# STOCKHOLM 1.0 #=GF ID 1.25.40.180/FF/000057 #=GF DE Initiation Factor 4G (eIF4G) family #=GF AC 1.25.40.180/FF/000057 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 88.146 #=GS Q21531/518-762 AC Q21531 #=GS Q21531/518-762 OS Caenorhabditis elegans #=GS Q21531/518-762 DE Initiation Factor 4G (eIF4G) family #=GS Q21531/518-762 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q21531/518-762 DR GO; GO:0005829; GO:0016281; #=GS H0YCH5/78-323 AC H0YCH5 #=GS H0YCH5/78-323 OS Homo sapiens #=GS H0YCH5/78-323 DE Eukaryotic translation initiation factor 4 gamma 2 #=GS H0YCH5/78-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS H0YCH5/78-323 DR GO; GO:0005829; #=GS B5BM23/404-648 AC B5BM23 #=GS B5BM23/404-648 OS Caenorhabditis elegans #=GS B5BM23/404-648 DE Initiation Factor 4G (eIF4G) family #=GS B5BM23/404-648 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS B5BM23/404-648 DR GO; GO:0005829; GO:0016281; #=GS B5BM24/521-765 AC B5BM24 #=GS B5BM24/521-765 OS Caenorhabditis elegans #=GS B5BM24/521-765 DE Initiation Factor 4G (eIF4G) family #=GS B5BM24/521-765 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS B5BM24/521-765 DR GO; GO:0005829; GO:0016281; #=GS Q7JMF0/517-761 AC Q7JMF0 #=GS Q7JMF0/517-761 OS Caenorhabditis elegans #=GS Q7JMF0/517-761 DE Initiation Factor 4G (eIF4G) family #=GS Q7JMF0/517-761 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q7JMF0/517-761 DR GO; GO:0005829; GO:0016281; #=GS A0A486WX07/522-766 AC A0A486WX07 #=GS A0A486WX07/522-766 OS Caenorhabditis elegans #=GS A0A486WX07/522-766 DE Initiation Factor 4G (eIF4G) family #=GS A0A486WX07/522-766 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A8IQZ3/14-259 AC A8IQZ3 #=GS A8IQZ3/14-259 OS Chlamydomonas reinhardtii #=GS A8IQZ3/14-259 DE Predicted protein #=GS A8IQZ3/14-259 DR ORG; Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas; Chlamydomonas reinhardtii; #=GS A9SMV0/41-277 AC A9SMV0 #=GS A9SMV0/41-277 OS Physcomitrella patens #=GS A9SMV0/41-277 DE Predicted protein #=GS A9SMV0/41-277 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella; Physcomitrella patens; #=GS F6SP01/97-342 AC F6SP01 #=GS F6SP01/97-342 OS Ornithorhynchus anatinus #=GS F6SP01/97-342 DE Eukaryotic translation initiation factor 4 gamma 2 #=GS F6SP01/97-342 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS H3G0K7/291-504_542-575 AC H3G0K7 #=GS H3G0K7/291-504_542-575 OS Pristionchus pacificus #=GS H3G0K7/291-504_542-575 DE Uncharacterized protein #=GS H3G0K7/291-504_542-575 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A0A2G5UXM8/557-808 AC A0A2G5UXM8 #=GS A0A2G5UXM8/557-808 OS Caenorhabditis nigoni #=GS A0A2G5UXM8/557-808 DE Uncharacterized protein #=GS A0A2G5UXM8/557-808 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A8WN87/512-763 AC A8WN87 #=GS A8WN87/512-763 OS Caenorhabditis briggsae #=GS A8WN87/512-763 DE Protein CBR-IFG-1 #=GS A8WN87/512-763 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS A0A2J8UPW8/78-323 AC A0A2J8UPW8 #=GS A0A2J8UPW8/78-323 OS Pongo abelii #=GS A0A2J8UPW8/78-323 DE EIF4G2 isoform 14 #=GS A0A2J8UPW8/78-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Ponginae; Pongo; Pongo abelii; #=GS A0A2J8P5I5/78-323 AC A0A2J8P5I5 #=GS A0A2J8P5I5/78-323 OS Pan troglodytes #=GS A0A2J8P5I5/78-323 DE EIF4G2 isoform 14 #=GS A0A2J8P5I5/78-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2A6B877/795-1008_1046-1079 AC A0A2A6B877 #=GS A0A2A6B877/795-1008_1046-1079 OS Pristionchus pacificus #=GS A0A2A6B877/795-1008_1046-1079 DE Ifg-1 #=GS A0A2A6B877/795-1008_1046-1079 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A0A2G5UXY1/542-793 AC A0A2G5UXY1 #=GS A0A2G5UXY1/542-793 OS Caenorhabditis nigoni #=GS A0A2G5UXY1/542-793 