# STOCKHOLM 1.0 #=GF ID 2.40.30.10/FF/000096 #=GF DE tRNA-specific 2-thiouridylase MnmA #=GF AC 2.40.30.10/FF/000096 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 61.102 #=GS O86583/290-373 AC O86583 #=GS O86583/290-373 OS Streptomyces coelicolor A3(2) #=GS O86583/290-373 DE tRNA-specific 2-thiouridylase MnmA #=GS O86583/290-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group; Streptomyces coelicolor; #=GS O86583/290-373 DR EC; 2.8.1.13; #=GS P9WJS5/275-357 AC P9WJS5 #=GS P9WJS5/275-357 OS Mycobacterium tuberculosis H37Rv #=GS P9WJS5/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS P9WJS5/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS P9WJS5/275-357 DR EC; 2.8.1.13; #=GS A0A0N1GV07/291-373 AC A0A0N1GV07 #=GS A0A0N1GV07/291-373 OS Actinobacteria bacterium OV320 #=GS A0A0N1GV07/291-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0N1GV07/291-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Actinobacteria bacterium OV320; #=GS D6ESY3/290-373 AC D6ESY3 #=GS D6ESY3/290-373 OS Streptomyces lividans TK24 #=GS D6ESY3/290-373 DE tRNA-specific 2-thiouridylase MnmA #=GS D6ESY3/290-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces lividans; #=GS D6ESY3/290-373 DR EC; 2.8.1.13; #=GS A0A3S8XMR5/290-373 AC A0A3S8XMR5 #=GS A0A3S8XMR5/290-373 OS Streptomyces sp. KPB2 #=GS A0A3S8XMR5/290-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A3S8XMR5/290-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. KPB2; #=GS A0A0X3XTD9/290-375 AC A0A0X3XTD9 #=GS A0A0X3XTD9/290-375 OS Streptomyces sp. NRRL WC-3605 #=GS A0A0X3XTD9/290-375 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0X3XTD9/290-375 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. NRRL WC-3605; #=GS A0A124GU88/292-374 AC A0A124GU88 #=GS A0A124GU88/292-374 OS Streptomyces curacoi #=GS A0A124GU88/292-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A124GU88/292-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces curacoi; #=GS A0A1V9KFY2/289-371 AC A0A1V9KFY2 #=GS A0A1V9KFY2/289-371 OS Streptomyces sp. M41(2017) #=GS A0A1V9KFY2/289-371 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A1V9KFY2/289-371 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. M41(2017); #=GS A0A101U5Z7/290-374 AC A0A101U5Z7 #=GS A0A101U5Z7/290-374 OS Streptomyces caeruleatus #=GS A0A101U5Z7/290-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A101U5Z7/290-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces caeruleatus; #=GS A0A3R9SVA7/290-373 AC A0A3R9SVA7 #=GS A0A3R9SVA7/290-373 OS Streptomyces sp. WAC08401 #=GS A0A3R9SVA7/290-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A3R9SVA7/290-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. WAC08401; #=GS A0A0M8QKU5/291-374 AC A0A0M8QKU5 #=GS A0A0M8QKU5/291-374 OS Streptomyces caelestis #=GS A0A0M8QKU5/291-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0M8QKU5/291-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces caelestis; #=GS A0A0M2GJX8/291-374 AC A0A0M2GJX8 #=GS A0A0M2GJX8/291-374 OS Streptomyces variegatus #=GS A0A0M2GJX8/291-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0M2GJX8/291-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces variegatus; #=GS G2GBW5/289-373 AC G2GBW5 #=GS G2GBW5/289-373 OS Streptomyces zinciresistens K42 #=GS G2GBW5/289-373 DE tRNA-specific 2-thiouridylase MnmA #=GS G2GBW5/289-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces zinciresistens; #=GS K4R3M2/275-357 AC K4R3M2 #=GS K4R3M2/275-357 OS Streptomyces davaonensis JCM 4913 #=GS K4R3M2/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS K4R3M2/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces davaonensis; #=GS A0A124H8U6/288-371 AC A0A124H8U6 #=GS A0A124H8U6/288-371 OS Streptomyces pseudovenezuelae #=GS A0A124H8U6/288-371 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A124H8U6/288-371 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces pseudovenezuelae; #=GS A0A081XSD4/289-375 AC A0A081XSD4 #=GS A0A081XSD4/289-375 OS Streptomyces toyocaensis #=GS A0A081XSD4/289-375 