# STOCKHOLM 1.0
#=GF ID 2.130.10.30/FF/000029
#=GF DE Secretion-regulating guanine nucleotide exchange factor
#=GF AC 2.130.10.30/FF/000029
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 35.711
#=GS Q9UGK8/4-250      AC Q9UGK8
#=GS Q9UGK8/4-250      OS Homo sapiens
#=GS Q9UGK8/4-250      DE Secretion-regulating guanine nucleotide exchange factor
#=GS Q9UGK8/4-250      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS Q9UGK8/4-250      DR GO; GO:0005087; GO:0005515; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0016235; GO:0043231; GO:0050709; 
#=GS Q80YD6/2-247      AC Q80YD6
#=GS Q80YD6/2-247      OS Mus musculus
#=GS Q80YD6/2-247      DE Secretion-regulating guanine nucleotide exchange factor
#=GS Q80YD6/2-247      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; 
#=GS Q80YD6/2-247      DR GO; GO:0005087; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0016235; GO:0043231; GO:0050709; 
#=GS A0A1L1SUM5/4-248  AC A0A1L1SUM5
#=GS A0A1L1SUM5/4-248  OS Mus musculus
#=GS A0A1L1SUM5/4-248  DE Secretion-regulating guanine nucleotide exchange factor
#=GS A0A1L1SUM5/4-248  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; 
#=GS H0X4B1/6-249      AC H0X4B1
#=GS H0X4B1/6-249      OS Otolemur garnettii
#=GS H0X4B1/6-249      DE Uncharacterized protein
#=GS H0X4B1/6-249      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur; Otolemur garnettii; 
#=GS A0A2K5SF55/3-252  AC A0A2K5SF55
#=GS A0A2K5SF55/3-252  OS Cebus capucinus imitator
#=GS A0A2K5SF55/3-252  DE Uncharacterized protein
#=GS A0A2K5SF55/3-252  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Cebinae; Cebus; Cebus capucinus; Cebus capucinus imitator; 
#=GS G7PQM1/5-247      AC G7PQM1
#=GS G7PQM1/5-247      OS Macaca fascicularis
#=GS G7PQM1/5-247      DE Guanine nucleotide exchange factor-related protein
#=GS G7PQM1/5-247      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; 
#=GS A0A2K5EXZ6/4-254  AC A0A2K5EXZ6
#=GS A0A2K5EXZ6/4-254  OS Aotus nancymaae
#=GS A0A2K5EXZ6/4-254  DE Uncharacterized protein
#=GS A0A2K5EXZ6/4-254  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Aotidae; Aotus; Aotus nancymaae; 
#=GS D3ZN16/2-248      AC D3ZN16
#=GS D3ZN16/2-248      OS Rattus norvegicus
#=GS D3ZN16/2-248      DE Secretion-regulating guanine nucleotide exchange factor
#=GS D3ZN16/2-248      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; 
#=GS F6YFG6/4-255      AC F6YFG6
#=GS F6YFG6/4-255      OS Callithrix jacchus
#=GS F6YFG6/4-255      DE Secretion regulating guanine nucleotide exchange factor
#=GS F6YFG6/4-255      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; 
#=GS G1S7Q1/7-248      AC G1S7Q1
#=GS G1S7Q1/7-248      OS Nomascus leucogenys
#=GS G1S7Q1/7-248      DE Uncharacterized protein
#=GS G1S7Q1/7-248      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hylobatidae; Nomascus; Nomascus leucogenys; 
#=GS H2NDZ6/6-247      AC H2NDZ6
#=GS H2NDZ6/6-247      OS Pongo abelii
#=GS H2NDZ6/6-247      DE Secretion regulating guanine nucleotide exchange factor
#=GS H2NDZ6/6-247      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Ponginae; Pongo; Pongo abelii; 
#=GS A0A2K5K9C7/9-250  AC A0A2K5K9C7
#=GS A0A2K5K9C7/9-250  OS Colobus angolensis palliatus
#=GS A0A2K5K9C7/9-250  DE Uncharacterized protein
#=GS A0A2K5K9C7/9-250  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; 
#=GS A0A2K6A8T6/8-249  AC A0A2K6A8T6
#=GS A0A2K6A8T6/8-249  OS Mandrillus leucophaeus
#=GS A0A2K6A8T6/8-249  DE Uncharacterized protein
#=GS A0A2K6A8T6/8-249  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Mandrillus; Mandrillus leucophaeus; 
#=GS G3QEI0/4-247      AC G3QEI0
#=GS G3QEI0/4-247      OS Gorilla gorilla gorilla
#=GS G3QEI0/4-247      DE Secretion regulating guanine nucleotide exchange factor
#=GS G3QEI0/4-247      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Gorilla; Gorilla gorilla; Gorilla gorilla gorilla; 
#=GS H2Q387/7-248      AC H2Q387
#=GS H2Q387/7-248      OS Pan troglodytes
#=GS H2Q387/7-248      DE SERGEF isoform 1
#=GS H2Q387/7-248      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; 
#=GS A0A2I3MFU3/8-247  AC A0A2I3MFU3
#=GS A0A2I3MFU3/8-247  OS Papio anubis
#=GS A0A2I3MFU3/8-247  DE Uncharacterized protein
#=GS A0A2I3MFU3/8-247  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Papio; Papio anubis; 
#=GS F7GWM5/8-248      AC F7GWM5
#=GS F7GWM5/8-248      OS Macaca mulatta
#=GS F7GWM5/8-248      DE Guanine nucleotide exchange factor-related protein
#=GS F7GWM5/8-248      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; 
#=GS A0A2K6E2P2/8-248  AC A0A2K6E2P2
#=GS A0A2K6E2P2/8-248  OS Macaca nemestrina
#=GS A0A2K6E2P2/8-248  DE Uncharacterized protein
#=GS A0A2K6E2P2/8-248  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca nemestrina; 
#=GS A0A2K5UB36/8-248  AC A0A2K5UB36
#=GS A0A2K5UB36/8-248  OS Macaca fascicularis
#=GS A0A2K5UB36/8-248  DE Uncharacterized protein
#=GS A0A2K5UB36/8-248  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; 
#=GF SQ 19
Q9UGK8/4-250              ------EPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAF
