# STOCKHOLM 1.0 #=GF ID 2.130.10.10/FF/000910 #=GF DE Diphthamide biosynthesis 7 #=GF AC 2.130.10.10/FF/000910 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 76.483 #=GS Q9BTV6/6-347 AC Q9BTV6 #=GS Q9BTV6/6-347 OS Homo sapiens #=GS Q9BTV6/6-347 DE Diphthine methyltransferase #=GS Q9BTV6/6-347 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q9BTV6/6-347 DR GO; GO:0005515; GO:0017183; #=GS Q9BTV6/6-347 DR EC; 3.1.1.97; #=GS Q9CYU6/7-349 AC Q9CYU6 #=GS Q9CYU6/7-349 OS Mus musculus #=GS Q9CYU6/7-349 DE Diphthine methyltransferase #=GS Q9CYU6/7-349 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q9CYU6/7-349 DR GO; GO:0017183; #=GS Q9CYU6/7-349 DR EC; 3.1.1.97; #=GS Q9W3X3/1-355 AC Q9W3X3 #=GS Q9W3X3/1-355 OS Drosophila melanogaster #=GS Q9W3X3/1-355 DE GH14157p #=GS Q9W3X3/1-355 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9W3X3/1-355 DR GO; GO:0005737; GO:0017183; GO:0032451; #=GS Q9FM51/9-332 AC Q9FM51 #=GS Q9FM51/9-332 OS Arabidopsis thaliana #=GS Q9FM51/9-332 DE Transducin/WD40 repeat-like superfamily protein #=GS Q9FM51/9-332 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Brassicales; Brassicaceae; Camelineae; Arabidopsis; Arabidopsis thaliana; #=GS Q9FM51/9-332 DR GO; GO:0080008; #=GS U3EMV2/6-345 AC U3EMV2 #=GS U3EMV2/6-345 OS Callithrix jacchus #=GS U3EMV2/6-345 DE Diphthamide biosynthesis 7 #=GS U3EMV2/6-345 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS D4A1S8/10-347 AC D4A1S8 #=GS D4A1S8/10-347 OS Rattus norvegicus #=GS D4A1S8/10-347 DE Diphthamide biosynthesis 7 #=GS D4A1S8/10-347 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS D4A1S8/10-347 DR GO; GO:0017183; #=GS A0A2K5TZ42/6-346 AC A0A2K5TZ42 #=GS A0A2K5TZ42/6-346 OS Macaca fascicularis #=GS A0A2K5TZ42/6-346 DE Uncharacterized protein #=GS A0A2K5TZ42/6-346 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A2K6K3B0/64-412 AC A0A2K6K3B0 #=GS A0A2K6K3B0/64-412 OS Rhinopithecus bieti #=GS A0A2K6K3B0/64-412 DE Uncharacterized protein #=GS A0A2K6K3B0/64-412 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus bieti; #=GS G3QU58/6-345 AC G3QU58 #=GS G3QU58/6-345 OS Gorilla gorilla gorilla #=GS G3QU58/6-345 DE Diphthamide biosynthesis 7 #=GS G3QU58/6-345 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Gorilla; Gorilla gorilla; Gorilla gorilla gorilla; #=GS A0A2R9AU22/64-405 AC A0A2R9AU22 #=GS A0A2R9AU22/64-405 OS Pan paniscus #=GS A0A2R9AU22/64-405 DE Uncharacterized protein #=GS A0A2R9AU22/64-405 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A2K6PVQ2/64-412 AC A0A2K6PVQ2 #=GS A0A2K6PVQ2/64-412 OS Rhinopithecus roxellana #=GS A0A2K6PVQ2/64-412 DE Uncharacterized protein #=GS A0A2K6PVQ2/64-412 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus roxellana; #=GS H2QY86/6-347 AC H2QY86 #=GS H2QY86/6-347 OS Pan troglodytes #=GS H2QY86/6-347 DE Diphthamide biosynthesis 7 #=GS H2QY86/6-347 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS F7B834/6-347 AC F7B834 #=GS F7B834/6-347 OS Macaca mulatta #=GS F7B834/6-347 DE Uncharacterized protein #=GS F7B834/6-347 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2R9AY04/9-350 AC A0A2R9AY04 #=GS A0A2R9AY04/9-350 OS Pan paniscus #=GS A0A2R9AY04/9-350 DE Uncharacterized protein #=GS A0A2R9AY04/9-350 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GF