# STOCKHOLM 1.0
#=GF ID 2.170.150.10/FF/000005
#=GF DE Guanine nucleotide exchange factor MSS4
#=GF AC 2.170.150.10/FF/000005
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 94.870
#=GS Q9VLP3/10-120       AC Q9VLP3
#=GS Q9VLP3/10-120       OS Drosophila melanogaster
#=GS Q9VLP3/10-120       DE Guanine nucleotide exchange factor MSS4 homolog
#=GS Q9VLP3/10-120       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS Q9VLP3/10-120       DR GO; GO:0005829; GO:0008270; GO:0016020; GO:0017112; GO:0043547; GO:0045180; GO:0061865; 
#=GS O43057/1-99         AC O43057
#=GS O43057/1-99         OS Schizosaccharomyces pombe 972h-
#=GS O43057/1-99         DE Guanine nucleotide exchange factor MSS4 homolog
#=GS O43057/1-99         DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS O43057/1-99         DR GO; GO:0005085; GO:0006892; GO:0007264; GO:0008270; 
#=GS Q9U1X4/1-85         AC Q9U1X4
#=GS Q9U1X4/1-85         OS Caenorhabditis elegans
#=GS Q9U1X4/1-85         DE Putative guanine nucleotide exchange factor MSS4 homolog
#=GS Q9U1X4/1-85         DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS Q9U1X4/1-85         DR GO; GO:0008270; 
#=GS Q7YWN1/32-141       AC Q7YWN1
#=GS Q7YWN1/32-141       OS Caenorhabditis elegans
#=GS Q7YWN1/32-141       DE Uncharacterized protein
#=GS Q7YWN1/32-141       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A0A1B2AJA9/10-120   AC A0A1B2AJA9
#=GS A0A1B2AJA9/10-120   OS Drosophila melanogaster
#=GS A0A1B2AJA9/10-120   DE GEO07782p1
#=GS A0A1B2AJA9/10-120   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS B0G120/54-163       AC B0G120
#=GS B0G120/54-163       OS Dictyostelium discoideum
#=GS B0G120/54-163       DE Mss4-like family protein
#=GS B0G120/54-163       DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; 
#=GS B0G120/54-163       DR GO; GO:0008270; 
#=GS E9G821/1-109        AC E9G821
#=GS E9G821/1-109        OS Daphnia pulex
#=GS E9G821/1-109        DE Uncharacterized protein
#=GS E9G821/1-109        DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; 
#=GS E3JXA3/23-132       AC E3JXA3
#=GS E3JXA3/23-132       OS Puccinia graminis f. sp. tritici CRL 75-36-700-3
#=GS E3JXA3/23-132       DE Uncharacterized protein
#=GS E3JXA3/23-132       DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia graminis; 
#=GS B3RVB9/17-134       AC B3RVB9
#=GS B3RVB9/17-134       OS Trichoplax adhaerens
#=GS B3RVB9/17-134       DE Uncharacterized protein
#=GS B3RVB9/17-134       DR ORG; Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax; Trichoplax adhaerens; 
#=GS Q7Q852/13-128       AC Q7Q852
#=GS Q7Q852/13-128       OS Anopheles gambiae
#=GS Q7Q852/13-128       DE AGAP008798-PA
#=GS Q7Q852/13-128       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; 
#=GS A9V3X0/24-136       AC A9V3X0
#=GS A9V3X0/24-136       OS Monosiga brevicollis
#=GS A9V3X0/24-136       DE Predicted protein
#=GS A9V3X0/24-136       DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; 
#=GS F0ZFC8/54-160       AC F0ZFC8
#=GS F0ZFC8/54-160       OS Dictyostelium purpureum
#=GS F0ZFC8/54-160       DE Uncharacterized protein
