# STOCKHOLM 1.0 #=GF ID 2.30.29.240/FF/000006 #=GF DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GF AC 2.30.29.240/FF/000006 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 65.949 #=GS P25455/2-221 AC P25455 #=GS P25455/2-221 OS Drosophila melanogaster #=GS P25455/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II #=GS P25455/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS P25455/2-221 DR GO; GO:0007629; GO:0043153; GO:0070050; GO:1900073; #=GS P25455/2-221 DR EC; 3.1.4.11; #=GS E9FW06/2-225 AC E9FW06 #=GS E9FW06/2-225 OS Daphnia pulex #=GS E9FW06/2-225 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS E9FW06/2-225 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS A0A139WIL1/11-231 AC A0A139WIL1 #=GS A0A139WIL1/11-231 OS Tribolium castaneum #=GS A0A139WIL1/11-231 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A139WIL1/11-231 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7PW25/1-190 AC Q7PW25 #=GS Q7PW25/1-190 OS Anopheles gambiae #=GS Q7PW25/1-190 DE Phosphoinositide phospholipase C #=GS Q7PW25/1-190 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS A0A0P5TMV7/2-225 AC A0A0P5TMV7 #=GS A0A0P5TMV7/2-225 OS Daphnia magna #=GS A0A0P5TMV7/2-225 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0P5TMV7/2-225 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS A0A084VG80/39-231 AC A0A084VG80 #=GS A0A084VG80/39-231 OS Anopheles sinensis #=GS A0A084VG80/39-231 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A084VG80/39-231 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS A0A0Q9W9U6/2-221 AC A0A0Q9W9U6 #=GS A0A0Q9W9U6/2-221 OS Drosophila virilis #=GS A0A0Q9W9U6/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9W9U6/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS B4JDA1/2-221 AC B4JDA1 #=GS B4JDA1/2-221 OS Drosophila grimshawi #=GS B4JDA1/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4JDA1/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; grimshawi group; grimshawi subgroup; Drosophila grimshawi; #=GS A0A0M4EEF0/2-221 AC A0A0M4EEF0 #=GS A0A0M4EEF0/2-221 OS Drosophila busckii #=GS A0A0M4EEF0/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0M4EEF0/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Dorsilopha; Drosophila busckii; #=GS A0A0P5ED59/2-225 AC A0A0P5ED59 #=GS A0A0P5ED59/2-225 OS Daphnia magna #=GS A0A0P5ED59/2-225 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0P5ED59/2-225 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS A0A0P5P8H3/2-225 AC A0A0P5P8H3 #=GS A0A0P5P8H3/2-225 OS Daphnia magna #=GS A0A0P5P8H3/2-225 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0P5P8H3/2-225 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS A0A0N8DL18/2-218 AC A0A0N8DL18 #=GS A0A0N8DL18/2-218 OS Daphnia magna #=GS A0A0N8DL18/2-218 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0N8DL18/2-218 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS A0A1W4UPU2/2-221 AC A0A1W4UPU2 #=GS A0A1W4UPU2/2-221 OS Drosophila ficusphila #=GS A0A1W4UPU2/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A1W4UPU2/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4V3S2/2-221 AC A0A1W4V3S2 #=GS A0A1W4V3S2/2-221 OS Drosophila ficusphila #=GS A0A1W4V3S2/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A1W4V3S2/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4V296/2-221 AC A0A1W4V296 #=GS A0A1W4V296/2-221 OS Drosophila ficusphila #=GS A0A1W4V296/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A1W4V296/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS Q29N33/9-222 AC Q29N33 #=GS Q29N33/9-222 OS Drosophila pseudoobscura pseudoobscura #=GS Q29N33/9-222 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS Q29N33/9-222 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS B4LUP2/2-221 AC B4LUP2 #=GS B4LUP2/2-221 OS