# STOCKHOLM 1.0
#=GF ID 2.130.10.30/FF/000037
#=GF DE Inhibitor of Bruton tyrosine kinase
#=GF AC 2.130.10.30/FF/000037
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 23.939
#=GS Q6ZPR6/132-387      AC Q6ZPR6
#=GS Q6ZPR6/132-387      OS Mus musculus
#=GS Q6ZPR6/132-387      DE Inhibitor of Bruton tyrosine kinase
#=GS Q6ZPR6/132-387      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; 
#=GS Q6ZPR6/132-387      DR GO; GO:0001933; GO:0005654; GO:0005737; GO:0019901; GO:0030292; GO:0051209; 
#=GS A0A087WNN3/135-393  AC A0A087WNN3
#=GS A0A087WNN3/135-393  OS Mus musculus
#=GS A0A087WNN3/135-393  DE Inhibitor of Bruton tyrosine kinase
#=GS A0A087WNN3/135-393  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; 
#=GS G1PP31/135-392      AC G1PP31
#=GS G1PP31/135-392      OS Myotis lucifugus
#=GS G1PP31/135-392      DE Uncharacterized protein
#=GS G1PP31/135-392      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae; Myotis; Myotis lucifugus; 
#=GS G3T1V7/136-393      AC G3T1V7
#=GS G3T1V7/136-393      OS Loxodonta africana
#=GS G3T1V7/136-393      DE Uncharacterized protein
#=GS G3T1V7/136-393      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Afrotheria; Proboscidea; Elephantidae; Loxodonta; Loxodonta africana; 
#=GS H0X5V3/135-394      AC H0X5V3
#=GS H0X5V3/135-394      OS Otolemur garnettii
#=GS H0X5V3/135-394      DE Uncharacterized protein
#=GS H0X5V3/135-394      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur; Otolemur garnettii; 
#=GS A0A452UVJ8/135-396  AC A0A452UVJ8
#=GS A0A452UVJ8/135-396  OS Ursus maritimus
#=GS A0A452UVJ8/135-396  DE Uncharacterized protein
#=GS A0A452UVJ8/135-396  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus maritimus; 
#=GS A0A091DIR7/135-392  AC A0A091DIR7
#=GS A0A091DIR7/135-392  OS Fukomys damarensis
#=GS A0A091DIR7/135-392  DE Inhibitor of Bruton tyrosine kinase
#=GS A0A091DIR7/135-392  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys; Fukomys damarensis; 
#=GS A0A3Q0CXL4/137-394  AC A0A3Q0CXL4
#=GS A0A3Q0CXL4/137-394  OS Mesocricetus auratus
#=GS A0A3Q0CXL4/137-394  DE inhibitor of Bruton tyrosine kinase
#=GS A0A3Q0CXL4/137-394  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Cricetidae; Cricetinae; Mesocricetus; Mesocricetus auratus; 
#=GS A0A452S979/135-396  AC A0A452S979
#=GS A0A452S979/135-396  OS Ursus americanus
#=GS A0A452S979/135-396  DE Inhibitor of Bruton tyrosine kinase
#=GS A0A452S979/135-396  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; 
#=GS A0A3Q7X8I4/135-393  AC A0A3Q7X8I4
#=GS A0A3Q7X8I4/135-393  OS Ursus arctos horribilis
#=GS A0A3Q7X8I4/135-393  DE inhibitor of Bruton tyrosine kinase isoform X1
#=GS A0A3Q7X8I4/135-393  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus arctos; Ursus arctos horribilis; 
#=GS A0A384BLU8/135-393  AC A0A384BLU8
#=GS A0A384BLU8/135-393  OS Ursus maritimus
#=GS A0A384BLU8/135-393  DE inhibitor of Bruton tyrosine kinase
#=GS A0A384BLU8/135-393  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus maritimus; 
#=GS A0A3Q7VNZ6/135-393  AC A0A3Q7VNZ6
#=GS A0A3Q7VNZ6/135-393  OS Ursus arctos horribilis
#=GS A0A3Q7VNZ6/135-393  DE inhibitor of Bruton tyrosine kinase isoform X3
#=GS A0A3Q7VNZ6/135-393  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus arctos; Ursus arctos horribilis; 
#=GS A0A452S907/132-388  AC A0A452S907
#=GS A0A452S907/132-388  OS Ursus americanus
#=GS A0A452S907/132-388  DE Inhibitor of Bruton tyrosine kinase
#=GS A0A452S907/132-388  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; 
#=GS A0A452S871/135-393  AC A0A452S871
#=GS A0A452S871/135-393  OS Ursus americanus
#=GS A0A452S871/135-393  DE Inhibitor of Bruton tyrosine kinase
#=GS A0A452S871/135-393  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; 
#=GS A0A452UVB1/136-395  AC A0A452UVB1
