CATH Superfamily 2.20.25.350
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Eukaryotic translation initiation factor 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Eukaryotic initiation factor eIF2 binding GO:0071074
Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | P55010 (/HDA) P55010 (/HDA) |
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
2 | P55010 (/NAS) P55010 (/NAS) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | P55010 (/TAS) P55010 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P55010 (/IPI) P55010 (/IPI) |
|
Translation factor activity, RNA binding GO:0008135
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
|
2 | P55010 (/TAS) P55010 (/TAS) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
2 | P55010 (/HDA) P55010 (/HDA) |
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
1 | Q07205 (/IDA) |
|
Eukaryotic initiation factor eIF2 binding GO:0071074
Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.
|
1 | Q07205 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Formation of translation preinitiation complex GO:0001731
The joining of the small ribosomal subunit, ternary complex, and mRNA.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
|
2 | P55010 (/NAS) P55010 (/NAS) |
|
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
|
2 | P55010 (/IDA) P55010 (/IDA) |
|
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
|
2 | P55010 (/TAS) P55010 (/TAS) |
|
Formation of translation preinitiation complex GO:0001731
The joining of the small ribosomal subunit, ternary complex, and mRNA.
|
1 | Q07205 (/IDA) |
|
Formation of translation preinitiation complex GO:0001731
The joining of the small ribosomal subunit, ternary complex, and mRNA.
|
1 | Q07205 (/IMP) |
|
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q07205 (/IDA) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | A0A024R6Q1 (/IDA) A0A024R6Q1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YN40 (/IDA) P55010 (/IDA) P55010 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | A0A024R6Q1 (/IDA) A0A024R6Q1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YLZ1 (/IDA) H0YN40 (/IDA) P55010 (/IDA) P55010 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | P59325 (/ISO) P59325 (/ISO) P59325 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P55010 (/IDA) P55010 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P55010 (/TAS) P55010 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P55010 (/NAS) P55010 (/NAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P55010 (/TAS) P55010 (/TAS) |