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A081XSD4/289-375 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces toyocaensis; #=GS A0A2A2YXV8/291-373 AC A0A2A2YXV8 #=GS A0A2A2YXV8/291-373 OS Streptomyces sp. SA15 #=GS A0A2A2YXV8/291-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A2A2YXV8/291-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. SA15; #=GS C9Z5C3/290-374 AC C9Z5C3 #=GS C9Z5C3/290-374 OS Streptomyces scabiei 87.22 #=GS C9Z5C3/290-374 DE tRNA-specific 2-thiouridylase MnmA #=GS C9Z5C3/290-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces scabiei; #=GS A0A0Q8YUI8/292-374 AC A0A0Q8YUI8 #=GS A0A0Q8YUI8/292-374 OS Streptomyces sp. Root264 #=GS A0A0Q8YUI8/292-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0Q8YUI8/292-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. Root264; #=GS A0A1H9X5V5/289-373 AC A0A1H9X5V5 #=GS A0A1H9X5V5/289-373 OS Streptomyces sp. yr375 #=GS A0A1H9X5V5/289-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A1H9X5V5/289-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. yr375; #=GS A0A3Q9ERM9/291-373 AC A0A3Q9ERM9 #=GS A0A3Q9ERM9/291-373 OS Streptomyces sp. MK-45 #=GS A0A3Q9ERM9/291-373 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A3Q9ERM9/291-373 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. MK-45; #=GS L7F626/288-371 AC L7F626 #=GS L7F626/288-371 OS Streptomyces turgidiscabies Car8 #=GS L7F626/288-371 DE tRNA-specific 2-thiouridylase MnmA #=GS L7F626/288-371 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces turgidiscabies; #=GS A0A1D8SV18/291-374 AC A0A1D8SV18 #=GS A0A1D8SV18/291-374 OS Streptomyces olivaceus #=GS A0A1D8SV18/291-374 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A1D8SV18/291-374 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces olivaceus; #=GS P66977/275-357 AC P66977 #=GS P66977/275-357 OS Mycobacterium tuberculosis variant bovis AF2122/97 #=GS P66977/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS P66977/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS P66977/275-357 DR EC; 2.8.1.13; #=GS A1KN20/275-357 AC A1KN20 #=GS A1KN20/275-357 OS Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 #=GS A1KN20/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS A1KN20/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A1KN20/275-357 DR EC; 2.8.1.13; #=GS C1AGE1/275-357 AC C1AGE1 #=GS C1AGE1/275-357 OS Mycobacterium tuberculosis variant bovis BCG str. Tokyo 172 #=GS C1AGE1/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS C1AGE1/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS C1AGE1/275-357 DR EC; 2.8.1.13; #=GS A5U737/275-357 AC A5U737 #=GS A5U737/275-357 OS Mycobacterium tuberculosis H37Ra #=GS A5U737/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS A5U737/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A5U737/275-357 DR EC; 2.8.1.13; #=GS P9WJS4/275-357 AC P9WJS4 #=GS P9WJS4/275-357 OS Mycobacterium tuberculosis CDC1551 #=GS P9WJS4/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS P9WJS4/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS P9WJS4/275-357 DR EC; 2.8.1.13; #=GS A0A045JAW2/275-357 AC A0A045JAW2 #=GS A0A045JAW2/275-357 OS Mycobacterium tuberculosis #=GS A0A045JAW2/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A045JAW2/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A045JAW2/275-357 DR EC; 2.8.1.13; #=GS A0A328G9D1/275-357 AC A0A328G9D1 #=GS A0A328G9D1/275-357 OS Mycobacterium tuberculosis variant pinnipedii #=GS A0A328G9D1/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A328G9D1/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A328G9D1/275-357 DR EC; 2.8.1.13; #=GS A0A0H3LHP3/275-357 AC A0A0H3LHP3 #=GS A0A0H3LHP3/275-357 OS Mycobacterium tuberculosis str. Erdman = ATCC 35801 #=GS A0A0H3LHP3/275-357 DE tRNA-specific 2-thiouridylase MnmA #=GS A0A0H3LHP3/275-357 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A0H3LHP3/275-357 DR EC; 2.8.1.13; #=GS A0A0T7PJ61/161-243 AC A0A0T7PJ61 #=GS A0A0T7PJ61/161-243 OS Mycobacterium tuberculosis #=GS A0A0T7PJ61/161-243 DE tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TRMU #=GS A0A0T7PJ61/161-243 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GF SQ 32 O86583/290-373 -DVDALRAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVRAELVDGTLEVTFSEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRATA-- P9WJS5/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A0A0N1GV07/291-373 --VAALTAIRPRW-CGAAPTGPGTYTAQLRAHGGETEVRAELVDGSLEVTFTEPVRGVAPGQAIVLYD----DTRVVGSATIAATVRATA-- D6ESY3/290-373 -DVDALRAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVRAELVDGTLEVTFSEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRATA-- A0A3S8XMR5/290-373 -DVDALTAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVRAEPVDGTLEVTFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRATA-- A0A0X3XTD9/290-375 -DVSALTAIKPRW-CGAAPSGPGTYTAQLRAHGGETEVTAELVDGSLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRVKEAT A0A124GU88/292-374 ---GALTAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVTAELVDGSLEVTFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRATAG- A0A1V9KFY2/289-371 --VSALTALKPRW-CGAAPTGPGTYTAQLRAHGGETEVAAELVDGSLRVTFTEPVRGVAPGQAIVLYD----GTRVVGSATIATTTRATA-- A0A101U5Z7/290-374 -DVSALTAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVSAELVDGSLEVTFTEPVRGVAPGQAVVLYD----GTRVVGSATIASTVRATPT- A0A3R9SVA7/290-373 -DVDALRAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVSAELVDGVLEVSFAEPVRGVAPGQAIVLYD----GTRVVGSATIASTSRATA-- A0A0M8QKU5/291-374 --VTALTAIRPRW-CGAAPTGPGAYTAQLRAHGGETEVRAELVDGTLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRATAG- A0A0M2GJX8/291-374 --VSALTAVKPRW-CGAAPTGPGSYTAQLRAHGGETEVTAEVVDGSLEVVFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRATAG- G2GBW5/289-373 LDVTALSAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVHAELLDGALEVTFAEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRATP-- K4R3M2/275-357 --VTALRAIKPRW-CGTAPTGPGTYTAQLRAHGGETEVTAELVDGTLEVTFTEPVRGVAPGQAIVLYD----DTRVVGSATISTTTRATA-- A0A124H8U6/288-371 -DVTALSAIKPRW-CGTAPVGPGTYTAQLRAHGGETEVTAELVDGALEVSFTEPVRGVAPGQAIVLYD----DTRVVGSATIASTVRVRA-- A0A081XSD4/289-375 LDVSALSAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVTAELVDGTLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRAGQTA A0A2A2YXV8/291-373 --VSALTAVKPRW-CGAAPTGPGTYTAQLRAHGGETEVTAELVDGDLQVRFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTRRATA-- C9Z5C3/290-374 -DVEALTAIRPRW-CGAAPTGPGTYTAQLRAHGGETEVRAEPVDGTLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRAGAA- A0A0Q8YUI8/292-374 ---GALTAIKPRW-CGAAPTGPGVYTAQLRAHGGETEVAAELVDGRLEVTFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRTTAG- A0A1H9X5V5/289-373 -DVTALTAIKPRW-CGAAPTGPGTYTAQLRAHGGETEVTAELLDGRLEVAFTEPVRGVAPGQAIVLYD----DTRVVGSATIASTVRATAG- A0A3Q9ERM9/291-373 --VTALTAVKPRW-CGVAPTGPGTYTAQLRAHGGETEVTAELVDGSLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTVRATP-- L7F626/288-371 -DVDALTAIRPRW-CGAAPTGPGTYTAQLRAHGGETEVTAELVDGTLEVTFTEPVRGVAPGQAIVLYD----GTRVVGSATIATTNRAAA-- A0A1D8SV18/291-374 --VDALRAIKPRW-CGAAPAGPGTYTAQLRAHGGETEVRAQLVDGTLEVSFTEPVRGVAPGQAIVLYD----GTRVVGSATIASTTRATAD- P66977/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A1KN20/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ C1AGE1/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A5U737/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ P9WJS4/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A0A045JAW2/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A0A328G9D1/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A0A0H3LHP3/275-357 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ A0A0T7PJ61/161-243 ---QTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGAS------ #=GC scorecons 00246966459551598995995565696999965556498866659494655969999599669995111175596999998564322200 #=GC scorecons_70 ____***___*____****_**__*__******______****___*_*_*__******_*******_____*__********_*_______ #=GC scorecons_80 _____*____*____****_**_____*_****______***____*_*____*_****_**__***_____*__*_******_________ #=GC scorecons_90 _____*____*____****_**_____*_****______***____*_*____*_****_**__***________*_******_________ //