SQ 14 Q9BTV6/6-347 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQVRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRS-------------------------- Q9CYU6/7-349 GTLRVLQAVDTELTADSVEWCPV-EGYQHLLACGTYQLRAPRDQPAL-------DGSEPQVRLGRLYLFSFSEHNTAKPLLEVQRRDSSAVLDMKW-CHIPVSGHVLLGLANASGSIGLL------RLMEC-ENNSYTLQPISSLALDENCLSLSMDWSTGKSVRAREQPLKIISSDSKGQLHLLMVNEGTAELQLVASWPAHHFEAWIAAFNYWQTELVYSGGDDCLLRGWDTR---MLGTPVFTSKRHCMGVCSIQSSPHQEHILATGSYDEHVLLWDTRNIRQPLADVPVQ--GGVWRLKWHPVHHHLLLAACMHNGFKILNCQKAIEEKQDITVLTSHEMPNSLVYGADWSW-LFHSMKPT---------------------- Q9W3X3/1-355 -MFTTLHSEDTEYSADSVEWLTHDDAATGFFACGTYQLVQEEDEPAA-------ETSAKRPRKGRVYLYQFEEENCR--LERLQCIETSAILDMKWLPAWSSECNPHLATVNSLGQMELYEFLQDAKLLQR-RTC-FSLAEQDSS--EEAPLALALDW------QHDGQHIRLAISDSKGGLNLLSYS-SQGEIIRERSWLSHGFEAWTCAFDRWSPHILYSGGDDMLLMAHDLR---TKQR-AWTNRAHMAGVTCLLSHPRHENHLLTGSYDEQLRLFDTRSMKRSLAELDLS--GGIWRLKPHPAQPDLILAACMYTNFSVVQLDVAA---PGLSLLGAYEEHKSICYGADWA--PWRNKDDASLTMATCSFYDHTLCVSRVDIN Q9FM51/9-332 -----------EGNADAVEFCPH-ESYANLLAASTYTLQE-GDCPS---------------RSGSVYLFDVGDVEDV-GLNLIQKIDTAGVFDIRW-SRGGDGGDVALAQADADGCLIVY------KIDET-ESK-GTLREVSGKRISSS-MCLCLDWDPSST--------SIVVGLSDGSASVVSFT--DSNLETVQEWKGHDFELWTASFDLNNPNLVYTGSDDCKFSCWDIRDSPADNRVFQNSKVHTMGVCCISSNPSDPYSIFTGSYDETLRVWDTRSVSRPLNETSVSLGGGVWRIKHHPSLSGVVLAACMHNGFALAKVSDGKGE-----VLESYNKHHSLAYGADW----YRGKDQKQSVVATCSFYDRLLRVW----- U3EMV2/6-345 ----ALQTVDTELTADAVEWCPL-RGLRHLLACGTYQLRR-ADEPADPQSK---EVEEPQIRLGRLFLYSFNENKSTHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLAES-EKSGHMLEPLSSLALEQHCLALSLDWSTGKTGRTRDQPLKIISSDSIGQLHLLMVNETGSRLQKVASWQAHQFEAWIAAFNYWHTEIVYSGGDDGLLRGWDTR---APGRFLFTSMRHSMGVCSIQSSPHREHVLATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEKKQEATVLASHTLPNSLVYGADWSWLLFHSL------------------------- D4A1S8/10-347 ---RALQAVDTELTADSVEWCPV-EGCQHLLACGTYQLRAPKDQPAP-------DGSEPQVRLGRLYLFSFSEDNTAKPLLEVQRRDSSAVLDMKW-CHIPVSGHVLLGLANASGSVELL------RLMEC-EKNSYTLQLISSLALDESCLSLSLDWSTGKSVRAREQPLKIISSDSKGQLHLLLLSEGAAQLQLLASWPAHHFEAWIAAFNYWQTELVYSGGDDCLLRGWDTR---MLGKPVFTSKRHSMGVCSIQSSPHREHILATGSYDEHVLLWDTRNVRQPLADVPVQ--GGVWRLRWHPVHHHLLLAACMHNGFKILNCQKAIEEKQDITVLTSHTMPNSLVYGADWSWLLFHSV------------------------- A0A2K5TZ42/6-346 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDPPADPQSKGRMEVEEPRVRLGRLYLYNFNENKSTQPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRARDQPLKIISSDSTGQLHLLTVNETGPKLQKVAAWQAHQFEAWIAAFDYWHTEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHWEHVLATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAVEEKQEATVLASHTLPNSLVYGADWSWLRFR--------------------------- A0A2K6K3B0/64-412 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDPPADPQSKGGMEVEEPRVRLGRLFLYSFSENNSTHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVESEEKS-HVLEPLSGLALEEQCLALSLDWSTGNTGRARDQPLKIISSDSTGQLHLLMVNETGPRLQKVASWQAHQFEAWIAAFDYWHTEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHWEHVLATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEEKQEATVLASHTLPDSLVYGADWSWLLFRSLQWAPS-------------------- G3QU58/6-345 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQVRLGRLFLYSFNDNSSIHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHTEIVYSGGDDGLLRGWDTR---VPGQFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEEMQEATVLTSHTLPDSLVYGADWSWLLF---------------------------- A0A2R9AU22/64-405 