Drosophila virilis #=GS B4LUP2/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4LUP2/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS A0A0Q9WRM6/2-220 AC A0A0Q9WRM6 #=GS A0A0Q9WRM6/2-220 OS Drosophila willistoni #=GS A0A0Q9WRM6/2-220 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9WRM6/2-220 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS A0A0Q9X212/2-220 AC A0A0Q9X212 #=GS A0A0Q9X212/2-220 OS Drosophila willistoni #=GS A0A0Q9X212/2-220 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9X212/2-220 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS B4KL19/2-221 AC B4KL19 #=GS B4KL19/2-221 OS Drosophila mojavensis #=GS B4KL19/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4KL19/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; #=GS A0A0Q9X7Z7/2-221 AC A0A0Q9X7Z7 #=GS A0A0Q9X7Z7/2-221 OS Drosophila mojavensis #=GS A0A0Q9X7Z7/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9X7Z7/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; #=GS B4Q625/2-221 AC B4Q625 #=GS B4Q625/2-221 OS Drosophila simulans #=GS B4Q625/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4Q625/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A0Q9WME2/2-221 AC A0A0Q9WME2 #=GS A0A0Q9WME2/2-221 OS Drosophila virilis #=GS A0A0Q9WME2/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9WME2/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS A0A0Q9X0K2/2-220 AC A0A0Q9X0K2 #=GS A0A0Q9X0K2/2-220 OS Drosophila willistoni #=GS A0A0Q9X0K2/2-220 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9X0K2/2-220 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS A0A1W4V2A1/2-221 AC A0A1W4V2A1 #=GS A0A1W4V2A1/2-221 OS Drosophila ficusphila #=GS A0A1W4V2A1/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A1W4V2A1/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A0Q9XI68/2-221 AC A0A0Q9XI68 #=GS A0A0Q9XI68/2-221 OS Drosophila mojavensis #=GS A0A0Q9XI68/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9XI68/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; #=GS B4MTQ4/2-220 AC B4MTQ4 #=GS B4MTQ4/2-220 OS Drosophila willistoni #=GS B4MTQ4/2-220 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4MTQ4/2-220 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS A0A0Q9WKU7/2-221 AC A0A0Q9WKU7 #=GS A0A0Q9WKU7/2-221 OS Drosophila virilis #=GS A0A0Q9WKU7/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9WKU7/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS A0A0Q9XCQ0/2-221 AC A0A0Q9XCQ0 #=GS A0A0Q9XCQ0/2-221 OS Drosophila mojavensis #=GS A0A0Q9XCQ0/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q9XCQ0/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; #=GS B3N7P0/2-221 AC B3N7P0 #=GS B3N7P0/2-221 OS Drosophila erecta #=GS B3N7P0/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B3N7P0/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0Q5WKB5/2-221 AC A0A0Q5WKB5 #=GS A0A0Q5WKB5/2-221 OS Drosophila erecta #=GS A0A0Q5WKB5/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q5WKB5/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0Q5W8P3/2-221 AC A0A0Q5W8P3 #=GS A0A0Q5W8P3/2-221 OS Drosophila erecta #=GS A0A0Q5W8P3/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q5W8P3/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0Q5WFP2/2-221 AC A0A0Q5WFP2 #=GS A0A0Q5WFP2/2-221 OS Drosophila erecta #=GS A0A0Q5WFP2/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0Q5WFP2/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0J9QU17/2-221 AC A0A0J9QU17 #=GS A0A0J9QU17/2-221 OS Drosophila simulans #=GS A0A0J9QU17/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0J9QU17/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A0R1DIL4/2-221 AC A0A0R1DIL4 #=GS A0A0R1DIL4/2-221 OS Drosophila yakuba #=GS A0A0R1DIL4/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0R1DIL4/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A0J9TCG8/2-221 