# STOCKHOLM 1.0 #=GF ID 2.130.10.10/FF/000802 #=GF DE Sortilin #=GF AC 2.130.10.10/FF/000802 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 56.716 #=GS B0R052/109-263_296-466 AC B0R052 #=GS B0R052/109-263_296-466 OS Danio rerio #=GS B0R052/109-263_296-466 DE Sortilin #=GS B0R052/109-263_296-466 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS B0R052/109-263_296-466 DR GO; GO:0071466; #=GS E1BKZ9/179-523 AC E1BKZ9 #=GS E1BKZ9/179-523 OS Bos taurus #=GS E1BKZ9/179-523 DE Sortilin #=GS E1BKZ9/179-523 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS E1BKZ9/179-523 DR GO; GO:0032596; #=GS A0A1L8H727/143-452 AC A0A1L8H727 #=GS A0A1L8H727/143-452 OS Xenopus laevis #=GS A0A1L8H727/143-452 DE Sortilin #=GS A0A1L8H727/143-452 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis; #=GS A0A2K6KBT5/39-381 AC A0A2K6KBT5 #=GS A0A2K6KBT5/39-381 OS Rhinopithecus bieti #=GS A0A2K6KBT5/39-381 DE Sortilin #=GS A0A2K6KBT5/39-381 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus bieti; #=GS F1S5Z7/233-581 AC F1S5Z7 #=GS F1S5Z7/233-581 OS Sus scrofa #=GS F1S5Z7/233-581 DE Sortilin #=GS F1S5Z7/233-581 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS A0A3Q7SAV8/5-348 AC A0A3Q7SAV8 #=GS A0A3Q7SAV8/5-348 OS Vulpes vulpes #=GS A0A3Q7SAV8/5-348 DE Sortilin #=GS A0A3Q7SAV8/5-348 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes; Vulpes vulpes; #=GS A0A1S3A4U7/5-349 AC A0A1S3A4U7 #=GS A0A1S3A4U7/5-349 OS Erinaceus europaeus #=GS A0A1S3A4U7/5-349 DE Sortilin #=GS A0A1S3A4U7/5-349 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae; Erinaceus; Erinaceus europaeus; #=GS I3MGW4/70-427 AC I3MGW4 #=GS I3MGW4/70-427 OS Ictidomys tridecemlineatus #=GS I3MGW4/70-427 DE Sortilin #=GS I3MGW4/70-427 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys; Ictidomys tridecemlineatus; #=GS A0A2K6F499/141-486 AC A0A2K6F499 #=GS A0A2K6F499/141-486 OS Propithecus coquereli #=GS A0A2K6F499/141-486 DE Sortilin #=GS A0A2K6F499/141-486 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus; Propithecus coquereli; #=GS M3WM95/167-520 AC M3WM95 #=GS M3WM95/167-520 OS Felis catus #=GS M3WM95/167-520 DE Sortilin #=GS M3WM95/167-520 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus; #=GS A0A452UBF4/23-366 AC A0A452UBF4 #=GS A0A452UBF4/23-366 OS Ursus maritimus #=GS A0A452UBF4/23-366 DE Sortilin #=GS A0A452UBF4/23-366 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus maritimus; #=GS A0A452S898/76-416 AC A0A452S898 #=GS A0A452S898/76-416 OS Ursus americanus #=GS A0A452S898/76-416 DE Sortilin #=GS A0A452S898/76-416 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; #=GS F7ACW9/63-365 AC F7ACW9 #=GS F7ACW9/63-365 OS Xenopus tropicalis #=GS F7ACW9/63-365 DE Sortilin #=GS F7ACW9/63-365 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS A0A2K6NWF3/4-345 AC A0A2K6NWF3 #=GS A0A2K6NWF3/4-345 OS Rhinopithecus roxellana #=GS A0A2K6NWF3/4-345 DE Sortilin #=GS A0A2K6NWF3/4-345 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus roxellana; #=GS A5PMG8/106-263_296-466 AC A5PMG8 #=GS A5PMG8/106-263_296-466 OS Danio rerio #=GS A5PMG8/106-263_296-466 DE Sortilin #=GS A5PMG8/106-263_296-466 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS A5PMG8/106-263_296-466 DR GO; GO:0071466; #=GS B1H1Q9/143-452 AC B1H1Q9 #=GS B1H1Q9/143-452 OS Xenopus laevis #=GS B1H1Q9/143-452 DE Sortilin #=GS B1H1Q9/143-452 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis; #=GS A0A452S891/109-451 AC A0A452S891 #=GS A0A452S891/109-451 OS Ursus americanus #=GS A0A452S891/109-451 DE Sortilin #=GS