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQVRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHTEIVYSGGDDGLLRGWDTR---VPSKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRS-------------------------- A0A2K6PVQ2/64-412 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDPPADPQSKGGMEVEEPRVRLGRLFLYSFNENNSTHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVESEEKS-HVLEPLSSLALEEQCLALSLDWSTGNTGRARDQPLKIISSDSTGQLHLLMVNETGPRLQKVASWQAHQFEAWIAAFDYWHTEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHWEHVLATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEEKQEATVLASHTLPDSLVYGADWSWLLFRSLQWAPS-------------------- H2QY86/6-347 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQVRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHTEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRS-------------------------- F7B834/6-347 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDPPADPQSKGRMEVEEPRVRLGRLYLYNFNENKSTQPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRARDQPLKIISSDSTGQLHLLMVNETGPKLQKVASWQAHQFEAWIAAFDYWHTEIVYSGGDDGLLRGWDTR---VPGKFLFTSKRHTMGVCSIQSSPHWEHVLATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAVEEKQEATVLASHTLPNSLVYGADWSWLRFRS-------------------------- A0A2R9AY04/9-350 ----ALQTVDTELTADSVEWCPL-QGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQVRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKW-CHIPVAGHALLGLADASGSIQLL------RLVES-EKS-HVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHTEIVYSGGDDGLLRGWDTR---VPSKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQ--GGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRS-------------------------- #=GC scorecons 000045434559459969966740554457796799695435939722212111532444494966797464745432493469547777779779055454465549647674956475000000774740744044944476444564475958994443424333544576576949565774453334475465694594996966796464656797979946745695900043453447774956996674959536647499999955476999665679675575009979968499355576999997579565545473452433479477535497599999432366411000000000000000000000000 #=GC scorecons_70 ___________*__********_______*********____*_**_______________*_******_*_*______*__**__**********_______*___*__***_*___*_______**_*__*_____*___**____*__*_*_***______________*__*_*_*_*_**________*____**__*_****_****_____********_**__**_*__________***_*_****_*_*_*__*__*_******___*****_*_*****__*___*******_**____*_******_**_*_____*________**_**____**_*****_____*___________________________ #=GC scorecons_80 ___________*__**_**__*_______***__**_*____*_*________________*_*__***__________*___*__**___*****___________*__*_*_*___*________*_*________*____________*_*_***______________*____*_*___**________*_____*__*_**_*___*_______**_*_**__*___*_*___________*__*__**__*_*_*_____*_******___*_***____**____*___*****_*_**____*_******__*________________**_*_____**_*****_________________________________ #=GC scorecons_90 ___________*__**_**____________*__**_*____*_*________________*_*___*___________*___*________*__*___________*______*_______________________*______________*_***___________________*_*___________________*__*_**_*___*________*_*_**______*_*______________*__**____*_*_______******_____***_____*________**_**_*_**______*****___*_________________*_______*__*****_________________________________ //