# STOCKHOLM 1.0 #=GF ID 2.130.10.30/FF/000030 #=GF DE Secretion-regulating guanine nucleotide exchange factor #=GF AC 2.130.10.30/FF/000030 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 41.792 #=GS Q9UGK8/251-404 AC Q9UGK8 #=GS Q9UGK8/251-404 OS Homo sapiens #=GS Q9UGK8/251-404 DE Secretion-regulating guanine nucleotide exchange factor #=GS Q9UGK8/251-404 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q9UGK8/251-404 DR GO; GO:0005087; GO:0005515; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0016235; GO:0043231; GO:0050709; #=GS Q80YD6/248-407 AC Q80YD6 #=GS Q80YD6/248-407 OS Mus musculus #=GS Q80YD6/248-407 DE Secretion-regulating guanine nucleotide exchange factor #=GS Q80YD6/248-407 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q80YD6/248-407 DR GO; GO:0005087; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0016235; GO:0043231; GO:0050709; #=GS H0X4B1/250-402 AC H0X4B1 #=GS H0X4B1/250-402 OS Otolemur garnettii #=GS H0X4B1/250-402 DE Uncharacterized protein #=GS H0X4B1/250-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur; Otolemur garnettii; #=GS F6YFG6/256-407 AC F6YFG6 #=GS F6YFG6/256-407 OS Callithrix jacchus #=GS F6YFG6/256-407 DE Secretion regulating guanine nucleotide exchange factor #=GS F6YFG6/256-407 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS D3ZN16/249-415 AC D3ZN16 #=GS D3ZN16/249-415 OS Rattus norvegicus #=GS D3ZN16/249-415 DE Secretion-regulating guanine nucleotide exchange factor #=GS D3ZN16/249-415 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS G7PQM1/248-402 AC G7PQM1 #=GS G7PQM1/248-402 OS Macaca fascicularis #=GS G7PQM1/248-402 DE Guanine nucleotide exchange factor-related protein #=GS G7PQM1/248-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A2K6RND2/248-402 AC A0A2K6RND2 #=GS A0A2K6RND2/248-402 OS Rhinopithecus roxellana #=GS A0A2K6RND2/248-402 DE Uncharacterized protein #=GS A0A2K6RND2/248-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus roxellana; #=GS H2NDZ6/248-401 AC H2NDZ6 #=GS H2NDZ6/248-401 OS Pongo abelii #=GS H2NDZ6/248-401 DE Secretion regulating guanine nucleotide exchange factor #=GS H2NDZ6/248-401 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Ponginae; Pongo; Pongo abelii; #=GS A0A2K6A8T6/250-402 AC A0A2K6A8T6 #=GS A0A2K6A8T6/250-402 OS Mandrillus leucophaeus #=GS A0A2K6A8T6/250-402 DE Uncharacterized protein #=GS A0A2K6A8T6/250-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Mandrillus; Mandrillus leucophaeus; #=GS A0A2K5K9C7/251-405 AC A0A2K5K9C7 #=GS A0A2K5K9C7/251-405 OS Colobus angolensis palliatus #=GS A0A2K5K9C7/251-405 DE Uncharacterized protein #=GS A0A2K5K9C7/251-405 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; #=GS H2Q387/249-402 AC H2Q387 #=GS H2Q387/249-402 OS Pan troglodytes #=GS H2Q387/249-402 DE SERGEF isoform 1 #=GS H2Q387/249-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A096NAM5/248-404 AC A0A096NAM5 #=GS A0A096NAM5/248-404 OS Papio anubis #=GS A0A096NAM5/248-404 DE Uncharacterized protein #=GS A0A096NAM5/248-404 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Papio; Papio anubis; #=GS A0A2K5N7Q1/249-403 AC A0A2K5N7Q1 #=GS A0A2K5N7Q1/249-403 OS Cercocebus atys #=GS A0A2K5N7Q1/249-403 DE Uncharacterized protein #=GS A0A2K5N7Q1/249-403 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Cercocebus; Cercocebus atys; #=GS A0A2K6KNU1/248-402 AC A0A2K6KNU1 #=GS A0A2K6KNU1/248-402 OS Rhinopithecus bieti #=GS A0A2K6KNU1/248-402 DE Uncharacterized protein #=GS A0A2K6KNU1/248-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus bieti; #=GS F7GWM5/249-402 AC F7GWM5 #=GS F7GWM5/249-402 OS Macaca mulatta #=GS F7GWM5/249-402 DE Guanine nucleotide exchange factor-related protein #=GS F7GWM5/249-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2K6E2P2/249-402 AC A0A2K6E2P2 #=GS A0A2K6E2P2/249-402 OS Macaca nemestrina #=GS A0A2K6E2P2/249-402 DE Uncharacterized protein #=GS