Q80YD6/2-247              ----ARESCASETVSAAAVLFAWGANSYGQLGLGHKEDVFLPQQLSDFCQAGCIKSVTGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEEVLRFTICKPLRGCPIRQVACGWDFTIMLTEKGQVLSCGSNAFGQLGVPHGPRKCVVPQAIECLREKVVCVAAGLRHALATTATGSVFQWGTGLASSGRRLCPGQNLPLFLTAKEPSRVTGLENSTAVCAVAGSDHSASLTDTGELYVWGRNKHGQLASR---
A0A1L1SUM5/4-248          ------ESCASETVSAAAVLFAWGANSYGQLGLGHKEDVFLPQQLSDFCQAGCIKSVTGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEEVLRFTICKPLRGCPIRQVACGWDFTIMLTEKGQVLSCGSNAFGQLGVPHGPRKCVVPQAIECLREKVVCVAAGLRHALATTATGSVFQWGTGLASSGRRLCPGQNLPLFLTAKEPSRVTGLENSTAVCAVAGSDHSASLTDTGELYVWGRNKHGQLASRA--
H0X4B1/6-249              --------RASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRCVRRITGGGGHSAIVTDGGGLFVCGLNKDGQLGLGHTDDVLYFTPCKSLLGCAIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELLREKVVCIAAGLRHALAATVSGIVFQWGTGLASSGRRLCPGNALPLFLTAKEPSRVTGLENCKAVCVVAGSDHSASLTDAGEVYVWGSNKHGQLATQAA-
A0A2K5SF55/3-252          RPRMEREPSASEAAPVAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRCIRRITGGGGHSAIVTDEGDLFVCGLNKDGQLGLGHTEDVPYFTPCKSLLGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGAPHGPRRCVVPQAIELHEEKIVCIAAGLRHALAATVSGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVIAGSDHSASLTDAGEVYVWGSNKHGQLATE---
G7PQM1/5-247              -------PSASEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDIGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGLRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATE---
A0A2K5EXZ6/4-254          -PRMEREPSASEAAPVAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRCIRRITGGGGHSAIVTDGGDLFVCGLNKDGQLGLGHTEDVPYFTPCKSLLGCPIQQVACGWDFTIILTENSQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKIVCIAAGLRHALAATVSGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVIAGSDHSASLTDAGEVYVWGSNKHGQLATKAA-
D3ZN16/2-248              ----ARESCASEAVSAAAVLFAWGANSYGQLGLGHKEDVLLPQQLSDFCKSGCIKSVTGGGGHSVVVTDGGGLFVCGLNKDGQLGLGHTEEVLRFTICKPLLGCPIRQVACGWDFTIMLTEKGQVLSCGSNAFGQLGVPHGPRKCVVPQAIECLREKVVCVAAGLRHALATTDTGSTFQWGTGLASSGRRLCPGQNLPLFLTAKEPSRVTGLESSTVVCAVAGSDHSASLTDTGELYVWGRNKHGQLASLA--
F6YFG6/4-255              -PRMEREPSASEAAPVAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKSRCIRRITGGGGHSAIVTDGGDLFVCGLNKDGQLGLGHTEDVPYFTPCQSLFGCPIQQVACGWDFTIILTENGQILSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKIVCIAAGLRHALAATVSGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVIAGSDHSASLTDAGEVYVWGSNKHRQLATQAAF
G1S7Q1/7-248              ---------ASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIVLTKNGQVLSCGSNYFGQLGVPHGPQRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCRGQSLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEA--
H2NDZ6/6-247              --------SASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSIRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEEIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVC-AAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLAAEA--
A0A2K5K9C7/9-250          -----------EAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEAAF
A0A2K6A8T6/8-249          ----------SEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDVGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEAA-
G3QEI0/4-247              ------EPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE---
H2Q387/7-248              ---------ASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIEFHKEKVVCIAAGLRHALAATASGIVFQWGTGLAPCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEA--
A0A2I3MFU3/8-247          ----------SEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLKDFCKPRSVRRITGGGGHSAVVTDVGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGADHSASLTDAGEVYVWGSNKHGQLATE---
F7GWM5/8-248              ----------SEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDIGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEA--
A0A2K6E2P2/8-248          ----------SEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDIGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEA--
A0A2K5UB36/8-248          ----------SEAAPAAAVLFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDIGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIILTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHALAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLATEA--
#=GC scorecons            0000012125897667996999999999999999999997999996999766677679999999779995979999999999999999987765995986949989699999999996998689899999969999989998879999999955699799699999998969569679999999986999998985999969999999999997867696599899999999699699996999899954400
#=GC scorecons_70         __________********_*******************************_*_**_*************_**********************__**_****_*****************************_********************__******************_**_*******************_*******************_****_*******************_*******_____
#=GC scorecons_80         __________***__***_**************************_****____*_*************_*********************___**_**_*_****_**********_***_*********_********************___*****_*********_*__*_**********_********_****_**************_*_*__***********_**_****_*******_____
#=GC scorecons_90         __________**____**_********************_*****_***________*******__***_*_******************____**_**_*_****_**********_***_*********_***********_********___**_**_*********_*__*__*********_********_****_************_*___*__***********_**_****_*******_____
//