# STOCKHOLM 1.0 #=GF ID 2.40.10.10/FF/000146 #=GF DE Serine protease 53 #=GF AC 2.40.10.10/FF/000146 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 94.882 #=GS A1ZAT2/29-266 AC A1ZAT2 #=GS A1ZAT2/29-266 OS Drosophila melanogaster #=GS A1ZAT2/29-266 DE Uncharacterized protein #=GS A1ZAT2/29-266 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A1ZAT2/29-266 DR GO; GO:0004252; GO:0006508; GO:0035207; #=GS Q9Y122/193-439 AC Q9Y122 #=GS Q9Y122/193-439 OS Drosophila melanogaster #=GS Q9Y122/193-439 DE BcDNA.GH08420 #=GS Q9Y122/193-439 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9Y122/193-439 DR GO; GO:0004175; GO:0004252; GO:0006508; #=GS Q4V653/29-260 AC Q4V653 #=GS Q4V653/29-260 OS Drosophila melanogaster #=GS Q4V653/29-260 DE IP05687p #=GS Q4V653/29-260 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q4V653/29-260 DR GO; GO:0004252; GO:0050830; #=GS Q8MR00/30-267 AC Q8MR00 #=GS Q8MR00/30-267 OS Drosophila melanogaster #=GS Q8MR00/30-267 DE LP05421p #=GS Q8MR00/30-267 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q8MR00/30-267 DR GO; GO:0004252; GO:0006508; GO:0035207; #=GS B7ZWH8/40-273 AC B7ZWH8 #=GS B7ZWH8/40-273 OS Mus musculus #=GS B7ZWH8/40-273 DE BC039632 protein #=GS B7ZWH8/40-273 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q9VXC7/21-260 AC Q9VXC7 #=GS Q9VXC7/21-260 OS Drosophila melanogaster #=GS Q9VXC7/21-260 DE RE37738p #=GS Q9VXC7/21-260 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS B7Q4H1/45-217 AC B7Q4H1 #=GS B7Q4H1/45-217 OS Ixodes scapularis #=GS B7Q4H1/45-217 DE Serine protease, putative #=GS B7Q4H1/45-217 DR ORG; Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes; Ixodes scapularis; #=GS F6ZJP1/42-278 AC F6ZJP1 #=GS F6ZJP1/42-278 OS Ornithorhynchus anatinus #=GS F6ZJP1/42-278 DE Serine protease 53 #=GS F6ZJP1/42-278 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS F1N116/160-302 AC F1N116 #=GS F1N116/160-302 OS Bos taurus #=GS F1N116/160-302 DE Serine protease 53 #=GS F1N116/160-302 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS A0A061ICE7/40-273 AC A0A061ICE7 #=GS A0A061ICE7/40-273 OS Cricetulus griseus #=GS A0A061ICE7/40-273 DE Serine protease 53 #=GS A0A061ICE7/40-273 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Cricetidae; Cricetinae; Cricetulus; Cricetulus griseus; #=GS D4AAD2/41-273 AC D4AAD2 #=GS D4AAD2/41-273 OS Rattus norvegicus #=GS D4AAD2/41-273 DE Serine protease 53 #=GS D4AAD2/41-273 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS B4R618/21-260 AC B4R618 #=GS B4R618/21-260 OS Drosophila simulans #=GS B4R618/21-260 DE GD15728 #=GS B4R618/21-260 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4Q1T7/23-264 AC B4Q1T7 #=GS B4Q1T7/23-264 OS Drosophila yakuba #=GS B4Q1T7/23-264 DE Uncharacterized protein #=GS B4Q1T7/23-264 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS B4R0G1/194-440 AC B4R0G1 #=GS B4R0G1/194-440 OS Drosophila simulans #=GS B4R0G1/194-440 DE GD20439 #=GS B4R0G1/194-440 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4HF38/194-440 AC B4HF38 #=GS B4HF38/194-440 OS Drosophila sechellia #=GS B4HF38/194-440 DE GM25869 #=GS B4HF38/194-440 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B3P0N4/195-439 AC B3P0N4 #=GS B3P0N4/195-439 OS Drosophila erecta #=GS B3P0N4/195-439 DE GG21410 #=GS B3P0N4/195-439 