Q86KF9/306-369_413-432_504-622 OS Dictyostelium discoideum #=GS Q86KF9/306-369_413-432_504-622 DE Sphingosine kinase A #=GS Q86KF9/306-369_413-432_504-622 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q86KF9/306-369_413-432_504-622 DR GO; GO:0005524; GO:0005634; GO:0005829; GO:0006648; GO:0017050; GO:0031143; GO:1903666; GO:1904643; #=GS Q86KF9/306-369_413-432_504-622 DR EC; 2.7.1.91; #=GS Q9VZW0/351-438_530-659 AC Q9VZW0 #=GS Q9VZW0/351-438_530-659 OS Drosophila melanogaster #=GS Q9VZW0/351-438_530-659 DE LD11247p #=GS Q9VZW0/351-438_530-659 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VZW0/351-438_530-659 DR GO; GO:0005737; GO:0005765; GO:0006665; GO:0007629; GO:0016310; GO:0017050; GO:0018991; #=GS Q9VYY8/330-411_508-638 AC Q9VYY8 #=GS Q9VYY8/330-411_508-638 OS Drosophila melanogaster #=GS Q9VYY8/330-411_508-638 DE RE64552p #=GS Q9VYY8/330-411_508-638 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VYY8/330-411_508-638 DR GO; GO:0005829; GO:0005886; GO:0006665; GO:0016310; GO:0017050; #=GS Q6B516/437-498_547-580_639-757 AC Q6B516 #=GS Q6B516/437-498_547-580_639-757 OS Dictyostelium discoideum #=GS Q6B516/437-498_547-580_639-757 DE Sphingosine kinase B #=GS Q6B516/437-498_547-580_639-757 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q6B516/437-498_547-580_639-757 DR GO; GO:0005524; GO:0006648; GO:0017050; GO:1903666; #=GS Q6B516/437-498_547-580_639-757 DR EC; 2.7.1.91; #=GS B3NUD3/334-422_516-646 AC B3NUD3 #=GS B3NUD3/334-422_516-646 OS Drosophila erecta #=GS B3NUD3/334-422_516-646 DE Uncharacterized protein #=GS B3NUD3/334-422_516-646 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4PYA8/335-413_508-638 AC B4PYA8 #=GS B4PYA8/335-413_508-638 OS Drosophila yakuba #=GS B4PYA8/335-413_508-638 DE Uncharacterized protein, isoform A #=GS B4PYA8/335-413_508-638 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS B4QP12/351-438_530-659 AC B4QP12 #=GS B4QP12/351-438_530-659 OS Drosophila simulans #=GS B4QP12/351-438_530-659 DE GD13722 #=GS B4QP12/351-438_530-659 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4HTJ0/351-439_506-635 AC B4HTJ0 #=GS B4HTJ0/351-439_506-635 OS Drosophila sechellia #=GS B4HTJ0/351-439_506-635 DE GM14525 #=GS B4HTJ0/351-439_506-635 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B3NF21/376-463_555-684 AC B3NF21 #=GS B3NF21/376-463_555-684 OS Drosophila erecta #=GS B3NF21/376-463_555-684 DE Uncharacterized protein #=GS B3NF21/376-463_555-684 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GF SQ 9 Q86KF9/306-369_413-432_504-622 DVSVIQQGDKK----WCSILSLTWGIVSDVDIESEKYRALGDVRLILGAALRILNLRIYRGKIWYLPATNQLRRSSLNNSSN----------------------GFSPKLAKGWKVLEGEFIGIVASTVSHLASDFIASPTAHLSDGLIDLVVINNNKKFSKAGLLSVLTESSTGAHV---KSDLIDQYKVQAMILEPSNDREGIIAVDGELISYGRTSMECMRACINLICR Q9VZW0/351-438_530-659 -VVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLTDHEVSSTHSATGYAAQRRMQSS----RSC-SELPDLNEPLSEDQGWLVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILI--RAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPY-DNHGIITVDGERVEFGPLQAEVLPGIARVMV- Q9VYY8/330-411_508-638 ----VELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEA---ARELPAES---------GTIPPLQMPLLSSDGWICEDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVII--RRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPS-SSDGILVVDGERVEYGPIQAEVMPGLINVMTT Q6B516/437-498_547-580_639-757 --NNNNSNITK----WCSILSLTWGLVSDVDIESEKYRSLGDLRLIIGAAVRILNLRIYRGKVYFLPAQNEINSTTSNNNNNNNTTTTST--------SSSTSTSTSTSSSKGWKCIEGEFIGVVASTVSHLASDFISSPNAHLSDGLIDLIFINNRSKLSKASLLSILTDSATGDHL---KSDLIEHHKVKALILEPSIQKHGIVAIDGERIPYAKTSMENIRGCLNLICR B3NUD3/334-422_516-646 --------PRDKHFVLYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLVAKGKMEPPVEAAQEAREIPGESDQQKRPSA-GTIPGLQMPLPSSEGWICEDGEFVMVHAGYTTHLSTDVFFAPESRLDDGLIYLVII--RSGVSRHQLLNFMLSLNTGTHLPIGEDPFIKVVPCRAFRIEPS-SSDGILVVDGERVDYGPIQAEVMPGLINVMTT B4PYA8/335-413_508-638 ---------GDKHFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLAKDRKEPPVEAAKEAREIPVE----------GTIPGLQMPLPSSEGWICEDGDFVMVHAAYTTHLSSDVFFAPDSRLNDGLIYLVII--RSGVSRHQLLNFMLSLNTGTHLPIGEDPFIKVVPCRAFRIEPS-STDGILAVDGERVDYGPIQAEVMPGLINVMTT B4QP12/351-438_530-659 -VVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRVLGYQRFTVWTLYRLVNLRTYNGKISYLLTDHEVSSTHSATGYAAQRRMQSS----RSC-SELPDLSEPLSEDQGWLVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILI--RAGISRPHLLSFLYNMSSGTHLPEAHDDHVKVLPVRAFRLEPY-DNHGIITVDGERVEFGPLQAEVLPGIARVMV- B4HTJ0/351-439_506-635 -VVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRVLGYQRFTVWTLYRLVNLRTYNGRISYLLTDHEVSSTHSATGYAAQRRMQSS----RSCNSELPDLSEPLSEEQGWLVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILI--RAGISRPHLLSFLYNMSSGTHLPEAQDDHVKVLPVRAFRLEPY-DNHGIITVDGERVEFGPLQAEVLPGIARVMV- B3NF21/376-463_555-684 -VVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRLLGYQRFTVWTLYRLVNLRTYNGRISYLLTDHQVSATQSASGYAAQRRMQSS----RSC-SELPDLNEPLPEDQGWLVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILI--RAGISRPQLLSFLYNMSSGTHLPEAHNDHVKVLPVRAFRLEPH-DNHGIITVDGERVEFGPLQAEVLPGIARVMV- #=GC scorecons 0211332225400004696995699776979999974946935966556439655994959765895544434453463226332323410000111043342443654444993447979755594536994494456946595995959659007455974499656344559597422455476435569656995044599557999674775455956574556641 #=GC scorecons_70 ________________**_**__****_********_*_**__***__*__**__**_*_***_**________________________________________*_____**___*****___*___***__*___**___*_**_*_**_*__*___**__**__*_____*_**_______*_____**__***_____**__******_**____*___*___**__ #=GC scorecons_80 _________________*_**__****_*_******_*__*__*_______*___**_*_*___**______________________________________________**____****___*____**__*____*___*_**_*_*__*______**__**________*_**______________*___**_____**__****_*_**____*___*_______ #=GC scorecons_90 _________________*_**__**___*_*****__*__*__*_______*___**_*_*___**______________________________________________**____*_*____*____**__*____*___*_**_*_*__*______*___**________*_*_______________*___**_____**___***_________*___________ //