DE Uncharacterized protein #=GS A0A2G5UXY1/542-793 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A2G5UXN7/564-815 AC A0A2G5UXN7 #=GS A0A2G5UXN7/564-815 OS Caenorhabditis nigoni #=GS A0A2G5UXN7/564-815 DE Uncharacterized protein #=GS A0A2G5UXN7/564-815 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A8WN89/341-592 AC A8WN89 #=GS A8WN89/341-592 OS Caenorhabditis briggsae #=GS A8WN89/341-592 DE Protein CBG00712 #=GS A8WN89/341-592 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GF SQ 18 Q21531/518-762 -----------CKKVRSLMNKVTPTSQRPLTEEFISYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELSQT----------GGKSAFRNKVLTRTQMTFQDKK--DIDADKLAI---IEKEEDPVK---KELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKIVQTCTFELFNSI-------KDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLEAAK--PYCSNKIRFMIMNLMELRKDKWIPRKST-ESGPKKI H0YCH5/78-323 -----------FRKVRGILNKLTPEKFDKLCLELLNVGVESKLI-LKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKREN---------PLL---PEEE--EQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKK-------KRVQL--KDM-GEDLECLCQIMRTVGPRLDHER--AKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTI B5BM23/404-648 -----------CKKVRSLMNKVTPTSQRPLTEEFISYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELSQT----------GGKSAFRNKVLTRTQMTFQDKK--DIDADKLAI---IEKEEDPVK---KELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKIVQTCTFELFNSI-------KDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLEAAK--PYCSNKIRFMIMNLMELRKDKWIPRKST-ESGPKKI B5BM24/521-765 -----------CKKVRSLMNKVTPTSQRPLTEEFISYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELSQT----------GGKSAFRNKVLTRTQMTFQDKK--DIDADKLAI---IEKEEDPVK---KELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKIVQTCTFELFNSI-------KDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLEAAK--PYCSNKIRFMIMNLMELRKDKWIPRKST-ESGPKKI Q7JMF0/517-761 -----------CKKVRSLMNKVTPTSQRPLTEEFISYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELSQT----------GGKSAFRNKVLTRTQMTFQDKK--DIDADKLAI---IEKEEDPVK---KELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKIVQTCTFELFNSI-------KDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLEAAK--PYCSNKIRFMIMNLMELRKDKWIPRKST-ESGPKKI A0A486WX07/522-766 -----------CKKVRSLMNKVTPTSQRPLTEEFISYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELSQT----------GGKSAFRNKVLTRTQMTFQDKK--DIDADKLAI---IEKEEDPVK---KELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKIVQTCTFELFNSI-------KDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLEAAK--PYCSNKIRFMIMNLMELRKDKWIPRKST-ESGPKKI A8IQZ3/14-259 ------------KTFKGILNKLTPDNYEKLKLQILAVQITHQKT-LEGFINQIFDKALIETTFSEMYANLCKEIHPNLPTFP----SNDPSSNKPVDFRRMLLNKCQQEFEDGTAAMQKVAASPSAPSVDDAKAKAQ---AEAAEAERELKARRRMLGNIQFIGHLYKCGLLTERIIHSCIVSLMQDT-------KSPR-------PDDIECLCKLLTTLGKQVCSER--NQNPMEVYFKRLRDLRESSNLDSRIKFAIQDVLDLRAAKWVSRRKA--EGPKRI A9SMV0/41-277 ------------RLIKGILNKLTPQNFDKLFVQVQEAKIDSATT-LTGVISQIFDKALMEPTFCEMYAQFCVKLAADLPEFN----EN----DEKITFKRVLLNKCQEEFERGEREQEEAEKDEE----EHVEIKMT---PEERE-EKRLKARRRMLGNIRFIGELYKKSMLTERIMHECIKKLLGEY-------HNPD-------EEDVEALCKLMSTIGRIIDHHK--AREHIDAYFRRMESLSNNTKLSARIRFLLKDVMELRRNGWQERRKV--DGPKKI F6SP01/97-342 -----------FRKVRGILNKLTPEKFDKLCLELLNVGVESKLI-LKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDIYDKRDN---------PLL---PEEE--EQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKK-------KRVQL--KDM-GEDLECLCQIMRTVGPRLDHER--AKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHNWVPRKAFLDNGPKTI H3G0K7/291-504_542-575 DESEETKKKLLLKTIRALFNKITPTTKDKLIDEFLAHKVYESPS-LSDVISIIFDKAVEEPKFCPLYSNMCHTQVQEELKLN----------NNVSLFRNAILIRAQETFTTKNLDDYVKEKQEE---IEAETDEKKKKEKQIELLEAQSKFRRRKFGNITFIGQLYLQQLISVRIILFCVVDLLKSV-----TEKPENLDGYEADEESVDCAVRLLETIGKRLQEES--ARASMDMTFQTLEGAI--PIVSSRIKFMIMNLVELRKNNWM------------- A0A2G5UXM8/557-808 -----------CKKVRSLMNKVTPTSQGPLTAEFISYNVSSNETQLTQVVEIVFDKAVEEPKFCALYAEMCKSQVTHELTKS----------NGKSAFRNTILTRTQSFFQDKR--DIDAEKLAV---IEKEEDPVK---REAMLIEEKQKFRRRKFGVMAFIGYLYRNSLLSTKIVQSCSLELFASILPKKIDEKEQPLKKEDFDEESIHCGLQLIETVGVILDKSKDPGPAFLDQWFKKLEDAK--PLCSNKIRFMIMNLNELRKDKWVPRKSV-ESGPKKI A8WN87/512-763 -----------CKKVRSLMNKVTPTSQGPLTAEFISYNVSSNESQLTQVVGIVFDKAVEEPKFCALYAEMCKAQVTHELAKS----------NGKSAFRNTILTRTQSFFQDKR--DIDAEKLAV---IEKEEDPVK---REAMLIEEKQKFRRRKFGVMAFIGYLYRNNLLSTKIVQSCSLELFASILPKKIDEKEQLLNKEDFDEESIHCGLQLIETVGVILDKSKDPGPAFLDQWFKKLEDAK--PLCSNKIRFMIMNLNELRKDKWVPRKSV-ESGPKKI A0A2J8UPW8/78-323 -----------FRKVRGILNKLTPEKFDKLCLELLNVGVESKLI-LKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKREN---------PLL---PEEE--EQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKK-------KRVQL--KDM-GEDLECLCQIMRTVGPRLDHER--AKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTI A0A2J8P5I5/78-323 -----------FRKVRGILNKLTPEKFDKLCLELLNVGVESKLI-LKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKREN---------PLL---PEEE--EQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKK-------KRVQL--KDM-GEDLECLCQIMRTVGPRLDHER--AKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTI A0A2A6B877/795-1008_1046-1079 DESEETKKKLLLKTIRALFNKITPTTKDKLIDEFLAHKVYESPS-LSDVISIIFDKAVEEPKFCPLYSNMCHTQVQEELKLN----------NNVSLFRNAILIRAQETFTTKNLDDYVKEKQEE---IEAETDEKKKKEKQIELLEAQSKFRRRKFGNITFIGQLYLQQLISVRIILFCVVDLLKSV-----TEKPENLDGYEADEESVDCAVRLLETIGKRLQEES--ARASMDMTFQTLEGAI--PIVSSRIKFMIMNLVELRKNNWM------------- A0A2G5UXY1/542-793 -----------CKKVRSLMNKVTPTSQGPLTAEFISYNVSSNETQLTQVVEIVFDKAVEEPKFCALYAEMCKSQVTHELTKS----------NGKSAFRNTILTRTQSFFQDKR--DIDAEKLAV---IEKEEDPVK---REAMLIEEKQKFRRRKFGVMAFIGYLYRNSLLSTKIVQSCSLELFASILPKKIDEKEQPLKKEDFDEESIHCGLQLIETVGVILDKSKDPGPAFLDQWFKKLEDAK--PLCSNKIRFMIMNLNELRKDKWVPRKSV-ESGPKKI A0A2G5UXN7/564-815 -----------CKKVRSLMNKVTPTSQGPLTAEFISYNVSSNETQLTQVVEIVFDKAVEEPKFCALYAEMCKSQVTHELTKS----------NGKSAFRNTILTRTQSFFQDKR--DIDAEKLAV---IEKEEDPVK---REAMLIEEKQKFRRRKFGVMAFIGYLYRNSLLSTKIVQSCSLELFASILPKKIDEKEQPLKKEDFDEESIHCGLQLIETVGVILDKSKDPGPAFLDQWFKKLEDAK--PLCSNKIRFMIMNLNELRKDKWVPRKSV-ESGPKKI A8WN89/341-592 -----------CKKVRSLMNKVTPTSQGPLTAEFISYNVSSNESQLTQVVGIVFDKAVEEPKFCALYTEMCKAQVIHELAKS----------MGKSAFRNTILTRTQSFFQDKR--DIDAEKLAI---IEKEEDPVK---REAMLIEEKQKFRRRKFGVVAFIGYLYRNNLLSAKHVHSCSLELFASILPKKIDEKEQLLNKKDFDEESIHCGLQLIETVGVILDNSKDPGPALLDQWFKKFEDAK--PLCSNKIRFMIMNLNELRKDKWVPRKSV-ESGPKKI #=GC scorecons 00000000000375685659969954345943755444846434194487357699966987764797569434535454340000100000444549853574749339556411434467343000342333544000473432945454757569564979495534865458553943496454000000183435123532585658446765979347645511544468549456445401424657979665654899545955653303366646 #=GC scorecons_70 ____________*_**_*_**_**_____*__*_____*_*____*__**__************_***_**__________________________**___*_*_*__*__________**___________________*____*_____*_*_**_*_***_*____**___*___*___*___________*___________*___*__**__***__**_________**__*__*___________****_*_*__***___*__*______***_* #=GC scorecons_80 ____________*__*___**_**_____*__*_____*______*__*_____***__**_*__***__*__________________________**_______*__*___________*___________________*____*_____*_*__*___***_*____*____*___*___*___________*___________*___*______*_*__*___________*__*_______________***______***___*______________ #=GC scorecons_90 ___________________**_**_____*_______________*________***__**_____*___*__________________________**_______*__*____________________________________*__________*___*_*_*____*____*___*___*___________*___________*__________*_*______________*__*_______________*_*______***___*______________ //