A0A452S891/109-451 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; #=GF SQ 17 B0R052/109-263_296-466 ---TGVVLALTTFQMPLVFLRFGQSKLYRSENYGKSFEDVSELINNTFINTDFGIAIGPENSGKVILTGDASGGS-GARIFRSRDFGKSFVHTELPFHPLMQIMYNPQTTDVLAAISTKHDLWISKDFGTTWTKIHEMVCVVKWGI-DALFFSTNLNGSC----------------------------------RFLFASVMAASGNIIPSASEEIMRAIHVSVDLGETWNMAQLPPVSHEQFYSILAANDEMVFMHVDEPGDTGIGTIYVSDDRGTVYSKSLERHLY--TGGETDFTNVTSLRGVYTTSVLAEDNSVQTVITFDQGGEWVPLKKPENTKCDSTAKDAEMCSLHIHASYSTSMKVNV---------------- E1BKZ9/179-523 ----------------LVIMTFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSENIIFFTTYVNGSC-KADLGALELRRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYMTSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAP------------ A0A1L8H727/143-452 ---------------------------------------------------EFGMAIGPDNSGKVILVADVSGGSNGGRIFRSSDSAQTFVQTDLLFHPLISVLYSPENSNFLLVLSVDFNLWISKDFGETWKEIHHSVCSAKWAAGSTIIFTIDGNNSC-KADFRLMTLKRTSDFGQTFQVLRDRVHSFGLWGRFLLASVV---------ELDGLNRKIHVSQNQGDKWNVAQLPSVTYEQFYSVLAANDDMVFIHVDDEGDTGCGTIYTSDDRGILYSKSLERHLYTTTSGETDFTNVTSLHGVFITSVLSEDNSIHSVISFDQGGEWSPLRKPENSQCDSTAKDKEQCSLHIHAQYSISQRLPVPMPP------------ A0A2K6KBT5/39-381 -----------------------QSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSQNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSC-KADLGALELWRTLDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPN------- F1S5Z7/233-581 ------------------------SKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFIQTNLPFHPLTQMMYSPQNSDHLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSDSTIFFTTYVNGSC-KADLGALELRRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYMTSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPNAVGIVIA A0A3Q7SAV8/5-348 -----------------------QSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQSNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKDFGGKWEEIHKAVCLAKWGSENTIFFTTYANGSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGYGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPKA------ A0A1S3A4U7/5-349 -----------------------QSKLYRSEDYGKTFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSPGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPENSDYLLALSTENGLWVSRNFGGKWEEIHKAVCLAKWGPKSIIFFTTHVNGSC--TDLGTLELWRTSDLGKTFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDHGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKRLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPVAPLSEPNAVG---- I3MGW4/70-427 ---------------PLVIITSEQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPNNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSENTIFFTTYANVSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSTLSEDNSIQTMITFDQGGRWKHLRKPENSQCDATAKNKKECSLHIHASYSISQKLNVPMAPLSEANAVGIVIA A0A2K6F499/141-486 -----------------------QSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSSGGRIFRSSDFAKNFVQTDLPFHLLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSENIIFFTTYVNGSC-KADLGALELRRTSDLGKTFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWGMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPNAVG---- M3WM95/167-520 ---TGIILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKDFGGKWEEIHKAVCLAKWGSENTIFFTTYANGSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNV---------------- A0A452UBF4/23-366 -----------------------QSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKDFGGKWEEIHKAVCLAKWGSENTIFFTTYANGSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATARNKNECSLHIHASYSISQKLNVPMAPLSEPKA------ A0A452S898/76-416 ----------------------GQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKDFGGKWEEIHKAVCLAKWGSENTIFFTTYANGSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATARNKNECSLHIHASYSISQKLNVPMAPLS---------- F7ACW9/63-365 ---------------------------------------------------EFGMAIGPDNSGKVILVADVSGGSKGGRIFRSSDSAQIFVQTDLLFHPLVSVSYSTENSNFLLVLSVDFGLWISRDFGETWKEIHQSVCSAKWAAGNTIHFTTARNNSCTEADFRLMTLKRTSDFGQTFRVLKERVHSFGLWGRFLLASVV---------ELDGLKRKIHVSQNQGNTWNVAQLPAVTYEQFYSVLAATDDMVFIHVDDEGDTGCGTIYTSDDRGILYSKSLERHLYTTTGGETDFTNVTSLHGVFITSVLSEDNSIHSVITFDQGGEWSPLRKPENAQCDSTAKDKEQCSLHIHAQYSISQ-------------------- A0A2K6NWF3/4-345 ----------------------GQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSQNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSC-KADLGALELWRTLDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSE--------- A5PMG8/106-263_296-466 GDGTGVVLALTTFQMPLVFLRFGQSKLYRSENYGKSFEDVSELINNTFINTDFGIAIGPENSGKVILTGDASGGS-GARIFRSRDFGKSFVHTELPFHPLMQIMYNPQTTDVLAAISTKHDLWISKDFGTTWTKIHEMVCVVKWGI-DALFFSTNLNGSC----------------------------------RFLFASVMAASGNIIPSASEEIMRAIHVSVDLGETWNMAQLPPVSHEQFYSILAANDDMVFMHVDEPGDTGIGTIYVSDDRGTVYSKSLERHLY--TGGETDFTNVTSLRGVYTTSVLAEDNSVQTVITFDQGGEWVPLKKPENTKCDSTAKDAEMCSLHIHASYSTSMKVNV---------------- B1H1Q9/143-452 ---------------------------------------------------EFGMAIGPDNSGKVILVADVSGGSNGGRIFRSSDSAQTFVQTDLLFHPLISVLYSPENSNFLLVLSVDFNLWISKDFGETWKEIHHSVCSAKWAAGSTIIFTIDGNNSC-KADFRLMTLKRTSDFGQTFQVLRDRVHSFGLWGRFLLASVV---------ELDGLNRKIHVSQNQGDKWNVAQLPSVTYEQFYSVLAANDDMVFIHVDDEGDTGCGTIYTSDDRGILYSKSLERHLYTTTSGETDFTNVTSLHGVFITSVLSEDNSIHSVISFDQGGEWSPLRKPENSQCDSTAKDKEQCSLHIHAQYSISQRLPVPMPP------------ A0A452S891/109-451 ----------------LVIMTFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSHGGRIFRSSDFAKNFVQTNLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKDFGGKWEEIHKAVCLAKWGSENTIFFTTYANGSC-KADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVM---------ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWKHLRKPENSECDATARNKNECSLHIHASYSISQKLNVPM-------------- #=GC scorecons 00000000000000001100001444444443444343433344444443479979999799999896777999929799999695764987859699895666978677659667965459979769955947995499479964356769774395990455433435255454543533433444555535999699960000000006455549599994669669569999695599999799989899979997599994999769999976999997999955979999999999969976998979999776697999995945979999659969986654999999969979665573323110000000000 #=GC scorecons_70 ___________________________________________________************************_*********_**_****_******___********_******___********__*_***__**_****____*_***__*_**__________________________________********_______________*_****_*_****_*****_*__********************_****_**********************__**************************************_*__******__**_*****__*******_******__*________________ #=GC scorecons_80 ___________________________________________________****************____****_*_*****_*____****_*_****____*_*_____*__**____**_**_**__*__**__**__**_____*_*_*__*_**__________________________________***_***________________*_****___*__*__****_*__********************_****_****_*****__*****_****__*************_***_****_******__*******_*__******__**_***____*******_**_*____*________________ #=GC scorecons_90 ____________________________________________________**_****_*******____****_*_*****_*____**_*_*_****____*_______*___*____**_*__**__*__**__**__**_______*____*_**__________________________________***_***________________*_****___*__*__****_*__*****_***_*****_***__****_***__*****__*****_****__*_***********_**__****_****____*_*****_*__*_****__**_***____*******_**_*_____________________ //