A0A2K6E2P2/249-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca nemestrina; #=GS A0A2K5UB36/249-402 AC A0A2K5UB36 #=GS A0A2K5UB36/249-402 OS Macaca fascicularis #=GS A0A2K5UB36/249-402 DE Uncharacterized protein #=GS A0A2K5UB36/249-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A2I3MFU3/248-402 AC A0A2I3MFU3 #=GS A0A2I3MFU3/248-402 OS Papio anubis #=GS A0A2I3MFU3/248-402 DE Uncharacterized protein #=GS A0A2I3MFU3/248-402 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Papio; Papio anubis; #=GF SQ 18 Q9UGK8/251-404 ---LPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSG--LLVGCGAGHSLALCQLPA---------- Q80YD6/248-407 AVFLPLPQRIEAHYFQDEKVTAVWSGWTHLVAKTETGKVFTWGRADYGQLGRRLEPPEAQKPVEQDSSLAFQGPQNSVPSPLHCLTGATEISCGSEHNLAVIRDKCCSWGWNEHGMCGDGTESNVWTPTPVQALPPSPSRLLLVGCGAGHSLAVCQLPAH--------- H0X4B1/250-402 --FLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKMFTWGRADYGQLGRTLESHEGWKLEKQDSSLPCSRPQNSMPSSLHCLSGATEVSCGSEHNLAVIGGTCYSWGWNEHGMCGDGTEDNIWAPKPVQSLWSSLA--LLVGCGAGHSLALCHL------------ F6YFG6/256-407 ---LPVPQKIEANCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPLNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLLSSG--LLVGCGAGHSLALCQL------------ D3ZN16/249-415 -TFLPLPQRVEAHYFQDEKVTAVWSGWTHLVAKTETGKVFTWGRADYGQLGRTLGSPEAQKHGEQDSSLAFQRLQNSVPSPLHCLTGAAEVSCGSEHNLAVIRDKCCSWGWNEHGMCGDGTESNVWTPTPVQAL-PSPSRLLLVGCGAGHSLALCQLPAHPAPCQDLTV G7PQM1/248-402 AAFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDTFLPCSRLLNNMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A2K6RND2/248-402 AAFLPVPQKIEARCFQNEKVTAVWSGWTHLLAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLPNSVPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ H2NDZ6/248-401 -AFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSLSG--LLVGCGAGHSLALCQL------------ A0A2K6A8T6/250-402 --FLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A2K5K9C7/251-405 ---LPVPQKIEAHCFQNEKVTAVWSGWTHLLAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLPNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQLPAH--------- H2Q387/249-402 -AFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A096NAM5/248-404 AAFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTETNIWAPKPVQALLSSSG--LLVGCGAGHSLALCQLPA---------- A0A2K5N7Q1/249-403 -AFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFVPCSRLLNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQLP----------- A0A2K6KNU1/248-402 AAFLPVPQKIEARCFQNEKVTAVWSGWTHLLAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLPNSVPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ F7GWM5/249-402 -AFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNNMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A2K6E2P2/249-402 -AFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNNMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A2K5UB36/249-402 -AFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNNMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTEANIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ A0A2I3MFU3/248-402 AAFLPVPQKIEAHCFQNEKVTAVWSGWTHLVAQTETGKVFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRLLNSMPSSLHCLTGATEVSCGSEHNLAVIGGVCYSWGWNEHGMCGDGTETNIWAPKPVQALLSSSG--LLVGCGAGHSLALCQL------------ #=GC scorecons 0269969977997699699999899999997969999979999999999999597559659556998586657549769967999899798999999999896649699999999999999959796959998946855009999999999997989110000000000 #=GC scorecons_70 __**************************************************_**__**_*__****_**__*__***************************_*_*****************_*****_*****__*____****************____________ #=GC scorecons_80 ___**_*******_**_***************_*******************_**__*__*___***_*___*__**_**_*********************___*_***************_*_*_*_*****__*____****************____________ #=GC scorecons_90 ___**_**__**__**_*****_*******_*_*****_*************_*___*__*___***_*______*__**__******_*_***********___*_***************_*_*_*_*****__*____************_***____________ //