#=GS A0A452UVB1/136-395  OS Ursus maritimus
#=GS A0A452UVB1/136-395  DE Uncharacterized protein
#=GS A0A452UVB1/136-395  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus maritimus; 
#=GF SQ 15
Q6ZPR6/132-387              THVVFKDTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPPASCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGG---------
A0A087WNN3/135-393          ---VFKDTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPPASCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKV---
G1PP31/135-392              ---VFKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAEDHTIVLTEDGCIYTFGRNTFHQLGIIPPPSSCNVPRQMQAKHLKGRTIIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLTDYQCKKMASKQLNLKKVLVSGGRLEYK----
G3T1V7/136-393              ----FKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLSGHSCSQVAAAKDHTVVLTEDGCVYTFGLNVFHQLGLIPPPPSCNVPRQMQAKYLKGKTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHRDIGLSLVAASDGATVCVTTRGDIYLLADYQCKKMASKQLNLKKVLVSGGRMEYKV---
H0X5V3/135-394              ---VFKSTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFPRSGVSIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSLVAAAEDHTVVLTEDGCVYTFGLNVFHQLGIIPPPSSCNVPRQMQGKYLKGRTIIGVAAGKFHTVLWTRDAVYTLGLNGGQLGYLLDPNGERCVTAPRQVSALHHKDVTLSLVAASDGATVCVTTRGDVYLLADYQCKKMASKQLNLKKVLVSGGYMEYKVD--
A0A452UVJ8/135-396          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKVDPE
A0A091DIR7/135-392          ---VFKSTDPTDVYTWGDNTNFTLGHGGQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLTQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSRCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDINLSLVAASDGATVCVTTRGDIYLLADYQCKKMASKQLNLKKILVSGGRMEYK----
A0A3Q0CXL4/137-394          ----FKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTFGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKV---
A0A452S979/135-396          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKVDPE
A0A3Q7X8I4/135-393          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKV---
A0A384BLU8/135-393          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKV---
A0A3Q7VNZ6/135-393          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKV---
A0A452S907/132-388          THVVFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGR--------
A0A452S871/135-393          ---VFKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKV---
A0A452UVB1/136-395          ----FKTTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLIPRLVEGLSGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPASCNVPRQMQAKYLKGRTVIGVAAGRFHTVLWTREAVYTMGLNGGQLGYLPDPNGEKYVTAPRQVSALHHKDITLSLVAASDGATVCVTTRGDIYLLADYQCKKMASRQLNLKKVLVSGGRMEYKVDP-
#=GC scorecons              0005994999979999999999999998999999999799989998779999999999999899999999999699999999999997999999979989979999799989997999899997969999989999589999997989899979799999989999999889999699999999795999998699699999999989856999999999999999999899989999999967999999899999455553000
#=GC scorecons_70           ____**_******************************************************************_***************************************************_**********_*************************************************_**********************_**********************************************_________
#=GC scorecons_80           ____**_******************************************************************_*************_*************************************_**********_*******_*********_********************_**********_******_**_************__*******************************__************_________
#=GC scorecons_90           ____**_****_*************************_***_****__*************************_*************_*******_*****_****_*******_********_*_**********_*******_*_*****_*_********************_********_*_******_**_************__*******************************__************_________
//