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CATH Superfamily 2.40.128.480

Rhodococcus equi virulence-associated protein

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhodococcus equi virulence-associated protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Rhodococcus equi virulence-associated protein

Rhodococcus equi is a multi-host pathogen that infects a range of animals and immune-compromised humans. Equine and porcine isolates harbour a virulence plasmid encoding a homologous family of virulence-associated proteins that allow the diversion of the normal processes of endosomal maturation to enable bacterial survival and proliferation in alveolar macrophagesPMID:25005079,PMID:25746683,PMID:25084333. Functional characterisation of members of this superfamily is still in the process of being elucidated.

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
86 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO:
Taxonomy
Unique Species: 86
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