# STOCKHOLM 1.0 #=GF ID 2.130.10.30/FF/000051 #=GF DE Highwire, isoform B #=GF AC 2.130.10.30/FF/000051 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 69.216 #=GS Q9NB71/552-807 AC Q9NB71 #=GS Q9NB71/552-807 OS Drosophila melanogaster #=GS Q9NB71/552-807 DE E3 ubiquitin-protein ligase highwire #=GS Q9NB71/552-807 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9NB71/552-807 DR GO; GO:0004842; GO:0005515; GO:0005886; GO:0006914; GO:0007616; GO:0007628; GO:0008270; GO:0008582; GO:0010629; GO:0016567; GO:0030514; GO:0031410; GO:0040011; GO:0045886; GO:0048678; GO:0050808; GO:2000331; #=GS X2JF19/552-807 AC X2JF19 #=GS X2JF19/552-807 OS Drosophila melanogaster #=GS X2JF19/552-807 DE Highwire, isoform B #=GS X2JF19/552-807 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A7US37/323-584 AC A7US37 #=GS A7US37/323-584 OS Anopheles gambiae #=GS A7US37/323-584 DE AGAP011177-PA #=GS A7US37/323-584 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS E9H1S2/376-670 AC E9H1S2 #=GS E9H1S2/376-670 OS Daphnia pulex #=GS E9H1S2/376-670 DE Uncharacterized protein #=GS E9H1S2/376-670 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS C3ZT19/456-686 AC C3ZT19 #=GS C3ZT19/456-686 OS Branchiostoma floridae #=GS C3ZT19/456-686 DE Uncharacterized protein #=GS C3ZT19/456-686 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS A0A1W4VFP9/552-807 AC A0A1W4VFP9 #=GS A0A1W4VFP9/552-807 OS Drosophila ficusphila #=GS A0A1W4VFP9/552-807 DE E3 ubiquitin-protein ligase highwire #=GS A0A1W4VFP9/552-807 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3NUW1/552-807 AC B3NUW1 #=GS B3NUW1/552-807 OS Drosophila erecta #=GS B3NUW1/552-807 DE Uncharacterized protein #=GS B3NUW1/552-807 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4IJ87/552-807 AC B4IJ87 #=GS B4IJ87/552-807 OS Drosophila sechellia #=GS B4IJ87/552-807 DE GM12011 #=GS B4IJ87/552-807 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS C3ZT14/260-490 AC C3ZT14 #=GS C3ZT14/260-490 OS Branchiostoma floridae #=GS C3ZT14/260-490 DE Uncharacterized protein #=GS C3ZT14/260-490 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GF SQ 9 Q9NB71/552-807 -----------------------------------------------ARKKFRTLGYAAFEDELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKCVGR------TPTLKLTELV-ISKAAN-IVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSK-NRRQPKAVKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDA-MGFVSELLEQHVTKVALGKAHCVALNAKGQLFSFGLNNKGQCGRIF---NKLQPVKDVPPFASSSTAAAC---- X2JF19/552-807 -----------------------------------------------ARKKFRTLGYAAFEDELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKCVGR------TPTLKLTELV-ISKAAN-IVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSK-NRRQPKAVKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDA-MGFVSELLEQHVTKVALGKAHCVALNAKGQLFSFGLNNKGQCGRIF---NKLQPVKDVPPFASSSTAAAC---- A7US37/323-584 ---------------------------------------------KLAKNRYHTYGWAAFEEELVENGSMAAPPPPPASIAPMPVLESNPTGAAIQSISCGKEFGLVLVDDGKVLYWGRGTALGLKTAPK-----ATVSMKLSELTALPKGVSCFRQVAVGHEANHGLLLTGDGTVYFTGTAKRGEDGELAKTNRRQPKAIKPKRLNKLDGQTITFVACNNGTSAFVTKDGKLIMYGKDTNYCEP-NGVVGGLTDVVIRKVALGKAHCVAVDALGQLYTFGLNNKGQCGRKF-------QRERNGECGFKSVIMSVLSSN E9H1S2/376-670 