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4PTA7/205-449 AC B4PTA7 #=GS B4PTA7/205-449 OS Drosophila yakuba #=GS B4PTA7/205-449 DE Uncharacterized protein, isoform A #=GS B4PTA7/205-449 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GF SQ 17 A1ZAT2/29-266 PCGISTRPKISGGDDAAEPNSIWMAAIFN---SSDFQCGGTIIHMRFVLSAAHCL-------VRGYDLYVRLG----ARNINEPAAVHTVINVFVHHDFIA--SEYRN--DIGLLQLSESIVYTVRVQPICIFLDP-------ALKGSVEKLKTFRALGWGN--RNGKLS-IMLQTIYLLHLKRNECK--------RKLNFNLNSRQICAGTKN--GDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPE---C--RGVGVYTDVTSYVDWISSTIA---R Q9Y122/193-439 -----FSPLQIGGDLVTRGQYPWLAALYEGVGTATYKCVVSVISKRTVITAAHCIYG-----KSASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEG---NPVPDADVGLLVLTSPMVYTKYIRPLCLWGSN--------MGLPPNEGDTGAVAGWGYD-RSAQKT-RFPKTVSVRLVPRDQCLKEM----KRAEDF-ITRRTVCAGNSES-HGPCFGDSGSALIVL-----RNNRWYVRGVVSLSPRHGEICDLSKYVIYCDVARHIDWVRQNMV---M Q4V653/29-260 C-IALFRIRVIGGQNARR--TPWMAYLIR---DNRFACGGSLIAYRFVLTAAHCT-------KINDNLFVRLGEYDSSRTTDGQTRSYRVVSIYRHKNYI----DFRN-HDIAVLKLDRQVVYDAYIRPICILLNS-------GLQSLANSIQNFTLTGWGQMAHYYKMP-TTLQEMSLRRVRNEYCG--------------VPSLSICCWNPV--QYACFGDSGGPLGSLVKY-GHKTIYVQFGVTNSVTGN---C--DGYSSYLDLMSYMPWLYQTLL---- Q8MR00/30-267 PCGISTRPKISGGDDAAEPNSIWMAAIFN---SSDFQCGGTIIHMRFVLSAAHCL-------VRGYDLYVRLG----ARNINEPAAVHTVINVFVHHDFIA--SEYRN--DIGLLQLSESIVYTVRVQPICIFLDP-------ALKGSVEKLKTFRALGWGN--RNGKLS-IMLQTIYLLHLKRNECK--------RKLNFNLNSRQICAGTKN--GDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPE---C--RGVGVYTDVTSYVDWISSTIA---R B7ZWH8/40-273 ------------EGNTLPGEWPWQASVRR---QGVHICSGSLVADTWVLTAAHCFEKMAT--AELSSWSVVLGSL-KQEGQSPGAEEVGVAALQLPKAYN----HYSQGSDLALLQLTHPTV----QTTLCLPQPT----------YHFPFGASCWATGWDQ--NTSDVS-RTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCR----EPDGHWVQVGIISFTSKC---AQEDTPVLLTDMAVHSSWLQAHVH---- Q9VXC7/21-260 A-EASPQGRILGGEDVAQGEYPWSASVRY---NKAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLG----TINQYAGGSIVNVKSVIIHPSYG----NFLH--DIAILELDETLVFSDRIQDIALPPTTDEE--TEDVDAELPNGTPVYVAGWGEL-SDGTAS-YKQQKANYNTLSRSLCE--------WEAGY-GYESVVCLSRAEG-EGICRGDAGAAVI--------DDDKVLRGLTSFNFGP---CGSKYPDVATRVSYYLTWIEANT----- B7Q4H1/45-217 ---QPPEGRVYNGRDAQPGEFPWMVKILM---PTGY-CGGAIITKTHVLTAAHCFDG-----YLAGPIEVIAGLL--------CPKKHTVTHIQRHELYVIGPQDTTY--DLAILKVAPEFEFTKEVYPVKIPVEG------------MEVSGTVAVSGFGTT-HAEPGPVKSLQTTILTVVPSDRCG--------------YPPNIICTEVDQ--TAVC------PVST------------------------------------------------------ F6ZJP1/42-278 ------------EGASTQGEWPWQASVRH---RGTHICSGSLIAEAWVLTAAHCFDRLSV--ADPDSWSVVLGSL-LRDGVGPGAKEAAVVSIQLPGGYN----RYTEGSDLALLQLAPAGLPDGAASPICLPQLG----------HRFPFGASCWATGWGQ--GTGRAP-GTLRNLRLRLISRPTCNCLYNRLHLRALSSPARPGMLCAGAQPGVRGPCQGDSGGPVLCQ----EPDGRWVQAGIISFSTGC---AQEDAPVLLTNLASHAYWLRARA----- F1N116/160-302 -------------------------------------------------------------------------------------------------------------------------LQHEAHTPLCLPRPA----------HRFPFGTSCWATGWYQ--HTNDAP-RTLRNLRLRLISRPTCNCLYNRLHQRSLASPARPGMLCGGPQPGMQGPCQGDSGGPVLCR----EPDGHWVQAGIISFASSC---AREDTPVLLTDMAAHSSWLQARAQGAAF A0A061ICE7/40-273 ------------EGNTLPGEWPWQASVRR---QGVHICSGSLVADAWVLTAAHCFEKVAT--TELSSWSVVLGSL-KQEGLSPGAEEVGVAALQVPKAYN----HYSQGSDLALLQLTHPIA----HTTLCLPQST----------HHFPFGASCWATGWDQ--NTSDVS-RTLRNLRLRLISRPTCNCLYNRLHQRLLASPARPGMLCGGAQPGVQGPCQGDSGGPVMCR----EPDGHWVQVGIVSFTSKC---AQEDTPVLLTDMATHSSWLQAHLH---- D4AAD2/41-273 -------------GNTLPGEWPWQASVRR---QGVHICSGSLVADTWVLTAAHCFEKMAT--AELSSWSVVLGSL-KQEGLSPGAEEVGVAALQLPKAYN----HYSQGSDLALLQLTHPIV----HTTLCLPQPT----------HHFPFGASCWATGWDQ--NTSDVS-RTLRNLRLRLISRPTCNCLYNRLHQRLLANPARSGMLCGGAQPGVQGPCQGDSGGPVMCR----EPDGHWVQVGIISFTSNC---AQEDTPVLLTDMAAHSSWLQAHVD---- B4R618/21-260 A-EASPQGRILGGEDVAQGEYPWSASVRY---NKAHVCSGAIISQTHVLTAAHCVSSVGITPVDASTLAVRVG----TINQYAGGSIVNVKSVLIQPSYG----NFLH--DIAILELAETLVFSDRIAAIALPPKTEEE--TEDVDAELPNGTPVYVAGWGEL-SDGTAS-YKQQKANYNTLSRSLCE--------WEAGY-GYESVVCLSRAEG-EGICRGDAGAPVI--------DDEKVLRGLTSFNFGP---CGSKYPDVATRVSYYLTWIEANT----- B4Q1T7/23-264 T-EATPQGRILGGEDVAQGEYPWSASVRY---NKAHVCSGAIISNNHILTAAHCVSSVGITPVDASTLAVRVG----TINQYAGGSIVNVKSVLIQPSYG----NFLH--DIAILELAESLVFDTRIAAIALPTKEEEEEATEDVDAELPNGTPVYVAGWGEL-ADGTAS-YKQQKANYNTLSRSLCE--------YEAGY-GYESVVCLSRAEG-EGICRGDAGAAVI--------DDDQVLRGLTSFNFGP---CGSKYPDVATRVSYYVNWIEANT----- B4R0G1/194-440 -----FSPLQIGGDLVTRGQYPWLAALYEGAATATYKCVVSVISKRTVITAAHCIYG-----KSASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEG---NPIPDVDVGLLVLTYPMVYTKYIRPLCLWGSN--------MGLPANEGDTGAVAGWGYD-RSAQKT-RFPKTVSVRLVPRDQCLKEM----KRAEDF-ITRRTVCAGNSES-HGPCFGDSGSALIVL-----RNNRWYVRGVVSLSPRQGEICDLSKYVIYCDVARHIDWVRQNMV---M B4HF38/194-440 -----FSPLQIGGDLVTRGQYPWLAALYEGAATATYKCVVSVISKRTVITAAHCIYG-----KSASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEG---NPIPDVDVGLLVLTYPMVYTKYIRPLCLWGSN--------MGLPANEGDTGAVAGWGYD-RSAQKT-RFPKTVSVRLVPRDQCLKEM----KRAEDF-ITRRTVCAGNSES-HGPCFGDSGSALIVL-----RNNRWYVRGVVSLSPRQGEICDLSKYVIYCDVARHIDWVRQNMV---M B3P0N4/195-439 -------PLQIGGDLVTRGQYPWLAALYEGASTVSYKCVVSVISKRTVMTAAHCIYG-----KSASQLWVYLGRHDRNENPENGASLVSVRSVLTPSAYEG---NPVPDADVGLLVLNEPMVYTKYIQPLCLWGSH--------MGLPPNEGDTGAVAGWGYD-RSAQKT-RFPKTVSVRLVPRDQCLKEM----KRAEDF-ITQRTVCAGNSES-HGPCFGDSGSALIVL-----RNNRWYVRGVVSLSPRRGDICDLSKYVIYCDVAKHIDWVRQNMV---M B4PTA7/205-449 -------PLQIGGDLVTRGQYPWLAALYEGGSTATYKCVVTVISKRTVITAAHCIYG-----KSASQLWVYLGRHDRNENPENGASLVSVSSVLTPSAYDG---NPVPDVDVGLLVLTAPMVYTKYIRPLCLWSSN--------MGVSPNEGESGAVAGWGFD-RSAQKT-RFPKTVSVQLVPRDQCLKEM----KRAEDF-ITRRTVCAGNSES-HGPCFGDSGSALIVL-----RNNRWHVRGVVSLSPRQGEICDLSKYVIYCDVAKHIDWVRQNMV---M #=GC scorecons 00000112222354343354367364532000333527354464232656777731200000324434272571101234222453243734533433620000432311745573633336332243565733330000000021223425353355976310444335043554435445474393111000014223303334459453343046493776746642200001243334337546533320004213233434554263374344310000 #=GC scorecons_70 ______________________*_*____________*____*____*_*****_______________*__*________________*________*___________*___*_*______________*__________________________**_______________________*__*_____________________*__________*_**_*_**________________*__*_________________________*__________ #=GC scorecons_80 ______________________*______________*____________****_______________*__*________________*____________________*___*___________________________________________**_______________________*__*_____________________*__________*_**_*___________________*____________________________*__________ #=GC scorecons_90 ______________________________________________________________________________________________________________________________________________________________*___________________________*_____________________*__________*________________________________________________________________ //