#=GS F0ZFC8/54-160       DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; 
#=GS A0A369SBK8/17-134   AC A0A369SBK8
#=GS A0A369SBK8/17-134   OS Trichoplax sp. H2
#=GS A0A369SBK8/17-134   DE Guanine nucleotide exchange factor MSS4
#=GS A0A369SBK8/17-134   DR ORG; Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax; Trichoplax sp. H2; 
#=GS G0NR92/32-141       AC G0NR92
#=GS G0NR92/32-141       OS Caenorhabditis brenneri
#=GS G0NR92/32-141       DE Uncharacterized protein
#=GS G0NR92/32-141       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; 
#=GS A8WTI9/32-141       AC A8WTI9
#=GS A8WTI9/32-141       OS Caenorhabditis briggsae
#=GS A8WTI9/32-141       DE Protein CBG02782
#=GS A8WTI9/32-141       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS E3LF08/32-141       AC E3LF08
#=GS E3LF08/32-141       OS Caenorhabditis remanei
#=GS E3LF08/32-141       DE Uncharacterized protein
#=GS E3LF08/32-141       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; 
#=GS A0A1I7UC57/32-141   AC A0A1I7UC57
#=GS A0A1I7UC57/32-141   OS Caenorhabditis tropicalis
#=GS A0A1I7UC57/32-141   DE Uncharacterized protein
#=GS A0A1I7UC57/32-141   DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis tropicalis; 
#=GS A0A2G5V3C9/32-141   AC A0A2G5V3C9
#=GS A0A2G5V3C9/32-141   OS Caenorhabditis nigoni
#=GS A0A2G5V3C9/32-141   DE Uncharacterized protein
#=GS A0A2G5V3C9/32-141   DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A261BXV6/323-432  AC A0A261BXV6
#=GS A0A261BXV6/323-432  OS Caenorhabditis latens
#=GS A0A261BXV6/323-432  DE Uncharacterized protein
#=GS A0A261BXV6/323-432  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; 
#=GS A0A182LHU1/13-128   AC A0A182LHU1
#=GS A0A182LHU1/13-128   OS Anopheles coluzzii
#=GS A0A182LHU1/13-128   DE Uncharacterized protein
#=GS A0A182LHU1/13-128   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles coluzzii; 
#=GS A0A182IB42/13-128   AC A0A182IB42
#=GS A0A182IB42/13-128   OS Anopheles arabiensis
#=GS A0A182IB42/13-128   DE Uncharacterized protein
#=GS A0A182IB42/13-128   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles arabiensis; 
#=GS A0A182X618/13-128   AC A0A182X618
#=GS A0A182X618/13-128   OS Anopheles quadriannulatus
#=GS A0A182X618/13-128   DE Uncharacterized protein
#=GS A0A182X618/13-128   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles quadriannulatus; 
#=GS G0P3Y5/32-141       AC G0P3Y5
#=GS G0P3Y5/32-141       OS Caenorhabditis brenneri
#=GS G0P3Y5/32-141       DE Uncharacterized protein
#=GS G0P3Y5/32-141       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; 
#=GS A8WQV1/94-203       AC A8WQV1
#=GS A8WQV1/94-203       OS Caenorhabditis briggsae
#=GS A8WQV1/94-203       DE Protein CBR-MDT-9
#=GS A8WQV1/94-203       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS B4Q6Q4/10-120       AC B4Q6Q4
#=GS B4Q6Q4/10-120       OS Drosophila simulans
#=GS B4Q6Q4/10-120       DE GD23523
#=GS B4Q6Q4/10-120       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; 
#=GS A0A1W4V7E1/10-120   AC A0A1W4V7E1
#=GS A0A1W4V7E1/10-120   OS Drosophila ficusphila