IGKNSSLFSDGNRLGSVFKTDEDELHATLFEINKGELFSFGESRLRLALQSLYIVGASINDENT------------------DLRQINFNADEGFTSIVAGKEFMLMVSSSGKVSYQGKASSLGLKTVGELVHNQEQTSNRWYELP-LPKSPS-IVRCATGHDGFHAVFLGADGTAFFAGLAKRGEDGDLTK-HRRQQKSSRPKRFSSIEGKVVVDIACNNGSSAMVTKDGELFLFGKDSTYCESTSGRLLGIKDR-IVKVALGKAHGVTLTDKGVVYTFGINNKGQCGRDLFSSSQTKQSENNSQLQSTTLLSAC---K C3ZT19/456-686 ----------------------------------------------------DLCGWANFDQNQ------------------ELHTTSLGVDEEVVSVTSGKDIAIIRTTSGKLLYTGKSQQLGIKQGGP-------PLGKWAELP-ITKSPR-VVQCSMGHEGVHGLLVSEDGSVFFCGTARRGEDGDQVK-RARQPKPSKPKKMIKLEGRHVVWSACNVGSSAVVTKEGELYMFGKDTAYADTTTGLISDLKEEAVTQISLGKAHACVLTAKGEVFTFGVNNKGQCGRDF---TP--QQKEGASAGAMAVGAED---- A0A1W4VFP9/552-807 -----------------------------------------------ARKKFRTLGYAAFEDELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVLGMACGKEFGLVRASNGRVYYYGKSAALGLKCVGR------TPTLKLTELV-ISKAAN-IVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSK-NRRQPKAVKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDA-MGFVSELLDQHVTKVALGKAHCVALNAKGQLFSFGLNNKGQCGRIF---NKLQPVKDVPPFASSSTAAAC---- B3NUW1/552-807 -----------------------------------------------ARKKFRTLGYAAFEDELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKCVGR------TPTLKLTELV-ISKAAN-IVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSK-NRRQPKAIKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDA-MGFVSELLDQHVTKVALGKAHCVALNAKGQLFSFGLNNKGQCGRIF---NKLQPVKDVPPFASSSTAAAC---- B4IJ87/552-807 -----------------------------------------------ARKKFRTLGYAAFEDELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKCVGR------TPTLKLTELV-ISKAAN-IVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSK-NRRQPKAVKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDA-MGFVSELLEQHVTKVALGKAHCVALNAKGQLFSFGLNNKGQCGRIF---NKLQPVKDVPPFASSSTAAAC---- C3ZT14/260-490 ---------------------------------------------------LDLCGWANFDQNQ------------------ELHTTSLGVDEEVVSVTSGKDIAIIRTTSGKLLYTGKSQQLGIKQGGP-------PLGKWAELP-ITKSPR-VVQCSMGHEGVHGLLVSEDGSVFFCGTARRGEDGDQVK-RARQPKPSKPKKMIKLEGRHVVWSACNVGSSAVVTKEGELYMFGKDTAYADTTTGLISDLKEEAVTQVSLGKAHACVLTAKGEVFTFGVNNKGQCGRDF---TP--QQKEGAPAGAMAVGAE----- #=GC scorecons 00000000000000000000000000000000000000000000000422243439374665541111111111111121124733343457446365459976466445597649397544996934740000002543743994064955405654659967495776449967895969799999734905599695479976466695477349995959959994959477999757574139365573642756869999945575669467699599999999370003311536434434435435430000 #=GC scorecons_70 _______________________________________________________*_*__*______________________*_______*________***__*_____***_*_**___****__*___________*__**__*_*_____*__*_****_*_***__******_**********__*___****__****__****__**__***_*_**_***_*_*_******_*_*___*____*_*__*_********___*_***__*_**_********_*____________________________ #=GC scorecons_80 _______________________________________________________*___________________________*_______*________***________*___*_**___**_*______________*__**____*__________**_*_*_**___**__**_*_*_******__*___**_*__***______*__**__***_*_**_***_*_*_*****________*____*_______*_*****___*___*__*_**_********_*____________________________ #=GC scorecons_90 _______________________________________________________*____________________________________________**_________*___*_*____**_*_________________**____*__________**___*______**__**_*_*_*****___*___**_*___**______*______***_*_**_***_*_*___***________*______________*****_______*____**_********______________________________ //