AC A0A0J9TCG8 #=GS A0A0J9TCG8/2-221 OS Drosophila simulans #=GS A0A0J9TCG8/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0J9TCG8/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A0R1DII7/2-221 AC A0A0R1DII7 #=GS A0A0R1DII7/2-221 OS Drosophila yakuba #=GS A0A0R1DII7/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0R1DII7/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS B4P2C8/2-221 AC B4P2C8 #=GS B4P2C8/2-221 OS Drosophila yakuba #=GS B4P2C8/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS B4P2C8/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A0R1DIT6/2-221 AC A0A0R1DIT6 #=GS A0A0R1DIT6/2-221 OS Drosophila yakuba #=GS A0A0R1DIT6/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0R1DIT6/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A0J9QTB1/2-221 AC A0A0J9QTB1 #=GS A0A0J9QTB1/2-221 OS Drosophila simulans #=GS A0A0J9QTB1/2-221 DE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase #=GS A0A0J9QTB1/2-221 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GF SQ 40 P25455/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT E9FW06/2-225 ADSKPGVHVLQLKHVSVPPSMIAGEKFVKWDEDSSLVTAVTLRVDPYGYFLYWTDQNEETQILDMCTIRDTRTGHYAKVPKDSKMRDQVTMGASQD-SLEDKTLTVSYGPDFVNVSFFNFCSSKKETAKQWTDDLLKMANNLLALNGSVHYFLRKAHVRLTLQADKGGKIAVKNIVRTFAQHRDDRRRVEKAFIESTGLASGKDDAIPLSQFGFDDFYRFYKKLT A0A139WIL1/11-231 AAATPS-NAVSLKSIEVPQALQNGEKFIKWDEDSGVGTPVTLRVDKYGFYLHWVDQNHEMDLLDIATIRDTRTGRYAKIPKDPKLRQIVTMG-SQD-TLEEKTVTVCCANDFVNMNFINFCCTRKEIARLWTDALMSLAYNLNQINGTANLYLLKAYTKLILVTDKTGKIPIKNIIKMFAQSRDDKRRIETV-LQSTGLPYGKNDTLSPEKFQFEDFFNFYKNLT Q7PW25/1-190 --------------------------------DSCNGTPVTLRVDVKGFFLYWVDQNHEMDMLDIATIRDVRTGQYAKKPRDMKLRQIVTMG-SQD-TLEEKTVTVCYGADFVNVNFINFCCTRKEIARLWCDELIRMAYNLTQLNGPAIMFLQKAYTKLCLQVDKSGKIPVKNIIKTFATNKDDRRRVEKA-LDVSGLPSGKGDTLALTKFQFEDFFNLYKNLS A0A0P5TMV7/2-225 ADSKPGVHVLQLKHVSVPPSMIAGEKFIKWDEDSSLVTAVTLRVDPNGYFLYWTDQNEETQILDMCTIRDTRTGHYAKVPKDPKMRDQVTMGASQD-SLEDKTLTVSYGPDFVNISFFNFCTSKKETAKQWTDDLLKMANNLLALNGSVHYFLRKAHVRLTLQADKGGKIAVKNIVRTFAQHRDDRRRVEKAFLDSTGLASGKDDAISLSQFGFDDFYRFYKKLT A0A084VG80/39-231 -------------------------GF----EDSCIGTPVTLRVDVKGFFLYWVDQNHEMDMLDIATIRDVRTGQYAKKPRDIKLRQIVTMG-SQD-TLEEKTVTVCYGADFVNVNFINFCCTRKEIARLWCDELIRMAYNLTQLNGPAIMFLQKAYTKLCLQVDKTGKIPVKNIIKTFATNKDDRRRVEKA-LDVSGLPSGKGDTLALAKFQFEDFFNLYKNLS A0A0Q9W9U6/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLSQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT B4JDA1/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFYLHWIDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICYGSDFVNMTFVNFCCTRRDIAQIWSDGLIKLAYSLSQLNGSANMFLLKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0M4EEF0/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFYLHWVDQNNELDILDIATIRDVRTGQYAKKPKDMKLRQIVTLG-QQD-TLEEKTVTICHGSDFVNMTFVNFCCTKRDIAQIWSDGLIKLAYSLSQLNGSAIMFLQKAHTRLCLQVDKTGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0P5ED59/2-225 ADSKPGVHVLQLKHVSVPPSMIAGEKFIKWDEDSSLVTAVTLRVDPNGYFLYWTDQNEETQILDMCTIRDTRTGHYAKVPKDPKMRDQVTMGASQD-SLEDKTLTVSYGPDFVNISFFNFCTSKKETAKQWTDDLLKMANNLLALNGSVHYFLRKAHVRLTLQADKGGKIAVKNIVRTFAQHRDDRRRVEKAFLDSTGLASGKDDAISLSQFGFDDFYRFYKKLT A0A0P5P8H3/2-225 ADSKPGVHVLQLKHVSVPPSMIAGEKFIKWDEDSSLVTAVTLRVDPNGYFLYWTDQNEETQILDMCTIRDTRTGHYAKVPKDPKMRDQVTMGASQD-SLEDKTLTVSYGPDFVNISFFNFCTSKKETAKQWTDDLLKMANNLLALNGSVHYFLRKAHVRLTLQADKGGKIAVKNIVRTFAQHRDDRRRVEKAFLDSTGLASGKDDAISLSQFGFDDFYRFYKKLT A0A0N8DL18/2-218 ADSKPGVHVLQLKHVSVPPSMIAGEKFIKWDEDSSLVTAVTLRVDPNGYFLYWTDQNEETQILDMCTIRDTRTGHYAKVPKDPKMRDQVTMGASQD-SLEDKTLTVSYGPDFVNISFFNFCTSKKETAKQWTDDLLKMANNLLALNGSVHYFLRKAHVRLTLQADKGGKIAVKNIVRTFAQHRDDRRRVEKAFLDSTGLASGKDDAISLSQFGFDXXX------- A0A1W4UPU2/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A1W4V3S2/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A1W4V296/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT Q29N33/9-222 ---------ISTASVEVPQALQDGEKFIRWDDDSGTGLPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKEGKLRQIVTMG-PQDTTLEEKTVTVCHGSDFVNMTFVNFCCNRRDIAQLWCDGLIKLAYSLAQLNGSAIMFLQKAHTRLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKGDSISVSKFQFEDFYNLYKYLT B4LUP2/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLSQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9WRM6/2-220 M--SAGGTYISTASVEVPQALQDGEKFVKWDDDSGSGTPVTMRVDAKGFFLCWVDQNNELDILDIATIRDVRTGQYAKKPKDSKLRQIVTLG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKCL- A0A0Q9X212/2-220 M--SAGGTYISTASVEVPQALQDGEKFVKWDDDSGSGTPVTMRVDAKGFFLCWVDQNNELDILDIATIRDVRTGQYAKKPKDSKLRQIVTLG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKCL- B4KL19/2-221 M--SAGGTYISTASVEVPKALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9X7Z7/2-221 M--SAGGTYISTASVEVPKALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT B4Q625/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9WME2/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLSQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9X0K2/2-220 M--SAGGTYISTASVEVPQALQDGEKFVKWDDDSGSGTPVTMRVDAKGFFLCWVDQNNELDILDIATIRDVRTGQYAKKPKDSKLRQIVTLG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKCL- A0A1W4V2A1/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9XI68/2-221 M--SAGGTYISTASVEVPKALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT B4MTQ4/2-220 M--SAGGTYISTASVEVPQALQDGEKFVKWDDDSGSGTPVTMRVDAKGFFLCWVDQNNELDILDIATIRDVRTGQYAKKPKDSKLRQIVTLG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKCL- A0A0Q9WKU7/2-221 M--SAGGTYISTASVEVPQALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLSQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0Q9XCQ0/2-221 M--SAGGTYISTASVEVPKALQDGEKFIKWDDDSGSGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKKPKDAKLRQIVTMG-PQD-TLEEKTVTICHGSDFVNMTFVNFCCTRRDIAQIWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT B3N7P0/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0Q5WKB5/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0Q5W8P3/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0Q5WFP2/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0J9QU17/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0R1DIL4/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0J9TCG8/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT A0A0R1DII7/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT B4P2C8/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0R1DIT6/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWSDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSIPVSKFQFEDFYNLYKYLT A0A0J9QTB1/2-221 M--SAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLG-PQD-TLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKA-LDVTGLPSGKVDSISVSKFQFEDFYNLYKYLT #=GC scorecons 400346343544446477455447777657769954586996999559789796999595679976999969996999498839796599790699069979969766859999659599966777696495959676966946899764589699767959869959796899977599767798798988087579968994957667696977775577375 #=GC scorecons_70 ______________*_**_____****__*****___********__******_***_*_*****_****_*******_***_****_****__**_************_*****_*_***_******__*_*_*****__*__*****__**_******_**_**_**********_***_**********_**_*******_*_**_***_*****__**_*_ #=GC scorecons_80 _________________________**_____**___*_**_***__******_***_*__***__****_***_***_***_*_*__**_*__**__*****_**__*_****__*_***__*___*__*_*_*_*_*__*__****___**_***_**_**_**_*_*_******_***_*_**_*****_**_***_***_*_*__*_*_****___**_*_ #=GC scorecons_90 ________________________________**___*_**_***__*_**_*_***_*___**__****_***_***_***_*_*__**_*__**__**_**_*___*_****__*_***______*__*_*_*___*__*__***____**_**___*_**_**_*_*_****___**____**_*****_*___**_***_*______*_*___________ //