#=GS A0A1W4V7E1/10-120   DE guanine nucleotide exchange factor MSS4 homolog
#=GS A0A1W4V7E1/10-120   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; 
#=GS B4HYI6/10-120       AC B4HYI6
#=GS B4HYI6/10-120       OS Drosophila sechellia
#=GS B4HYI6/10-120       DE GM16890
#=GS B4HYI6/10-120       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; 
#=GS B3N741/10-120       AC B3N741
#=GS B3N741/10-120       OS Drosophila erecta
#=GS B3N741/10-120       DE Uncharacterized protein
#=GS B3N741/10-120       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; 
#=GS B4NWW2/11-120       AC B4NWW2
#=GS B4NWW2/11-120       OS Drosophila yakuba
#=GS B4NWW2/11-120       DE Uncharacterized protein
#=GS B4NWW2/11-120       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; 
#=GF SQ 29
Q9VLP3/10-120               ----QITDGK-NKSNVRC--QFCNCLMLKA-QEGTYNQEE-VDVPLMTQKQ---DRTADSLNSEPLKDFWLVKDMMTFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCY-LALKRVVHK
O43057/1-99                 ----------MSNLRIVC--QHCPSVVFNN-KRPDVVKRP--TMSAMLHSE-----TQEDLETD---DFFLLKDPFAFDNVSVSKPLANN----YKLLACADCEKGPLGYYDSKNN-EYL-LLCSLEK--
Q9U1X4/1-85                 -------------------------------MTTEYLDEE-RDLPLPRQKK-----GIDHTQTEPIRGFFGVKDMFAFENVGFTRSSEGK-----RYLVCGECEQGPVGFVDPVTE-MNY-VSPERLD-V
Q7YWN1/32-141               --DLINEDDR-NLHKVVC--RRCKSVIFPE-DVVMTVENQPYQLRVMTH------QAKGPLAQEKISWWWYTENDMIFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A0A1B2AJA9/10-120           ----QITDGK-NKSNVRC--QFCNCLMLKA-QEGTYNQEE-VDVPLMTQKQ---DRTADSLNSEPLKDFWLVKDMMTFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCY-LALKRVVHK
B0G120/54-163               LTETRDETSRDLLKTIHC--RLCDCKILTP-NNAKLVEKQ-ITFIHKKQSN----------TAEQLKYMWFLPDMFSFENIAFSKDVNAT----HKYLTCAECEAEVIGIHYISSK-ENY-VAHDRIVYK
E9G821/1-109                ----MSDGEK-NAARFGC--LTCPSVILLA-GVGTLVKTE-FKLPLATKTS-----KDEDEETEFVTKSWLIPDMFQFENVGFSKTVGNY-----KYLVCADCEIGPIGWHCIDSK-ESY-VADQRVKHM
E3JXA3/23-132               --MILHLPSK-NPSKLLCPIESCRCIILRK-DVGRLVTVQECPLP----------EPPHLTSTGPSTRCWLVPSPTSFENIGFSKPVGQVAGNERRWLSCGACDFGPLGWTESPTN-----LA-KQFAND
B3RVB9/17-134               --HQLTADGK-NAQMIIC--PNCRCKILLK-KTAELVNTD-IFLPYMRVKKNTSNQESGQVDGEQLSQFWKVDNMFTFENVGFTKTVGSS----IKYLICADCEIGPIGWHDINDK-TTFLIATQRIHYS
Q7Q852/13-128               --ALVNEDGK-NKTNVKC--DRCGSLILKS-TNSDYDTTE-FVLPLAKQKRQPVEQEAEEFTTETLKDFWMVKDMYTFENIGFSNTVDNR-----KYLTCADCEVGPIGYHDLETK-KSY-IALARVKHE
A9V3X0/24-136               --VLVNESNG-NILRIRC--CFCNSPVFSK-SAATATHTP-VQLPKMVQRG-----AEGETVTDTCEHWWQVKDMYDFDNVGFSKTVDGV-----KYLACADCEIGPIGYHDPSAEPKTFNIAHARIRYT
F0ZFC8/54-160               --ETRNEEGF-LLKTIHC--RLCDCKILTP-KNAKLVEKQ-ITLINKKQSN----------TAEDLKYMWFLPDMFQFENIAFTKDVNST----HKYLSCAECEQEVIGIHYIGSK-ENY-VAHDRIIYK
A0A369SBK8/17-134           --HQLTADGK-NAQMIIC--PNCRCKILLK-KTAELVNTD-IFLPYMRVKKNTSNQESGQVDGEQLSQFWKVDNMFTFENVGFTKTVGSS----IKYLICADCEIGPIGWHDINDK-TTFLIATQRIHYS
G0NR92/32-141               --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMSH------QAKGPPAVEKISWWWYTENDMVFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A8WTI9/32-141               --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMTH------QGKGASSFEKISWWWYTESDMVFDTVGW-QTIDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
E3LF08/32-141               --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMTH------QAKGPAAFEKISWWWYTESDMVFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A0A1I7UC57/32-141           --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMAVENQPYPLRVMTH------QAKGPLAQEKISWWWYTENDMVFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVRYD
A0A2G5V3C9/32-141           --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMTH------QGKGAPSFEKISWWWYTESDMVFDTVGW-QTIDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A0A261BXV6/323-432          --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMTH------QAKGPAAFEKISWWWYTESDMVFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A0A182LHU1/13-128           --ALVNEDGK-NKTNVKC--DRCGSLILKS-TNSDYDTTE-FVLPLAKQKRQPVEQEAEEFTTETLKDFWMVKDMYTFENIGFSNTVDNR-----KYLTCADCEVGPIGYHDLETK-KSY-IALARVKHE
A0A182IB42/13-128           --ALVNEDGK-NKTNVKC--DRCGSLILKS-TNSDYDTTE-FVLPLAKQKRQPVEQEAEEFTTETLKDFWMVKDMYTFENIGFSNTVDNR-----KYLTCADCEVGPIGYHDLETK-KSY-IALARVKHE
A0A182X618/13-128           --ALVNEDGK-NKTNVKC--DRCGSLILKS-TNSDYDTTE-FVLPLAKQKRQPVEQEAEEFTTETLKDFWMVKDMYTFENIGFSNTVDNR-----KYLTCADCEVGPIGYHDLETK-KSY-IALARVKHE
G0P3Y5/32-141               --DLINEDDR-NLHKIVC--RRCKSVIFPE-DVVMTVDNQPYQLRVMSH------QAKGPPAVETISWWWYTENDMVFDTVGW-QTVDKK-----KVLMCGDCELGPIGFRSEDNK-KFW-VAVERVKYE
A8WQV1/94-203               ----FSLDARTNEDTLIC--KECKTVVILKNMTTEFLNEE-RDLPLPRQKK-----GIDHTQTEPVRGYFGVKDIFAFENVGFTRSSEGK-----RYLVCGECEQGPVGFVDTLTE-MNY-VTPERLA-V
B4Q6Q4/10-120               ----QITDGK-NKSNVRC--QFCNSLMLKA-QEGTYNQEE-VDVPLMMQKQ---DRTADSLNSEPLKDFWLVKDMMTFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCY-LALKRVVHK
A0A1W4V7E1/10-120           ----QIADGK-NKTNVRC--QFCNSLMLKA-QEGTHSQEE-VDVPLMMQKQ---DKTADNLNSEPLKDFWLVKDMMMFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCF-LALKRVVHK
B4HYI6/10-120               ----QITDGK-NKSNVRC--QFCNSLMLKA-QEGTYNQEE-VDVPLMMQKQ---DRSADSLNSEPLKDFWLVKDMMTFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCY-LALKRVVHK
B3N741/10-120               ----QITDGK-NKSNVRC--QFCNSLMLKA-QEGAYNQEK-VDVPLMMQKQ---DQTADSLNSEPLKDFWLVKDMMTFENIGFSNTVDGR-----KFLVCADCERGPVGYHDLSTR-HCF-LALQRVVHK
B4NWW2/11-120               -----IVDGK-NKSNVRC--QFCNSLMLKA-QEGTYNQEE-VDVPLMMQKQ---DRTADSLNSEPLKDFWLVKDMMTFENIGFSNTLDGR-----KFLVCADCERGPVGYHDLSTR-HCF-LALKRVVHK
#=GC scorecons              0012233545063345380033835465330334334445033654435220000333423337354347354544497677535666440000084949679838769555345604340673476353
#=GC scorecons_70           ___________*_____*____*____________________*___________________*_____*_______*****___**________*_*_*****_****_____________*__*____
#=GC scorecons_80           _________________*____*________________________________________*_____*_______**__*_____________*_*_*_***_**_*_____________*__*____
#=GC scorecons_90           _________________*____*______________________________________________________*_________________*_*_*__**_*__*_____________________
//